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1.
N-(3-Azido-2-nitroxypropyl)-N-alkylnitramines andN-(2,3-diazidopropyl)-N-alkylnitramines were prepared by nitration and azidation ofN-alkyl-N-(2-hydroxy-3-chloropropyl)sulfamates andN-(3-azido-2-hydroxypropyl)-N-alkylsulfamates.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 206–208, January, 1999. 相似文献
2.
Salts ofN-(β-hydroxyalkyl)-N′-hydroxydiazeneN-oxides, RCH(OH)CH2N(O)=NO− M+ (R=Me, Pri, or But; and M=Li, Na, K, Ag, NH4, or Me4N), were prepared. Their alkylation with alkyl halides R′X (X=Cl, Br, or I) and dimethyl sulfate was studied. Generally, alkylation
afforded mixtures ofN-(β-hydroxyalkyl)-N′-alkoxydiazeneN-oxides RCH(OH)CH2N(O)=NOR′ andO-alkyl-N-(β-hydroxyalkyl)-N-nitrosohydroxylamines RCH(OH)CH2N(NO)OR′.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1996–2001, October, 1998. 相似文献
3.
D. V. Shishkin E. R. Mukhamed’yarova N. Z. Baibulatova V. A. Dokichev Yu. V. Tomilov 《Chemistry of Natural Compounds》2007,43(3):293-297
Diastereomers of N-(2-(1-adamantyl)-2-hydroxyethyl)cytisine were synthesized by reduction of N-(2-(1-adamantyl)-2-oxoethyl)cytisine with NaBH4. Their structures were established using x-ray structure analysis.
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Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 244–247, May–June, 2007. 相似文献
4.
D. V. Shishkin A. R. Shaimuratova A. N. Lobov N. Z. Baibulatova L. V. Spirikhin M. S. Yunusov N. S. Makara N. Zh. Baschenko V. A. Dokichev 《Chemistry of Natural Compounds》2007,43(2):190-196
Derivatives of N-(2-hydroxyethyl)cytisine, N-(2-hydroxypropyl)-, N-(2-hydroxy-2-(1-adamantyl)ethyl)-, and N-(2-hydroxy-2-phenylethyl)cytisine, were synthesized by reduction of N-(2-oxopropyl)-, N-(2-oxo-2-(1-adamantyl)ethyl)-and N-(2-oxo-2-phenylethyl)cytisine with metal hydrides. The antiarrhythmic and analgesic activities of the prepared compounds
were investigated.
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Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 157–162, March–April, 2007. 相似文献
5.
B. F. Kukharev 《Russian Chemical Bulletin》1997,46(8):1482-1483
Heating cyclohexanespiro-2-oxazolidine at 160–200°C in the presence of protic acids results in its decomposition to giveN-(2-hydroxyethyl)cyclohexylamine,N-(2-hydroxyethyl)-4,5,6,7-tetrahydroindole, and 2-cyclohexylidenecyclohexanone. The possible pathways leading to these compounds
are discussed.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1547–1548, August, 1997. 相似文献
6.
I. M. Aladzheva O. V. Bykhovskaya P. V. Petrovskii T. A. Mastryukova 《Russian Chemical Bulletin》2007,56(12):2456-2459
Two methods for the synthesis of N-(2-chloroethyl)glycine and-DL-alanine esters are proposed: 1) reductive amination of the C=O group of glyoxilic or pyruvic acids upon treatment with 2-chloroethylamine
and sodium cyanoborohydride in methanol and 2) alkylation of 2-chloroethylamine with α-haloalkanoic acid esters in K2CO3-MeCN two-phase system.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2372–2374, December, 2007. 相似文献
7.
B. S. Fedorov N. I. Golovina V. V. Arakcheeva M. A. Fadeev G. V. Strukov V. V. Kedrov G. V. Shilov L. O. Atovmyan 《Russian Chemical Bulletin》1999,48(8):1584-1586
The reaction ofN,N′-bis(2-nitroxyethyl)pyridine-2,6-dicarboxamide with PdCl2 afforded previously unknowncis-(N-2-nitroxyethylpicolinamide-N,N′)dichloropalladium(II) andcis-[2-(2-pyridyl)-2-oxazoline-N,N′]dichloropalladium(II), which were isolated as a cocrystallizate of the molecular compounds. Its structure was established
by X-ray diffraction analysis.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1604–1606, August, 1999. 相似文献
8.
Methylene-bis[N′-oxydiazene-N-(β-hydroxyalkyl)N-oxides] were synthesized by the reaction of salts ofN-(β-hydroxyalkyl)-N′-hydroxydiazeneN-oxides with diahalomethanes. The effect of the nature of the starting reagents and the reaction condtions on the yields of
the target compounds was studied.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2266–2269, November, 1998. 相似文献
9.
1H NMR spectra in CDCl3 of poly(N-vinylpyrrolidone), epoxidized poly(N-vinyl-pyrrolidone), and products derived from the latter by modification with amino acids (glycine, β-alanine, γ-aminobutyric
acid, and ε-aminocaproic acid) were examined. The 1H NMR spectra of the modified polymers contain signals for water protons due to different centers of water sorption. These
signals differ in chemical shift and integral intensity and indicate a changed spatial packing of the polymer as the result
of its modification.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2377–2380, October, 2005. 相似文献
10.
Thiocarbamoylation of 5-aminosalicylic acid with tetramethylthiuram disulfide afforded 5-(N′,N′-dimethylthioureido)salicyclic acid. Treatment of the latter with mineral acids or Ac2O gave 5-isothiocyanatosalicylic acid whose reaction with ethanolamine yielded 5-[N′-(2-hydroxyethyl)thioureido]salicylic acid. The latter underwent cyclization under the action of TsOH to form 5-(2-thiazolin-2-ylamino)salicylic
acid.
For Part 2, see Ref. 1.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2315–2318, December, 1999. 相似文献
11.
V. S. Reznik V. D. Akamsin I. V. Galyametdinova A. V. Chernova R. R. Shagidullin 《Russian Chemical Bulletin》2000,49(3):490-494
A method for the synthesis of hypotensive alkyl(phenyl)[ω-(N-phenylpiperazino)alkyl]-phosphine oxides by reacting alkyl(ω-haloalkyl)phenylphosphine oxides withN-phenylpiperazine was elaborated. Phenyl[γ-(N-phenylpiperazino)propyl]propylphosphine oxide reacts with alkyl halides to give [γ-(N-alkyl-N′-phenylpiperazinio)propyl]phenyl(propyl)oxophosphine halides.
For Part 1 see Ref. 1.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 488–492, March, 2000. 相似文献
12.
O. A. Luk'yanov G. A. Smirnov S. V. Nikitin A. Z. Lisitsin 《Russian Chemical Bulletin》1999,48(1):124-130
Some characteristic features of reactions ofN-(β-hydroxyalkyl)-N′-hydroxydiazeneN-oxide salts with various α- and β-functionalized alkyl halides were established. Some α-and β-functionalizedN-(β-hydroxyalkyl)-N′-alkoxydiazeneN-oxides and e ethylenebis[N-(β-hydroxyalkyl)-N′-oxydiazeneN-oxides] were synthesized for the first time.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 123–129, January, 1999. 相似文献
13.
I. M. Aladzheva O. V. Bykhovskaya P. V. Petrovskii K. A. Lyssenko M. Yu. Antipin T. A. Mastryukova 《Russian Chemical Bulletin》2005,54(11):2635-2641
A facile method was developed for the synthesis of N-(3-phosphonopropyl)-substituted α-amino acids and their phosphine oxide analogs based on hydrolysis of 2-oxo-1,2-azaphospholanes
and 1,2-azaphospholanium salts prepared from readily available reagents. A chelate CuII
N-[(3-diphenylphosphoryl)propyl]glycinate was isolated.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2551–2556, November, 2005. 相似文献
14.
V. S. Renzik V. D. Akamsin I. V. Galyametdinova S. G. Fattakhov B. E. Ivanov 《Russian Chemical Bulletin》1999,48(5):979-983
Dialkyl β-(2-aroxyethylamino)ethylphosphonates,N-[β-(2-methoxyphenoxy)ethyl]-N′-[β-(diethoxyphosphoryl)ethyl]-α,ω-diaminoalkanes, and diethyl β-(N-arylpiperazino)ethyl-phosphonates were synthesized by the reactions of dialkyl vinylphosphonates with β-aroxyethylamines,N-[β-(2-methoxyphenoxy)ethyl]-α,ω-diaminoalkanes, andN-aryl-piperazines, respectively. The compounds synthesized exhibit hypotensive and α-adrenolytic activities.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 987–991, May 1999. 相似文献
15.
V. A. Tartakovsky A. S. Ermakov D. B. Vinogradov P. V. Bulatov 《Russian Chemical Bulletin》1998,47(4):652-655
Nitration ofN-3-chloroalkoxy-2-hydroxypropyl-N-alkylsulfamates gave the correspondingN-3-chloroalkoxy-2-nitroxypropyl-N-alkylnitramines. Azidation of the latter resulted inN-azido-3-azidoalkoxypropyl-N-alkylnitramines.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 673–676, April, 1998. 相似文献
16.
Subramanian Annalakshmi Kasi Pitchumani 《Journal of inclusion phenomena and macrocyclic chemistry》2007,57(1-4):403-408
The effect of cyclodextrin inclusion complex formation on the intramolecular charge transfer (ICT) of the included 4-N,N-dimethylamino-2-strylquinoline (2-StQ-NMe2) has been studied in detail. 2-StQ-NMe2 in presence of α-, β-, γ- and HP-α- and Hp-β-CDs predominantly exhibits ICT fluorescence predominantly than the emission
from locally excited state, whereas in presence of HP-γ-CD the later is observed. In presence of α-CD, 2:1 complexation of
the 2-StQ-NMe2 is observed in addition to 1:1 complexation. The observed results are explained by the CD cavity size and an active role
for the secondary hydroxyl groups present in the wider rim of the CD cavity and also which finds support from absorption,
emission, lifetime and molecular modeling studies.
Electronic supplementary material The online version of this article (doi: ) contains supplementary material, which is available to authorized users. 相似文献
17.
The geometric parameters, the charge distribution, and the energetics of N-methyl-2-(N-ethylanilino)-3-(indol-1-yl)-and N-methyl-2-(N-ethylanilino)-3-(indol-3-yl)maleimides and their conjugated acids were studied by density functional theory calculations
at the B3LYP/6-31G(d) level. The mechanism of the tandem hydride transfer/cyclization sequence, which occurs after protonation
of N-methyl-2-(N-ethylanilino)-3-(indol-1-yl)-and N-methyl-2-(N-ethylanilino)-3-(indol-3-yl)maleimides, was analyzed. The investigation of the potential energy surface for the tandem hydride
transfer/cyclization of the iminium cation that formed upon protonation revealed that the hydride transfer followed by intramolecular
cyclization at position 7 of the indole fragment in N-methyl-2-(N-ethylanilino)-3-(indol-1-yl)maleimide is the preferable process, unlike alternative intramolecular cyclization involving
the cationic center at the C(2) atom of the indole fragment and the benzene ring of the N-ethylaniline fragment of the indoleninium cation in N-methyl-2-(N-ethylanilino)-3-(indol-3-yl)maleimide. A study of the key intermediates of the assumed reaction mechanism demonstrated that
these intermediates are actually stationary points on the potential energy surface (minima and transition states).
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2069–2073, December, 2006. 相似文献
18.
V. Yu. Korotaev Yu. A. Skorik A. Yu. Barkov M. I. Kodess A. Ya. Zapevalov 《Russian Chemical Bulletin》2005,54(11):2545-2549
3,3,3-Trifluoro-N′-(3-trifluoromethylphenyl)-1,2-propanediamine (5) was synthesized by the reaction of 2-diazo-1,1,1-trifluoro-3-nitropropane or 3,3,3-trifluoro-1-nitropropene with 3-aminobenzotrifluoride
followed by the reduction of the nitro group. The Michael 1,4-addition of diamine 5 to acrylic acid occurs only at the N(1) atom and affords N-mono-or N,N-dicarboxyethyl derivatives 6 and 7, depending on the reactant ratio. Protolytic equilibria 5–7 in aqueous solutions were studied by pH-potentiometry and UV spectroscopy. Only the aliphatic amino group can be protonated
in an aqueous solution, while the aromatic amino group remains unprotonated even in 12 M HCl. The stability constants of transition metal (Cu2+, Ni2+, Zn2+) complexes with ligands 5–7 were determined by pH-potentiometric titration. The stability of the complexes and selectivity of the ligands toward Cu2+ ions increase with an increase in the number of N-carboxyethyl groups.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2465–2469, November, 2005. 相似文献
19.
L. A. Musina E. E. Shul’ts L. A. Krichevskii S. M. Adekenov M. M. Shakirov G. A. Tolstikova 《Russian Chemical Bulletin》2006,55(2):331-337
The oxidation of N-acetyl-and N-benzoylanabasine with the tert-butyl hydroperoxide (TBHP)— MoCl5 system or MCPBA proceeds selectively at the nitrogen atom of the pyridine ring. The oxidation of N-methylanabasine under similar conditions gives a mixture of stereo-isomeric N-oxides at the piperidine nitrogen atom, their ratio depending on the reagent used. The oxidation of anabasine by TBHP— MoCl5 or MCPBA is accompanied by dehydrogenation and results in anabaseine N-oxide. The reactions of anabasine and anabaseine pyridine N-oxides with acetic anhydride were investigated. The substituted 1H-3-pyridin-2-ones were prepared.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 322—328, February, 2006. 相似文献
20.
(N-methyl-N-alkoxymethylaminomethyl)-dialkoxysilanes and bis[N-methyl-N-(dialkoxymethyl)amino]methanes were first obtained by the interaction of (N-methylaminomethyl) dialkoxy-R-silanes with chloromethyl alkyl ethers in yields of 40–67% and 10–25 %, respectively.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 382–383, February, 1995. 相似文献