Global Dynamics of a Tuberculosis Epidemic Model and the Influence of Backward Bifurcation

In this paper, we propose and analyze a tuberculosis (TB) model with exogenous re-infection. We assume that treated individual may be again infected by infectious individual. The model exhibits two bifurcations viz. transcritical bifurcation when the basic reproductive number R ₀?=?1 and backward bifurcation where the disease transmission rate β plays as control parameter. The persistent of the model and, the local and global stability criteria of disease-free and endemic equilibria are discussed. By carrying out bifurcation analysis, it is shown that the model exhibits the bistability and undergoes the Hopf bifurcation when immunological memory is everlasting i.e. when σ?=?0. Lastly, some simulations are given to verify our analytical results.     

Integral geometry of translation invariant functionals,II: The case of general convex bodies

In continuation of Part I, we study translative integral formulas for certain translation invariant functionals, which are defined on general convex bodies. Again, we consider local extensions and use these to show that the translative formulas extend to arbitrary continuous and translation invariant valuations. Then, we discuss applications to Poisson particle processes and Boolean models which contain, as a special case, some new results for flag measures.     

Multi-mode resource availability cost problem with recruitment and release dates for resources

This paper investigates the multi-mode resource availability cost problem with recruitment and release dates for resources. This problem is a more realistic model and extended case of the resource availability cost problem. The project contains activities interrelated by finish–start precedence relations with zero time lags, which require a set of renewable resources. First, a mixed integer programming formulation is proposed for the problem. Then, simulated annealing (SA) algorithm is proposed to obtain a satisfying solution for this NP-hard problem. The effectiveness of the proposed algorithm is demonstrated through comprehensive experimentation based on 300 test problems. The results are analyzed and discussed.     

Projective embeddings of dual polar spaces arising from a class of alternative division rings

We discuss some recent results of us regarding a class of polar spaces which includes the nonembeddable polar spaces introduced by Tits [Tits, J., “Buildings of spherical type and finite BN-pairs,” Lecture Notes in Mathematics 386, Springer-Verlag, Berlin-New York, 1974]. These results include an elementary construction of the polar space, a construction of a polarized embedding of the corresponding dual polar space and the determination whether this projective embedding is universal and unique (as a polarized embedding).     

Dynamical behavior of computer virus on Internet

In this paper, we presented a computer virus model using an SIRS model and the threshold value R₀ determining whether the disease dies out is obtained. If R₀ is less than one, the disease-free equilibrium is globally asymptotically stable. By using the time delay as a bifurcation parameter, the local stability and Hopf bifurcation for the endemic state is investigated. Numerical results demonstrate that the system has periodic solution when time delay is larger than a critical values. The obtained results may provide some new insight to prevent the computer virus.     

Spread of a disease and its effect on population dynamics in an eco-epidemiological system

In this paper, an eco-epidemiological model with simple law of mass action and modified Holling type II functional response has been proposed and analyzed to understand how a disease may spread among natural populations. The proposed model is a modification of the model presented by Upadhyay et al. (2008) [1]. Existence of the equilibria and their stability analysis (linear and nonlinear) has been studied. The dynamical transitions in the model have been studied by identifying the existence of backward Hopf-bifurcations and demonstrated the period-doubling route to chaos when the death rate of predator (μ₁) and the growth rate of susceptible prey population (r) are treated as bifurcation parameters. Our studies show that the system exhibits deterministic chaos when some control parameters attain their critical values. Chaotic dynamics is depicted using the 2D parameter scans and bifurcation analysis. Possible implications of the results for disease eradication or its control are discussed.     

Frequency–energy plots of steady-state solutions for forced and damped systems,and vibration isolation by nonlinear mode localization

We study the structure of the periodic steady-state solutions of forced and damped strongly nonlinear coupled oscillators in the frequency–energy domain by constructing forced and damped frequency – energy plots (FEPs). Specifically, we analyze the steady periodic responses of a two degree-of-freedom system consisting of a grounded forced linear damped oscillator weakly coupled to a strongly nonlinear attachment under condition of 1:1 resonance. By performing complexification/averaging analysis we develop analytical approximations for strongly nonlinear steady-state responses. As an application, we examine vibration isolation of a harmonically forced linear oscillator by transferring and confining the steady-state vibration energy to the weakly coupled strongly nonlinear attachment, thereby drastically reducing its steady-state response. By comparing the nonlinear steady-state response of the linear oscillator to its corresponding frequency response function in the absence of a nonlinear attachment we demonstrate the efficacy of drastic vibration reduction through steady-state nonlinear targeted energy transfer. Hence, our study has practical implications for the effective passive vibration isolation of forced oscillators.     

Impulsive perturbations of a predator-prey system with modified Leslie-Gower and Holling type II schemes

In this paper, the dynamics of an impulsively controlled predator-prey model with modified Leslie-Gower and Holling type II schemes is analyzed. Choosing pest birth rate r ₁ as control parameter, we show that there exists a globally asymptotically stable pest-eradication periodic solution when r ₁ is less than some critical value $r_{1}^{*}$ and the system is permanent when r ₁ is larger than the critical value $r_{1}^{*}.$ By use of standard techniques of bifurcation theory, we prove that this threshold there are periodic oscillations in pest and predator. Furthermore, some situations which leads to chaotic behavior of the system are investigated by means of numerical simulations.     

A distance on curves modulo rigid transformations

We propose a geometric method for quantifying the difference between parametrized curves in Euclidean space by introducing a distance function on the space of parametrized curves up to rigid transformations (rotations and translations). Given two curves, the distance between them is defined as the infimum of an energy functional which, roughly speaking, measures the extent to which the jet field of the first curve needs to be rotated to match up with the jet field of the second curve. We show that this energy functional attains a global minimum on the appropriate function space, and we derive a set of first-order ODEs for the minimizer.     

Hopf bifurcation in epidemic models with a latent period and nonpermanent immunity

In this paper, some SEIRS epidemiological models with vaccination and temporary immunity are considered. First of all, previously published work is reviewed. In the next section, a general model with a constant contact rate and a density-dependent death rate is examined. The model is reformulated in terms of the proportions of susceptible, incubating, infectious, and immune individuals. Next the equilibrium and stability properties of this model are examined, assuming that the average duration of immunity exceeds the infectious period. There is a threshold parameter R_o and the disease can persist if and only if R_o exceeds one. The disease-free equilibrium always exists and is locally stable if R_o < 1 and unstable if R_o > 1. Conditions are derived for the global stability of the disease-free equilibrium. For R_o > 1, the endemic equilibrium is unique and locally asymptotically stable.For the full model dealing with numbers of individuals, there are two critical contact rates. These give conditions for the disease, respectively, to drive a population which would otherwise persist at a finite level or explode to extinction and to cause a population that would otherwise explode to be regulated at a finite level. If the contact rate β(N) is a monotone increasing function of the population size, then we find that there are now three threshold parameters which determine whether or not the disease can persist proportionally. Moreover, the endemic equilibrium need no longer be locally asymptotically stable. Instead stable limit cycles can arise by supercritical Hopf bifurcation from the endemic equilibrium as this equilibrium loses its stability. This is confirmed numerically.     

On the period of the limit cycles appearing in one-parameter bifurcations

The generic isolated bifurcations for one-parameter families of smooth planar vector fields {X_μ} which give rise to periodic orbits are: the Andronov-Hopf bifurcation, the bifurcation from a semi-stable periodic orbit, the saddle-node loop bifurcation and the saddle loop bifurcation. In this paper we obtain the dominant term of the asymptotic behaviour of the period of the limit cycles appearing in each of these bifurcations in terms of μ when we are near the bifurcation. The method used to study the first two bifurcations is also used to solve the same problem in another two situations: a generalization of the Andronov-Hopf bifurcation to vector fields starting with a special monodromic jet; and the Hopf bifurcation at infinity for families of polynomial vector fields.     

Mathematical study of a bacteria–fish model with level of infection structure

In this paper, we propose a mathematical model to study a bacteria–fish system, based upon the interactions between Clostridium botulinum and tilapia, Oerochromis mossambicus. The fish population is divided into susceptible and infected, and the infected fish population is considered structured by the level of infection. The model is thus a system with the infected fish equation being an evolution equation, while those corresponding to the susceptible fish and bacteria in water are ordinary differential equations. The model is firstly transformed into a system with distributed delay for susceptible fish and bacteria and, further, under some assumptions, into a system with discrete delay. The study of this system gives us some results concerning the existence, uniqueness, positivity and boundedness of solutions; we also discuss the existence and stability of its equilibrium points, including conditions for the appearance of Hopf bifurcation. The theoretical results are illustrated by some numerical simulations.     

Dynamical behavior of a virus dynamics model with CTL immune response

In this paper, the dynamical behavior of a virus dynamics model with CTL immune response is studied. Sufficient conditions for the asymptotical stability of a disease-free equilibrium, an immune-free equilibrium and an endemic equilibrium are obtained. We prove that there exists a threshold value of the infection rate b beyond which the endemic equilibrium bifurcates from the immune-free one. Still for increasing b values, the endemic equilibrium bifurcates towards a periodic solution. We further analyze the orbital stability of the periodic orbits arising from bifurcation by applying Poore’s condition. Numerical simulation with some hypothetical sets of data has been done to support the analytical findings.     

Bifurcation analysis of a population model and the resulting SIS epidemic model with delay

This paper deals with the model for matured population growth proposed in Cooke et al. [Interaction of matiration delay and nonlinear birth in population and epidemic models, J. Math. Biol. 39 (1999) 332–352] and the resulting SIS epidemic model. The dynamics of these two models are still largely undetermined, and in this paper, we perform some bifurcation analysis to the models. By applying the global bifurcation theory for functional differential equations, we are able to show that the population model allows multiple periodic solutions. For the SIS model, we obtain some local bifurcation results and derive formulas for determining the bifurcation direction and the stability of the bifurcated periodic solution.