一个肿瘤生长自由边界问题解的整体存在性和唯一性

该文研究一个反应扩散方程组的自由边界问题,它来源于描述抑制物作用下无坏死核肿瘤生长的数学模型.作者运用抛物型方程的L_p理论和压缩映照原理,证明了这个问题局部解的存在唯一性,然后用延拓方法得到了整体解的存在唯一性.     

非局部的退化抛物型方程组的解的爆破和整体存在性

该文采用弱上下解方法以及正则化的技巧,研究了一类非局部的退化的抛物型方程组的解的爆破和整体存在性,给出了方程组的解的爆破指标p_c=(p₁+p₂)(q₁+q₂)-mn,证得当p_c<0时,对任意的初值,方程组的解整体存在;当p_c>0时,对充分大的初值,解在有限时刻爆破,对充分小的初值,解整体存在;当p_c=0时,若区域充分小,则方程组存在非负整体解,若区域包含了一个充分大的球, 则解在有限时刻爆破.     

奇异介子光生反应的低能QCD Lagrange量描述

从低能QCD Lagrange量出发, 利用重子夸克结构的［SU_SF(6)O(3)]_sym. SU_c(3)波函数,研究了在核子上的奇异介子光生反应. 计算了γ+p→K ⁺+Λ反应的总截面、微分截面和p-极化. 结果表明: 与传统的唯象的强子理论相比, 仅有一个自由参数(即强相互作用耦合常数)的QCD理论成功地描述了反应过程, 很好地解释了实验结果.     

分形测度的比较

讨论s维测度与g-测度之间的关系, 其中g是一个等价于幂函数t^s的纲函数(0≤s≤d). 当s=d时, 证明了关系式 和在R^d上成立, 其中的常数c₁, c₂和c₃由下式确定: H^g, C^g和P^g分别为R^d上的g-Hausdorff, 中心g-Hausdorff和g-填充测度. 当0<s<d时, 通过例子表明上述结论不成立. 然而存在s-集FÌR^d, 使得 其中常数c₁, c₂和c₃不仅依赖于g和s, 而且还依赖于F. 并且给出了判断一个s-集具有上述性质的条件.     

一个肿瘤生长自由边界问题的研究

本文研究一个描述肿瘤生长的自由边界问题.这个自由边界问题是对Byrne和Chaplain相应肿瘤生长模型的一个改进,研究了该问题解当t→∞时的渐近状况,证明了未血管化的肿瘤体积不会无限制地增大,它或者趋于消失,或者趋于一个休眠态,依营养物浓度的大小和抑制物浓度的大小而定.     

一个肿瘤生长自由边界问题的研究

本文研究一个描述肿瘤生长的自由边界问题.这个自由边界问题是对Byrne和Chaplain相应肿瘤生长模型的一个改进,研究了该问题解当t→∞时的渐近状况,证明了未血管化的肿瘤体积不会无限制地增大,它或者趋于消失,或者趋于一个休眠态,依营养物浓度的大小和抑制物浓度的大小而定.     

共振情形下具有不对称非线性项Liénard 方程无界解和周期解的共存性

本文研究一类平面映射 无界轨道的存在性, 其中n是正整数, c是常数, μ (θ)是2π周期函数, 证明了当 c>0, μ (θ)≠0时, 对充分大的ρ, 该映射的轨道正向趋于无穷; 当c<0, μ (θ)≠0时, 对充分大的ρ, 该映射的轨道负向趋于无穷. 应用这个结论, 在函数F(x)(∫₀^xf (s)ds)和f(x)存在有限极限的条件下, 证明了 方程x''''+f(x)x''+ax⁺-bx^-+f(x)=p(t)存在无界解. 同时, 还得到了该方程周期解的存在性.     

Fe-N软磁薄膜的结构和性能

用RF溅射制备厚度为200 nm的Fe-N薄膜在250℃, 12000 A/m磁场下真空热处理后，当N含量在5%～7%(原子百分数)范围内形成α′+α″相时，4πM_S可达2.4 T, H_c＜80 A/m, 2～10 MHz下高频相对导磁率μ_r=1500，可满足针对10 Gb/in2存储密度的GMR/感应式复合读写磁头中写入磁头的需要. Fe-N系薄膜中α′相的形成机理和点阵常数与块状试样按Bain机理形成的α′相有明显的差别，得到了薄膜中α′相的a,c与Cα′_N之间的线性关系式.     

沿LiNbO3 y方向的准纵波及其超声非线性系数

本文给出了沿LiNbO₃ y方向的准纵波的非线性运动方程及其解.由于LiNbO₃晶体的二阶弹性常数c₁₄比c₁₁和 c₄₄小很多,沿y方向的准纵波非常接近纯模式,为用超声二次谐波发生技术测量晶体的超声非线性系数和三阶弹性常数提供了一个新的传播模式.对于LiNbO₃(或其它具有3m对称的晶体)从这个传播模式的超声非线性系数,可以确定一个包括c₂₂₂,c₂₄₄,c₁₁₄,c₁₂₄和c₄₄₄5个三阶弹性常数的组合.在准静态近似下,求得了与这个传播模式有关的二阶和三阶弹性常数与压电耦合的关系.用超声二次谐波发生技术测量了该模式的超声非线性系数,并求得了相应的三阶弹性常数的组合.实验和利用其他作者发表的数据计算的结果相符合.     

FeCr2-x GaxS4的磁性与巨磁电阻效应

研究了没有双交换作用的FeCr^2-x Ga_xS₄材料的磁性以及CMR效应.实验指出：Ga对Cr的替代破坏了Cr亚晶格自旋的相互作用,使体系FM性增强从而导致T_c提高,但PM到FM相变的幅度随掺杂逐渐降低.ESR给出的微观磁性指出Fe,Cr亚晶格自旋在温度低于T_c时各自是FM排列,而两者之间是AFM排列,以致对未掺杂样品,体系的宏观磁矩M相互抵消,掺杂样品在T_c将出现固有FM性. Ga掺杂使发生MR的峰值温度提高,但MR值降低.     

A Hopf Bifurcation in a Generalized Mckean Type of Free Boundary Problem Satisfying the Dirichlet Boundary Condition

In this paper, we consider the free boundary problem satisfying the Dirichlet boundary condition. This problem is derived from the reaction diffusion equations with the generalized McKean reaction dynamics. We shall show a Hopf bifurcation occurs at some critical point τ when the stationary solution (v^⋅ (x), s^⋅) satisfies 1/3 < s^⋅ < 1.     

Existence of a stationary solution for the modified Ward–King tumor growth model

This paper studies existence of a stationary solution to a tumor growth model proposed by Ward and King in 1997 and 1998, with biologically reasonable modifications. Mathematical formulation of this problem is a two-point free boundary problem of a system of ordinary differential equations, one of which is singular at boundary points. By using the Schauder fixed point theorem we prove existence of a solution for this problem.     

Delay nonlinear boundary conditions as limit of reactions concentrating in the boundary

In this work, we are interested in the dynamic behavior of a parabolic problem with nonlinear boundary conditions and delay in the boundary. We construct a reaction–diffusion problem with delay in the interior, where the reaction term is concentrated in a neighborhood of the boundary and this neighborhood shrinks to boundary, as a parameter ? goes to zero. We analyze the limit of the solutions of this concentrated problem and prove that these solutions converge in certain continuous function spaces to the unique solution of the parabolic problem with delay in the boundary. This convergence result allows us to approximate the solution of equations with delay acting on the boundary by solutions of equations with delay acting in the interior and it may contribute to analyze the dynamic behavior of delay equations when the delay is at the boundary.     

Bifurcation analysis of amathematical model for the growth of solid tumors in the presence of external inhibitors

We study bifurcations from radial solution of a free boundary problem modeling the dormant state of nonnecrotic solid tumors in the presence of external inhibitors. This problem consists in three linear elliptic equations with two Dirichlet and one Neumann boundary conditions and a fourth boundary condition coupling surface tension effects on free boundary. In this paper, surface tension coefficient γ plays the role of bifurcation parameter. We prove that in certain situations there exists a positive null point sequence for γ where bifurcation occurs from radial solution, while in the other situations, either bifurcation occurs at only finite many points of γ or even it does not occur for any γ > 0. Copyright © 2014 John Wiley & Sons, Ltd.     

Numerical solutions for some coupled systems of nonlinear boundary value problems

Summary In the well-known Volterra-Lotka model concerning two competing species with diffusion, the densities of the species are governed by a coupled system of reaction diffusion equations. The aim of this paper is to present an iterative scheme for the steady state solutions of a finite difference system which corresponds to the coupled nonlinear boundary value problems. This iterative scheme is based on the method of upper-lower solutions which leads to two monotone sequences from some uncoupled linear systems. It is shown that each of the two sequences converges to a nontrivial solution of the discrete equations. The model under consideration may have one, two or three nonzero solutions and each of these solutions can be computed by a suitable choice of initial iteration. Numerical results are given for these solutions under both the Dirichlet boundary condition and the mixed type boundary condition.     

Analysis of an elliptic-parabolic free boundary problem modelling the growth of non-necrotic tumor cord

We study a free boundary problem modelling the growth of a tumor cord in which tumor cells live around and receive nutrient from a central blood vessel. The evolution of the tumor cord surface is governed by Darcy's law together with a surface tension equation. The concentration of nutrient in the tumor cord satisfies a reaction-diffusion equation. In this paper we first establish a well-posedness result for this free boundary problem in some Sobolev-Besov spaces with low regularity by using the analytic semigroup theory. We next study asymptotic stability of the unique radially symmetric stationary solution. By making delicate spectrum analysis for the linearized problem, we prove that this stationary solution is locally asymptotically stable provided that the constant c representing the ratio between the diffusion time of nutrient and the birth time of new cells is sufficiently small.     

Global Existence for a Parabolic-hyperbolic Free Boundary Problem Modelling Tumor Growth

In this paper we study a free boundary problem modelling tumor growth, proposed by A. Friedman in 2004. This free boundary problem involves a nonlinear second-order parabolic equation describing the diffusion of nutrient in the tumor, and three nonlinear first-order hyperbolic equations describing the evolution of proliferative cells, quiescent cells and dead cells, respectively. By applying Lp theory of parabolic equations, the characteristic theory of hyperbolic equations, and the Banach fixed point theorem, we prove that this problem has a unique global classical solution.     

Bifurcation for a free boundary problem modeling the growth of a tumor with a necrotic core

We consider a free boundary problem for a system of partial differential equations, which arises in a model of tumor growth with a necrotic core. For any positive numbers ρ<R, there exists a radially symmetric stationary solution with tumor boundary r=R and necrotic core boundary r=ρ. The system depends on a positive parameter μ, which describes the tumor aggressiveness. There also exists a sequence of values μ₂<μ₃<? for which branches of symmetry-breaking stationary solutions bifurcate from the radially symmetric solution branch.     

Global well-posedness for a drug transport model in tumor multicell spheroids

In this paper we study global existence of solutions of a mathematical model for drug transport in tumor multicell spheroids. The model is a free boundary problem of a system of partial differential equations. It contains one nonlinear first-order equation describing the distribution of live tumor cells, and two nonlinear reaction diffusion equations describing the evolution of nutrient concentration and drug concentration, respectively. By using the method of characteristics for first-order equations, the $L^p$-theory for parabolic equations, the Banach fixed point theorem and the extension method, we prove that this problem has a unique global solution.