微波辐射下1-氨基烷基膦酸酯的一锅合成

以醛、胺及膦酸二乙酯为原料,微波辐射3min～5min,高产率地一锅合成了一系列的1．氨基烷基膦酸酯。其结构经^1HNMR,IR和元素分析表征。     

利用微波辐射制备2-萘甲醚的合成实验

利用微波辐射的方法合成 2 萘甲醚 ,对微波辐射功率、微波辐射时间、催化剂的用量、反应物的配比对反应产率的影响进行讨论 ,该方法与传统合成方法相比具有反应时间短 ,反应条件温和 ,简单易行 ,无污染的特点     

微波辅助下5-氟尿嘧啶-1-基乙酸的绿色合成

在微波辐射下,以水作溶剂,以氯乙酸、5-氟尿嘧啶为原料合成了具有重要生理活性的标题化合物5-氟尿嘧啶1-基乙酸．产率86．8％．该方法反应时间短,分离方便,产品纯度高．     

The Rapid Synthesis of Schiff-Base without Solvent under Microwave Irradiation

The chemistry of the carbon-nitrogen double bond plays a vital role in the progresses of chemistry science1. Schiff-base compounds have been used as fine chemicals and medical substrates. Recently multi-dentate complexes of iron and nickel showed high activities of ethylene oligomerization and polymerization2. In our efforts for ligands of polymerization catalysts, synthesis of Schiff-base through classical condensation of aldehydes (or ketones) and amines were pursued, however, the yield o…     

Synthesis of Thiosemicarbazones Under Microwave Irradiation

Thiosemicarbazones (3) are effectively synthesized in a few minutes by the condensation reaction of aldehydes with thiosemicarbazide under microwave irradiation.     

Green Synthesis of Some Calix[4]Resorcinarene Under Microwave Irradiation

A green synthetic procedure for the preparation of some calix[4]resorcinarenes using a household microwave oven has been carried out. This method represents a very rapid heating alternative to the conventional method that involves very long time of reactions (from 20-24 h in conventional heating to 5-8 min in microwave irradiation). C-4-hydroxy–3-methoxycalix[4]resorcinarene (CHMPCR), C-4-methoxyphenylcalix[4]resorcinarene (CMPCR) and C-2–phenylethenilcalix[4]resorcinarene (CPECR) was achieved by placed of resorcinol, an aldehyde, HCl and ethanol inside a household microwave oven. The product was recrystallized by methanol and analyzed by spectral analysis (FTIR, H-NMR and MS). Optimization of reaction was carried out in variation of microwave power, reaction times and reactant composition. The result shows that optimum condition of synthesis of C-4-hydroxy-3–methoxycalix[4]resorcinarene (CHMPCR) with microwave irradiation were at microwave power 332 W, reaction time 8 min and the mole ratio of resorcinol and 4-hydroxy-3-methoxyphenylbenzaldehyde 1:1. This parameter gave product in 97.8% (53.7% after recrystallization). The CPECR synthesis using resorcinol and cynnamaldehyde (1:1) at microwave power 332 W for 5 min afforded the product in 97.3% (44.5% after recrystallization). Whereas the reaction of resorcinol and 4-methoxyphenylbenzaldehyde (1:1.2) at microwave power 264 W for 5 min gave CMPCR in 99.5% (68.6% after recrystallization).     

Synthesis of Guanylhydrazones Under Microwave Irradiation

Abstract

The reaction of aromatic aldehydes and ketones with aminoguanidine hydrochloride under microwave irradiation (MWI) afforded guanylhydrazones in shorter reaction times and improved yield as compared to the conventional methodology.     

An Efficient One-Pot Synthesis of Nitriles from Carboxylic Acids Without Solvent Under Microwave Irradiation

Nitriles were prepared from alkyl and aryl carboxylic acids in dry media conditions, under microwave irradiation. Heating of the carboxylic acid, urea and amidosulfonic acid adsorbed on alumina support in a microwave oven affords nitriles in 20–93% yields.     

Synthesis of Jasminaldehyde by Solid-Liquid Phase Transfer Catalysis Without Solvent,Under Microwave Irradiation

α-n-amylcinnamaldehyde (jasminaldehyde) was obtained with 82 % yield by solid-liquid phase transfer catalysis without solvent within 3 days at room temperature. By use of domestic microwave irradiation, the same yield was obtained within 1 minute at a power of 600 W.     

N-烃基邻苯二甲酰亚胺的微波干法催化合成

在K2 CO3 固体碱催化下 ,利用微波辐射 ,邻苯二甲酰亚胺和卤代烃发生取代反应 ,高产率地合成了N -烃基邻苯二甲酰亚胺     

Improved Synthesis of Oxadiazoles Under Microwave Irradiation

Abstract

Amidoximes (1) reacted with isopropenyl acetate in presence of KSF under microwave irradiation and gave 1,2,4-oxadiazoles (2). 1,2,4-Oxadiazoles (4) can also be obtained by microwave irradiation from O-acylamidoximes (3) adsorbed on Alumina.

1,3,4-Oxadiazoles (6) were obtained by irradiation of bis (acyl) hydrazines (5) in thionyl chloride.     

微波辐射下苯并噁唑基吡啶的合成

在微波辐射条件下,利用邻氨基酚和吡啶羧酸在多聚磷酸中的缩合反应,合成了2种苯并唑基取代吡啶 最佳反应条件为:450W辐射4min 相比于常规反应,反应时间大为缩短且产率令人满意     

2,4,6-三芳基吡啶的微波辐射促进合成

微波辐射;查尔酮;缩合反应;吡啶;叶立德     

3,4-Dihydropyrimidin-2(1H)-Ones: Fast Synthesis Under Microwave Irradiation in Solvent Free Conditions

Microwave irradiation has been used to accelerate the synthesis of the Biginelli compounds, in one-pot reaction between β-keto esters, aryl aldehydes, and urea. These solvent-free reactions show that it is possible to prepare these compounds in a short time reaction and with good yield and easily isolable.     

A Facile One Stage Synthesis of Oxazolines Under Microwave Irradiation

A rapid, high yielding procedure for the synthesis of 2-substituted oxazolines has been achieved under microwave irradiation from alkyl and aryl nitriles and β-amino alcohols using a mild Lewis acid catalyst.     

Simultaneous Synthesis of Pyrazolopyridines and Pyrazolopyrimidinones Under Microwave Irradiation

The direct reaction of o-aminopyrazocarbonitriles and carbonyl compounds to afford pyrazolopyrimidinones was discovered; hence, a simultaneous synthetic method for pyrazolopyridines and pyrazolopyrimidinones was achieved. Under microwave irradiation, better yields of products than those of conventional method were given.     

3-甲基吡啶的微波液相法合成

在液相条件下,采用微波协助合成3-甲基吡啶（1）,其结构经GC-MS确证。研究了碳源(甘油、丙烯醛二甲缩醛和丙烯醛二乙缩醛)、氨源(硫酸亚铁铵、乙酸铵和氨水)、固体催化剂用量和溶剂(水、离子液体、二乙二醇甲醚、乙二醇丁醚和二甲基亚砜)对1合成反应的影响。结果表明：丙烯醛是重要的中间产物;在多相催化体系下,1收率最高可达到19.8%。     

Rapid Synthesis of Alkyloxy Porphyrins Under Microwave Irradiation

Alkyloxy porphyrins have been prepared by direct coupling of 5-para-hydroxyphenyl-10,15,20-triphenylporphyrin and alkyl halides under microwave irradiation within several minutes. The length of the alkyl halides has no obvious effect on the yields and reaction time; however, the steric structure of the alkyl halides has a great impact on the reaction time. All the products were confirmed by ¹H NMR.     

无溶剂条件下微波辐射合成2-氨基噻唑衍生物

在无溶剂条件下, 用微波辐射法以碘、酮和硫脲为原料合成了9个2-氨基噻唑衍生物. 利用正交法优化了微波促进此类环化反应的最佳条件, 提出了微波条件下碘催化环化合成2-氨基噻唑衍生物可能的反应机理.     

A Convenient One-Pot Synthesis of Dibenzyl Diselenides Under Microwave Irradiation Conditions

A simple, rapid and efficient method for the synthesis of dibenzyl diselenides under microwave irradiation is reported. The effect of microwave irradiation power, times and solvent on the reaction is investigated.