Stereoselektive Synthese des Nitrit-reduzierenden Cofaktors Häm d1 ausgehend von Hämatoporphyrin

Steroselective Synthesis of the Nitrite-Reducing Cofactor Heme d₁ from Hematoporphyrin The nitrite-reducing cofactor heme d₁ has been synthesized in a few synthetic steps, starting from readily accessible hematoporphrin dimethyl ester (rac- 4a ). A single-crystal structure analysis of the synthesized target molecule rac- 10a unequivocally established the constitution and the relative configuration of heme d₁ ( 3 ).     

Händigkeit – leben in einer chiralen Welt

We may “live in a material world” as claimed by Madonna but we definitely evolve in a chiral one. As we are born into a chiral environment, where a lot of objects are not identical with their mirror images, we most naturally and often unconsciously adapt to it. It is only when one exchanges for example the corkscrewer by its left‐handed counterpart that we actually notice that something is not as usual. We will – supported by six practical experiments – explain to you and guide you through the fascinating world of chirality.