Chemical composition of the essential oil ofArtemisia glabella

The results are given of the gas-chromatographic analysis in a nonpolar capillary column, after preliminary separation by means of adsorption chromatography on alumina, of samples of the essential oils of three populations of the endemic speciesArtemisia glabella Kar. et Kir. (Asteraceae) of Kazakhstan. The complex component composition of the samples of essential oils was practically independent of the conditions of the growth site. The results obtained witness a chemosystematic difference betweenA. glabella andA. obtusiloba.Institute of Phytochemistry, Academy of Sciences of the Republic of Kazakhstan, Karaganda, fax (3212) 433144, e-mail: arglabin@phyto.karaganda.su. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 193–196, March–April, 1999.     

Chromatographic study of the composition of the essential oil ofZiziphora clinopodioides, a vicarious form ofOriganum vulgare

The chemical composition of the essential oil ofZiziphora clinopodioides has been studied by GLC. A similarity of the qualitative compositions of the terpenoids of the essential oils ofZ. clinopodioides and other species of this genus has been shown.Institute of Phytochemistry, Academy of Sciences of the Republic of Kazakhstan, Karaganda, fax (3212) 51 10 23. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 66–68, January–February, 1999.     

Comparative chromatographic study of the sesquiterpenes of someTanacetum species

A comparative qualitative and quantitative analysis has been made by the HPLC method of the sesquiterpene lactones of various fractions obtained from the epigeal pans of three species of tansy,Tanacetum L., growing in Kazakhstan. Five of seven standard lactones have been identified and it has been shown that the amount of each lactone varies within wide limits both in individual fractions and in differentTanacetum species.Institute of Phytochemistry, National Academy of Sciences, Republic of Kazakhstan, Karaganda, fax (3212) 51 10 23. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 875–878, November-December, 1996. Original article submitted April 1, 1996.     

Synthesis of monoesters ofD-sorbitol and aromatic acids

Water-soluble monoesters ofD-sorbitol with aromatic acids have been synthesized by the transesterification of their methyl esters. The structures of the compounds obtained have been confirmed by IR, UV, and¹³C NMR spectroscopies.A. B. Bekturov Institute of Chemical Sciences, Academy of Sciences of the Republic of Kazakhstan, Almaty [Alma-Ata], ul. Sh. Ualikhanova, 106, fax 61 57 65. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 735–737, September–October, 1997.     

Components of <Emphasis Type="Italic">Artemisia pontica</Emphasis>

Chemical components from the aerial part of the Kazakhstan population of Artemisia pontica, from which the rarely encountered flavonoids 7-O-methyl- and 4′,7-di-O-methyl-esters of apigenin were isolated for the first time, were identified. The complete chemical composition of the essential oil was established using GC-MS.__________Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 143–145, March–April, 2005.     

Chemical composition of the essential oils ofZiziphora growing under various ecological conditions

It has been established that, in spite of different ecological conditions of the growth of the endemic speciesZiziphora vychodceviana, Z. pedicellata, andZ. persica, they are characterized by identical biosyntheses of terpenoids and differ by the ratio of the main components of their essential oils.Institute of Chemical Sciences, National Academy of Sciences, Republic of Kazakhstan, Alma-Ata. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 727–729, November–December, 1994.     

Synthesis and antioxidant activity of phenolic derivatives ofα-santonin

Phenolic derivatives of-santonin have been synthesized and their antioxidant effect has been studied.Institute of Phytochemistry, National Academy of Sciences of the Republic of Kazakhstan, Karaganda. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 247–249, March–April, 1997.     

A new terpene ketone, a component of the essential oil ofElsholtzia ciliata

A new terpene ketone which has been called dehydroelsholtsia ketone has been isolated from the essential oil ofElsholtzia ciliata (Thumb.) Hyl. The structure of dehydroelsholtzia ketone as 3-methyl-2-(3-methylbut-2-enoyl)furan has been proposed on the basis of a study of its IR, PMR, mass and¹³C spectra and has been confirmed by its conversion into elsholtzia ketone.Institute of Chemical Sciences, Academy of Sciences of the Republic of Kazakhstan, Alma-Ata. Siberian State Medical Institute, Tomsk. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 823–824, November–December, 1993.     

Stereoselective hydrogenation of 11-hexadecyne-l-ol on supported copper catalysts

Hydrogenation of 11-hexadecyne-l-ol on 5–30 % copper catalysts supported on -A1₂O₃ and MgCO₃ results incis-11-hexadecyne-1-ol in 100 % yield. Hydrogenation does not occur on 5–30 % Cu/ZnO catalysts. The difference in behavior of the catalysts is connected with the valent state of copper on the surface and different hydrogen chemisorption.Positive conclusion on the application No. 930071.1 of 16.06.93 for the Kazakhstan preliminary Patent (A. M. Pak, O. 1. Kartonozhkina, and G. T. lzdebskaya).Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1147–1150, May, 1996.     

Phenolic compounds of a culture ofAlhagi kirghisorum cells

A comparative analysis has been made of a series of phenolic compounds in the initial plant and in a cell culture ofAlhagi kirghisorum. Quercetin, isorhamnetin, isorhamnetin 3-O-neohesperoside, retusin, 8-methylretusin, calycosin and formononetin were isolated from the cultivated cells and identified. Features of the formation of various classes of phenolic compounds in the cultivated cells have been studied by chromatographic methods. It has been shown that the phenolic substances synthesized by cell cultures exhibit an inhibiting influence on the biosynthesis of protein in vitro and show a moderate cytotoxic activity.M. A. Aitkhozhin Institute of Molecular Biology and Biochemistry, Academy of Sciences of the Republic of Kazakhstan, fax 8-3272-347091. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 182–184, March–April, 1999.     

Molecular structure of crepidioside a and isolipidiol fromCrepis multicaulis

Crepidioside A, a guaian-like sesquiterpene lactone, is isolated fromCrepis multicaulis Ldb, and identified. The structure 15-glycoside-2-oxo-5,7,6(H)-guai-1(10),3(4),11(13)-trien-6,12-olide is found from an x-ray structure analysis. 8-Epi-isolipidiol is isolated fromCrepis tectorum L. Its new polymorphic crystal structure is found from an x-ray structure analysis.Institute of Phytochemistry, Ministry of Science and Higher Education, Republic of Kazakhstan, fax (3212) 43 37 73, Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 139–141, March–April, 2000.     

Structure of the Z,Z-Germacranolide 1(10)Z,4Z-Hanphyllin

The spatial structure of 1(10)Z, 4Z-hanphyllin has been established by the x-ray method. A new conformation of the ten-membered ring in Z, Z-germacranolides has been found - the₁₅ D ₅,₁ D ₁₄ boat-boat type. The probabilities of the realization of the conformers of this compound and of its C3-epimer have been calculated by the method of molecular mechanics.Institute of Organic Synthesis and Coal Chemistry, National Academy of Sciences of the Republic of Kazakhstan, 470061, Karaganda, ul. 40 let Khazakhstana, 1. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 50–53, January February, 1996. Original article submitted August 14, 1995.     

Modifications based on coumarins I. Synthesis of monoesters of karatavikic and galbanic acids with sucrose

The synthesis has been achieved of water-soluble 6-O-monoesters of sucrose with natural coumarins — karatavikic and galvanic acids — by the transesterifacation of their methyl esters with sucrose. The structures of the compounds obtained have been confirmed by IR, UV, PMR, and¹³C NMR spectroscopies.A. B. Bekturov Institute of Chemical Sciences, National Academy of Sciences, Republic of Kazakhstan, Almaty, fax 61 57 65. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 541–544, July–August, 1996. Original article submitted January 30, 1996.     

Modifications based on coumarins. II. Synthesis ofα-monoglycerides of karatavic and galbanic acids and their phosphates

The synthesis has been performed of -monoglyceride derivatives of coumarins — karatavic and galbanic acids and their modified derivatives — phosphates. The structures of the compounds have been confirmed by IR, UV, PMR, and¹³C and³¹P NMR spectroscopies.A. B. Bekturov Institute of Chemical Sciences, Academy of Sciences of the Republic of Kazakhstan, Almaty Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 217–220, March–April, 1997.     

Stereochemistry, absolute configuration, and crystal structure ofcis-(4S,9S,10R)-1-(S-1-phenylethyl)decahydroquinolin-4-ol. Relative stereochemistry of cycloalkano-2,3-piperidin-4-ols

According to x-ray crystallographic data, thecis-isomer of 1-(1-phenylethyl)decahydroquinolin-4-ol, the predominant product of the stereoselective hydrogenation of1-(1--phenylethyl)-^{9, 10} -octahydroquinoline-4-one with sodium tetrahydroborate, has the (4S, 9S, 10R) configuration. The x-ray crystallographic data for this cisdecahydroquinolin-4-ol have been compared with the previously studied piperidin-4-ones of known absolute configuration. The stereochemical rules for cycloalkano-2,3-piperidine-4-ols are discussed.M. V. Lomonosov Moscow State University, Chemistry Faculty, Moscow 119899, A. N. Nesmeyanov Institute of Elementoorganic Chemistry, Russian Academy of Sciences, Moscow 117813. A. B. Bekturov Institute of Chemical Science, Kazakhstan Academy of Sciences, Alma-Ata 480100. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 526–534, April, 1998.     

Synthesis of a monoester of sucrose with trans-O-methylmarmesinic acid

The water-soluble 6-O-monoester of sucrose with trans-O-methylmarmesinic acid has been synthesized by the transesterification of methyl trans-O-methylmarmezinate with sucrose, The structure of the compound obtained has been confirmed by UR, UV, PMR, and¹³C NMR spectroscopies.Institute of Chemical Sciences, Kazakhstan Republic Academy of Sciences, Alma-Ata. Translated from Khimiya Prirodnykh Soedeninii, No. 1, pp. 100–103, January–February, 1993.     

Mechanism and kinetics of the hydrogenation of CO to saturated hydrocarbons and alcohols on supported bimetallic catalysts containing rhodium

The mechanism of the simultaneous formation of methane, ethane, propane, methanol, ethanol, and propanol from carbon monoxide and hydrogen over supported bimetallic catalyst, Rh-M/Al₂O₃, has been established on the basis of kinetic and adsorption data. The experimental data are described quantitatively by kinetic and thermodynamic parameters calculated using the kinetic model.L. V. Pisarzhevskii Institute of Physical Chemistry, Ukraine National Academy of Sciences, Ukraine, 252039 Kiev, Nauki Prosp. 31. D. V. Sokol'skii Institute of Organic Catalysis and Electrochemistry, Kazakhstan National Academy of Sciences, Kazakhstan, 480110 Alma Ata, D. Kunaev Street, 142. Translated from Teoreticheskeskaya i Éksperimental'naya Khimiya, Vol. 32, No. 2, pp. 97–101, March–April, 1996. Original article submitted May 23, 1995.     

Chemical composition of a CO2 extract of rose fruit

The chemical composition and physicochemical characteristics of a CO₂ extract of rose fruit have been studied. It was established that the main component of the extract consisted of lipids, and the class and fatty-acid compositions of these are given.Almaty Pharmaceutical Factory Company Limited, 480008, Republic of Kazakhstan, Almaty, ul. Shevchenko, 162-E, fax 42 96 75. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 880–882, November–December, 1997.     

Synthesis of α-monoglycerides of aromatic acids

The synthesis of -monoglycerides of aromatic acids has been performed by the transesterification of the methyl esters of the corresponding acids with glycerol. The structures of the compounds obtained have been confirmed by their IR, UV, and¹H and¹³C NMR spectra.A. B. Bekturov Institute of Chemical Sciences, Academy of Sciences of the Republic of Kazakhstan, Almaty, fax (3272) 61 57 65. Translated from Khimiya Prirodnykh Soedineii, No. 4, pp. 452–457, July–August, 1999.     

Blue-shifted hydrogen-bonded complexes. II. CH3F(HF)1 n 3 and CH2F2(HF)1 n 3

The equilibrium structures, binding energies, and vibrational spectra of the clusters CH₃F(HF)_{1 n 3} and CH₂F₂(HF)_{1 n 3} have been investigated with the aid of large-scale ab initio calculations performed at the Møller–Plesset second-order level. In all complexes, a strong C–FH–F halogen–hydrogen bond is formed. For the cases n = 2 and n = 3, blue-shifting C–HF–H hydrogen bonds are formed additionally. Blue shifts are, however, encountered for all C–H stretching vibrations of the fluoromethanes in all complexes, whether they take part in a hydrogen bond or not, in particular also for n = 1. For the case n = 3, blue shifts of the ν(C–H) stretching vibrational modes larger than 50 cm⁻¹ are predicted. As with the previously treated case of CHF₃(HF)_{1 n 3} complexes (A. Karpfen, E. S. Kryachko, J. Phys. Chem. A 107 (2003) 9724), the typical blue-shifting properties are to a large degree determined by the presence of a strong C–FH–F halogen–hydrogen bond. Therefore, the term blue-shifted appears more appropriate for this class of complexes. Stretching the C–F bond of a fluoromethane by forming a halogen–hydrogen bond causes a shortening of all C–H bonds. The shortening of the C–H bonds is proportional to the stretching of the C–F bond.