一个肿瘤生长自由边界问题解的整体存在性和唯一性

该文研究一个反应扩散方程组的自由边界问题,它来源于描述抑制物作用下无坏死核肿瘤生长的数学模型.作者运用抛物型方程的L_p理论和压缩映照原理,证明了这个问题局部解的存在唯一性,然后用延拓方法得到了整体解的存在唯一性.     

一种肿瘤生长自由边界问题整体解的存在唯一性

研究了一种肿瘤生长模型中自由边界问题,该肿瘤生长模型异于其它此类模型之处就在于采用了新的方式来描述繁衍细胞和休眠细胞的运动．运用抛物型方程的Lp理论和不动点原理,证明了该模型存在唯一的整体解．     

一个肿瘤生长自由边界问题的研究

本文研究一个描述肿瘤生长的自由边界问题.这个自由边界问题是对Byrne和Chaplain相应肿瘤生长模型的一个改进,研究了该问题解当t→∞时的渐近状况,证明了未血管化的肿瘤体积不会无限制地增大,它或者趋于消失,或者趋于一个休眠态,依营养物浓度的大小和抑制物浓度的大小而定.     

一个肿瘤生长自由边界问题的研究

本文研究一个描述肿瘤生长的自由边界问题.这个自由边界问题是对Byrne和Chaplain相应肿瘤生长模型的一个改进,研究了该问题解当t→∞时的渐近状况,证明了未血管化的肿瘤体积不会无限制地增大,它或者趋于消失,或者趋于一个休眠态,依营养物浓度的大小和抑制物浓度的大小而定.     

一个肿瘤生长自由边界问题解的渐近性态

该文研究根据Byrne和Chaplain的思想建立的一个描述抑制物作用下无坏死核肿瘤生长的数学模型, 这个模型是一个非线性反应扩散方程组的自由边界问题. 作者运用反应扩散方程理论中的上下解方法结合自由边界问题的迭代技巧, 研究了解的渐近性态, 在营养物消耗函数f、抑制物消耗函数g和肿瘤细胞繁衍函数S的一些一般条件下,证明当常数c₁,c₂(肿瘤细胞分裂速率和营养物、抑制物扩散速率的比值)都非常小时,在一定的初边值条件下肿瘤趋于消失,在另外一些初边值条件下肿瘤半径趋于一个常数,进而时变解将趋于一个稳态解.     

肿瘤生长的自由边界问题

本文介绍肿瘤生长的自由边界问题这一新兴研究方向的研究内容和进展状况.文章首先介绍肿瘤生长的数学建模历史、最新进展和一些重要的肿瘤生长模型,这些模型的数学形式是偏微分方程的自由边界问题.之后介绍近几年人们对这些自由边界问题所做严谨数学理论分析获得的一些主要成果,并简单介绍了证明这些成果用到的数学理论和方法.     

拟线性双曲型方程组典型自由边界问题的整体经典解

本文对拟线性双曲组的某些典型边值问题及典型自由边界问题,证明了整体经典解的存在唯一性。     

一种未血管化肿瘤生长模型整体解的证明

研究了一种未血管化肿瘤生长模型的自由边界问题,模型与此类其它模型有着明显的不同,它引入新的运动项来描述肿瘤内细胞的运动,反映了肿瘤内细胞运动的"接触抑制"性质.运用Banach不动点理论和抛物型方程的L~P理论,证明了模型存在唯一整体解.     

一个关于肿瘤治疗的自由边界问题的数学分析

§1Introduction Avarietyofpartialdifferentialequationmodelsfortumorgrowthortherapyhave beendevelopedinthelastthreedecades[see2,3,16-18,21-26].Mostofthosemodelsare informoffreeboundaryproblems,andareverydiversified.Rigorousmathematical analysisofsuchfreeboundaryproblemshasdrawngreatinterest,andmanyinteresting resultshavebeenestablished[4-15].Inthispaperwedealwithamathematicalmodeldescribingtumorchemotherapy.In thismodelthetumorisviewedasdenselypacked,radially-symmetricsphereofradiusR(t)contain…     

一个早期肿瘤生长模型的数学分析

研究了乳腺癌的早期生长模型（DCIS）,它为耦合了抛物方程、椭圆方程的自由边界问题,运用椭圆型方程的变分理论、抛物方程的L^p理论和压缩映照原理,证明了这个问题局部解的存在惟一性,然后用延拓方法得到了整体解的存在惟一性。     

Analysis of a Free Boundary Problem Modeling Tumor Growth

In this paper, we study a free boundary problem arising from the modeling of tumor growth. The problem comprises two unknown functions： R = R（t）, the radius of the tumor, and u = u（r, t）, the concentration of nutrient in the tumor. The function u satisfies a nonlinear reaction diffusion equation in the region 0 〈 r 〈 R（t）, t 〉 0, and the function R satisfies a nonlinear integrodifferential equation containing u. Under some general conditions, we establish global existence of transient solutions, unique existence of a stationary solution, and convergence of transient solutions toward the stationary solution as t →∞.     

Global Existence for a Parabolic-hyperbolic Free Boundary Problem Modelling Tumor Growth

In this paper we study a free boundary problem modelling tumor growth, proposed by A. Friedman in 2004. This free boundary problem involves a nonlinear second-order parabolic equation describing the diffusion of nutrient in the tumor, and three nonlinear first-order hyperbolic equations describing the evolution of proliferative cells, quiescent cells and dead cells, respectively. By applying Lp theory of parabolic equations, the characteristic theory of hyperbolic equations, and the Banach fixed point theorem, we prove that this problem has a unique global classical solution.     

一个反应扩散方程整体解的存在性

对一个由反应扩散方程推出的抛物型自由边界问题进行了研究,该问题含有参数γ和τ,已证明了当γ充分大时,该问题存在唯一稳定解．现在主要证明γ,τ均充分大时,该问题存在整体解,即当0＜t＜ ∞时,该问题的解存在．     

Asymptotic Behaviour of Solutions of a Multidimensional Moving Boundary Problem Modeling Tumor Growth

We study a moving boundary problem modeling the growth of multicellular spheroids or in vitro tumors. This model consists of two elliptic equations describing the concentration of a nutrient and the distribution of the internal pressure in the tumor's body, respectively. The driving mechanism of the evolution of the tumor surface is governed by Darcy's law. Finally surface tension effects on the moving boundary are taken into account which are considered to counterbalance the internal pressure. To put our analysis on a solid basis, we first state a local well-posedness result for general initial data. However, the main purpose of our study is the investigation of the asymptotic behaviour of solutions as time goes to infinity. As a result of a centre manifold analysis, we prove that if the initial domain is sufficiently close to a Euclidean ball in the C ^m+μ-norm with m ≥ 3 and μ ∈ (0,1), then the solution exists globally and the corresponding domains converge exponentially fast to some (possibly shifted) ball, provided the surface tension coefficient γ is larger than a positive threshold value γ_*. In the case 0 < γ < γ_* the radially symmetric equilibrium is unstable.     

Riemann-Stieltjes积分边值问题正解的存在唯一性

利用解的先验估计和极值原理,研究了一类具有Riemann-Stieltjes积分边值问题正解的存在唯一性．     

Global Existence and Asymptotic Behavior of Solutions to a Free Boundary Problem for the 1D Viscous Radiative and Reactive Gas

In this paper, we study a free boundary problem for the 1D viscous radiative and reactive gas. We prove that for any large initial data, the problem admits a unique global generalized solution. Meanwhile, we obtain the time-asymptotic behavior of the global solutions. Our results improve and generalize the previous work.     

Existence and Nonuniqueness of Solutions to a Robin Boundary Problem for Semilinear Elliptic Equations

Sufficient conditions for existence and nonuniqueness of radially symmetric solutions to the Robin boundary problem of the form Δu + a(||x||)|u|^{-p} = 0 \qquad in B ⊂ R^N \frac{∂u}{∂n} + λu = -α \qquad on ∂B are obtained.     

Existence of Solutions of a Two-Point Boundary Value Problem

A two-point boundary value problem with a non-negative parameter Q arising in the study of surface tension induced flow of a liquid metal or semiconductor is studied. We prove that the problem has at least one solution for Q≥0.This improves a recent result that the problem has at least one solution for 0 ≤Q≤13.21.