共查询到20条相似文献,搜索用时 15 毫秒
1.
Summary. A series of 6- and 7-substituted derivatives of 1,3-diaminoisoquinoline were synthesized by the reaction of N,N-diethylarylacetamides with POCl3 and then with N,N-dimethylcyanamide. The products were identified by means of spectroscopic methods and their pK
a
dissociation constants were determined.
Corresponding author. E-mail: kudelkoa@zeus.polsl.gliwice.pl
Received July 7, 2002; accepted July 22, 2002 相似文献
2.
Iveta Kmentová Battsengel Gotov Vladimír Gajda Štefan Toma 《Monatshefte für Chemie / Chemical Monthly》2003,134(4):545-549
Summary. The Sonogashira reaction of iodobenzene with phenylacetylene in several room temperature ionic liquids was studied. A regeneration of the
catalytical system immobilized in 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) has been also investigated. The reactivity of different iodoarenes with terminal alkynes in [bmim]PF6 was studied as well.
Corresponding author. E-mail: toma@fns.uniba.sk
Received September 2, 2002; accepted September 9, 2002 相似文献
3.
Shadpour Mallakpour Abdol Reza Hajipour Hedayat A. Taghizadeh 《Monatshefte für Chemie / Chemical Monthly》2003,134(7):1015-1017
Summary. A rapid and simple method for the preparation of 4-substituted 1-ethoxycarbonyl semicarbazide is reported. The reaction is
carried out under microwave irradiation by the reaction of five different isocyanates with ethyl carbazate.
Corresponding author. E-mail: mallak@cc.iut.ac.ir
Previous name. Shadpour E. Mallakpour
Received October 28, 2002; accepted October 31, 2002
Published online May 15, 2003 相似文献
4.
Huda A. R. Farid Olaf Kunert Ernst Haslinger Christoph Seger 《Monatshefte für Chemie / Chemical Monthly》2002,133(11):1453-1458
Summary. Besides a known coumarin derivative, scopoletin, the iridoids gardenoside, α- and β-gardiol were isolated for the first time
from a Xeromphis species, namely Xeromphis nilotica. Their structures were established on the basis of their spectroscopic data.
Corresponding author. E-mail: christoph.seger@uni-graz.at
Received May 6, 2002; accepted (revised) May 29, 2002 相似文献
5.
Herman Gershon Donald D. Clarke Muriel Gershon 《Monatshefte für Chemie / Chemical Monthly》2002,133(11):1437-1442
Summary. 6-Fluoro-8-quinolinol was prepared from 2-amino-5-fluorophenol by a Skraup synthesis. No synergism was observed between 5-fluoro- and 6-fluoro-8-quinolinols or between 6-fluoro- and 7-fluoro-8-quinolinols
against any of the six fungi in our test system (Aspergillus niger, A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth. Unlike the fluoro-8-quinolinols, the 8-quinolinols comparably substituted with chlorine or bromine did form
synergistic mixtures. This is attributed to steric factors.
Corresponding author. E-mail: clarke@fordham.edu
Received May 23, 2002; accepted May 29, 2002 相似文献
6.
Summary. The indolizidinium alkaloid ipalbidinium and the quinolizidinium alkaloid clathryimine B were prepared starting from brominated
2-aminopyridines using two Pd-catalyzed cross-coupling reactions and a Sandmeyer-type diazotation/iodination protocol as the key steps.
Corresponding author. E-mail: Franz.Bracher@cup.uni-muenchen.de
Received August 2, 2002; accepted August 9, 2002 相似文献
7.
Saeed Balalaie Elahe Kowsari Mehri S. Hashtroudi 《Monatshefte für Chemie / Chemical Monthly》2003,134(3):453-456
Summary. Three component condensation of alkylacetoacetates, primary amines, and alkyl cyanoacetates catalyzed by solid supports under
microwave irradiation gave N-alkyl 3-cyano-6-hydroxy-2(1H)-pyridinones with high yields. Upon carrying out the reaction under the same condition on acidic alumina, zeolite HY, silica
gel, and montmorillonite K-10, the best yields were achieved by silica gel.
Corresponding author. E-mail: balalaie@yahoo.com
Received August 28, 2002; accepted September 3, 2002 相似文献
8.
Stefan E. Boiadjiev David A. Lightner 《Monatshefte für Chemie / Chemical Monthly》2003,134(4):489-499
Summary. Pyrrole α-aldehydes (2-formyl-4,5-dimethyl-1H-pyrrole and 2-formyl-N-methylpyrrole) condense readily at C(3) of indolin-2-ones to give dipyrrinone analogs, such as (3Z)-[(4,5-dimethylpyrrol-2-yl)-methylidenyl]-indolin-2-one and (3E)-[(1-methylpyrrol-2-yl)-methylidenyl]-indolin-2-one. 1H-NMR NOE analyses and X-ray crystallography confirm the syn-(Z) configuration for the former and the syn-(E) configuration for the latter. The former is stabilized by intramolecular hydrogen bonding. Molecular mechanics calculations
of the latter indicate no energy difference between the syn and anti conformations.
Corresponding author. E-mail: lightner@scs.unr.edu
Received August 2, 2002; accepted August 30, 2002 相似文献
9.
Adam Bieniek Jan Epsztajn Mieczysław W. Płotka 《Monatshefte für Chemie / Chemical Monthly》2003,134(4):533-538
Summary. A convenient two step protocol preparation of ortho-phenylthiomethyl aromatic carboxylic acids from aromatic carboxylic acids anilides is reported. The phenylthiolation of phthalides
with benzenethiol as a key step is described.
Corresponding author. E-mail: epsztajn@krysia.uni.lodz.pl
Received June 21, 2002; accepted July 9, 2002 相似文献
10.
Mosselhi Mosselhi A. N. Tawfik Nagla M. Shawali Ahmad S. 《Monatshefte für Chemie / Chemical Monthly》2003,134(4):565-571
Summary. A convenient synthesis of 3-substituted [1,2,4]triazolo[4,3-e]caffeines by oxidative cyclization of 8-arylmethylenehydrazinocaffeines with bromine in acetic acid in presence of sodium
acetate is described.
Corresponding author. E-mail: haney_sami@mail.com
Received May 6, 2002; accepted June 13, 2002 相似文献
11.
Summary. A 1:1 molar ratio of the cobalt and manganese salts of p-amino benzoic acid supported on silica gel is an effective catalyst for the oxidation of various organic compounds in reasonable
yields using molecular oxygen. The catalyst can be reused several times.
Corresponding author. E-mail: mhashemi@sharif.edu
Received April 30, 2002; accepted (revised) July 16, 2002 相似文献
12.
Summary. The first optically active taurine conjugate of a bilirubin was prepared by reaction of taurine sodium salt with the mixed
anhydride formed from reaction of (βS,β′S)-dimethylmesobilirubin-XIIIα with isobutyl chloroformate. Analysis of the circular dichroism spectra of the conjugate in
water and chloroform indicate a conformational preference for the (M)-helical ridge-tile conformation, thus providing the first spectroscopic evidence on the conformation of ditaurobilirubins.
Corresponding author. E-mail: lightner@scs.unr.edu
Received July 5, 2002; accepted July 15, 2002 相似文献
13.
Max Weißenbacher Thomas Sturm Hermann Kalchhauser Christoph Kratky Walter Weissensteiner 《Monatshefte für Chemie / Chemical Monthly》2002,133(7):991-1009
Summary. Novel aminophosphine ligands for enantioselective transition metal catalysts based on different ferroceno cis- and trans-decaline backbones were synthesized and structurally characterized. Their palladium dichloride complexes were tested in the
asymmetric Grignard cross coupling reaction of vinyl bromide and phenylethyl magnesium chloride, but only very low enantioselectivities were
obtained. Steric strain in the aminophosphine ligands causes a severe backbone deformation and in addition leads to a slowed
rotation of the respective dimethylamino group as was detected by variable temperature NMR spectroscopy.
Received January 4, 2002. Accepted January 16, 2002 相似文献
14.
Guido Kickelbick Dieter Rutzinger Thomas Gallauner 《Monatshefte für Chemie / Chemical Monthly》2002,133(8):1157-1164
Summary. Hexadentate ligands were formed by the reaction of primary dimethylaminoethyl- or methoxyethylamines with formaldehyde. The
resulting N, N′, N″-functionalized hexahydro-1,3,5-triazines contain pending amino or ether functionalities which are able to coordinate to
metals in addition to the ring nitrogen atoms. Both ligands were reacted with CuBr, and novel tricopper clusters were isolated
and characterized by X-ray structure analysis. In these compounds a ring nitrogen atom, the pending amino or ether functionality,
and two bridging bromine atoms coordinate each of the copper atoms.
Received January 22, 2002; accepted (revised) March 22, 2002 相似文献
15.
Gregor Radau 《Monatshefte für Chemie / Chemical Monthly》2003,134(7):1033-1036
Summary. The syntheses of dipeptide esters containing a C-terminal L-proline moiety using carbodiimides as coupling reagents strongly depend on the choice of appropriate conditions. Thus, the
use of DCC prefers the formation of the undesirable N,N′-dicyclohexylurea derivative 3 as a consequence of a CO → N-shift in the O-acyl isourea intermediate instead of the desired dipeptide ester 4. In our hands, only DIC was able to yield the desired product exclusively.
E-mail: radau@pharmazie.uni-greifswald.de
Received November 7, 2002; accepted December 4, 2002
Published online May 6, 2003 相似文献
16.
Ramón Serrano Roberto Gaxiola Gabino Ríos Javier Forment Oscar Vicente Roc Ros 《Monatshefte für Chemie / Chemical Monthly》2003,134(11):1445-1464
Summary. We have performed functional genomics of salt stress by overexpression of gene libraries in yeast and selection for salt tolerance. Thirty halotolerance genes were isolated from yeast, Arabidopsis, and sugar beet. The results indicate that Na+ transport (uptake, efflux, and compartmentation), sulfate activation, RNA processing, and protein synthesis are crucial for salt tolerance.Received September 3, 2002; accepted September 16, 2002
Published online June 12, 2003 相似文献
17.
W. Earle Waghorne 《Monatshefte für Chemie / Chemical Monthly》2003,134(5):655-667
Summary. The solubilities of the silver halides in three non-aqueous solvents: methanol, acetonitrile, and dimethylsulfoxide, and
in their aqueous mixtures, are reviewed. Values for the solubility product, K
SO
, the enthalpies of solution, Δ
sol
H
o
, and the equilibrium products for AgX
(i−1)−
i
silver halide complexes, β
i
, are listed and, where possible, compared. The solvent systems provide examples for three types of mixed aqueous solvent
system: aqueous alcohol mixtures and aqueous mixtures with dipolar aprotic solvents that are weakly or strongly basic. The
experimental data are discussed in terms of the solvation of the silver and halide ions in the mixed solvents.
E-mail: Earle.Waghorne@ucd.ie
Received September 30, 2002; accepted October 29, 2002
Published online April 7, 2003
RID="a"
ID="a" Dedicated to Prof. Heinz Gamsj?ger on the occasion of his seventieth birthday 相似文献
18.
Marek Burian Ladislav Omelka Silvie Ondrášová Vlasta Brezová 《Monatshefte für Chemie / Chemical Monthly》2003,134(4):501-508
Summary. Several N-phenyl substituted 1,4- and 1,2-phenylenediamines were oxidized using radicals and 3-chloroperbenzoic acid. EPR spectroscopy confirmed the generation of nitroxide radicals originating from the
oxidation of the bridging -NH-group. No radical products suggesting the simultaneous reaction with the NH2-group were observed. Only in the case of 1,4-phenylenediamine, a low concentration of nitroxide radical H–NO–C6H4–NH2 was obtained. In o-aminodiphenylnitroxide the steric effect of the NH2-group causes a partially asymmetrical spin density distribution in both phenyl rings.
Corresponding author. E-mail: omelka@fch.vutbr.cz
Received September 30, 2002; accepted October 4, 2002 相似文献
19.
Krishna C. Majumdar Uday K. Kundu Swapan K. Samanta Nirmal K. Jana 《Monatshefte für Chemie / Chemical Monthly》2003,134(8):1137-1143
Summary. Two hitherto unreported pyrimidine annelated heterocycles were synthesized from 6-cyclopent-2-enyl-5-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione and 5-cyclopent-2-enyl-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione by reaction with pyridine hydrotribromide or hexamethylenetetramine hydrotribromide. The first one was also obtained by reaction with concentrated sulfuric acid.Received October 28, 2002; accepted October 30, 2002
Published online June 2, 2003 相似文献
20.
Guillaume Laconde Pascal Carato Jacques H. Poupaert Pascal Berthelot Patrick Depreux Jean-Pierre Hénichart 《Monatshefte für Chemie / Chemical Monthly》2003,134(7):1037-1043
Summary. This paper reports an one-pot method for the concomitant alkylation – oxidation (aromatization) of indolines, particularly
effective to get easy access to N-alkyl-6-nitroindoles, which are useful platforms in medicinal chemistry. N-alkyl-6-nitroindoles are obtained in good yield (64–91%) by reaction at room temperature in non-degassed DMF of 6-nitroindoline, an alkyl halide, and NaH as base. The presence of NaH appears to be essential for a high yield conversion.
Corresponding author. E-mail: pdepreux@phare.univ-lille2.fr
Received December 3, 2002; accepted December 9, 2002
Published online May 26, 2003 相似文献