Phytoecdysteroids of plants of the genus Melandrium

The isolation and determination of the structure of the new phytoecdysteroid melandroside A are described; it is viticosterone E 22-O-α-D-galactopyranoside.     

Phytoecdysteroids of plants of the genus Melandrium

The isolation and determination of the structure of the new phytoecdysteroid melandroside A are described; it is viticosterone E 22-O--D-galactopyranoside.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 517–520, July–August, 1991.     

Phytoecdysteroids of plants of theSilene genus and the dynamics of their accumulation

The ecdysteroids of four species of the genusSilene L. have been studied. Six ecdysteroids have been isolated and identified, and the dynamics of the accumulation of the ecdysteroids in relation to the phases of development of the plants have been determined.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 718–723, September–October, 1997.     

Phytoecdysteroids of plants of theSilene genus. XVIII. Tomentesterone fromSilene tomentella

A new ecdysteroid — tomentesterone B — has been isolated from the epigeal part of Silene tomentella. Its structure has been established by chemical transformations and spectral investigations.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 59–61, January–February, 1996. Original article submitted September 4, 1995.     

Phytoecdysteroids of plants of the genusSilene

Ecdysteroids produced by plants of the genusSilene are considered. The discussion covers 17 species of plants, from which 45 ecdysteroids have been isolated. It has been shown that ecdysterone is the most characteristic representative of the biosynthesis of ecdysteroids in theSilene series.     

Phytoecdysteroids of plants of theSilene genus. XIX. The structure of sileneoside G

The phytoecdysteroid sileneoside G has been isolated from the roots ofSilene brahuica Boiss., and its structure has been established on the basis of chemical transformations and spectral, characteristics as ecdysterone 3-O-α-D-galactopyranoside 22-O-α-D-glucopyranoside. Enzymatic hydrolysis yielded ecdysterone and sileneoside D. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (371) 120 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 663–665, September–October, 1998.     

Phytoecdysteroids of plants of the genus Serratula. Ajugasterone C 20,22-monoacetonide from Serratura wolffii

The phytoectysteroids of the epigeal part of the plantSerratula wolffii Andrae have been investigated. The structure of a new ecdysteroid — ajugasterone C 20,22-monoacetonide has been established. Seven known acdysteroids have been isolated and identified.Institute of Biochemistry, Ukrainian Academy of Sciences, Kiev. Institute of Plant Substances, Uzbekistan Republic Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 71–76, January–February, 1992.     

Phytoecdysteroids of plants of the genus Melandrium I. Polypodin B 22-acetate from Melandrium turkestanicum

Known ecdysteroids — ecdysterone, ecdysterone 22-acetate, polypodin B, integristerone A, and sileneosides A and D — and a new phytoecdysteroid — polypodin B 22-acetate — have been found in the epigeal parts of the plantMelandrium turkestanicum (Rg1.) Vved. (family Caryophyllaceae).Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 480–483, July–August, 1990.     

Phytoecdysteroids of plants of the genus Silene. IX. Ecdysterone 22-O-benzoate from Silene scabrifolia

An ecdysteroid which has proved to be ecdysterone 22-O-benzoate has been isolated from the epigeal organs ofSilene scabrifolia Kom.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 77–80, January–February, 1986.     

Phytoecdysteroids of plants of the genus Silene. XVII. Ecdysterone 22,25-di-O-benzoate from Silene scabrifolia

The new phytoecdysteroid ecdysterone 22,25-di-O-benzoate (IV) has been isolated from the epigeal organs ofSilene scabrifolia Kom. The alkaline hydrolysis of (IV) gave ecdysterone 25-O-benzoate and ecdysterone (I). Details of the IR, UV, mass, PMR, and¹³C NMR spectra of compound (IV) are given.Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 363–366, May–June, 1990.     

Phytoecdysteroids of plants of the genus Silene. XIV. Ecdysterone 20-O-benzoate from Silene tatarica

A new ecdysteroid, which has proved to be ecdysterone 20-O-benzoate, has been isolated from the whole plantSilene tatatica (L.) Pers.Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 850–852, November–December, 1987.     

Phytoecdysteroids of plants of the genus Silene. XVII. Ecdysterone 22,25-di-O-benzoate from Silene scabrifolia

The new phytoecdysteroid ecdysterone 22,25-di-O-benzoate (IV) has been isolated from the epigeal organs ofSilene scabrifolia Kom. The alkaline hydrolysis of (IV) gave ecdysterone 25-O-benzoate and ecdysterone (I). Details of the IR, UV, mass, PMR, and¹³C NMR spectra of compound (IV) are given.     

Phytoecdysteroids of plants of the genus Silene. XIV. Ecdysterone 20-O-benzoate from Silene tatarica

A new ecdysteroid, which has proved to be ecdysterone 20-O-benzoate, has been isolated from the whole plantSilene tatatica (L.) Pers.     

Phytoecdysteroids of plants of the genus Silene. XVI. Viticosterone E 22-O-benzoate from Silene wallichiana

A new phytoecdysteroid, viticosterone E 22-O-benzoate (I), C₃₆H₅₀O₀, mp 147–149°C (methanol-water), [] _D ²⁰ +63.2° (methanol), has been isolated from the epigeal organs ofSilene wallichiana Klotzsch. The alkaline hydrolysis of (I) led to viticosterone E and benzoic acid. The acetylation of (I) gave the 2,3-diacetate (II), C₄₀H₅₄O₁₁, mp 152–153°C (methanol-water), [] _D ²⁰ +65.5° (methanol). Details of the IR, PMR, and mass spectra of (I) and (II) are given.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 546–549, July–August, 1988.     

Phytoecdysteroids of plants of the genus Silene. XVIII. 2-Deoxyecdysterone 20,22-monoacetonide from Silene brahuica

In addition to the known 2-deoxy--ecdysone, 2-deoxyecdysterone, 2-deoxy--ecdysone-22-O-acetate, ecdysterone, integristerone A, and sileneoside A, B, and C, the new ecdysteroid 2-deoxyecdysterone 20,20-monoacetonide has been isolated from the roots of the plantSilene brahuica Boiss.Institute of Chemistry of Plant Substances Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 241–244, March–April, 1991.     

Phytoecdysteroids of plants of the genusSilene

Ecdysteroids produced by plants of the genusSilene are considered. The discussion covers 17 species of plants, from which 45 ecdysteroids have been isolated. It has been shown that ecdysterone is the most characteristic representative of the biosynthesis of ecdysteroids in theSilene series.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 627–635, September–October, 1993.     

Phytoecdysteroids of plants of the genus Silene. XV. 2-Deoxy-α-ecdysone 22-O-benzoate from Silene wallichiana

A new phytoecdysteroid, 2-deoxy-α-ecdysone 22-O-benzoate, has been isolated from the epigeal organs ofSilene wallichiana Klotzch.     

Phytoecdysteroids of plants of the genus Silene. XI. 2-Deoxy-α-ecdysone 3-acetate from Silene scabrifolia

From the epigeal organs ofSilene scabrifolia Kom. has been isolated the new phytoecdysteroid 2-deoxy-α-ecdysone 3-acetate (II) (0.0011%), C₂₉H₄₆O₆, mp 216–218°, [α] _D ²⁰ +131.9° (methanol). The enzymatic hydrolysis of (II) led to 2-deoxy-α-ecdysone (I). The acetylation of 2-deoxy-α-ecdysone (I) yielded (II) and the 22-monoacetate (III) and 3,22-diacetate (IV) of 2-deoxy-α-ecdysone, which have been described previously. Details of the IR, UV, CD, mass, and NMR spectra are given for (I) and of the IR, mass, and NMR spectra for (III).     

Phytoecdysteroids of plants of the genusSilene XIV. Brahuisterone fromSilene brahuica

A new ecdysteroid with the composition C₂₇H₄₄O₆ which has been called brahuisterone has been isolated from the epigeal part of the plantSilene brahuica Boiss. Its chemical and complete spatial structures have been established by spectral studies and the x-ray structural method (diffractometer, Cu-K_α radiations, 996 reflections, direct method, R=0.119).