基于光纤参量环形镜的光毫米波副载波产生

提出并验证了一种基于光纤参量环形镜(OPLM)和光纤光栅(FBG)的60GHz光毫米波副载波产生方案。理论上分析了OPLM的原理特性,发现可以利用OPLM同时完成光子微波信号的高次谐波产生和抽运滤波,直接获得光毫米波副载波信号。在实验验证中,从5GHz的基频信号出发,通过调制非线性和OPLM中的四波混频和滤波过程,完成高次谐波产生和抽运分离,成功得到60GHz的光毫米波副载波信号,表现出良好的性能。     

生物组织单光程光谱技术的理论研究

高灵敏度光谱检测技术在临床诊疗和组织光学参数测量中具有极其重要的意义。文章提出了一种差分调制激光光谱技术,将经过生物组织后的散射光与参考光的光程差转换为光谱信号的频率特征,通过相敏检测技术将不同频率的信号进行分离,从而实现生物组织散射光的光程分离。文章分析了差分调制激光光谱的机理及信号的谱特征,并基于文献中的生物组织散射光的光程分布,从理论上讨论了差拍信号的谱特征,即光源调制速率一定时,光谱信号中的主频成分位置只与散射光和参考光的光程差有关;生物组织对光信号的衰减系数会影响光谱信号中频率成分的能量强度分布。分析结果表明,差分调制激光光谱能对生物组织的光谱信号进行光程分离,从而实现生物组织的单光程光谱检测。     

Path-length distribution and path-length-resolved Doppler measurements of multiply scattered photons by use of low-coherence interferometry

We report first results of measurements by low-coherence Doppler interferometry of the path-length distribution of photons undergoing multiple scattering in a highly turbid medium. We use a Mach-Zehnder interferometer with multimode graded-index fibers and a superluminescent diode as the light source. The path-length distribution is obtained by recording of the heterodyne fluctuations that arise from the Brownian motion of particles in an Intralipid suspension as a function of the optical path length. The experimental path-length distribution is in good agreement with predictions of Monte Carlo simulations. In the heterodyne spectrum, an increase of the mean Doppler frequency with path length is observed.     

Measurement of optical constants for dense media by low-coherence dynamic light scattering

We perform the optical constants measurements for different absorption dense media by low-coherence dynamic light scattering (DLS) technique. The estimated particle size is used to calculate the scattering coefficient of particles suspended in dense media. The path-length resolved intensity distributions of light backscattered from the absorbing dense media are investigated experimentally by virtue of path-length resolved performance in low-coherence DLS measurements. The absorption coefficient can be obtained by applying the measured path-length resolved intensity distributions to the modified Lambert-Beer law. As a result, we proposed a new low-coherence DLS technique in simultaneous measurement of the scattering and absorption coefficients of absorbing dense media.     

The improvement of the measuring level of the surface curvature based on the spot-radius of a collimated Gaussian laser beam

In this study, we propose a system for determining the curvature of a material surface by a collimated Gaussian laser beam (CGLB) as the test light source. We will demonstrate that the measuring level can be improved and the experimental procedure can be reduced. The spot-radius of the test beam is nearly a constant and it is independent of the swing of the spot intensity. The proposed system can decrease the optical path-length and has the higher sensitivity and accuracy than the test system by using a Gaussian laser beam (GLB).     

全新的电导率特征矩阵方法及其在石墨烯THz频率光学特性上的应用

基于麦克斯韦方程组所要求的电磁场边界条件首次从理论上严格推导得到超薄导电体及其复合多层介质结构光学特性的一般计算方法及其特征矩阵公式, 其优点在于只要借助于导电体的电导率而无需知道其介电常数和磁导率即可计算得到反射、透射和吸收等光学特性, 克服了传统的传输矩阵方法必需知道组成材料的介电常数和磁导率才能获得其光学性质的问题, 并利用此方法获得了石墨烯及其复合多层结构在THz频率范围内反射、透射和吸收等光学行为.     

Bifocal optical coherenc refractometry of turbid media

We propose and demonstrate a novel technique, which we term bifocal optical coherence refractometry, for the rapid determination of the refractive index of a turbid medium. The technique is based on the simultaneous creation of two closely spaced confocal gates in a sample. The optical path-length difference between the gates is measured by means of low-coherence interferometry and used to determine the refractive index. We present experimental results for the refractive indices of milk solutions and of human skin in vivo. As the axial scan rate determines the acquisition time, which is potentially of the order of tens of milliseconds, the technique has potential for in vivo refractive-index measurements of turbid biological media under dynamic conditions.     

Fourier phase microscopy for investigation of biological structures and dynamics

By use of the Fourier decomposition of a low-coherence optical image field into two spatial components that can be controllably shifted in phase with respect to each other, a new high-transverse-resolution quantitative-phase microscope has been developed. The technique transforms a typical optical microscope into a quantitative-phase microscope, with high accuracy and a path-length sensitivity of lambda/5500, which is stable over several hours. The results obtained on epithelial and red blood cells demonstrate the potential of this instrument for quantitative investigation of the structure and dynamics associated with biological systems without sample preparation.     

基于多模光纤散斑的压缩感知在光学图像加密中的应用

为了安全高效地对图像信息进行传输,提出了一种新颖的基于多模光纤散斑的压缩感知结合双随机相位编码的光学图像加密方法.多模光纤产生的光斑作为压缩感知的测量矩阵,完成对图像的第一次压缩和加密,并且充当第一级密钥;再利用双随机相位编码技术进行第二次加密,实现对图像的完整加密过程,随机相位掩模板充当第二级密钥,解密过程与此相反.通过将光斑测量矩阵与用于压缩感知的常用随机测量矩阵进行对比研究后发现,使用光斑测量矩阵解密后的图像质量更好,而且相比于其他随机测量矩阵在硬件实现上的复杂性与高成本,光斑矩阵可以很容易地通过简单的光学器件来获得,且可以利用工作波长的改变来进行变换,也即第一级密钥非常容易变换.同时经研究表明,本文方法可以有效抵抗统计分析、噪声干扰和剪切等攻击,且对密钥敏感性高,具有良好的鲁棒性和安全性.因此,本文提出的这种基于光斑矩阵的压缩感知与双随机相位编码结合起来的加密方法,可以获得良好的加密效果与极大的密钥空间,并且易于在光学领域整合.     

A new Monte Carlo code for absorption simulation of laser-skin tissue interaction

In laser clinical applications, the process of photon absorption and thermal energy diffusion in the target tissue and its surrounding tissue during laser irradiation are crucial. Such information allows the selection of proper operating parameters such as laser power, and exposure time for optimal therapeutic. The Monte Carlo method is a useful tool for studying laser-tissue interaction and simulation of energy absorption in tissue during laser irradiation. We use the principles of this technique and write a new code with MATLAB 6.5, and then validate it against Monte Carlo multi layer (MCML) code. The new code is proved to be with good accuracy. It can be used to calculate the total power bsorbed in the region of interest. This can be combined for heat modelling with other computerized programs.     

近红外光谱无创生化检测中不定光程对模型精度的影响研究

利用近红外血流容积光谱相减方法无创伤定量分析人体血液生化成分时,获得的在体血液光谱对应的样品光程是不确定的。为研究样品间的光程差异对定标模型预测精度的影响,配制了30份模拟血清样品,利用可变光程样品池,采用傅里叶光谱仪分别测量了相同光程和不定光程两组样品的近红外光谱。以分析血清白蛋白成分为例,对两组样品的定标模型精度进行比较,结果显示不定光程组的模型精度与相同光程组的模型精度相比明显下降,交叉检验标准差(RMSECV)由110.0mg/dL增大至156.0mg/dL。采用多元散射校正算法对上述光谱数据校正后,RMSECV降低至98.1mg/dL。对比分析处理前后两组模型的精度,证实了采用适当的预处理方法能够有效校正不定光程引起的光谱误差,提高模型预测精度。     

Quantum-optical predictions for an experiment on the de Broglie waves detection

An experimental apparatus to detect de Broglie waves is discussed. The wave packets of two photons generated in the parametric-down conversion are overlapped in a modified Mach-Zehnder interferometer. The coincidence photodetection rate of photon pairs is evaluated, as a function of path-length of two interferometer arms, both by using the de Broglie concept of a real quantum wave and by the quantum optical approach. The different results of these two theories are compared, and it is shown that the proposed experiment can disprove either the theories.     

Spectral-domain optical coherence phase microscopy for quantitative phase-contrast imaging

We describe a novel microscopy technique for quantitative phase-contrast imaging of a transparent specimen. The technique is based on depth-resolved phase information provided by common path spectral-domain optical coherence tomography and can measure minute phase variations caused by changes in refractive index and thickness inside the specimen. We demonstrate subnanometer level path-length sensitivity and present images obtained on reflection from a known phase object and human epithelial cheek cells.     

Very long optical path-length from a compact multi-pass cell

The multiple-pass optical cell is an important tool for laser absorption spectroscopy and its many applications. For most practical applications, such as trace-gas detection, a compact and robust design is essential. Here, we report an investigation into a multi-pass cell design based on a pair of cylindrical mirrors, with a particular focus on achieving very long optical paths. We demonstrate a path-length of 50.31 m in a cell with 40 mm diameter mirrors spaced 88.9 mm apart—a 3-fold increase over the previously reported longest path-length obtained with this type of cell configuration. We characterize the mechanical stability of the cell and describe the practical conditions necessary to achieve very long path-lengths.     

具有三种颜色的白癜风皮肤的荧光光谱

将荧光光谱方法应用于具有三种颜色的白癜风皮肤特性的研究,在对荧光测量以及皮肤组织病理检查的基础上,建立了三色白癜风皮肤的光学模型,分析了皮肤黑色素的含量与分布,并进行了蒙特卡罗计算,其结果与实测结果基本一致。研究表明:具有三种颜色的白癜风皮肤可作为一个较好的皮肤黑色素含量与分布的模型;荧光光谱法可以探测到皮肤较深层(真皮层)的黑色素分布或其他组织光学特性;所建立的白癜风皮肤的光学模型及建模方法,所采用的光谱比率法等可以在皮肤光学的其他研究中应用。     

Speckle diagnostics of multiple scattering media with the use of frequency-modulated laser radiation

A method for probing randomly inhomogeneous multiple scattering media with the use of frequency-modulated laser radiation is considered. The method is based on analysis of the dependence of the blinking index of time-averaged speckles formed upon scattering of the probing radiation in a medium on the frequency modulation depth of the probing radiation. In the case of a binary frequency modulation, the blinking index of the detected speckle-modulated radiation is determined by the cosine Fourier transform of the probability density of the optical path-length difference of partial components of the scattered field in the probed medium. The values of the probability density of the optical path-length difference reconstructed with the use of the proposed method from the measured blinking index of speckles for model scattering media (fluoroplastic layer and layer of TiO₂ particles on a glass substrate) are in a good agreement with the results of statistical simulation of the probing radiation transfer in multiple scattering media.     

中红外无创血糖测量中光程变化对PLSR模型的影响研究

在测量人体皮肤中红外光谱的过程中,皮肤与ATR晶体之间的接触面积很难保持一致,导致倏逝波与人体皮肤的作用光程会产生差异。以光程变化信息与葡萄糖浓度信息之间的相关性为基础,建立了两个分析葡萄糖含量的偏最小二乘回归(PLSR)模型,RMSECV分别为31.3和4.52mg.dL-1;RMSEP分别为30.3和98.7mg.dL-1。结果表明,当光程变化信息与葡萄糖浓度信息之间偶然相关时,所建PLSR模型的预测精度与稳健性会受到不同程度的影响,随着二者之间相关性的增强,最优模型对葡萄糖信息的识别能力越来越弱。为提高中红外无创血糖测量分析结果的可靠性,避免获得伪优定标模型提供了实验依据。     

Mach-Zehnder interferometers assembled with optical microfibers or nanofibers

We demonstrate Mach-Zehnder interferometers (MZI) assembled using optical microfibers or nanofibers (MNFs) drawn from silica fibers and tellurite glasses. As-assembled MZIs, with dimensions of tens to hundreds of micrometers, show good interference fringes with extinction ratios of approximately 10 dB. The path-length difference of the MZI can be tuned by micromanipulation under an optical microscope. The MNF-assembled MZIs demonstrated here show advantages of easy fabrication, in situ tunability, and compact size.     

Optical soliton with group delay in microring coupled-resonator optical waveguides

This paper derives the dispersion relation of microring coupled-resonator optical waveguides (CROWs) without any approximation by using the transfer matrix method. Based on the established dispersion relation of CROWs it obtains the slow group velocity and dispersion coefficient. It finds that the effect of dispersion on optical pulses can be adjusted to balance the effect of nonlinearity by changing coupling coefficient or loss, so optical soliton with group delay can be obtained in microring CROWs. The optical soliton with group delay is of great significance for applications of microring CROWs in delay lines and optical buffers of future all-optical communication systems.     

Simulation of spectral reflectances in human skin tissue using ray tracing and GPU-based Monte Carlo method

We study a simulation of spectral reflectance in human skin tissue using ray-tracing software and the Monte Carlo method on the basis of a graphics processing unit (GPU). An analysis of light propagation using ray-tracing software has several advantages in that it can readily reproduce the complex structure of skin tissue, such as grooves of the skin surface or the boundaries of skin tissue layers, and perform optical simulation with optical elements close to those in a real experiment using only the ray-tracing software. Meanwhile, it has a serious disadvantage in that the simulation time is extremely long because the algorithm is CPU-based. To overcome this disadvantage, we propose a simulation method using the ray-tracing software and a GPU-based Monte Carlo simulation (MCS). The results of the simulation are shown and discussed.