共查询到20条相似文献,搜索用时 15 毫秒
1.
N-Substituted pyrroles were synthesized under neat conditions by the reaction of aromatic amines with 2, 5-dimethoxytetrahydrofuran in excellent yields. 相似文献
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Barahman Movassagh Mohammad Soleiman-Beigi 《Monatshefte für Chemie / Chemical Monthly》2008,139(2):137-140
Summary. A simple and efficient procedure was developed for the synthesis of S-alkyl (aryl) thiocarbamates under solvent-free conditions without the use of a catalyst. The significant features of this
protocol are (a) operational simplicity, (b) mild reaction conditions, (c) short reaction times, (d) solvent-free conditions,
and (e) high product yields. 相似文献
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A one-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles with two identical substituents directly from the reaction of nitriles and hydroxylamine hydrochloride in the presence of potassium fluoride as catalyst and solid support under solvent-free condition is described. Moreover, the formation of products has been discussed, and a plausible mechanism has been presented. Simplicity of the process, workup in aqueous media, and excellent yields are some advantages of this method. 相似文献
5.
A versatile and efficient route to 3-amino-1-aryl-9H-fluorene-2,4-dicarbonitrile via multicomponent reactions of 1-indanone, aromatic aldehydes, and malononitrile under solvent-free conditions using NaOH as the catalyst is described. This method provides several advantages over alternative procedures such as mild, solvent-free conditions at ambient temperature and direct isolation of the products in good yields. 相似文献
6.
Martín J. Riveira 《合成通讯》2013,43(2):208-220
Ethylenediammonium diacetate readily catalyzes the Knoevenagel-type condensation between 1,3-dicarbonyl substrates and α,β-unsaturated aldehydes at room temperature under solvent-free conditions. This rapid, efficient, and convenient one-pot approach to the synthesis of 2H-pyrans stands as a significant advance over previously reported protocols. This environmentally friendly methodology has been successfully applied to the synthesis of biologically active natural products of interest zanthosimuline, N-methylflindersine, and ferprenin. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications ® to view the free supplemental file. 相似文献
7.
Javad Azizian Khadijeh Yadollahzadeh Hasan Tahermansouri Davood Chobfrosh Khoei Akram Sadat Delbari 《合成通讯》2013,43(14):2110-2120
Urea polyfunctional derivatives were successfully synthesized via a one-pot, five-component nucleophilic addition/Ugi reaction sequence. Simplicity, solvent-free conditions, and good yields of products are advantages of this method. 相似文献
8.
Ghasem Rezanejade Bardajee Hamid Samareh Afsari Seyediraj Sadraei Seyedehmaryamdokht Taimoory 《Phosphorus, sulfur, and silicon and the related elements》2013,188(7):871-878
Abstract An efficient, versatile, and environmentally benign method for the synthesis of dithiocarbamates under solvent-free conditions is reported. The Michael addition of electron-deficient alkenes with alkyl or aryl amines and CS2 in the presence of OH?/silica in a one-pot three-component reaction protocol gave the corresponding dithiocarbamates in good to excellent yields. This method is suitable for a wide range of amines and a variety of Michael acceptors in solvent-free conditions. The results of the present work show the desired products in excellent yields. 相似文献
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Nora M. Rateb 《合成通讯》2013,43(15):2789-2794
An improved Claisen–Schmidt condensation reaction of methyl ketones and aromatic aldehydes can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions. 相似文献
11.
An efficient method for the synthesis of a series of ferrocenylcyclohexenones via tandem Michael–aldol reaction of ferrocenyl-substituted chalcones with dibenzyl ketone under solvent-free conditions is described. It was found that the factors including the electronic nature of chalcone, basicity of the base, reaction time, and temperature have effects on the formation of the ferrocenylcyclohexenones. 相似文献
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A mild and practically convenient one-pot procedure for the Mannich reaction via condensation of amines, aldehydes and malonates, β-ketoesters, or β-dicarbonyl compounds has been carried out without using any organic solvent, metallic catalyst, or Lewis acids or bases at room temperature. The present protocol offers several advantages, such as goods yields, simple procedure with easy workup, and the absence of any volatile, hazardous organic solvents and metallic catalyst. 相似文献
14.
An efficient and convenient method for the preparation of 2,4-diamino-6-arylpyrimidine-5-carbonitrile derivatives by the one-pot reaction of aromatic aldehydes, malononitrile, and guanidine carbonate, in the presence of sodium hydroxide under solvent-free conditions, was reported. This method has the advantages of excellent yields, mild reaction conditions, easy work up, and environmental friendliness over the existing procedures. 相似文献
15.
A green, efficient method for the synthesis of various 2-aryl-benzimidazoles in the presence of hypervalent iodine as the oxidant at room temperature under solvent-free conditions is reported. The salient features of this method include mild conditions, short reaction times (3–5 min), excellent yields, and simple procedure. 相似文献
16.
Surya K. De 《合成通讯》2013,43(16):2768-2774
Paal–Knorr condensation of 2,5-hexadione with primary amines in the presence of a catalytic amount of praseodymium(III) trifluoromethanesulfonate under solvent-free conditions has been accomplished with an excellent yield. This method is a very easy, rapid, and high-yielding reaction for the synthesis of N-substituted pyrrole derivatives. 相似文献
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Straightforward procedures for the fast and efficient synthesis of differently substituted barbituric acid–based chalconoids under solvent-free conditions were developed. 相似文献
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H. R. Prakash Naik H. S. Bhojya Naik T. R. Ravikumar Naik D. S. Lamani T. Aravinda 《Phosphorus, sulfur, and silicon and the related elements》2013,188(3):663-667
An efficient synthesis of substituted condensed quinolino-quinolines has been achieved in a one-pot reaction from 2-hydroxy/mercapto/seleno-4-methylquinoline and 2-mercapto/seleno-3-formyl quinolines using anhydrous ammonium hydroxide as the reductant by microwave irradiation under solvent-free conditions. 相似文献