A new glycoside from the leaves of Neoalsomitra integrifoliola

A new ionone glycoside （6R,9R）-blumenyl α-L-rhamnopyranosyl-（1 → 6）-β-D-gluco-pyranoside （1）, together with a new natural product 2-methoxyl-4-trans-pmpenyl-phenol α-L-rhamnopyranosyl-（1 → 6）-β-D-glucopyranoside （2）, was isolated from the leaves ofNeoalsomitra integrifoliola. Their structures were elucidated by chemical and spectral analysis. Compound 1 showed weak anti-inflammatory and low-level antioxidant activities.     

Two new steroidal glycosides from Ophiopogon japonicus

Two new C27-steroidal glycosides were isolated from the fibrous roots of Ophiopogon japonicus. The spectral analysis and chemical evidence revealed their chemical structures to be （25R）-spirost-5,14-dien-3β-yl-O-α-L-rhamnopyranosyl-（1 → 2）-β-D- xylopyranosyl-（1 → 4）-β-D-glucopyranoside （1） and ophiogenin 3-O-β-D-glucopyranoside （2）.     

Flavonoid triglycosides from the seeds of Camellia oleifera Abel

Two flavonoid triglycosides, kaempferol 3-O-{ β-D-glucopyranosyl-（1→2）-[α-L-rhamnopyranosyl-（1→ 6）]-β-D-glucopyranoside} （1） and kaempferol 3-O-{ β-D-xylopyranosyl-（1 → 2）-[α-L-rhamnopyranosyl-（1→6）]-β-D-glucopyranoside } （2）, were isolated from the seed of Camellia oleifera Abel. The absolute configuration of compound 1 was established on the basis of its X-ray analysis. Their cytotoxic activities and anti-HIV-RT activities were evaluated.     

A new C27-steroidal glycoside from Ophiopogon japonicus

A new C27-steroidal glycoside with three known compounds were isolated from the tuber of Ophiopogonjaponicus （Thunb.） Ker-Gawl. Based on the spectral analysis, including HRMS, 1H NMR, 13C NMR, DEPT, 1H-1H COSY, HMQC and HMBC, their chemical structures were determined as pennogenin-3-O-α-L-rhamnopyranosyl-（1→ 2）-β-D-xylopyranosyl-（1→ 4）-13-D-gluco- pyranoside （1）, pennogenin-3-O-α-L-rhamnopyranosyl-（1→ 2）-β-D-glucopyranoside （2）, ophiopojaponin C （3） and ophiopogonin D （4）. 2007 Jian Zhong Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.     

A New Flavonol Oligosaccaride from the Seeds of Aesculus chinensis

A new flavonol ologosaccharide,quercetin-3-O-[β-D-xylopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside-3′-O-β-D-glucopyranoside, named aesculfavoside was inolated from Aesculus chinensis.It′s structure was elucidatede by spectra FAB-MS,1D NMR and 2D NMR including ^1H NMR,^13C NMR,HMQC and HMBC techniques.     

A NEW TRITERPENE SAPONIN FROM THE STEMS AND LEAVES OF PANAX GINSENG

a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside on the basis of spectral analysis and chemical evidence.     

川麦冬皂苷类化学成分的研究

从川麦冬[Ophiopogon japonicus (Thunb.) Ker-Gawl.]中分离得到四个皂苷类成分, 分别鉴定为14-hydroxy sprengerinin C (1), sprengerinin C (2), ophiogenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (3)和β-胡萝卜苷(4, β-sitosterol β-D-glucopyranoside). 其中14-hydroxy sprengerinin C为新的C27甾体皂苷, 化合物sprengerinin C为首次从该植物分离得到. 运用现代波谱技术, 包括二维核磁共振谱和高分辨质谱, 对上述化合物的结构进行了确证.     

Septemloside III： A Nonasaccharide Saponin from the Bark of Kalopanax septemlobus （Thunb.） Koidz.

A nonasaccharide saponin, new hederagenin saponin, had been isolated from the bark ofKalopanax septemlobus (Thunb.) Koidz., and its structure was elucidated by HRESI-MS, NMR experi-ments and chemical analyses as 3-O-β-D-xylopyranosyl-(1→4)-13-D-xylopyranosyl-(1→3)-α-L-rhamno-pyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-β-D-xylopyranosyl-(1→3)-β-D-xylopyra-nosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside.     

Two New Steroidal Saponins from Tacca plantaginea

Two new C27 steroidal glycosides, named taccaoside A(1) and B(2), were isolated from the traditional Chinese herb Tacca plantaginea. The spectroscopic and chemical evidences revealed their structures to be 26-O-β-D-glucopyranosyl-(25R)-3β,26-dihydroxy furost-5,20-diene-3-O-[α-L-rhamnopyranosyl(1→2)]-[α-L-rhamnopyranosyl(1→3)]-β-D-glucopyranoside(1) and 26-O-β-D-glucopyranosyl-(25R)-3β,26-dihydroxy furost-5,20-diene-3-O-[α-L-rhamnopyranosyl-(1→2)]-[β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→3)]-β-D-glucopyranoside(2),respectively.     

A New Furost—20（22）—ene Oligoglycoside from Asparagus cochinchinensis

A new furost-20(22)-ene oligoglycoside named as aspacochioside C was isolated from the roots of Asparagus cochinchinensis (Lour.) Merr. Its structure was elucidated to be 26-O-β-D-glucopyranosyl-(25S)-5β- furost-20(22)-en-3β,26-diol-3-O-α-L-rhamnopyranosyl-( 1 →4)-β-D-glucopyranoside on the basis of spectroscopic techniques including 1D and 2D NMR experiments.     

Synthesis of an Ursolic Acid Saponin with N-Acetylglucosamine-containing Trisaccharide Residue

The focus of this work is the synthesis of an ursolic acid saponin with an N-acetylglucosamine-containingtrisaccharide residue.Therefore,ursolic acid 3-yl α-L-arabinopyranosyl-(1→2)-α-L-arabinopyranosyl-(1→6)-2-acetamido-2-deoxy-β-D-glucopyranoside(1)was concisely synthesized in convergent synthesis with 48.0% overallyield.The structure of saponin 1 was confirmed by ~1H NMR,~(13)C NMR and mass spectra.     

A new aryl glycoside from Euphorbia helioscopia L.

A new aryl glycoside,3″-O-galloyl-benzyl-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside,was isolated from Euphor- bia helioscopia L.,and its structure was elucidated on the basis of various spectroscopic data analysis.     

A new phenylethanoid glycoside from Rabdosia lophanthoides （Buch.-Ham.ex D.Don） Hara.

A new phenylethanoid glycoside,3-hydroxy-4-methoxy-β-phenylethoxy-O-α-L-rhamnopyranosyl-(1→3)-2-O-acetyl-O-β-D-glucopyranoside, named lophanthoside A,was isolated from Rabdosia lophanthoides(Buch.-Ham.ex D.Don) Hara.Its structure was determined by spectroscopic evidences.     

New triterpenoid sapoin from Ardisia gigantifolia Stapf

<正>One new triterpenoid sapoin with two known triterpenoid sapoins:3β-O-{α-L-rhamnopyranosyl-(1→3)-[β-D-xylopyranose-(1→2)]-β-D-glucopyranosyl-(1→4)-α-L-arabinopyranosyl}-3β-hydroxy-13β,28-epoxy-oleanan-16-oxo-30-al(1),3β-O-{α-L-rhamnopyranosyl-(1→3)-[(β-D-xylopyranosyl-(1→2)]-β-D-galactopyranosyl-(1→4)-[(β-D-glucopyranosyl-(1→2)]-α-L-ara-binopyranoside}-16α-hydroxy-13,28-epoxy-oleanane(2) and cyclamiretin A 3β-O-α-L-rhamnopyranosyl-(l→3)-[P-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranoside(3) were isolated fromArdisia gigantifolia Stapf.Their structures were elucidated by means of ~1H and ~(13)C NMR spectroscopic studies,including2D-NMR technique.     

A new dammarane-type triterpene saponin from Gynostemma pentaphyllum

<正>One new dammarane-type triterpene saponin,named(20S)-3β,20,21-trihydroxydammar-24-ene 3-O-[α-L-rhamnopyranosyl- (1→2)][β-D-xylopyranosyl(1→3)]-β-D-glucopyranoside(1),was isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino.Its structural elucidation was accomplished mainly on the basis of the interrelation of spectroscopic methods, such as IR,HR-TOF-MS,NMR.     

A New Steroidal Saponin from Dioscorea deltoidea Wall var. orbiculata

Bioactivity-guided fractionation led to the isolation of a new steroidal saponin, orbiculatoside B, together with a pair of furostanol saponins, protobioside and methyl protobioside, from the fresh rhizomes of Dioscorea deltoidea Wall var. orbiculate. The new compound was identified to be isonarthogenin 3-O-α-L-thamnopyranosyl(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside by various NMR techniques in combination with chemical methods. The three saponins showed strong activity against Pyricularia oryzae,and were cytotoxic to cancer cell line K562,HCT-15,A549, and A2780a in vitro.     

Antitumor triterpene saponins from Anemone flaccida

A new triterpenoid saponin, 3-O-[（6′-butyryl）-β-D-glucopyranosyl]-28-O-[α-L-rhamnopyranosyl-（1→4）-β-D-glucopyranosyl-（1→6）-β-D-glucopyranosyl] oleanolic acid, as well as three known triterpenoid saponins were isolated from the rhizomes of Anemone flaccida. Their structures were elucidated by spectroscopic methods. These compounds showed significant antitumor activities.     

Two new steroidal glucosides from Ophiopogon.japonicus （L.f.） Ker-Gawl

Two new steroidal glucosides, 26-O-β-D-glucopyranosyl （25S）-furost-5-ene-1β,3β,22α,26-tetraol l-O-β-D-xylopyranosyl- （1 → 3）-[α-h-rhamnopyranosyl-（1 → 2）]-[β-D-fueopyranoside and （25R） spirost-5-ene-3β,14α-diol-3-β-O-β-L-rhanmopyranosyl- （1 → 2）-[β-D-xylopyranosyl（1 → 4）]-[-β-D-glucopyranoside, were isolated from the Ophiopogon japonicus （L.f.） Ker-Gaw. Their structures were elucidated by spectroscopic methods.     

Two New Furostanol Glycosides from Asparagus cochinchinensis

Two new furostanol oligoglycosides named as aspacochioside A(1)and B(2) were isolated from the roots of Asparagus cochinchinensis (Lour.)Merr..Their structures were clucidated to be 3-O-[{α-L-rhamnopyranosyl-(1→4）}{β-D-glucopyranosyl}]-26-O-[β-D-glucopy-ranosyl]-(25S)-5β-furostane-3β，22α，26-triol 1 and 3-O-[{α-L-rhamnopyranosyl-(1→4）}{β-D-glu-copyeransoyl}]-26-O-[β-D-glucopyranosyl]-22α-methoxy-(25S)-5β-furostane-3β，26-diol 2 on the basis of spectroscopic techniques and chemical methods.     

Dracaenoside A and B, New C-22 Steroidal Lactone Glycosides from the Stem of Dracaena cochinchinensis

Two new C-22 steroidal lactone glycosides, named dracaenoside A and B were isolated from the methanol extract of the fresh stem of Dracaena cochinchinensis. Their structures were established as (20S)3β,14α,16β-trihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone 3-O-α-L-rhamnopyranosyl (1→2)[ α-L-rhamnopyranosyl (l→4)]-β-D-glucopyranoside and (20S)3β, 14α,16β-trihydroxy pregn-5-ene-22-carboxylic acid (22,16)-lactone 3-O-α-L-rhamnopyranosyl (1→2)[β-D-glucopyranosyl(1→3)]-β-D-glucopyranoside by means of 2D NMR spectral and chemical methods. It is the first time that steroidal lactone glycosides were isolated from the genus Dracaena.