Asymptotic distributions of two “synthetic data” estimators for censored single-index models

The censored single-index model provides a flexible way for modelling the association between a response and a set of predictor variables when the response variable is randomly censored and the link function is unknown. It presents a technique for “dimension reduction” in semiparametric censored regression models and generalizes the existing accelerated failure time models for survival analysis. This paper proposes two methods for estimation of single-index models with randomly censored samples. We first transform the censored data into synthetic data or pseudo-responses unbiasedly, then obtain estimates of the index coefficients by the rOPG or rMAVE procedures of Xia (2006) [1]. Finally, we estimate the unknown nonparametric link function using techniques for univariate censored nonparametric regression. The estimators for the index coefficients are shown to be root-n consistent and asymptotically normal. In addition, the estimator for the unknown regression function is a local linear kernel regression estimator and can be estimated with the same efficiency as the parameters are known. Monte Carlo simulations are conducted to illustrate the proposed methodologies.     

Statistical inference in partially-varying-coefficient single-index model

Consider a varying-coefficient single-index model which consists of two parts: the linear part with varying coefficients and the nonlinear part with a single-index structure, and are hence termed as varying-coefficient single-index models. This model includes many important regression models such as single-index models, partially linear single-index models, varying-coefficient model and varying-coefficient partially linear models as special examples. In this paper, we mainly study estimating problems of the varying-coefficient vector, the nonparametric link function and the unknown parametric vector describing the single-index in the model. A stepwise approach is developed to obtain asymptotic normality estimators of the varying-coefficient vector and the parametric vector, and estimators of the nonparametric link function with a convergence rate. The consistent estimator of the structural error variance is also obtained. In addition, asymptotic pointwise confidence intervals and confidence regions are constructed for the varying coefficients and the parametric vector. The bandwidth selection problem is also considered. A simulation study is conducted to evaluate the proposed methods, and real data analysis is also used to illustrate our methods.     

Censored multiple regression by the method of average derivatives

This paper proposes a technique [termed censored average derivative estimation (CADE)] for studying estimation of the unknown regression function in nonparametric censored regression models with randomly censored samples. The CADE procedure involves three stages: firstly-transform the censored data into synthetic data or pseudo-responses using the inverse probability censoring weighted (IPCW) technique, secondly estimate the average derivatives of the regression function, and finally approximate the unknown regression function by an estimator of univariate regression using techniques for one-dimensional nonparametric censored regression. The CADE provides an easily implemented methodology for modelling the association between the response and a set of predictor variables when data are randomly censored. It also provides a technique for “dimension reduction” in nonparametric censored regression models. The average derivative estimator is shown to be root-n consistent and asymptotically normal. The estimator of the unknown regression function is a local linear kernel regression estimator and is shown to converge at the optimal one-dimensional nonparametric rate. Monte Carlo experiments show that the proposed estimators work quite well.     

Randomly censored partially linear single-index models

This paper proposes a method for estimation of a class of partially linear single-index models with randomly censored samples. The method provides a flexible way for modelling the association between a response and a set of predictor variables when the response variable is randomly censored. It presents a technique for “dimension reduction” in semiparametric censored regression models and generalizes the existing accelerated failure-time models for survival analysis. The estimation procedure involves three stages: first, transform the censored data into synthetic data or pseudo-responses unbiasedly; second, obtain quasi-likelihood estimates of the regression coefficients in both linear and single-index components by an iteratively algorithm; finally, estimate the unknown nonparametric regression function using techniques for univariate censored nonparametric regression. The estimators for the regression coefficients are shown to be jointly root-n consistent and asymptotically normal. In addition, the estimator for the unknown regression function is a local linear kernel regression estimator and can be estimated with the same efficiency as all the parameters are known. Monte Carlo simulations are conducted to illustrate the proposed methodology.     

Empirical likelihood inference in partially linear single-index models for longitudinal data

The empirical likelihood method is especially useful for constructing confidence intervals or regions of parameters of interest. Yet, the technique cannot be directly applied to partially linear single-index models for longitudinal data due to the within-subject correlation. In this paper, a bias-corrected block empirical likelihood (BCBEL) method is suggested to study the models by accounting for the within-subject correlation. BCBEL shares some desired features: unlike any normal approximation based method for confidence region, the estimation of parameters with the iterative algorithm is avoided and a consistent estimator of the asymptotic covariance matrix is not needed. Because of bias correction, the BCBEL ratio is asymptotically chi-squared, and hence it can be directly used to construct confidence regions of the parameters without any extra Monte Carlo approximation that is needed when bias correction is not applied. The proposed method can naturally be applied to deal with pure single-index models and partially linear models for longitudinal data. Some simulation studies are carried out and an example in epidemiology is given for illustration.     

Functional-coefficient partially linear regression model

In this paper, the functional-coefficient partially linear regression (FCPLR) model is proposed by combining nonparametric and functional-coefficient regression (FCR) model. It includes the FCR model and the nonparametric regression (NPR) model as its special cases. It is also a generalization of the partially linear regression (PLR) model obtained by replacing the parameters in the PLR model with some functions of the covariates. The local linear technique and the integrated method are employed to give initial estimators of all functions in the FCPLR model. These initial estimators are asymptotically normal. The initial estimator of the constant part function shares the same bias as the local linear estimator of this function in the univariate nonparametric model, but the variance of the former is bigger than that of the latter. Similarly, initial estimators of every coefficient function share the same bias as the local linear estimates in the univariate FCR model, but the variance of the former is bigger than that of the latter. To decrease the variance of the initial estimates, a one-step back-fitting technique is used to obtain the improved estimators of all functions. The improved estimator of the constant part function has the same asymptotic normality property as the local linear nonparametric regression for univariate data. The improved estimators of the coefficient functions have the same asymptotic normality properties as the local linear estimates in FCR model. The bandwidths and the smoothing variables are selected by a data-driven method. Both simulated and real data examples related to nonlinear time series modeling are used to illustrate the applications of the FCPLR model.     

Estimation for a marginal generalized single-index longitudinal model

In this paper, we suggest an estimating equations based approach to study a general single-index model with a given out-layer link for longitudinal data and treat the classical one as its special case. Within a wide range of bandwidths which is for estimating the inner-layer nonparametric link, the root-n consistency of the estimator of the index can be proved. The estimation efficiency can be achieved even when there is an infinite-dimensional nuisance parameter to be estimated. The performance of the new method is assessed through the comparison with other existing methods and through an application to an epileptic seizure study.     

Generalized partially linear models with missing covariates

In this article we study a semiparametric generalized partially linear model when the covariates are missing at random. We propose combining local linear regression with the local quasilikelihood technique and weighted estimating equation to estimate the parameters and nonparameters when the missing probability is known or unknown. We establish normality of the estimators of the parameter and asymptotic expansion for the estimators of the nonparametric part. We apply the proposed models and methods to a study of the relation between virologic and immunologic responses in AIDS clinical trials, in which virologic response is classified into binary variables. We also give simulation results to illustrate our approach.     

A profile-type smoothed score function for a varying coefficient partially linear model

The varying coefficient partially linear model is considered in this paper. When the plug-in estimators of coefficient functions are used, the resulting smoothing score function becomes biased due to the slow convergence rate of nonparametric estimations. To reduce the bias of the resulting smoothing score function, a profile-type smoothed score function is proposed to draw inferences on the parameters of interest without using the quasi-likelihood framework, the least favorable curve, a higher order kernel or under-smoothing. The resulting profile-type statistic is still asymptotically Chi-squared under some regularity conditions. The results are then used to construct confidence regions for the parameters of interest. A simulation study is carried out to assess the performance of the proposed method and to compare it with the profile least-squares method. A real dataset is analyzed for illustration.     

Single-index quantile regression

Nonparametric quantile regression with multivariate covariates is a difficult estimation problem due to the “curse of dimensionality”. To reduce the dimensionality while still retaining the flexibility of a nonparametric model, we propose modeling the conditional quantile by a single-index function , where a univariate link function g₀(⋅) is applied to a linear combination of covariates , often called the single-index. We introduce a practical algorithm where the unknown link function g₀(⋅) is estimated by local linear quantile regression and the parametric index is estimated through linear quantile regression. Large sample properties of estimators are studied, which facilitate further inference. Both the modeling and estimation approaches are demonstrated by simulation studies and real data applications.     

Partially linear single-index beta regression model and score test

An important model in handling the multivariate data is the partially linear single-index regression model with a very flexible distribution—beta distribution, which is commonly used to model data restricted to some open intervals on the line. In this paper, the score test is extended to the partially linear single-index beta regression model. The penalized likelihood estimation based on P-spline is proposed. Based on the estimation, the score test statistics about varying dispersion parameter is given. Its asymptotical property is investigated. Both simulated examples are used to illustrate our proposed methods.     

Non-parametric kernel regression for multinomial data

This paper presents a kernel smoothing method for multinomial regression. A class of estimators of the regression functions is constructed by minimizing a localized power-divergence measure. These estimators include the bandwidth and a single parameter originating in the power-divergence measure as smoothing parameters. An asymptotic theory for the estimators is developed and the bias-adjusted estimators are obtained. A data-based algorithm for selecting the smoothing parameters is also proposed. Simulation results reveal that the proposed algorithm works efficiently.     

Estimation of location and scale parameters for the Burr XII distribution using generalized order statistics

The minimum variance linear unbiased estimators (MVLUE), the best linear invariant estimators (BLIE) and the maximum likelihood estimators (MLE) based on n-selected generalized order statistics are presented for the parameters of the Burr XII distribution.     

Smooth estimation of survival and density functions for a stationary associated process using Poisson weights

Let {X_n,n≥1} be a sequence of stationary non-negative associated random variables with common marginal density f(x). Here we use the empirical survival function as studied in Bagai and Prakasa Rao (1991) and apply the smoothing technique proposed by Gawronski (1980) (see also Chaubey and Sen, 1996) in proposing a smooth estimator of the density function f and that of the corresponding survival function. Some asymptotic properties of the resulting estimators, similar to those obtained in Chaubey and Sen (1996) for the i.i.d. case, are derived. A simulation study has been carried out to compare the new estimator to the kernel estimator of a density function given in Bagai and Prakasa Rao (1996) and the estimator in Buch-Larsen et al. (2005).     

Statistical inference in a panel data semiparametric regression model with serially correlated errors

We consider a panel data semiparametric partially linear regression model with an unknown vector β of regression coefficients, an unknown nonparametric function g(·) for nonlinear component, and unobservable serially correlated errors. The correlated errors are modeled by a vector autoregressive process which involves a constant intraclass correlation. Applying the pilot estimators of β and g(·), we construct estimators of the autoregressive coefficients, the intraclass correlation and the error variance, and investigate their asymptotic properties. Fitting the error structure results in a new semiparametric two-step estimator of β, which is shown to be asymptotically more efficient than the usual semiparametric least squares estimator in terms of asymptotic covariance matrix. Asymptotic normality of this new estimator is established, and a consistent estimator of its asymptotic covariance matrix is presented. Furthermore, a corresponding estimator of g(·) is also provided. These results can be used to make asymptotically efficient statistical inference. Some simulation studies are conducted to illustrate the finite sample performances of these proposed estimators.     

Variable selection for semiparametric varying coefficient partially linear errors-in-variables models

This paper focuses on the variable selections for semiparametric varying coefficient partially linear models when the covariates in the parametric and nonparametric components are all measured with errors. A bias-corrected variable selection procedure is proposed by combining basis function approximations with shrinkage estimations. With appropriate selection of the tuning parameters, the consistency of the variable selection procedure and the oracle property of the regularized estimators are established. A simulation study and a real data application are undertaken to evaluate the finite sample performance of the proposed method.     

Difference based ridge and Liu type estimators in semiparametric regression models

We consider a difference based ridge regression estimator and a Liu type estimator of the regression parameters in the partial linear semiparametric regression model, y=Xβ+f+ε. Both estimators are analyzed and compared in the sense of mean-squared error. We consider the case of independent errors with equal variance and give conditions under which the proposed estimators are superior to the unbiased difference based estimation technique. We extend the results to account for heteroscedasticity and autocovariance in the error terms. Finally, we illustrate the performance of these estimators with an application to the determinants of electricity consumption in Germany.     

Detection of a change point based on local-likelihood

In this paper, we consider the regression function or its νth derivative in generalized linear models which may have a change/discontinuity point at an unknown location. The location and its jump size are estimated with the local polynomial fits based on one-sided kernel weighted local-likelihood functions. Asymptotic distributions of the proposed estimators of location and jump size are established. The finite-sample performances of the proposed estimators with practical aspects are illustrated by simulated and beetle mortality examples.     

Consistent tuning parameter selection in high dimensional sparse linear regression

An exhaustive search as required for traditional variable selection methods is impractical in high dimensional statistical modeling. Thus, to conduct variable selection, various forms of penalized estimators with good statistical and computational properties, have been proposed during the past two decades. The attractive properties of these shrinkage and selection estimators, however, depend critically on the size of regularization which controls model complexity. In this paper, we consider the problem of consistent tuning parameter selection in high dimensional sparse linear regression where the dimension of the predictor vector is larger than the size of the sample. First, we propose a family of high dimensional Bayesian Information Criteria (HBIC), and then investigate the selection consistency, extending the results of the extended Bayesian Information Criterion (EBIC), in Chen and Chen (2008) to ultra-high dimensional situations. Second, we develop a two-step procedure, the SIS+AENET, to conduct variable selection in p>n situations. The consistency of tuning parameter selection is established under fairly mild technical conditions. Simulation studies are presented to confirm theoretical findings, and an empirical example is given to illustrate the use in the internet advertising data.     

Semiparametric analysis based on weighted estimating equations for transformation models with missing covariates

Missing covariate data are very common in regression analysis. In this paper, the weighted estimating equation method (Qi et al., 2005) [25] is used to extend the so-called unified estimation procedure (Chen et al., 2002) [4] for linear transformation models to the case of missing covariates. The non-missingness probability is estimated nonparametrically by the kernel smoothing technique. Under missing at random, the proposed estimators are shown to be consistent and asymptotically normal, with the asymptotic variance estimated consistently by the usual plug-in method. Moreover, the proposed estimators are more efficient than the weighted estimators with the inverse of true non-missingness probability as weight. Finite sample performance of the estimators is examined via simulation and a real dataset is analyzed to illustrate the proposed methods.