共查询到20条相似文献,搜索用时 13 毫秒
1.
S. Vidhisha Kotha Laxma Reddy K. Ashwini Kumar Yata Praveen Kumar S. Satyanarayana 《Transition Metal Chemistry》2010,35(8):1027-1034
This article describes the synthesis of a polypyridyl ligand, namely 2-(2, 5-dimethoxyphenyl)-1H-imidazo[4,5-f]1,10-phenanthroline (DMPIP) and its Ru(II) complexes, namely [Ru(bipy)2DMPIP]2+ (1), [Ru(dmb)2DMPIP]2+ (2) and [Ru(phen)2DMPIP]2+ (3) ((bipy = 2,2′-bipyridine, dmb = 4,4′-dimethyl-2,2′-bipyridine, phen = 1,10-phenanthroline). The complexes were characterized
by elemental analysis, plus IR, 1H-NMR and 13C [1H]-NMR spectra. The interactions of the complexes with calf thymus DNA were investigated. The results indicate that the three
complexes can intercalate into DNA. Under irradiation at 365 nm, all three complexes promote the photocleavage of plasmid
pBR 322 DNA. Inhibitor studies suggest that singlet oxygen plays a significant role in the cleavage mechanism for the complexes. 相似文献
2.
Mohammad Rahimizadeh Mehdi Pordel Mehdi Bakavoli Zahra Bakhtiarpoor Ala Orafaie 《Monatshefte für Chemie / Chemical Monthly》2009,140(6):633-638
Abstract New imidazo[4,5-a]acridone derivatives were synthesized from the rearrangement of 3H-imidazo[4′,5′:3,4]benzo[c]isoxazoles. New imidazo[4,5-a]acridines were obtained from the reaction of imidazo[4,5-a]acridones in boiling POCl3. All of these compounds exhibited antimicrobial activities comparable to streptomycin as reference drug.
Graphical abstract
相似文献
3.
Fushan Yu Lingling Zhang Jinting Tan Xia Li Lijun Wang Fei Liu Xuwu Yang 《Chemical Papers》2011,65(1):23-28
A new complex, [Cu2(μ 2-Cl)2(IP)2Cl2] · 4H2O (IP = imidazo[4,5-f]1,10-phenathroline), was synthesised and characterised by elemental analysis, thermal analysis, IR spectra, and X-ray crystallography. The results showed that the complex crystallises in the monoclinic space group P \(\bar 1\); a = 7.880 (2) Å, b = 9.227(2) Å, c = 10.694(2) Å; α = 97.788(4)°, β = 100.637(4)°, γ = 95.841(3)°; V = 750.7(3) Å3, and Z = 1. The complex is further stabilised by H-bonds and a π-π stacking interaction between the pyridine and benzene rings of two neighbouring molecules with the centroid.centroid distance of 3.498(3) Å, leading to a 3D supramolecular architecture. Thermal decomposition procedure of the complex explored by TG-DTG has three stages, and the final product is Cu in residual rate of 16.18 % (calculated to be 16.26 %). 相似文献
4.
A. A. Harutyunyan 《Russian Journal of Organic Chemistry》2016,52(7):1012-1017
The reactions of benzene-1,2-diamine with 5-substituted 2-(alkylsulfanyl)-4-methylpyrimidin-6(1H)-ones and 2-(propylsulfanyl)- and 5-iodo-2-(propylsulfanyl)-3,4-dihydroquinazolines at 175–185°C under solvent-free conditions unexpectedly afforded benzo[4,5]imidazo[1,2-a]pyrimidine, benzo[4,5]imidazo[2,1-b]-quinazoline, and 2,2′-(benzene-1,2-diyldiimino)bis[pyrimidin-4(3H)-ones]. The described reaction is the first example of synthesis of these heterocyclic systems by fusion of benzimidazole to pyrimidine or quinazoline and is likely to follow ANRORC mechanism. 相似文献
5.
G. P. Kutrov N. V. Kovalenko Yu. M. Volovenko 《Russian Journal of Organic Chemistry》2008,44(2):257-262
2-Cyanomethyl derivatives were obtained of imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, and imidazo[2,1-b]thiazole, and their reactivity was investigated by an example of imidazo[1,2-a]pyridine: It was subjected to nitration, bromination, azo coupling and nitrosation. Acylation of the methylene group effected by amino acids esters with a subsequent addition of the amino group to the cyano group resulted in the formation of 5-amino-4-imidazo[1,2-a]-pyridin-2-yl-1-phenyl-1,2-dihydro-3H-pyrrol-3-one and 2-amino-1-ethyl-3-imidazol[1,2-a]pyridin-2-yl-4(1H)-quinolinone. 相似文献
6.
I. G. Davydenko Yu. L. Slominskii O. I. Kalchenko A. V. Gutov A. N. Chernega A. I. Tolmachev 《Russian Chemical Bulletin》2008,57(1):159-164
A procedure was developed for the synthesis of derivatives of the new heterocyclic system, benzo[cd]furo[2,3-f]indole, based on the cyclodehydration of 6-acylmethyloxy-1-alkyl-benzo[cd]indol-2(1H)-ones. Either 7- or 8-aryl derivatives of benzo[cd]furo[2,3-f]indol-4(5H)-ones can be prepared depending on the reaction conditions. The molecular and crystal structures of 7- and 8-phenylbenzo[cd]furo[2,3-f]indol-4(5H)-ones were established by X-ray diffraction. 相似文献
7.
S. A. Kuklin I. O. Konstantinov A. S. Peregudov I. E. Ostapov E. E. Makhaeva A. R. Khokhlov M. L. Keshtov 《Doklady Chemistry》2018,482(1):207-211
New derivatives of bis[1,3]thiazolo[4,5-f:5',4'-h]thieno[3,4-b]quinoxaline containing the fused thiadiazoloquinoxaline moiety have been prepared. Monomer M1 shows strong light absorption within 600–800 nm due to intramolecular charge transfer. The optical bandgap E g opt determined from the absorption edge in a film is 1.44 eV. The HOMO and LUMO levels are–5.44 and–3.12 eV, respectively. The new structural fragment has a rather low frontier molecular orbital energies and a small bandgap; therefore, it is a promising building block for the synthesis of polymers for organic electronics. 相似文献
8.
L. M. Potikha A. R. Turelyk V. A. Kovtunenko 《Chemistry of Heterocyclic Compounds》2011,47(6):745-754
Fusion of 4-bromo-1,3-diphenyl-2-buten-1-ones (γ-bromodypnones) with 1,2-dimethyl-1H-benzimidazole and further treatment of
the reaction product with a base (morpholine) gives 7,9-diaryl-5-methyl5,10-dihydroazepino[1,2-a]benzimidazol-11-ium bromides. The reaction of γ-bromodypnone with 1-alkyl-2-methyl-1H-imidazoles in benzene at 25 °C gives
quaternary azolium salts. Upon heating their solutions in alcohol in the presence of K2CO3 the latter cyclize to 1-R-6,8-diaryl-1,5-dihydroimidazo[1,2-a]azepin-4-ium bromides or 1-R-6,8-diaryl-1H-imidazo[1,2-a]azepines
depending on the nature of the substituent in the benzene rings and the substituent at the N(1) atom of the imidazole. 相似文献
9.
Previously unknown E isomers of azomethines (Schiff bases) were synthesized from vanillal and vanillin esters by their reaction with cyclohexylamine. 相似文献
10.
Mohammad Hossein Mosslemin Mohammad Reza Nateghi Razieh Mohebat 《Monatshefte für Chemie / Chemical Monthly》2008,139(10):1247-1250
A clean, simple, one-pot, and efficient synthesis of 1,2-dihydro-1-aryl[1,3]oxazino[5,6-f]quinolin-3-one and 1,2-dihydro-1-arylnaphtho[1,2-e]-[1,3]oxazine-3-one derivatives was accomplished in good yields via reaction between 6-quinolinol or 2-naphthol, aromatic aldehydes, and methyl carbamate in aqueous medium catalyzed by TEBA (triethylbenzylammonium chloride).
Correspondence: Mohammad Hossein Mosslemin, Department of Chemistry, Islamic Azad University, Yazd 8916871967, Iran. 相似文献
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12.
D. A. Köse G. Gökçe S. Gökçe İ. Uzun 《Journal of Thermal Analysis and Calorimetry》2009,95(1):247-251
Three novel mixed ligand complexes of Ni(II), Zn(II) and Cd(II) with p-chlorobenzote and N,N-diethylnicotinamide were synthesised and characterized on the basis of elemental analysis, FTIR spectroscopic
analysis, solid state UV-Vis spectrometric and magnetic susceptibility data. The thermal behavior of the complexes was studied
by simultaneous TG-DTA methods in static air atmosphere and the mass spectra data were recorded.
According to microanalytical results, formulas of complexes are C34H40N4O8ClNi, C34H40N4O8ClZn and C34H44N4O10ClCd. The complexes contain two moles of coordination waters, two moles p-chlorobenzoate and two mole N,N-diethylnicotinamide (dena) ligands per formula unit. In these complexes, the p-chlorobenzoate and N,N-diethylnicotinamide behave as monodentate ligand through acidic oxygen and nitrogen of pyridine ring.
The decomposition pathways and the stability of the complexes are interpreted in the terms of the structural data. The final
decomposition products were found to be as metal oxides. 相似文献
13.
V. A. Kuznetsov K. M. Shubin A. A. Shchipalkin F. S. Teplyakov M. L. Petrov 《Russian Journal of Organic Chemistry》2008,44(5):731-735
Efficient cyclization procedure was developed for 2-nitro-, 2,4-dinitro-, 2-nitro-5-chloro-, and 4,5-dichloro-2-nitrophenylhydrazines with 2-acylbenzoic acids by heating the reagents in a mixture of of concentrated sulfuric acid and ethanol. A series of new phthalazin-1-ones was obtained with a substituted 2-nitrophenyl group in the position 2 and various substituents in the position 4. 相似文献
14.
Sobhi M. Gomha 《Monatshefte für Chemie / Chemical Monthly》2009,140(2):213-220
Abstract The reaction of 2-mercapto-6,7,8,9-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one or its 2-methylthio derivative with hydrazonoyl halides, in the presence of triethylamine, yielded 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-ones. The structure of the latter compounds was further confirmed by reaction of 2-mercapto-6,7,8,9-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one with the appropriate active chloromethylenes followed by coupling of the products with benzenediazonium chloride
to afford the non-isolable azo-coupling products which converted, in situ, to 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-ones. The reaction mechanism was proposed and the products were screened for their biological activity. Some
of the newly synthesized compounds had a moderate effect against some bacterial and fungal species.
Graphical abstract
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15.
Novel pyrano[2,3-f]chromen-2,8-diones and pyrano[3,2-g]chromen-2,8-diones were prepared based on modified analogs of natural
o-hydroxyformyl(acyl)neoflavonoids.
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 15–20, January–February, 2008. 相似文献
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17.
E. V. Nosova G. N. Lipunova A. A. Laeva V. N. Charushin 《Russian Journal of Organic Chemistry》2005,41(11):1671-1677
Reactions of 2-aminothiazole, derivatives of 2-aminobenzothiazole and 2-aminobenzoimidazole with polyfluorobenzoyl chlorides gave rise to acylation products that at heating in the diphenyl ether formed fluoro-containing derivatives of thiazolo[3,2-a]-, benzothiazolo[3,2-a]-, and benzimidazo[3,2-a]quinazolinone. 相似文献
18.
Zh. V. Chirkova M. V. Kabanova S. I. Filimonov S. S. Sergeev E. A. Smirnova T. N. Sudzilovskaya 《Russian Journal of Organic Chemistry》2017,53(2):192-198
General methods were developed of the synthesis of N-substituted 1-hydroxypyrrolo[3,4-f]indole-5,7-diones using as initial compounds substituted 6-nitroisoindole-1,3-diones and 5-nitro-4-phenacylphtalic acids. 相似文献
19.
A. H. Kategaonkar S. B. Sapkal B. R. Madje B. B. Shingate M. S. Shingare 《Chemistry of Heterocyclic Compounds》2010,46(6):754-758
Some new 4,5-diphenyl-1H-imidazole derivatives were synthesized in good yields by treating various tetrazolo[1,5-a]quinolines with benzil and ammonium acetate in glacial acetic acid. 相似文献
20.
I. G. Filippova Yu. A. Simonov M. Gdanets V. Stavila 《Journal of Structural Chemistry》2005,46(6):1095-1098
The structure of tris(1,10-phenanthroline)iron(II) dinitrate dihydrate [Fe(phen)3](NO3)2·2H2O was established by X-ray diffraction analysis. The role of hydrogen bonds in crystal packing is discussed. 相似文献