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1.
I. V. Ukrainets N. L. Bereznyakova V. A. Parshikov A. V. Turov 《Chemistry of Heterocyclic Compounds》2007,43(10):1269-1274
By analogy with the 4-hydroxy derivatives, the bromination of N-allyl-4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid
leads to the closure of a five membered oxazole ring but, in contrast, it forms the 2-bromomethyl-4-carboxy-5-methyl-1,2-dihydrooxazolo[3,2-a]quinolinium
bromide salt.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1496–1502, October, 2007. 相似文献
2.
I. V. Ukrainets N. L. Bereznyakova O. V. Gorokhova A. V. Turov S. V. Shishkina 《Chemistry of Heterocyclic Compounds》2007,43(8):1001-1007
The hydrogenation of the benzene part of the molecule in N-allyl-substituted 4-hydroxy-2-quinolinones does not affect the
nature of their bromination by molecular bromine and gives 2-bromomethyl-5-oxo-1,2,6,7,8,9-hexahydro-5H-oxazolo[3,2-a]quinolines.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1180–1188, August, 2007. 相似文献
3.
I. V. Ukrainets N. L. Bereznyakova A. V. Turov S. V. Shishkina 《Chemistry of Heterocyclic Compounds》2007,43(7):871-878
The reaction of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carboxylic acid with thionyl chloride is accompanied
by a transformation of the oxazoloquinolone ring to give 4-chloro-1-(2,3-dichloropropyl)-2-oxo-1,2-dihydroquinoline-3-carboxylic
acid chloride.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1034–1042, July, 2007. 相似文献
4.
I. V. Ukrainets N. L. Bereznyakova A. V. Turov S. V. Slobodzian 《Chemistry of Heterocyclic Compounds》2007,43(9):1159-1166
Bromination of N-allyl-4-hydroxy-2-oxo-1,2-dihydroquinoline and N-allyl-5-ethoxycarbonyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine
is accompanied not only by closing of a five membered oxazole ring but also by a second bromination of the 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]-derivatives
formed at position 4.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1365–1373, September, 2007. 相似文献
5.
I. V. Ukrainets N. L. Bereznyakova O. V. Gorokhova A. V. Turov 《Chemistry of Heterocyclic Compounds》2007,43(11):1426-1433
The bromination of 3-allyl-4-hydroxy-2-oxo-1,2-dihydroquinoline by molecular bromine is accompanied by the closure of a five
membered furan ring and gives the corresponding 2-bromomethyl-3,9-dihydro-2H-furo[2,3-b]quinolin-4-one.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1677–1686, November, 2007. 相似文献
6.
I. V. Ukrainets I. A. Tugaibei N. L. Bereznyakova V. N. Kravchenko A. V. Turov 《Chemistry of Heterocyclic Compounds》2008,44(5):565-575
Alkyl-, arylalkyl-, and arylamides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid were prepared with a view
to establishing a structure-biological activity relationship. A comparative analysis has been made of their diuretic properties
and those of the structurally similar 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamides.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 718–729, May, 2008. 相似文献
7.
I. V. Ukrainets I. A. Tugaibei A. A. Tkach V. B. Rybakov A. V. Turov 《Chemistry of Heterocyclic Compounds》2008,44(3):316-323
Condensation of aminopyrazine with triethyl methanetricarboxylate gave ethyl 2-hydroxy-4-oxo-4H-pyrazino[1,2-a]pyrimidine-3-carboxylate.
According to X-ray analytical data the compound exists in the 2-hydroxy-4-oxo form in the crystal.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 411–419, March, 2008. 相似文献
8.
I. V. Ukrainets N. L. Bereznyakova G. P. Petyunin I. A. Tugaibei V. B. Rybakov V. V. Chernyshev A. V. Turov 《Chemistry of Heterocyclic Compounds》2007,43(6):729-739
An improved method for the preparation and purification of ethyl 2-hydroxy-4-oxo-4H-pyrido[1,2-a]-pyrimidine-3-carboxylates
is proposed. According to 1H and 13C NMR spectroscopic data the synthesized compounds exist in DMSO solution in the 2-hydroxy-4-oxo form while in the crystal
(at least for the case of the unsubstituted derivative) X-ray analysis shows that it occurs in the bipolar 2,4-dioxo form.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 864–876, June, 2007. 相似文献
9.
I. V. Ukrainets N. L. Bereznyakova I. A. Turaibei 《Chemistry of Heterocyclic Compounds》2008,44(1):50-63
Dialkylaminoalkylamides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids have been obtained as potential antiviral
agents. The special features of the spatial structure of one example of the synthesized compounds have been studied. Results
are given of the investigation of cytotoxicity and antiviral activity in relation to type 1 herpes virus and coronavirus.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 61–77, January, 2008. 相似文献
10.
11.
V. I. Terenin M. A. Butkevich A. P. Pleshkova 《Chemistry of Heterocyclic Compounds》2005,41(10):1327-1333
We have synthesized nitro derivatives of pyrrolo[1,2-a]pyrazines using a nitrating mixture and acetyl nitrate. We have obtained
the products of oxidation of the side chain of 1,6-substituted pyrrolo[1,2-a]-pyrazines.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1579–1586, October, 2005. 相似文献
12.
13.
E. Abele R. Abele P. Arsenyan S. Belyakov M. Veveris E. Lukevics 《Chemistry of Heterocyclic Compounds》2007,43(2):220-224
The reaction of 2-mercaptobenzimidazole with 1,3-dichloropropane or bis(chloromethyl)dimethylsilane in the two-phase catalytic
system of solid K2CO3-18-crown-6-toluene at 111°C leads to a selective formation of tricyclic benzimidazole sulfides in 56 and 92% yields. The
synthesized compounds were tested as hypocholesterolemic agents.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 274–279, February, 2007. 相似文献
14.
N. E. Golantsov A. V. Karchava V. M. Nosova M. A. Yurovskaya 《Russian Chemical Bulletin》2005,54(1):226-230
4-Substituted 1,2,3,4-tetrahydropyrazino[1,2-a]indoles were synthesized from 2-cyanoindole. (R)-4-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indole was obtained by the Mitsunobu reaction. Stereoselective reduction of 4-substituted 1,2,3,4-tetrahydropyrazino[1,2-a]indoles gave 4-substituted 1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles. (4R, 10aR)-4-Methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole was synthesized.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 221–225, January, 2005. 相似文献
15.
V. V. Lyaskovskyy Z. V. Voitenko V. A. Kovtunenko 《Chemistry of Heterocyclic Compounds》2007,43(3):253-276
Data on methods for the synthesis of isoindolo[2,1-a]benzimidazole and its derivatives and their chemical characteristics
are reviewed. Data from quantum-chemical calculations of certain structures are presented. Possible practical applications
of the compounds are indicated.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 323–351, March, 2007. 相似文献
16.
V. I. Terenin E. V. Kabanova N. A. Tselishcheva A. S. Ivanov N. V. Zyk 《Chemistry of Heterocyclic Compounds》2007,43(8):1038-1043
A study was carried out on the reaction of pyrrolo[1,2-a]pyrazines containing an alkyl, aryl, or aralkyl substituent at C-1
with trifluoroacetic anhydride. Trifluoroacetylation products may be formed either by reaction in the pyrrole ring or at the
aryl or aralkyl groups at C-1. Products of electrophilic substitution at C-6 are formed in the trifluoroacetylation of pyrrolo[1,2-a]pyrazines
containing at C-1 a substituent bulkier than a methyl group but lacking substituents at C-6 (the α-position of the pyrrole
ring).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1226–1233, August, 2007. 相似文献
17.
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19.
L. M. Potikha V. A. Kovtunenko A. V. Tarasevich 《Chemistry of Heterocyclic Compounds》2007,43(12):1551-1558
Oxidation of the hydrobromide of 6,11-dihydro-13H-isoquino[3,2-b]quinazolin-13-one with dimethyl sulfoxide leads to 11-hydroxy-11H-isoquino[3,2-b]quinazoline-6,13-dione,
and with hydrogen peroxide to the hydrobromide of 2-[(4-oxo-3,4-dihydro-2-quinazolinyl)carbonyl]benzoic acid. Salts of 5-and
6-alkyl-substituted isoquino[3,2-b]quinazolines are readily oxidized on boiling in nitrobenzene, which leads to aromatization
of the isoquino[3,2-b]quinazoline system to 5-methyl-13-oxo-5H,13H-isoquino[ 3,2-b]quinazolinium perchlorate and 6-benzyl-13H-isoquino[3,2-b]quinazolin-13-one.
The structures of the dehydrogenation products were established from 1H NMR and UV spectra. The interaction of the obtained compounds with NaBH4 has been studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1833–1840, December, 2007. 相似文献
20.
I. V. Ukrainets A. A. Tkach E. V. Mospanova E. N. Svechnikova 《Chemistry of Heterocyclic Compounds》2007,43(8):1014-1019
A preparative method has been developed for the synthesis of 1-hydroxy-3-oxo-5,6-dihydro-3H pyrrolo[3,2,1-ij]quinoline-2-carboxylic
acid hydrazide and its derivatives. The results of a study of the antitubercular activity of the synthesized compounds are
presented.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1196–1203, August, 2007. 相似文献