一种新型卟啉-脂质体衍生物的合成及表征

采用人工合成的N,N-二.十六烷基-6-溴代-L-甘氨酰胺(BrC5Gly2C16H33)与5,10,15-三苯基-20-对羟基苯基卟啉(HPTPP)相连接,合成了一种新型卟啉-脂质体衍生物(P-L),用元素分析、紫外可见光谱、核磁共振、红外光谱以及荧光光谱等方法进行了表征,并对其谱学性质进行了研究.     

齐聚噻吩衍生物在溶液中的光物理和电化学性质

The photophysical and electrochemical properties of a family of oligothiophene derivatives in solution werestudied.It was found that the cyano and the vinyl group could increase fluorescence yield in solution,while theformyl and carboxyl group could decrease energy gap.With increasing the chain length of thiophene ring,the oxi-dation potential could be decreased.     

几种对称镍卟啉配合物的合成、表征和电化学性质

卟啉试剂是一类重要的离子配位显色剂,在生物体中具有重要作用．作为自然界存在的金属卟啉之一,镍卟啉的电化学研究具有化学和生物学意义．四对羟基苯基卟啉合成已有不少报道［１,２］,但产率较低,只有１０％左右．Ｌｉｎｄｓｅｙ等发现用ＢＦ３作催化剂,在ＣＨ２Ｃ...     

新型桥连双卟啉化合物的合成及结构表征

通过将4,4′-二羧基-2,2′-联吡啶、2,6-二溴甲基吡啶、2,6-二羟甲基吡啶和1,8-二氨基萘分别与5-(4-羟基苯基)-10,15,20-三苯基卟啉(1a)、5-(4-甲酰苯基)-10,15,20-三苯基卟啉(1b)和5-[4-(4′-溴代丁氧基)苯基]-10,15,20-三苯基卟啉(1c)反应,合成了3类新型的双卟啉化合物2a-2e,经IR,¹HNMR,MS,UV-Vis光谱及元素分析对中间体和目标化合物的结构进行了表征.     

双脂肪胺钌卟啉的合成、结构表征和晶体结构

本文讨论了一系列双脂肪胺钌卟啉配合物，包括Ru(^Ⅱ)(Por)(H₂NR)₂和Ru(^Ⅱ)(Por)(HNR₂)₂［Por=四苯基卟啉(TPP)，中位-四(对甲苯基)卟啉(TTP)，中位-四(对氯苯基)卟啉(4-Cl-TPP);R=叔丁基，异丙基，环己基，正辛基，正十二烷基，R′=甲基和乙基］的合成，结构表征和晶体结构测定。钌羰基卟啉与间-氯过苯甲酸的反应混合物用过量的脂肪胺处     

基于卟啉衍生物红光材料的合成及物性研究

利用Schiff base反应合成了两个卟啉衍生物TPP-AQ, TPP-PD. 通过循环伏安、紫外可见吸收光谱、荧光光谱及理论计算等对其物性进行了研究. 结果显示: TPP-AQ, TPP-PD氧化电位分别为E_1/2＝1.07, 1.30 V和1.21, 1.36 V, 与TPP-PD相比, TPP-AQ的两个氧化还原电位都发生了负移|TPP-AQ与TPP-PD的最大紫外可见吸收峰分别在441和431 nm, TPP-AQ的吸收波长较TPP-PD有一定程度的红移, 通过理论计算可知这是由于TPP-AQ共轭程度优于TPP-PD导致的. TPP-AQ和TPP-PD的荧光主发射峰分别在657和656 nm, 半峰宽分别为30和27 nm, 有较好的红光色纯度.     

卟啉及其衍生物合成进展

按卟啉母核的不同合成方法,介绍了卟啉衍生物的合成进展。从各种小分子的缩合而合成卟啉的方法包括经典的Alder-Long法、Lindsey法和新颖的[2＋2]法、[3＋1]法。这些方法能够合成许多结构复杂的卟啉。对卟啉大分子进行β-、meso-位功能团的引入,有卤代、硝化、甲酰化等,并能进一步转化成其它功能团。     

几种稀土卟啉配合物的固相合成及电化学性质研究

在固相条件下合成了４种四（对甲氧基苯基）卟啉稀土（Ｌｎ＝Ｌａ＾３＋,Ｐｒ＾３＋,Ｎｄ＾３＋,Ｄｙ＾３＋）配合物。用元素分析、ＩＣＰ、ＵＶ及ＩＲ光谱进行表征,用循环伏安法研究了它们的电化学性能,实验结果表明,它们的电化学性质相似。在循环伏安图中出现了三对氧化还原峰。第一对为「Ｃ４８Ｈ３６Ｎ４Ｏ４Ｌｎ（Ⅲ）」＾＋／「Ｃ４８Ｈ３６Ｎ４ＯＬｎ（Ⅱ）」,第二为「Ｃ４８Ｈ３６Ｎ４Ｏ４Ｌｎ（Ⅱ）」／「Ｃ４８Ｈ３６Ｎ４Ｏ４Ｌｎ（Ⅰ）」＾－１,第三对为「Ｃ４８Ｈ３６Ｎ４ＯＬｎ（Ⅰ）」＾－／「Ｃ４８Ｈ３６Ｎ４ＯＬｎ」＾２－。     

钌卟啉轴向配合物的合成与结构表征

采用一种简单的合成方法, 以钌羰基卟啉(1)和二氧钌卟啉(2)为原料, 与不同的氨基酸酯作用, 得到系列单氨基酸酯羰基和双氨基酸酯为轴向配体的钌卟啉配合物(4a~4c和5a~5d). 所有化合物均经过红外光谱、 核磁共振谱和质谱等表征手段确证为目标化合物, 并用X射线单晶衍射测定了化合物4a的分子结构, 这对研究钌卟啉与生物大分子的相互作用具有重要的意义.     

乙炔二茂铁的合成表征和电化学性质测定

选择了一条反应条件温和且比较经济的反应途径,在惰性气氛中合成了一系列二茂铁衍生物的重要合成中间体——乙炔二茂铁。通过UV、IR、^1H NMR对化合物进行了表征,运用CV测定了电化学性质。该实验作为综合化学实验,有助于学生了解化学研究的一般过程,掌握惰性气氛合成技术及柱色谱分离方法,提高学生综合分析问题和解决问题的能力。     

Synthesis of Novel Porphyrin Derivatives with Mesogenic Properties

Two novel porphyrin derivatives, 5,10,15,20-tetra(4-(N-octane-carboxamide)phenyl)porphyrin (4NC₈-TPP) and 5,10,15,20-tetra(4-(N-stearyl-carboxamide)phenyl)porphyrin (4NC₁₈-TPP), were synthesized. Their molecular structures were characterized by means of time-of-flight mass spectrometer (TOF-MS), nuclear magnetic resonance (NMR), and infrared spectra (IR). The thermal behavior and morphologies of 4NC₈-TPP and 4NC₁₈-TPP were examined by thermal gravity (TG), differential scanning calorimetry (DSC), x-ray diffraction (XRD), and polarizing optical microscope (POM). It was found that both 4NC₈-TPP and 4NC₁₈-TPP had mesogenic properties.     

可能用于光动力诊疗的2-硝基咪唑卟啉衍生物的合成及表征

从吡咯和对羟基苯甲醛等起始原料出发,设计合成了4种具有潜在肿瘤乏氧检测及光动力治疗作用的2-硝基咪唑修饰新型卟啉衍生物.目标化合物结构经紫外、红外、质谱和核磁确证.     

Flavin Derivatives with Tailored Redox Properties: Synthesis,Characterization, and Electrochemical Behavior

This study establishes structure–property relationships for four synthetic flavin molecules as bioinspired redox mediators in electro‐ and photocatalysis applications. The studied flavin compounds were disubstituted with polar substituents at the N1 and N3 positions (alloxazine) or at the N3 and N10 positions (isoalloxazines). The electrochemical behavior of one such synthetic flavin analogue was examined in detail in aqueous solutions of varying pH in the range from 1 to 10. Cyclic voltammetry, used in conjunction with hydrodynamic (rotating disk electrode) voltammetry, showed quasi‐reversible behavior consistent with freely diffusing molecules and an overall global 2e^?, 2H⁺ proton‐coupled electron transfer scheme. UV/Vis spectroelectrochemical data was also employed to study the pH‐dependent electrochemical behavior of this derivative. Substituent effects on the redox behavior were compared and contrasted for all the four compounds, and visualized within a scatter plot framework to afford comparison with prior knowledge on mostly natural flavins in aqueous media. Finally, a preliminary assessment of one of the synthetic flavins was performed of its electrocatalytic activity toward dioxygen reduction as a prelude to further (quantitative) studies of both freely diffusing and tethered molecules on various electrode surfaces.     

新型不对称卟啉配体及其锌配合物的合成与荧光性能

以3,5-二羟基苯甲酸丙酯和5-(4-硝基)苯基-10,15,20-三苯基卟啉为起始原料,合成了新型的不对称卟啉配体——5-[4-(3,5-二-十六烷氧基苯甲酰亚胺基)苯基]-10,15,20-三苯基卟啉(1)及其锌配合物(2),其结构经UV-Vis,1H NMR,IR和元素分析表征。用荧光激发光谱研究了1和2的荧光性能,结果表明:在激发波长为420 nm时,1和2的荧光发射峰分别在650 nm,709 nm和600 nm,644 nm。     

Synthesis, Characterization, and Electrochemical Property of Nanometer Porphyrin Dimer

A nanometer porphyrin dimer was synthesized with fumaryl chloride as a bridge-linked reagent. The characterization was carried out with elemental analyses, ^1H NMR, UV-Vis, and IR spectrometries, and then the electrochemical properties of the porphyrins were studied. The authors found that there was moderate electronic communication between the two porphyrin rings in the nanometer porphyrin dimer.     

A New 3-D Lanthanide Porphyrin: Synthesis,Structure and Photophysical Properties

A new lanthanide porphyrin, [Sm III(H3TPPSIII)]n·n H2O(1, H6 TPPS = tetra(4-sulfonatophenyl)porphyrin), has been synthesized through a hydrothermal reaction and structurally characterized by single-crystal X-ray diffraction. Compound 1 crystallizes in the P4/mcc space group of tetragonal system: a = 15.3683(12), c = 9.895(2) A, V = 2337.0(5) A3, C44H29N4O13S4 Sm, Mr =1100.30, Z = 2, Dc = 1.564 g/cm3, S = 1.063, μ(Mo Kα) = 1.502 mm–1, F(000) = 1102, R = 0.0583 and w R = 0.1666. Compound 1 is characteristic of a three-dimensional(3-D) framework with a slightly distorted square-antiprism eight-coordinated Sm3+ ion. Fluorescent study revealed that compound 1exhibits an emission in the red region. The fluorescence quantum yield and lifetime of 1 were determined to be 3.5% and 9.1 ns, respectively. UV-vis absorption spectra were also investigated.     

新型卟啉及其锌配合物的合成与性质研究

设计合成了一种新型的不对称卟啉(5,10,15-三苯基-20-{4-[6′-(4″-o-亚水杨基)-苯亚胺基]己氧基}苯基卟啉)及其锌配合物,并用¹H NMR、质谱及紫外-可见光谱进行表征。采用紫外-可见光谱滴定法,对锌卟啉与4种咪唑类小分子间的轴向配位反应热力学性质的研究表明：反应为放热、熵增加过程,4种咪唑类配体对锌卟啉的配位平衡常数按K^Θ(2-MeIm)>K^Θ(N-MeIm)>K^Θ(2-Et-4-MeIm)>K^Θ(Im)顺序依次减小。运用Z-扫描技术研究了新型卟啉及其锌配合物的非线性光学性质。