可见分光光度法直接测定药物青藤碱

研究了在氢氧化钠溶液中盐酸青藤碱的可见吸收光谱.采用可见分光光度法测定盐酸青藤碱药片的含量.实验发现,盐酸青藤碱在氢氧化钠溶液中最大吸收波长为454nm,表观摩尔吸光系数是1.292×105L · mol-1,cm-1,选择氢氧化钠底液为0.3mol·L-1,加热温度为70℃,加热时间为25min.在最佳实验条件下,盐酸青藤碱浓度在4×10-5-2.5×10-4mol·L-1范围内符合比耳定律.本法测量盐酸青藤碱简单、快速、成本低、灵敏度高,并直接用于药品中盐酸青藤碱的含量测定,结果令人满意.     

狭叶红景天中7种无机元素的含量测定及比较研究

采用原子吸收光谱法分别测定野生和种植狭叶红景天及大花红景天中K、Ca、Mg、Fe、Mn、Zn、Cu 7种元素的含量,观察3种药材各元素的含量及差异。结果显示,野生和种植狭叶红景天各元素含量大小顺序均为KMgCaFeMnZnCu,除Mn外,种植狭叶红景天中的其他各元素均高于野生,结果表明,种植与野生的狭叶红景天无机成分无明显差异;而大花红景天中Ca的含量最高,除Ca以外的其他各元素含量大小顺序则与狭叶红景天相同;狭叶红景天中Fe、Cu、Zn、Mg、K的含量丰富,且明显高于大花红景天;而大花红景天中Ca、Mn的含量则高于狭叶红景天。为研究狭叶红景天中无机元素与疗效的内在关系以及对其合理药用提供可靠依据。     

盐酸青藤碱肠溶片的健康人体生物等效性

建立了测定人血浆中盐酸青藤碱的高效液相色谱法(HPLC),研究盐酸青藤碱肠溶片在男性健康志愿者体内的药动学行为,评价其人体相对生物利用度和生物等效性.18例健康男性志愿者随机分组自身交叉对照试验设计,单剂量口服盐酸青藤碱肠溶片受试制剂和参比制剂80mg,HPLC测定服药后36h内不同时间血浆中盐酸青藤碱的浓度,BAPP药动学程序计算相对生物利用度并评价两种制剂生物等效性.受试制剂和参比制剂的主要药动学参数:tmax分别为(2.36±0.64)h和(2.56±0.62)h;Cmax分别为(838.05±145.78)ng·mL-1和(819.46±105.77)ng·mL-1;t1/2分别为(11.29±1.95)h和(10.10±2.75)h,药时曲线下面积AUC(0→36h)分别为(5850.39±1805.83)ng·h·mL-1和(6134.85±1862.25)ng·h·mL-1.受试制剂与参比制剂的相对生物利用度为(101.1±36.1)％.建立的分析方法准确灵敏,测得的数据可靠,统计学分析表明两种制剂生物等效.     

傅里叶变换红外光谱法和紫外-可见谱线组法分析广西特产罗汉果

采用红外光谱和紫外-可见谱线组法全面分析了广西特产罗汉果,并将紫外-可见谱线组法延伸至红外光谱,采集了4种浸泡液的红外谱图。罗汉果红外光谱中出现了羟基、亚甲基、链状羧酸酯羰基、酰胺和苷键的特征吸收峰,表明其中主要含有油脂、蛋白质和甜甙等成分。4种不同极性溶剂水、乙醇、氯仿和石油醚浸泡液的紫外-可见谱线中吸收峰个数、峰形和峰位都存在很大差别,全面反映出罗汉果所含成分的整体效应。4种浸泡液的红外谱图中分别出现了不同成分的特征峰,说明水浸泡液中含有蛋白质和甜甙等极性分子,乙醇浸泡液中既含有蛋白质、甜甙,也含有油脂等脂溶性成分,氯仿浸泡液中除了含有大量油脂,还含有少量蛋白质等成分,而石油醚浸泡液中只含有油脂等脂溶性成分。     

光谱法测定野生植物乌楣的营养成分

本文对野生植物乌楣的营养成分进行了分析 ,结果表明 ,乌楣中含有多种营养成分 ,丰富的矿质元素和维生素及β-胡萝卜素。乌楣中至少含有 1 7种氨基酸。该研究为开发利用植物资源提供了科学依据     

野生植物五月瓜藤的营养成分

对野生植物五月瓜藤的营养成分进行了分析 ,五月瓜藤中含有多种营养成分 ,丰富的矿物质元素和维生素及 β-胡萝卜素 ,至少含有 1 7种氨基酸。为开发利用植物资源提供了科学依据     

野生植物三桠苦的营养成分

本文对野生植物三桠苦的营养成分进行了分析 ,三桠苦中含有多种营养成分 ,丰富的矿质元素和维生素及 β-胡萝卜素 ,其中至少含有 1 7种氨基酸。为开发利用该植物提供了科学依据。     

葛酒中葛根素及其挥发性成分分析

HPL C法定量测定了葛酒中葛根素的含量 ,葛酒中含有一定量的异黄酮类化合物葛根素 ,相同品牌不同生产批号葛酒中的葛根素含量相对稳定 ,可作为葛酒质量控制的分析方法。对葛酒中挥发性成分采用气相色谱 -质谱 (GC- MS)联机进行定性分析 ,鉴定出 10个组分。与白酒中挥发性成分比较 ,葛酒中除了含有己酸乙酯等白酒中具有的相同成分之外 ,还含有酸、酮等化合物 ,与传统的白酒工艺相比 ,葛酒的酿造过程具有一定特色。     

同步荧光光谱方法测定柴油中的溶剂油

同步荧光光谱方法与表面荧光技术结合,研究了柴油中混120#溶剂油的荧光光谱.通过佑发射峰位置蓝移程度可以快速分析出柴油中是否含有120#溶剂油,并发现含有120#溶剂油的柴油其发射峰相对纯柴油的发射峰偏移量与柴油中含有120#溶剂油的百分含量具有一定的关系.通过这种关系可以定性的判断出柴油中掺杂120#溶剂油的多少,这对于分析市场上柴油的真伪、维护市场稳定具有重要的意义.     

斑头雁脂肪酸的气相色谱-质谱分析

采用冷冻干燥和改进的Bligh-Dyer方法提取脂肪酸,用GC-MS测定了斑头雁腿肌、胸肌组织和卵的脂肪酸组成情况,含有脂肪酸27种,均为长链脂肪酸(C14.0以上).其中饱和脂肪酸19种,占总含量的80.577％-87.701 ％;不饱和脂肪酸8种,占脂肪酸总含量的12.298％-19.423％.在斑头雁的腿肌、胸肌和卵组织中,脂肪酸组成差异不大(P＜0.05).肌肉中含有的脂肪酸种类要多于卵组织中含有的脂肪酸种类.在斑头雁组织含有10种带有甲氧基的脂肪酸,分别占腿肌脂肪酸总量的36.175％,胸肌脂肪酸的10.401％,卵脂肪酸的45.339％.     

Guided-Wave Two-Dimensional Acousto-Optic Scanner Using Proton-Exchanged Lithium Niobate Waveguide

Two-dimensional scanning of a 0.6328 mum guided-light beam has been realized using noncolinear acousto-optic (AO) coplanar Bragg diffraction together with colinear AO guided-mode to substrate radiation-mode conversion in a Z-cut Xpropagation LiNbO3 proton-exchanged (PE) waveguide. The two surface acoustic (SAW) waves utilized are at the center frequencies of 500 and 200 MHz, propagating in the Y and X axes, respectively. Two-dimensional scanning of approximately 720 resolvable light beam spots, namely, 18 40 (horizontal vertical) scanning, has been demonstrated using a light beam of 1.0 mm aperture. The total number of resolvable beam spots can be greatly increased from 720 by simply utilizing SAW transducers of larger bandwidth and a light beam of greater aperture. It should also be possible to significantly increase the diffraction efficiency from 3 % by optimizing the parameters of the PE waveguide and the SAWs.     

Hybrid Wavelength and Code Division Multiple Access in Optical Networks

A review of schemes for multiple access in fiber optic networks shows that a hybrid of wavelength and code division multiple access (WCDMA) combines the best features of both. In particular, the hybrid scheme retains the large information carrying capacity of wavelength division multiple access (WDMA) and flexibility of code division multiple access (CDMA). In this paper WDMA, optical CDMA (OCDMA), and WCDMA networks are discussed. In OCDMA networks, concept of incoherent and coherent coding including inverse decoding and matched filter is introduced. The delay performance of both WDMA and WCDMA networks, under the simple suboptimum access protocols based on cyclic search, is computed. It has been shown quantitatively that tuning delay significantly affects the delay performance of both WDMA and WCDMA networks. Futhermore, delay performance of WCDMA networks is always better than the WDMA networks for the same tuning delay, load, and number of users.     

Effect ofγ-radiation on the spectral luminescence characteristics of impure cadmium tungstate crystals

Results of a study of the effect of γ-radiation on the spectral luminescence properties of cadmium tungstate crystals doped with silver, bismuth, and molybdenum cations are presented. Spectral characteristics of the nondnnnoped crystals are briefly described. Absorption and photo and X-ray luminescence spectra of the crystals taken before and after exposure to γ-radiation (5.5·10⁴ Gy) are compared. It is found that the spectral characteristics of the crystals doped with silver, bismuth, and molybdenum cations do not change markedly after the exposure. The relation between the type of impurity-induced defects, individual characteristics of the impurity cations, and the character of the effect of γ-radiation on the spectral luminescence properties of impure crystals is analyzed (preliminarily). Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 64, No. 1, pp. 55–60, January–February, 1997.     

Femtosecond Transform-Limited Pulse Generation by Compensating for the Linear Chirp of SPM Spectra in Dispersion Shifted Fibers

A simple technique of pulse compression, based on the linear chirp compensation of self-phase modulation (SPM) spectra in dispersion shifted fibers, is demonstrated. The optimization procedure is carried out, for a short span of a single-mode fiber, using a parabolic law, which describes the behavior of the squared output pulse width versus the pump peak power in the case of Gaussian pulses. The experimental results give a minimum pulse duration of 233 fs, which is in good agreement with the model. Shorter and coherent pulses, down to 90 fs, have been obtained by inserting an interference filter at the optical output.     

Sorting of bending magnets for the SSRF booster

The Shanghai Synchrotron Radiation Facility(SSRF)booster ring,a full energy injector for the storage ring,is deigned to accelerate the electron beam energy from 150MeV to 3.5GeV that demands high extraction efficiency at the extraction energy with low beam loss rate when electrons are ramping.Closed orbit distortion(COD)caused by bending magnet field uniformity errors which affects the machine performance harmfully could be effectively reduced by bending magnet location sorting.Considering the affections of random errors in measurement,both ideal sorting and realistic sorting are studied based on measured bending magnet field uniformity errors and one reasonable combination of bending magnets which can reduce the horizontal COD by a factor of 5is given as the final installation sequence of the booster bending magnets in this paper.     

Measurement of nonlinear coefficient of optical fiber based on small chirped soliton transmission

We measure the waveform and phase curves of short optical pulses before and after transmission over different lengths of fibers by use of the pulse analyzer with the frequency-resolved optical gating (FROG),and numerically simulate pulse evolution under the experimental conditions.The nonlinear coefficient of the fiber is given by comparing the experimental results with the numerical ones.Difference between the experiment and numerical simulation is analyzed.     

Resonance scattering of canonical elastic shells in absorbing fluid medium

Resonance scattering of elastic spherical shell and cylindrical shell while the surrounding fluid medium has absorption is studied. The normal mode solution derived using exact elastic theory and the separation of variables is still applicable. However, the scattering form function has to be modified for the absorbing medium, otherwise the unreasonable result would be obtained. The backscattering form function in the absorbing medium is redefined, and the form function of elastic spherical and cylindrical shell with vacuum or solid matter filled is calculated in various absorption conditions. The results show that the absorption of surrounding fluid leads to notable attenuation of the coincidence resonances in the mid-frequency, but it has a little influence on the low-frequency resonance scattering induced by the filler inside the shell.     

Single-beam self-referenced phase-sensitive surface plasmon resonance sensor with high detection resolution

A versatile and low-cost single-beam self-referenced phase-sensitive surface plasmon resonance(SPR)sensing system with ultra-high resolution performance is presented.The system exhibits a root-mean-square phase fluctuation of ±0.0028.over a period of 45 min.i.e.a resolution of±5.2×10-9 refractive index units.The enhanced performance has been achieved through the incorporation of three design elements:a true single-beam configuration enabling complete self-referencing so that only the phase change associated with SPR gets detected,a differential measurement scheme to eliminate spurious signals not related to the sensor response,and the elimination of retardation drifts by incorporating temperature stabilization in the liquid crystal phase modulato .Our design should bring the detection sensitivity of non-labeling SPR biosensing closer to that achievable by conventional fluorescence-based techniques.     

Influences of SiO2 protective layers and annealing on the laser-induced damage threshold of Ta2O5 films

Ta2O5 films are prepared on BK7 substrates with conventional electron beam evaporation deposition.The effects of SiO2 protective layers and annealing on the laser-induced damage threshold (LIDT) of the films are investigated.The results show that SiO2 protective layers exert little influence on the electric field intensity(EFI)distribution,microstructure and microdefect density but increase the absorption slightly.Annealing iS effective on decreasing the microdefect density and the absorption of the films.Both SiO2 protective layers and annealing are beneficial to the damage resistance of the films and the latter is more effective to improve the LIDT.Moreover,the maximal LIDT of Ta2O5 films is achieved by the combination of SiO2 protective layers and annealing.