共查询到20条相似文献,搜索用时 5 毫秒
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M. Zh. Ovakimyan G. Ts. Gasparyan A. S. Bichakhchyan A. S. Pogosyan F. S. Kinoyan R. A. Tamazyan A. G. Aivazyan 《Russian Journal of General Chemistry》2014,84(6):1126-1129
Buta-1,3-diene-1,4-diylbis(triphenylphosphonium) iodide reacted with alkanethiols at room temperature in the presence of triethylamine to give [4-(alkylsulfanyl)buta-1,3-diene-1-yl]triphenylphosphonium iodides and triphenylphosphine in high yields. Two presumable reaction mechanisms involving ethynylvinyl intermediate (formed via the Hofmann decomposition of the starting diiodide and the initially formed 1,4-adduct with a thiol) were discussed. 相似文献
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I. M. Sakhautdinov I. R. Batyrshin A. A. Fatykhov F. Z. Galin M. S. Yunusov 《Russian Journal of Organic Chemistry》2012,48(6):793-798
Dimeric compounds formed as a result of thermal oligomerization of methyl 4-(1,3-dioxo-2,3- dihydro-1H-isoindol-2-yl)buta-2,3-dienoate were identified. 相似文献
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a one-step conversion of butyne-1,4-diol (1) to 2,3-di(phenylsulfinyl)-1,3-butadiene (4) and the conversion of this bis-sulfoxide to the sulfoxide-sulfone 6 and the bis-sulfone 5 are reported. 相似文献
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D. Bevk M. Kmetic S. Recnik J. Svete L. Golic A. Golobic B. Stanovnik 《Chemistry of Heterocyclic Compounds》2001,37(12):1498-1510
Ethyl (Z)-2-(2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)-3-(dimethylamino)propenoate was prepared in one step from ethyl (2,3-dihydro-1,3-dioxo-1H-isoindol-2-yl)acetate and bis(dimethylamino)-tert-butoxymethane and treated with various amines and hydrazines to afford the corresponding amino substituted products. Reactions of the titled compound with N,N'-, C,N-, and C,O'-ambident nucleophiles in refluxing acetic acid furnished the corresponding fused pyrimidinones, quinolizinones, and pyranones. 相似文献
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An approach for the total synthesis of 1,4-bis(2-(tert-butyl)-2H-tetrazol-5-yl)buta-1,3-diyne was reported. Developed approach to the synthesis of 1,4-bis(2-(tert-butyl)-2H-tetrazol-5-yl)buta-1,3-diyne can be used for obtaining different 2,5-bis(tetrazol-5-yl)-disubstituted five-membered heterocycles (e.g. thiophenes, pyrroles, furans etc.), as well as tetrazole-containing monomers for the synthesis of new types of electroconductive and high energetic polymers. 相似文献
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Koronatov Alexander N. Rostovskii Nikolai V. Khlebnikov Alexander F. Novikov Mikhail S. 《Chemistry of Heterocyclic Compounds》2019,55(12):1185-1189
Chemistry of Heterocyclic Compounds - A one-pot method for the synthesis of 3-(pyridin-2-yl)-2,3-dihydroazetes was developed on the basis of Rh2(esp)2-catalyzed reaction of diazoesters with... 相似文献
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2,3-Bis(5-tert-butyl-2-methoxyphenyl)buta-1,3-diene was prepared by bromination of (Z)- and (E)-2,3-bis(5-tert-butyl-2-methoxyphenyl)-2-butene followed by treatment with zinc powder in a mixture of CH2Cl2 and acetic acid, which was converted to the corresponding o-terphenyl skeleton by the condensation with dimethyl acetylenedicarboxylate followed by oxidation with 2,3-dichloro-5,6-dicyanobenzoquinone. 相似文献
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A. N. Gusev V. F. Shul’gin I. N. Shcherbakov K. A. Lysenko V. V. Minin I. L. Eremenko 《Russian Journal of Coordination Chemistry》2017,43(1):37-43
Two new copper(II) complexes with 1,3-bis(5-(pyridin-2-yl)-1,2,4-triazol-3-yl)propane (H2L), [Cu2(HL)Cl3] · H2O (I) and [Cu(H2L)](ClO4)2 (II), were described. The compounds were characterized by elemental analysis, IR spectroscopy, and magnetochemical data. According to X-ray diffraction data (CIF files CCDC nos. 1497511 (I), 1497512 (II)), complex I is binuclear and the metal cations are bound by the nitrogen atoms of the triazole ring and by the chloride anion. Complex II is mononuclear. Analysis of the temperature dependence of the magnetic susceptibility of I attests to the antiferromagnetic coupling of paramagnetic centers (–2J = 18 cm–1). Exchange channels are analyzed by means of density functional theory (B3LYP/6-311G(d)) using the broken symmetry approach. 相似文献
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4-(2-Hydroxybenzoyl)salicylic esters and amides were prepared by domino ‘Michael-Retro-Michael-Wittig’ reactions of (2,4-dioxobutylidene)triphenylphosphoranes with 3-formylchromones. 相似文献
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Bhatti BS Strachan JP Breining SR Miller CH Tahiri P Crooks PA Deo N Day CS Caldwell WS 《The Journal of organic chemistry》2008,73(9):3497-3507
In an attempt to generate nicotinic acetylcholine receptor (nAChR) ligands selective for the alpha4beta2 and alpha7 subtype receptors we designed and synthesized constrained versions of anabasine, a naturally occurring nAChR ligand. 2-(Pyridin-3-yl)-1-azabicyclo[2.2.2]octane, 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, and several of their derivatives have been synthesized in both an enantioselective and a racemic manner utilizing the same basic synthetic approach. For the racemic synthesis, alkylation of N-(diphenylmethylene)-1-(pyridin-3-yl)methanamine with the appropriate bromoalkyltetrahydropyran gave intermediates which were readily elaborated into 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane and 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane via a ring opening/aminocyclization sequence. An alternate synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane via the alkylation of N-(1-(pyridin-3-ylethylidene)propan-2-amine has also been achieved. The enantioselective syntheses followed the same general scheme, but utilized imines derived from (+)- and (-)-2-hydroxy-3-pinanone. Chiral HPLC shows that the desired compounds were synthesized in >99.5% ee. X-ray crystallography was subsequently used to unambiguously characterize these stereochemically pure nAChR ligands. All compounds synthesized exhibited high affinity for the alpha4beta2 nAChR subtype ( K i < or = 0.5-15 nM), a subset bound with high affinity for the alpha7 receptor subtype ( K i < or = 110 nM), selectivity over the alpha3beta4 (ganglion) receptor subtype was seen within the 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane series and for the muscle (alpha1betagammadelta) subtype in the 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane series. 相似文献
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Romanyuk A. L. Litvin B. L. Ganushchak N. I. 《Russian Journal of General Chemistry》2001,71(4):655-656
Russian Journal of General Chemistry - 相似文献
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An efficient synthesis of 3,3-di(1H-indol-3-yl)indolin-2-ones and 2,2-di(1H-indol-3-yl)-2H-acenaphthen-1-ones via a reaction of various isatins or acenaphthenequinone with indoles in the presence of p-methylbenzene sulfonic acid (p-TSA) in CH2Cl2 at room temperature is described. The advantages of this method include good reaction yield, simple workup procedure, and mild reaction condition. 相似文献
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Masakatsu Matsumoto Naoyuki Hoshiya Ryo Isobe Yukie Watanabe Nobuko Watanabe 《Tetrahedron letters》2004,45(20):3895-3898
2-(Buta-1,3-dienyl)-3-methylpyrazines (5) and 3-(buta-1,3-dienyl)-4-methyl-1,2,5-oxadiazoles (10) were synthesized starting from base-induced reaction of 2,3-dimethylpyrazine or 3,4-dimethyl-1,2,5-oxadiazole with α,β-unsaturated carbonyls. The thus obtained heteroaromatics bearing a butadienyl moiety and a methyl at the adjacent position underwent intramolecular cyclization by the action of LDA to give the corresponding heteroaromatics fused with a seven-membered ring [7 (8)] and [11 (12)] in moderate to high yields. 相似文献