Molecular Encapsulation of Half-Sandwich Complexes of Iron with Cyclodextrins: New Laminar Materials

The treatment of - and -cyclodextrins with the half-sandwich complexes of iron afford the inclusion compounds CpFe(L₂)XCD ( and ) (X = Cl, I; L = CO; L₂ = dppe, dppe = (Ph)₂P(CH₂)₂P(Ph)₂), [CpFe(L₂)L-]PF₆CD ( and ) L- neutral donor ligands and[(Cp(dppe)Fe)₂-µ-CN]PF₆2CD ( and ). The inclusion compounds [Cp(dppe)Fe-NCCH₃]PF₆-CD and [Cp(dppe)Fe-(¹-dppm)]PF₆-CD have a laminar structure. The - and -cyclodextrin encapsulation effect on the electro-oxidation of the binuclear complex was studied using cyclic voltammetry.The electron-transfer reactions associated with the oxidation of the two different N-bonded and C-bonded organometallic fragments are substantially affected by and encapsulation.     

Magnetic microspheres for targeting of drugs

Magnetic microspheres were prepared from starch. The microspheres could be crosslinked with various agents, and drugs could be entrapped adsorbed, or covalently coupled to the microspheres.     

药物输送体系构筑中的超分子组装策略

超分子组装提供了药物输送体系设计的新原理。以高效的分子间非共价键作用为驱动力,超分子药物输送体系能够利用结构简单的分子单体获得精确的成分控制,并使得载体结构易于预测,形貌与体积易于调控,有利于实现药物的控制释放。本文首先总结超分子药物输送体系的研究背景,之后重点介绍基于环糊精、杯芳烃、柱芳烃和葫芦脲的主-客体体系的超分子药物输送体系的构建与药物输送功能,然后介绍水溶性的超分子有机框架在药物输送方面的应用,最后提出了超分子药物载体实用化需要克服的若干挑战性问题。     

The Exceptional Diversity of Homoleptic Uranium–Methyl Complexes

Homoleptic σ-bonded uranium–alkyl complexes have been a synthetic target since the Manhattan Project. The current study describes the synthesis and characterization of several unprecedented uranium–methyl complexes. Amongst these complexes, the first example of a homoleptic uranium–alkyl dimer, [Li(THF)₄]₂[U₂(CH₃)₁₀], as well as a seven-coordinate uranium–methyl monomer, {Li(OEt₂)Li(OEt₂)₂UMe₇Li}_n were both crystallographically identified. The diversity of complexes reported herein provides critical insight into the structural diversity, electronic structure and bonding in uranium–alkyl chemistry.     

The character of interaction of organometallic derivatives of 4-nitrophenol and 4-nitrothiophenol with anions in different media

Interaction of R _n M-derivatives of 4-nitrophenol and thiophenol (R _n M= PhHG, PPh₃Au, Ph₃Sn, Ph₄Sb) with a set of inorganic and organic anions (Cl^–, Br^–, I^–, CN^–, [PhOCO]^–, [4-NO₂C₆H₄OCO]^–) was studied by IR and electronic spectroscopy in solvents with different polarities and coordinating properties (C₆H₆, CH₂Cl₂, DMSO). The dependence of the character of the interaction with the anions on the nature of the metal atom and heteroatom, the type of anions and the nature of the media was analyzed. Such interaction leads to ion-molecular complexes, and also to dissociation of the X-M bond (X = O, S, M = Au, Hg. Sb) with formation of the (4-NO₂C₆H₄X)^– anion even in weakly polar media. Only in the case of 4-NO₂C₆H₄OSnPh₃ does the reaction stop at the stage of complex formation. In other cases the role of complex formation with anions is less than with neutral coordinating reagents.Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 7, pp. 1838–1841, July, 1996.     

介绍一种金属有机化合物的分类新方法: 共价键分类法

本文比较详细地介绍了M.L.H.Green最近提出的金属有机化合物分类新方法-共价键分类法,包括基本概念、MLX丰度图的绘制及其在提供金属的反应性与反应机理等信息方面的应用。