The structure of majdine, pseudokopsinine, and vinervinine

Summary Three new bases have been isolated fromVinca erecta andV. major. The structures of majdine, pseudokopsinine, and vinervinine have been established.Khimiya Prirodnykh Soedinenii, Vol. 3, No. 5, pp. 310–315, 1967     

Stereospecific synthesis of (+)-oxybiotin from D-xylose. Preparation of the final chiral (+)-oxybiotin precursor

A stereospecific synthesis of 2(S)-carbomethoxy-butyl-3(R), 4(S)-diacetamido-tetrahydrofurane (11), the final chiral precursor in a new synthesis of (+)-oxybiotin has been achieved from 2, 5-anhydro-D-xylose derivative1.     

Triterpenoids from Rhododendron caucasicum and Rh. ledebourii gas-liquid chromatography of rhododendron extracts

Conclusions FromGentiana olgae have been isolated gentiananine, gentianadine, and the new base gentianaine C₆H₇O₃N. The structural formula for the latter has been given.G. caucasica contains gentianine and gentiananine; andG. kaufmanniana contains gentianine, gentianaine, and gentiananine; gentianaine has been found in the mother liquors fromG. turkestanorum andG. olivieri.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 1, pp. 32–36, 1969     

The structures of vepridimerines A-D,four new dimeric prenylated quinolone alkaloids from Vepris lousii and Oricia renieri (Rutaceae)

Four new isomeric dimeric prenylated quinolone alkaloids, vepridimerines A-D, have been isolated from the bark of Vepris louisii and Oricia renieri (Rutaceae) and have been assigned structures (2)–(5) respectively on the basis of spectroscopic evidence, in particular¹H and¹³C n.m.r. data.     

Leuconine — A new alkaloid from Aconitum leucostomum and A. septentrionale

A new alkaloid — leuconine — has been isolated from the epigeal parts ofAconitum leucostomum andA. septentrionale, and its structure has been established on the basis of spectral characteristics. Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 538–540, September–October, 1992.     

A study of the alkaloids ofCodonopsis clematidea

Conclusions From the epigeal part ofCodonopsis clematidea, the new alkaloid codonopsine has been isolated; its most probable structure is 1,4-dihydroxy-1,3-dimethyl-5-veratrylpyrrolidine.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 1, pp. 30–32, 1969     

Synthesis of Benzofuro-and Benzothieno-Phenanthridones by Twofold Photochemical Dehydrocyclization Reaction

Four new N-(p-chlorophenyl) carboxamides 1–4 of 9-phenanthrene-, 5-naphtho[2, 1-b] furan-, and 5-naphtho-and 4-naphtho[2, 1-b] thiophenecarboxylic acids have been synthesized. All carboxanilides were exposed to UV oxidative irradiation in methanolic solution. In the case of 2 and 3 corresponding benzo[d]-furo[3, 2-f] phenanthridin-10 (9H)-one 5 and benzo [d]-thieno[3, 2-f] phenanthridin-10 (9H)-one 6 are isolated.     

The structure of erivanin

Conclusions FromArtemisia frangrans Willd. var. erivanica Bess. a new sesquiterpene lactone, erivanin, has been isolated. Structure I has been proposed as the most probable for it.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 4, pp. 239–241, 1969     

A study of the alkaloids ofSaussurea salsa andS. elegans

Conclusions 1. In the extraction ofS. salsa andS. elegans, the condensation of the neutral substances with ammonia takes place with the formation of products of a basic nature.2. FromS. elegans a new alkaloid elegantine C₂₃H₂₉O₅N has been obtained the saponification of which has given tyramine and a sesquiterpene lactone.Khimiya Prirodnykh Soedinenii, Vol. 4, No. 6, pp. 367–370, 1968     

A new Method for the Synthesis of 5-Benzyl-1-(2-Hydroxyethoxy Methyl)Uracil (Bau), A Potent Uridine Phosphorylase Inhibitor,And Its N3-And N1, N3, -Substituted Analogs

A new methodology for the synthesis of 5-benzyl-l-(2-hydroxyethoxymethyl)uracil (BAU)² (1), a potent uridine phosphorylase inhibitor, has been developed. The coupling of bis(trimethylsilyl) derivative of 5-benzyl uracil with 2-acetoxyethoxymethyl bromide, followed by removal of the protecting 0-acetyl group, afforded compound 1. However, treatment of the silyl derivatives of 5-benzyluracil with 2-acetoxyethyl acetoxymethyl ether in the presence of stannic chloride as catalyst, followed by deblocking, gave three products,1, 2 and 3, respectively.     

Phytoecdysteroids of Rhaponticum carthamoides. II. Rhapisterone B

A new ecdysteroid (rhapisterone B) has been isolated from the seeds ofRhaponticum cathamoides (Willd.) Iljin. (familyCompositae). It has been shown that it is 2β, 3β, 11α, 14α, 20R, 24ξ-hexahydroxy-5β-cholest-7-en-6-one. Institute of the Chemistry of Plant Substances, Uzbek Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 806–808, November–December, 1991.     

Polysaccharides ofPanax ginseng

Summary Triterpene substances hzve been found in aqueous extracts of the roots ofMeristotropis triphylla Fisch. et Mey. on acid hydrolysis in methanol. Two new triterpene acids, isomeristotropic and triphyllic acids, have been isolated and characterized.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 5, pp. 311–315, 1965     

Glycosides of Erysimum

Summary The cardenolides of six species ofErysimum and ofSyrenia siliculosa have been studied. The cardiac glycosides erysimin and erysimoside have been found inE. altaicum, E. marschallianum, E. nuratensae, andS. siliculosa. In addition to these glycosides,E. diffusum has yielded desglucocheirotoxin, canescein, and a new cardenolide, erydiffuside,E. violascens has yielded gypsobioside, andE. cuspidatum has yielded a new glycoside cuspidoside.Khimiya Prirodnykh Soedinenii, Vol. 3, No. 2, pp. 173–178, 1967     

A new flavone glycoside fromAntitoxicum funebrae

Summary A new flavonoid, antoside, which is the 3(7)-glucoside-7(3)-rhamnoside of quercetin has been isolated fromAntitoxicum funebrae.Khimiya Prirodnykh Soedinenii, Vol. 2, No. 5, pp. 319–321, 1966     

Secondary metabolites of Ulocladium chartarum. Ulocladols A and B — New phytotoxins of terpenoid nature

Ulocladols A and B — new exometabolites having a mixed sesquiterpenoid-polyketide nature that are structurally close to the host-specific toxins ofAlternaria citri — have been isolated from the deuteromyceteUlocladium chartarum. Both substances inhibit the growth of cotton seeds. All-Union Scientific Research Institute of Phytopathology, Moscow Province, Golitsyno. M. V. Lomonosov Moscow State University. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 642–648, September–October, 1991.     

Alkaloids of Aconitum sajanense II. Structure of dehydroacosanine

The new alkaloid dehydroacosanine has been isolated from the roots ofAconitum sajanense Kumin, and its structure has been established by spectral and chemical methods.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 531–534, September–October, 1992.     

The Reaction of Phosphonium Ylids with o-Quinones and Triketones

Abstract

The reaction of 1,2-benzo [a] phenazine-8, 9-dione 1 and/or 1,2,3-indantrione 2, with phosphonium ylides has been studied. When 1 was reacted with two molar amounts of methoxy-(3a) and/or ethoxycarbonylmethylenetriphenylphosphorane (3b), in THF, at the reflux temp, for 3 hrs, dimethyl (4a) and/or diethyl 1,2-dihydrobenzo a furo [3,2-h] phenazine-1,2-dicarboxylate (4b), along with triphenylphosphine oxide and triphenylphosphine were obtained. On the other hand, reaction of equimolar amounts of ylides 3 with the red trione 2 in THF at room temp., afforded colourless crys tals of 2′,4′-dihydroxyspiro [indan-2,3′ (2′H)-indeno [1,2-b] pyran]-1,3,5′(4′H)-trione diacetate (5a) or dipropionate (5b), together with triphenylphosphine oxide. Formation of 6-membered dihydro aromatic ring like 5, is considered as a new reaction of phos phoranes. The structure of the new compounds 4 and 5 was confirmed and the reaction mechanisms are discussed.