共查询到20条相似文献,搜索用时 109 毫秒
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3-杂环基硫取代-1,3,4,5-四氢-2-氧代-苯并氮杂衍生物的合成 总被引:1,自引:0,他引:1
以芳酰肼为原料,合成了一系列3-巯基-5-芳基-1,2,4-三唑、2-巯基-5-芳基-1,3,4-噁二唑和2-巯基-5-芳基-1,3,4-噻二唑,并通过硫原子对3-溴-2-氧代-苯并氮杂3-位上的亲核取代反应将杂环化合物引入了苯并氮杂的结构当中,合成了32个新的苯并氮杂杂环衍生物.为提高其在有机溶剂中的溶解性,在苯并氮杂的N原子上引入乙酸乙酯和乙酸叔丁酯基取代基,合成了36个新衍生物.所有化合物经质谱、核磁共振谱及元素分析确证了结构并初步测定了抗菌活性. 相似文献
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以芳酰肼为原料, 合成了一系列3-巯基-5-芳基-1,2,4-三唑、2-巯基-5-芳基-1,3,4-噁二唑和2-巯基-5-芳 基-1,3,4-噻二唑, 并通过硫原子对3-溴-2-氧代-苯并氮杂3-位上的亲核取代反应将杂环化合物引入了苯并氮杂的结构当中, 合成了32个新的苯并氮杂杂环衍生物. 为提高其在有机溶剂中的溶解性, 在苯并氮杂的N原子上引入乙酸乙酯和乙酸叔丁酯基取代基, 合成了36个新衍生物. 所有化合物经质谱、核磁共振谱及元素分析确证了结构并初步测定了抗菌活性. 相似文献
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卤素及三卤甲基侧取代大杂环化合物的结构和性能——Ⅱ.氧、氮、硫杂大环化 总被引:1,自引:0,他引:1
用AM1方法计算了20个卤素及三卤甲基侧取代氧、氮、硫杂大环化合物的电子结构。结果表明,这类杂环化合物分子的总能量,最高占据分子轨道能量,杂环中氧、氮、硫原子的电荷分布和空腔大小呈现出一定的规律性。它们对于络合过渡金属具有较强的选择性。 相似文献
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《结构化学》2019,38(10)
In this paper, a new Pd-based complex that contains N-heterocyclic carbene(NHC) and triphenylphosphine(PPh3) ligands was synthesized. The cis-(NHC)Pd Br_2(PPh3) complex has been prepared by the substitution of 3-chloropyridine ligand in(NHC)PdBr_2(3-chloropyridine) complex with triphenylphosphine. This complex has been characterized by using ~1H NMR, 31 P {~1H} NMR, ~(13)C {~1H} NMR, FTIR, UV-Vis spectroscopy and elemental analysis techniques. The molecular and crystal structures of the cis-(NHC)PdBr_2(PPh3) complex were determined by singlecrystal X-ray diffraction method. 相似文献
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James P. Bloxsidge John A. Elvidge John R. Jones E. Anthony Evans J. Philip Kitcher David C. Warrell 《Magnetic resonance in chemistry : MRC》1981,15(2):214-217
The complete analysis of the tritium distribution in tritiated methyl groups in labelled compounds is achieved by a direct method for the first time, through 3H NMR spectroscopy aided by resolution enhancement. 相似文献
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Two novel fluorescent calix[4]arene derivatives 1a and 1b with benzoxazole or benzothiazole units in 1,3-alternate conformation have been synthesized and characterized by IR,~1H NMR,~(13)C NMR and MS.Their complexation properties to different heavy and transition metal ions have been studied by UV-vis spectroscopy and fluorescence spectrometer.Compounds 1a and 1b show selective recognition to Fe~(3+) and Cr~(3+). 相似文献
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Lu Zhang Juan Du Li Hua Yuan Dong Zhang Gui Ping Dan Yuan You Yang Wen Feng 《中国化学快报》2011,22(3):284-287
A series of novel calix[4]arenecrown-6 derivatives with an alkenyl loop of various sizes 5-8 were synthesized via intramolecular ring closing olefin metathesis and characterized by ~1H NMR,~(13)C NMR and ESI-HRMS.Their complexation property towards cesium ion was studied by ~1H NMR technique.Two-phase extraction of alkali metal ions using UV-vis spectroscopy revealed remarkably different extractabilities.These results indicate that the complexation capacities towards cesium ions can be tuned and controll... 相似文献
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稀土与四甘醇醛缩苯丙氨酸Schiff碱配合物的合 成、性能与催化 总被引:3,自引:0,他引:3
合成了直链醚-氨基酸新型Schiff碱(四甘醇醛缩苯丙氨酸Schiff碱)及其与稀土新配合物,[Ln~3L~2(NO~3)~2]·(NO~3)~3·nH~2O(Ln=La,Nd,Sm,n=3;Ln=Gd,Dy,Er,Y,n=5),以元素分析、磁化率、红外光谱、^1HNMR等进行了表征,研究了的配位作用,根据预期设想,见到此类配合物在有机溶剂中的溶解性有明显改善。以EPR波谱探讨了配合物的晶体场强,并计算了晶体场参数。此外,发现在不加助催化剂条件下,此类配合物对MMA(甲基丙烯酸甲酯)聚合有一定的催化效果。 相似文献
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磺酰脲类除草剂具有用量低,活性高、选择性好、毒性小的优点。为开发和应用此类除草剂,我们合成了在氮原子上连正丁基的8个新的衍生物,并进行了室内药效测定。 相似文献
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An array of NMR spectroscopy experiments have been carried out to obtain conformationally dependent (1)H,(13)C- and (13)C,(13)C-spin-spin coupling constants in the trisaccharide α-L-Rhap-(1 → 2)[α-L-Rhap-(1 → 3)]-α-L-Rhap-OMe. The trisaccharide was synthesized with (13)C site-specific labeling at C2' and C2″, i.e. in the rhamnosyl groups in order to alleviate (1)H spectral overlap. This facilitated the measurement of a key trans-glycosidic proton-proton cross-relaxation rate using 1D (1)H,(1)H-T-ROESY experiments as well as a (3)J(C, H) coupling employing 1D (1)H,(13)C-long-range experiments, devoid of potential interference from additional J coupling. By means of both the natural abundance compound and the (13)C-labeled sample 2D (1)H,(13)C-J-HMBC and (1)H,(13)C-HSQC-HECADE NMR experiments, total line-shape analysis of (1)H NMR spectra and 1D (13)C NMR experiments were employed to extract (3)J(C, H) , (2)J(C, H), (3)J(C, C), and (1)J(C, C) coupling constants. The (13)C site-specific labeling facilitates straightforward determination of (n)J(C, C) as the splitting of the (13)C natural abundance resonances. This study resulted in eight conformationally dependent coupling constants for the trisaccharide and illustrates the use of (13)C site-specific labeling as a valuable approach that extends the 1D and 2D NMR methods in current use to attain both hetero- and homonuclear spin-spin coupling constants that subsequently can be utilized for conformational analysis. 相似文献