共查询到20条相似文献,搜索用时 984 毫秒
1.
The synthesis and characterization of ferrocene (Fc) derivatives 4-[2,5-diferrocenyl-4-(4-pyridyl)imidazolidin-1-ylmethyl]pyridine (1), ferrocenylmethylenepyridin-3-ylmethylamine (2), N,N'-bis(ferrocenylmethylene)-2,4,6-trimethylbenzene-1,3-diamine (3), and 6-ferrocenyl-5,6-dihydro[4,5]imidazo[1,2-c]quinazoline (4) have been described. Structures of 1, 2, and 4 have been determined by single-crystal X-ray diffraction analyses. At 25 °C, 1-3 are nonfluorescent, while 4 displays moderate fluorescence and chromogenic, fluorogenic, and electrochemical sensing selectively toward Hg(2+) and Pb(2+) ions. Association constants (K(a)) for Hg(2+) and Pb(2+) have been determined by the Benesi-Hildebrand method. Job's plot analysis supported 1:1 and 1:2 stoichiometries for Hg(2+) and Pb(2+) ions. Cyclic voltammograms of 1-4 exhibited reversible waves corresponding to a ferrocene/ferrocenium couple. The wave associated with 4 (+0.0263 V) exhibited positive (ΔE(pa) = 0.136 V) and negative (ΔE(pa) = 0.025 V) shifts in the presence of Hg(2+) and Pb(2+) ions, respectively. The mode of interaction between metal ions and 4 has been supported by (1)H NMR spectroscopy and mass spectrometry studies and verified by theoretical studies. It presents the first report dealing with ferrocene-substituted quinazoline as a multichannel chemosensor for Hg(2+)/Pb(2+) ions. 相似文献
2.
The synthesis, dual fluorescence, and fluoroionophoric behavior of two donor-sigma spacer-acceptor (D-s-A) compounds, trans-4-(N,N-bis(2-pyridyl)amino)methylstilbene (1H) and trans-4-(N,N-bis(2-pyridyl)amino)methyl-4'-cyanostilbene (1CN), are reported and compared to that of trans-4-(N,N-bis(2-pyridyl)amino)methyl-4'-(N,N-dimethylamino)stilbene (1DPA). To gain insights into the dual fluorescence properties for 1H and 1CN in polar but not in nonpolar solvents, model compounds resulting from a replacement of the stilbene group by alkyl (2R) or xylyl (2X) groups or from a replacement of the dipyridylamino (dpa) group by dianisoleamino (3AA), diethylamino (3EE), methylanilino (3MP), or diphenylamino (3PP) groups also have been investigated. In addition to 1H and 1CN, all four compounds of 3 display dual fluorescence. The locally excited (LE) fluorescence mainly results from the stilbene group and the ICT fluorescence from the through-bond interactions between the amino donor and the stilbene acceptors. In the presence of transition metal ions such as Zn(II), Ni(II), Cu(II), and Cd(II), the ICT processes are switched from dpa (D) --> stilbene (A) in 1H and 1CN to stilbene (D) --> dpa/metal ion (A) in their complexes. Whereas the ICT states for the complexes are generally nonfluorescent, an exception was found for the case of 1H/Zn(II). As a result, substituent-dependent fluoroionophoric behavior has been demonstrated by 1H, 1CN, and 1DPA in response to Zn(II). 相似文献
3.
Zheng S Barlow S Risko C Kinnibrugh TL Khrustalev VN Jones SC Antipin MY Tucker NM Timofeeva TV Coropceanu V Brédas JL Marder SR 《Journal of the American Chemical Society》2006,128(6):1812-1817
We report the first structural data for bis(diarylamine) "bipolarons": we have isolated and crystallographically characterized salts of the dications obtained by two-electron oxidation of E-4,4'-bis[di(p-anisyl)amino]stilbene and E,E-2,5-bis{4-[di(p-anisyl)amino]styryl}-3,4-di(n-butoxy)thiophene, [1](2+) and [2](2+) respectively. ESR, NMR, and magnetometry suggest both species have singlet ground states. X-ray structures, together with (1)H NMR coupling constants for [2](2+), indicate geometries in which the bond lengths are shifted toward a quinoidal pattern relative to that in the neutral species, but not to a fully quinoidal extent. In particular, the bond-length alternations across the vinylene bridging groups approach zero. DFT calculations with closed-shell singlet configurations reproduce the observed structures well. Our results indicate that singlet species for which one might expect quinoidal geometries (with differences of ca. 0.1 A between formally single and double bonds) on the basis of a limiting valence-bond representation of the structure can, in fact, show structures with significantly different patterns of bond lengths. 相似文献
4.
Chadlaoui M Abarca B Ballesteros R Arellano CR Aguilar J Aucejo R García-España E 《The Journal of organic chemistry》2006,71(24):9030-9034
The characteristics as a chemosensor of the compound 3-methyl-6,8-di(2-pyridyl)-[1,2,3]triazolo[5',1':6,1]pyrido[2,3-]pyrimidine (1) have been analyzed. Interaction with Cu(2+) produces a quenching of the fluorescence, while interaction with Zn(2+) leads to a quenching of the fluorescence followed by a bathochromic shift. The crystal structure of the Zn(1)(H(2)O)(3)(ClO(4))(2) x H(2)O complex shows the coordination of Zn(2+) through the terpyridine moiety. The octahedral site is completed by three water molecules. Interactions of the Zn(2+) complex with the anions sulfate, nitrate, nitrite, and dihydrogenphosphate in ethanol produce hypsochromic shifts and restoration of the fluorescence whose magnitude depends on the anion involved. The maximum interaction is observed for H(2)PO(4)(-). Interactions of the Zn(2+) complex with the amino acids l-aspartate and l-glutamate have also been explored showing a higher interaction with l-aspartate. 相似文献
5.
Coe BJ Harries JL Harris JA Brunschwig BS Horton PN Hursthouse MB 《Inorganic chemistry》2006,45(26):11019-11029
Four new complex salts trans[RuIICl(pdma)2LA][PF6]n [pdma = 1,2-phenylenebis(dimethylarsine); LA = 1,4-bis[E-2-(4-pyridyl)ethenyl]benzene (bpvb), n = 1, 1; LA = N-methyl-1,4-bis(E-2-(4-pyridyl)ethenyl)benzene (Mebpvb+), n = 2, 2; LA = N-phenyl-1,4-bis(E-2-(4-pyridyl)ethenyl)benzene (Phbpvb+), n = 2, 3; LA = N-(2-pyrimidyl)-1,4-bis(E-2-(4-pyridyl)ethenyl)benzene (Pymbpvb+), n = 2, 4] have been prepared. The electronic absorption spectra of 1-4 display intense, visible metal-to-ligand charge-transfer (MLCT) bands, with lambda(max) values in the range 432-474 nm in acetonitrile. Intense intraligand charge-transfer (ILCT) bands due to LA are also observed, with lambda(max) values in the range 350-416 nm. Cyclic voltammetric studies in acetonitrile reveal reversible RuIII/II waves with E(1/2) values of ca. 1.05 V vs Ag/AgCl, together with LA-based reduction processes that are irreversible with the exception of 1. Salts 1-4 have been investigated by using Stark (electroabsorption) spectroscopy in butyronitrile glasses at 77 K. These studies have afforded dipole moment changes, Deltamu12, for the MLCT and ILCT transitions which have been used to calculate molecular static first hyperpolarizabilities, Beta0, according to the two-state equation Beta0 = 3Deltamu12(mu12)2/(Emax)2 (mu12 = transition dipole moment, Emax = MLCT/ILCT energy). In contrast with related RuII ammine complexes, replacement of a central E-ethylene bond with a 1,4-phenylene unit does not appear to be an especially effective strategy for combating the NLO transparency-efficiency tradeoff in these pdma complexes. Single-crystal X-ray studies with the complex salts 2 and 3 and also with the pro-ligand salt [Phbpvb+] PF6.0.5HPF6 show that these materials all adopt centrosymmetric packing structures. 相似文献
6.
Yun Xing YAN* Xiao Qiang YU Dong WANG Xian ZHAO Qi FANG Min Hua JIANG State Key Laboratory of Crystal Materials Shandong University Ji抧an 《中国化学快报》2003,14(11):1203-1206
Two-photon absorption (TPA) is a process in which two photons are simultaneously absorbed to an excited state via a virtual state. The synthesis of organic optical materials with large TPA cross section has become a subject of great interest in recent years due to various application such as three-dimensional fluorescence imaging1, optical data storage2,3 and lithographic microfabrication4-6. Recently we have synthesized a new organic dye DEAHAS that is a symmetrically substituted stilbe… 相似文献
7.
Dessingou J Tabbasum K Mitra A Hinge VK Rao CP 《The Journal of organic chemistry》2012,77(3):1406-1413
The structurally characterized lower rim 1,3-di{4-antipyrine}amide conjugate of calix[4]arene (L) exhibits high selectivity toward Hg(2+) among other biologically important metal ions, viz., Na(+), K(+), Ca(2+), Mg(2+), Mn(2+), Fe(2+), Co(2+), Ni(2+), Cu(2+), Zn(2+), Cd(2+), Hg(2+), Pb(2+), and Ag(+) as studied by fluorescence, absorption, and ESI MS. L acts as a sensor for Hg(2+) by switch-off fluorescence and exhibits a lowest detectable concentration of 1.87 ± 0.1 ppm. The complex formed between L and Hg(2+) is found to be 1:1 on the basis of absorption and fluorescence titrations and was confirmed by ESI MS. The coordination features of the mercury complex of L were derived on the basis of DFT computations and found that the Hg(2+) is bound through an N(2)O(2) extending from both the arms to result in a distorted octahedral geometry with two vacant sites. The nanostructural features such as shape and size obtained using AFM and TEM distinguishes L from its Hg(2+) complex and were different from those of the simple mercuric perchlorate. L is also suited to sense pyrimidine bases by fluorescence quenching with a minimum detection limit of 1.15 ± 0.1 ppm in the case of cytosine. The nature of interaction of pyrimidine bases with L has been further studied by DFT computational calculations and found to have interactions through a hydrogen bonding and NH-π interaction between the host and the guest. 相似文献
8.
A new fluorescent peptidyl chemosensor based on the mercury binding MerP protein with fluorescence resonance energy transfer (FRET) capabilities has been synthesized via Fmoc solid-phase peptide synthesis. The metal chelating unit, which is flanked by the fluorophores tryptophan (donor) and dansyl (acceptor), contains amino acids from MerP's metal binding loop (sequence: dansyl-Gly-Gly-Thr-Leu-Ala-Val-Pro-Gly-Met-Thr-Cys-Ala-Ala-Cys-Pro-Ile-Thr-Val-Lys-Lys-Gly-Gly-Trp-CONH(2)). A FRET enhancement or 'turn-on' response was observed for Hg(2+) as well as for Zn(2+), Cd(2+) and Ag(+) in a pure aqueous solution at pH 7.0. The emission intensity of the acceptor was used to monitor the concentration of these metals ions with detection limits of 280, 6, 103 and 496 microg L(-1), respectively. No response was observed for the other transition, alkali and alkaline earth metals tested. The fluorescent enhancement observed is unique for Hg(2+) since this metal generally quenches fluorescence. The acceptor fluorescence increase resulting from metal binding-induced FRET suggests a sensor that is inherently more sensitive than one based on quenching by the binding event. 相似文献
9.
A series of amphiphilic intramolecular charge-transfer fluorescent molecular sensors AS1-3, equipped with a rod-shaped hydrophobic 2-phenylbenzoxazole fluorophore and a hydrophilic tetraamide Hg(2+)-ion receptor, have been prepared. These sensor molecules could be incorporated into the hydrophobic sodium dodecyl sulfate (SDS) micelle, which is confirmed by the clear spectral blue shift and emission enhancement observed at the critical micelle concentration of SDS. Systematic examination of the sensor-Hg(2+) complexation, by using both UV/visible and fluorescence spectroscopy, indicates that SDS significantly modulates both the binding event and signal transformation of these sensor molecules. The potential advantages are fourfold: 1) SDS substantially increases the Hg(2+)-ion association constant and results in an amplified sensitivity. 2) SDS initiates spectral features which facilitate Hg(2+)-ion analysis, for example, in addition to the strengthened fluorescence of the free sensors AS1-3, the original "on-off" response of AS2 toward the Hg(2+) ion is transformed into a self-calibrated two-wavelength ratiometric signal, while for AS3, Hg(2+)-ion complexation in the presence of SDS results in a 180 nm blue shift, which is preferred to the 51 nm spectral shift obtained without SDS. 3) Thermoreversible tuning of the dynamic detection range is realized. 4) Highly specific Hg(2+)-ion identification could be achieved by using the SDS-induced fingerprint emission (358 nm) of the AS2-Hg(2+) complex. Altogether, this work demonstrates a convenient and powerful strategy that remarkably elevates the performance of a given fluorescent molecular sensor. It also implies that for a specific utilization, much attention should be paid to the microenvironment in which the sensor resides, as the behavior of the sensor might be different from that in the bulk solution. 相似文献
10.
A dye intermediate, 1-amino-8-naphthol-3,6-disulfonic acid sodium (ANDS) was first used to selectively recognize Hg(II) in aqueous solutions with its fluorescence being strong quenched. The fluorescence quenching of ANDS was attributed to the formation of an inclusion complex between Hg(II) and ANDS by 2:1 complex ratio (K=6.2 x 10(9)), which has been utilized as the basis of the fabrication of the Hg(II)-sensitive fluorescent chemosensor. The analytical performance characteristics of the proposed chemosensor were investigated. The sensor shows a linear response toward Hg(II) in the concentration range 2.9 x 10(-6) to 5.5 x 10(-5)M with a limit of detection of 5.3 x 10(-7)M, and a working pH range from 5.0 to 9.0. It shows excellent selectivity for Hg(II) over a large number of cations such as alkali, alkaline earth and transitional metal ions. The proposed method was utilized successfully for the detection of Hg(2+) in water samples. 相似文献
11.
Ma LJ Chen L Chen G Li HW Yang L Wu Y Wang D Xie J 《Photochemistry and photobiology》2012,88(4):824-830
In this study, we report a histidine-based fluorescence probe for Cu(2+) and Hg(2+), in which the amino group and imino group were modified by two common protective groups, 9-fluorenylmethoxycarbonyl and trityl group, respectively. In a water/methanol mixed solution, the probe displayed a selective fluorescence "turn-off" response to Cu(2+) when the ratio of CH(3)OH/H(2)O was higher than 1:1. Specifically, when the solvent is changed to 1:1 methanol/water, the 304 nm fluorescence peak is enhanced, while the 317 nm peak is weakened, upon addition of either Cu(2+) or Hg(2+) ions. The mechanism for such distinct responses of the probe to Cu(2+) and Hg(2+) was further clarified by using NMR and molecular simulation. The experiment results indicated that the polarity of solvent could influence the coordination mode of 1 with Cu(2+) and Hg(2+), and control the fluorescence response as a "turn-off" or ratiometric probe. 相似文献
12.
The electronic spectroscopy and photochemistry of the trans isomers of 3-(N-phenylamino)stilbene (m1c), 3-(N-methyl-N-phenylamino)stilbene (m1d), 3-(N,N-diphenylamino)stilbene (m1e), and 3-(N-(2,6-dimethylphenyl)amino)stilbene (m1f) and their double-bond constrained analogues m2a-m2c and m2e are reported. When compared with trans-3-aminostilbene (m1a), m1c-m1e display a red shift of the S0 --> S1 absorption and fluorescence spectra, lower oscillator strength and fluorescence rate constants, and more efficient S1 --> T1 intersystem crossing. Consequently, the N-phenyl derivatives m1c-m1e have lower fluorescence quantum yields and higher photoisomerization quantum yields. The corresponding N-phenyl substituent effect in m2a-m2e is similar in cyclohexane but smaller in acetonitrile. This is attributed to the weaker intramolecular charge transfer character for the S1 state of m2 so that the rates for intersystem crossing are less sensitive to solvent polarity. It is also concluded that N-phenyl substitutions do not change the triplet mechanism of photoisomerization for m1 in both nonpolar and polar solvents. Therefore, the "m-amino conjugation effect" reinforces the "m-amino effect" on fluorescence by further reducing its rate constants and highlights the N-phenyl-enhanced intersystem crossing from the "amino-conjugation effect" by making S1 --> T1 the predominant nonradiative decay pathway. 相似文献
13.
Barlow S Risko C Chung SJ Tucker NM Coropceanu V Jones SC Levi Z Brédas JL Marder SR 《Journal of the American Chemical Society》2005,127(48):16900-16911
(E)-4,4'-Bis[bis(4-methoxyphenyl)amino]stilbene, 1, (E,E)-1,4-bis[4-[bis(4-methoxyphenyl)amino]styryl]benzene, 2, and two longer homologues, (E,E,E)-4,4'-bis[4-[bis(4-methoxyphenyl)amino]styryl]stilbene, 3, and (E,E,E,E)-1,4-bis(4-[4-[bis(4-methoxyphenyl)amino]styryl]styryl)benzene, 4, have been oxidized to their mono- and dications using tris(4-bromophenyl)aminium hexachloroantimonate. The intervalence charge-transfer (IVCT) band of 1(+) is narrow and asymmetric and exhibits only weak solvatochromism. Analysis of this band indicates that 1(+) is a class-III or class-II/III borderline mixed-valence species. In contrast, a broad, strongly solvatochromic IVCT band is observed for 2(+), indicating that this species is a class-II mixed-valence species. The assignment of 1(+ ) and 2(+) as symmetric class-III and unsymmetric class-II species, respectively, is also supported by AM1 calculations. Hush analysis of the IVCT bands of both 1(+) and 2(+) gives larger electronic couplings, V, than for their analogues in which the double bonds are replaced with triple bonds. The diabatic electron-transfer distance, R, in 1(+) can be estimated by comparison of the V estimated by Hush analysis and from the IVCT maximum; it is considerably less than the geometric N-N separation, a result supported by quantum-chemical estimates of R for 1(+)-4(+). In 3(+) and 4(+), the IVCT is largely obscured by an intense absorption similar to a band seen in the corresponding dications and to that observed in the monocation of a model compound, (E,E,E)-1-[bis(4-methoxyphenyl)amino]-4-[4-[4-(4-tert-butylstyryl)styryl]styryl]benzene, 5, containing only one nitrogen redox center; we attribute this band to a bridge-to-N(+) transition. The corresponding dications 1(2+)-4(2+) show a complementary trend in the coupling between redox centers: the shortest species is diamagnetic, while the dication with the longest bridge behaves as two essentially noninteracting radical centers. 相似文献
14.
A copper(II) ion-selective on-off-type fluoroionophore based on zinc porphyrin-dipyridylamino 总被引:1,自引:0,他引:1
A new copper(II) fluorescent sensor 5,10,15,20-tetra((p-N,N-bis(2-pyridyl)amino)phenyl)porphyrin zinc (1) has been designed and synthesized by the Ullmann-type condensation of bromoporphyrin zinc with 2,2'-dipyridylamine (dpa) under copper powder as a catalyst as well as with K2CO3 as the base in a DMF solution. It consists of two separately functional moieties: the zinc porphyrin performs as a fluorophore, and the dpa-linked-to-zinc porphyrin acts as a selected binding site for metal ions. It displays a high selectivity and antidisturbance for the Cu2+ ion among the metal ions examined (Na+, Mg2+, Cr3+, Mn2+, Fe2+, Co2+, Ni2+, Cu2+, Ag+, Zn2+, Cd2+, Hg2+, and Fe3+) and exhibits fluorescence quenching upon the binding of the Cu2+ ion with an "on-off"-type fluoroionophoric switching property. The detection limit is found to be 3.3 x 10(-7) M (3s blank) for Cu2+ ion in methanol solution, and its fluorescence can be revived by the addition of EDTA disodium solution. The design strategy and remarkable photophysical properties of sensor 1 help to extend the development of fluorescent sensors for metal ions. 相似文献
15.
The synthesis, structure, and photochemical behavior of the trans isomers of 4-(N-phenylamino)stilbene (1c), 4-(N-methyl-N-phenylamino)stilbene (1d), 4-(N,N-diphenylamino)stilbene (1e), and 4-(N-(2,6-dimethylphenyl)amino)stilbene (1f) are reported and compared to that of 4-aminostilbene (1a) and 4-N,N-dimethylaminostilbene (1b). Results for the corresponding 3-styrylpyridine (2) and 2-styrylnaphthalene analogues (3) are also included. The introduction of N-phenyl substituents to 4-aminostilbenes leads to a more planar ground-state geometry about the nitrogen atom, a red shift of the absorption and fluorescence spectra, and a less distorted structure with a larger charge-transfer character for the fluorescent excited state. Consequently, the N-phenyl derivatives 1c-e have low photoisomerization quantum yields and high fluorescence quantum yields at room temperature, in contrast to the behavior of 1a, 1b, and most unconstrained monosubstituted trans-stilbenes. The isomerization of 1c and 1d is a singlet-state process, whereas it is a triplet-state process for 1e, presumably due to a relatively higher singlet-state torsional barrier. The excited-state behavior of 1f resembles 1a and 1b instead of 1c-e as a consequence of the less planar amine geometry and weaker orbital interactions between the N-phenyl and the aminostilbene groups. Such an N-phenyl substituent effect is also found for 2 and 3 and thus appears to be general for stilbenoid systems. The nature of this effect can be described as an "amino conjugation effect". 相似文献
16.
Three new compounds bearing furyl, aryl, or thienyl moieties linked to an imidazo-crown ether system (1, 2, and 3) were synthesized and fully characterized by elemental analysis, infrared, UV-vis absorption, and emission spectroscopy, X-ray crystal diffraction, and MALDI-TOF-MS spectrometry. The interaction toward metal ions (Ca(2+), Cu(2+), Ni(2+), and Hg(2+)) and F(-) has been explored in solution by absorption and fluorescence spectroscopy. Mononuclear and binuclear metal complexes using Cu(2+) or Hg(2+) as metal centers have been synthesized and characterized. Compounds 2 and 3 show a noticeable enhancement of the fluorescence intensity in the presence of Ca(2+) and Cu(2+) ions. Moreover compound 3 presents a dual sensory detection way by modification of the fluorimetric and colorimetric properties in the presence of Cu(2+) or Hg(2+). EPR studies in frozen solution and in microcrystalline state of the dinuclear Cu(II)3 complex revealed the presence of an unique Cu(2+) type. 相似文献
17.
Dansyl-anthracene dyads 1 and 2 in CH(3)CN-H(2)O (7:3) selectively recognize Cu(2+) ions amongst alkali, alkaline earth and other heavy metal ions using both absorbance and fluorescence spectroscopy. In absorbance, the addition of Cu(2+) to the solution of dyads 1 or 2 results in appearance of broad absorption band from 200 nm to 725 nm for dyad 1 and from 200 nm to 520 nm for dyad 2. This is associated with color change from colorless to blue (for 1) and fluorescent green (for 2). This bathochromic shift of the spectrum could be assigned to internal charge transfer from sulfonamide nitrogen to anthracene moiety. In fluorescence, under similar conditions dyads 1 and 2 on addition of Cu(2+) selectively quench fluorescence due to dansyl moiety between 520-570 nm (for 1)/555-650 nm (for 2) with simultaneous fluorescence enhancement at 470 nm and 505 nm for dyads 1 and 2, respectively. Hence these dyads provide opportunity for ratiometric analysis of 1-50 μM Cu(2+). The other metal ions viz. Fe(3+), Co(2+), Ni(2+), Cd(2+), Zn(2+), Hg(2+), Ag(+), Pb(2+), Li(+), Na(+), K(+), Mg(2+), Ca(2+), Ba(2+) do not interfere in the estimation of Cu(2+) except Cr(3+) in case of dyad 1. The coordination of dimethylamino group of dansyl unit with Cu(2+) causes quenching of fluorescence due to dansyl moiety between 520-600 nm and also restricts the photoinduced electron transfer from dimethylamino to anthracene moiety to release fluorescence between 450-510 nm. This simultaneous quenching and release of fluorescence respectively due to dansyl and anthracene moieties emulates into Cu(2+) induced ratiometric change. 相似文献
18.
Azine-based receptor for recognition of Hg2+ ion: crystallographic evidence and imaging application in live cells 总被引:1,自引:0,他引:1
Suresh M Mandal AK Saha S Suresh E Mandoli A Di Liddo R Parnigotto PP Das A 《Organic letters》2010,12(23):5406-5409
A newly synthesized azine-based receptor (L) is found to show remarkable specificity toward the Hg(2+) ion in aqueous media over other metal ions. Coordination of L to Hg(2+) induces a detectable change in color and a turn-on fluorescence response. Restricted C=N isomerization of the azine moieties in the excited state as well as the Photoinduced Electron Transfer (PET) involving the lone pair of electrons of N(1)/N(2) on coordination of L to the Hg(2+) ion account for the turn-on fluorescence response. This reagent could be used for imaging the accumulation of Hg(2+) ions in Epithelial cell line KB 31 cells. 相似文献
19.
Kumar DK Jose DA Dastidar P Das A 《Langmuir : the ACS journal of surfaces and colloids》2004,20(24):10413-10418
A series of pyridyl amides derived from isonicotinic acid, nicotinic acid, and benzoic acid have been synthesized. Only N-(4-pyridyl)isonicotinamide 1 is found to be an efficient hydrogelator with a minimum gelator concentration of 0.37 wt %. A wide range of concentrations (0.37-20 wt %) could be used to form hydrogels. The other amides, namely, N-(3-pyridyl)isonicotinamide 2, N-(2-pyridyl)isonicotinamide 3, N-(phenyl)isonicotinamide 4, N-(4-pyridyl)nicotinamide 5, N-(3-pyridyl)nicotinamide 6, and N-(4-pyridyl)benzamide 7, did not show any gelation properties. Fourier transform infrared spectroscopy, variable temperature 1H NMR, single-crystal diffraction and X-ray powder diffraction (XRPD), and scanning electron microscopy have been used to characterize the gel. Single-crystal diffraction and XRPD studies indicate that the morph responsible for gel formation is different from that in its bulk solid and xerogel. 相似文献
20.
The synthesis, electrochemical, optical, and metal-cation-sensing properties of ferrocene-glycine conjugates C(30)H(38)O(8)N(8)Fe (2) and C(20)H(24)O(4)N(4)Fe (3) have been documented. Both compounds 2 and 3 behave as very selective redox (ΔE(1/2) = 217 mV for 2 and ΔE(1/2) = 160 mV for 3), chromogenic, and fluorescent chemosensors for Hg(2+) cations in an aqueous environment. The considerable changes in their absorption spectra are accompanied by the appearance of a new low-energy peak at 630 nm (2, ε = 1600 M(-1) cm(-1); 3, ε = 822 M(-1) cm(-1)). This is also accompanied by a strong color change from yellow to purple, which allows a prospective for the "naked eye" detection of Hg(2+) cations. These chemosensors present immense brightness and fluorescence enhancement (chelation-enhanced fluorescence = 91 for 2 and 42 for 3) following Hg(2+) coordination within the limit of detection for Hg(2+) at 7.5 parts per billion. 相似文献