共查询到20条相似文献,搜索用时 234 毫秒
1.
Three cyclodextrine derivatives (6A,6D-di-O-(prop-2-one-1,3-dienyl)-alpha-cyclodextrin (1), 6-O-(prop-2-one-1-yl)-alpha-cyclodextrin (2) and 6A,6D-di-O-(prop-2-one-1,3-dienyl)-beta-cyclodextrin (3)) were synthesised and investigated as epoxidation catalysts. The three compounds were synthesised from the corresponding perbenzylated cyclodextrins which were mono- or didebenzylated in the 6-position using Sina?'s method. Reaction with NaH and methallyl chloride in the case of 2, or methallyl dichloride in the case of 1 and 3, followed by dihydroxylation, periodate cleavage and protection group removal gave the target compounds. All three compounds catalysed, in the presence of oxone, the epoxidation of a series of alkenes. Epoxidation was compared to the reaction catalysed by simple ketones and inhibition was studied. 相似文献
2.
A study is made of the epoxidation of hepten-2-one-4, octen-3-one-5, nonen-4-one-6, 2-methylhepten-5-one-4, 2-methylocten-5-one-4, and 2-methylnonen-5-one-4 with alkaline methanolic hydrogen peroxide. 46–71% yield of the corresponding epoxy ketones are obtained. It is shown that treatment of the 2, 3-epoxyheptanone-4, 3, 4-epoxyoctanone-5, 4, 5-epoxynonanone-6, 2-methyl-5, 6-epoxyheptanone-4, 2-methyl-5, 6-epoxyoctanone-4 and 2-methyl-5, 6-epoxynonanone-4 with zinc chloride isomerizes them to, respectively, heptandione-3, 4, octandione-4, 5, nonandione-4, 5, 2-methylheptandione-4, 5, 2-methyloctandione-4, 5, and 2-methylnonandione-4, 5 in upto 78% yield. 相似文献
3.
El Sayed H. El Ashry Nagwa Rashed Ahmed Mousaad 《Journal of carbohydrate chemistry》2013,32(4):599-607
Abstract Dehydrative cyclization of the condensation product of 2, 3, 4, 5-tetra-O-acetyl-galactaryl chloride with anthranilic acid gave 1, 2, 3, 4-tetra-O-acetyl-1, 4-bis(4H-benzoxazin-4-one-2-yl)-galacto-tetritol. Its reaction with aniline in the presence of phosphorus trichloride afforded 1, 4-bis (3-phenylquinazolin-4-one-2-yl)-1, 2, 3, 4-tetra-O-acetyl-galacto-tetritol. 相似文献
4.
N. S. Mukhamedov É. L. Kristalovich Y. N. Plugar' K. Giyasov N. A. Aliev N. D. Abdullaev 《Chemistry of Heterocyclic Compounds》1994,30(8):982-984
In the acylation of benzoxazolin-2-ones by aromatic acid chlorides in the presence of 10-2 mole of ZnCl2, the yields of the corresponding 6-aroylbenzoxazolin-2-ones depend on the electronegativity of the acylating agent and the nucleophilicity of the benzoxazolin-2-ones.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1136–1138, August, 1994. 相似文献
5.
水溶剂中芳醛与5,5-二甲基-1,3-环己二酮的反应 总被引:6,自引:2,他引:6
芳醛1与5,5-二甲基-1,3-环己二酮(2)在氯化三乙基苄基铵(TEBA)催 化下在水中生成2,2'-芳业甲基双(3-羟基-5,5-二甲基-2-环己烯-1-酮 )(3),若在体系中有对甲苯磺酸存在时则生成3,3,6,6-四甲基-9-芳基- 1,8-二氧代八氢化氧杂蒽(4)或3,3-二甲基-9-(3-羟基-5,5-二甲基 -2-环己烯-1-酮-2-基)-1-氧代四氢代氧杂蒽(6)而不是生成3,产率接 近定量。 相似文献
6.
N. A. Poznanskaya S. N. Ivanova N. N. Mel'nikov N. I. Shvetsov-Shilovskii 《Chemistry of Heterocyclic Compounds》1969,5(6):719-720
N-(Aryloxycarbonyl)benzoxazolin-2-ones have been obtained from benzoxazolinones and aryl chloroformates and from N-(chlorocarbonyl) benzoxazolinones and phenols. These compounds possess acylating properties and with phenols in the presence of phenoxide ions they give diaryl carbonates. 相似文献
7.
The reaction of 2-chloroethyl isothiocyante with N-phenylethyleneimine in the presence of triethylamine gives 2-(2-chloroethyl)imino-3-phenyl-1,3-thiazolidine. A mixture (12) of 2-(2-chloroethyl)imino-3-phenyl-l,3-thiazolidine and 7-phenyl-2,3,5,6-tetrahydroimidazo-[2,1-b]thiazolinium chloride is obtained in the absence of a catalyst. The reaction of 2-chloroethyl isothiocyanate with ethylene sulfide in the presence of triethylamine gives 2,3,5,6-tetrahydrothiazolo[2,3-b]thiazolinium chloride, while the reaction with tetraethyl-ammonium bromide gives 2-ethyleneiminium-l,3-dithiolane chloride.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1651–1653, December, 1971. 相似文献
8.
9.
N. A. Poznanskaya S. N. Ivanova N. N. Mel'nikov N. I. Shvetsov-Shilovskii 《Chemistry of Heterocyclic Compounds》1972,5(6):719-720
N-(Aryloxycarbonyl)benzoxazolin-2-ones have been obtained from benzoxazolinones and aryl chloroformates and from N-(chlorocarbonyl) benzoxazolinones and phenols. These compounds possess acylating properties and with phenols in the presence of phenoxide ions they give diaryl carbonates. 相似文献
10.
N. P. Shusherina L. V. Betaneli G. B. Mndlyan A. U. Stepanyants 《Chemistry of Heterocyclic Compounds》1974,10(11):1329-1331
1-Alkyl-2-pyridones react with N-phenylmaleinimide and maleinimide stereoselectively via the scheme of the diene synthesis to give imides of 8-alkyl-8-azabicyclo[2.2.2]-4-octen-7-one-1,2-dioic acid. 3-Unsubstituted 2-pyridones form adducts with an endo configuration, whereas 1,3-dimethyl-2-pyridone gives an exo adduct under the same conditions. The endo- and exo-bridge adducts readily undergo retrograde diene disintegration on heating. 相似文献
11.
N. S. Ksenzhek L. I. Belen'kii Ya. L. Gol'dfarb 《Chemistry of Heterocyclic Compounds》1973,9(4):447-450
Acetylation of 2-methylmercaptothiophene by the action of acetyl chloride in methylene chloride at –70°C in the presence of excess AlCl3 gives a mixture of 5-methylmercapto-2-acetylthiophene, 5-methylmercapto-2,4-diacetylthiophene, and a small amount of 3-acetyl-substituted derivative. The acetylation of 2-methoxythiophene gives similar results. 5-Dimethylamino-2-acetylthiophene was obtained from 2-dimethylaminothiophene under similar conditions.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 486–489, April, 1973. 相似文献
12.
M. G. Lin'kova T. P. Vasil'eva V. M. Bystrova N. V. Kalyuzhnaya O. V. Kil'disheva I. L. Knunyants 《Russian Chemical Bulletin》1984,33(3):570-575
Conclusions A general method was developed for the preparation of previously unreported anhydrides of-sulfinocarboxylic acids, namely, 1,2-oxathiolan-5-one-2-oxides and 2,1-benzoxathibl-3-one-1-oxide (XIV) by the action of disodium salts of-oxysulfinylcarboxylic acids with oxalyl chloride.For Communication 9, see [1]Deceased.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 617–623, March, 1984. 相似文献
13.
Jean Guillaumel Pierre Demerseman Jean-Marc Clavel René Royer Nicole Platzer Christian Brevard 《Tetrahedron》1980,36(17):2459-2465
While β-nitrostyrene yields only hydroxymic or hydroxamic acid derivatives by treatment with acetyl chloride in the presence of zinc, tin, titanium or aluminium chloride, it also gives 3-chloro 2-indolinone and a 5-acetyl derivative of the latter, when the reaction is carried out with ferric chloride. The procedures of this reaction are examined, and a mechanism is suggested. 相似文献
14.
3-Methyl(amino)-1-phenylpyrazol-5-ones react with N-chlorosulfenylphthalimide to give 4-phthalimidothiopyrazoles which decompose to form 3-methyl(amino)-1-phenylpyrazol-5-one-4-thiones. They were identified as their spirocyclic adducts with dienes. Oxidation of the latter with m-chloroperbenzoic acid gives spirocyclic sulfoxides and sulfones.Institute of Organic Chemistry, Ukraine Academy of Sciences, Kiev 253660. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 187–192, February, 2000. 相似文献
15.
Various N-alkylsaccharins were easily prepared in moderate to good yields by the reaction of N-alkyl(o-methyl)arenesulfonamides with (diacetoxyiodo)benzene in the presence of iodine under irradiation with a tungsten lamp (W-hν). On the other hand, irradiation of N-alkyl(o- methyl)arenesulfonamide derivatives bearing various subslituents on the aromatic ring with a high- pressure mercury lamp (Hg-hν), in the presence of (diacetoxyiodo)benzene and iodine gave the corresponding N-alkyl-1,2-benzisothiazoline-3-one-1-oxide derivatives in moderate yields, together with N-alkyl-1,2-benzisothiazoline-3-one-1,1-dioxide (saccharin) derivatives. 相似文献
16.
Moist silver oxide oxidation of three isoquinuclidinic nitroxide ketones is described. 1,3,3-Trimethyl-2-azabicyclo[2.2.2]octane-5-one-2-oxyl 3, and 1,3,3,7-anti-tetramethyl-2-azabicyclo[2.2.2]octane-5-one-2-oxyl 4 lead to 6-aza-bicyclo[3.2.1]oct-3-ene-2-one-7-oxyl derivatives 6, 7, and 1,3,3,7-syn-tetramethyl-2-aza-bicyclo[2,2.2]octane-5-one-2-oxyl 5 to 8-substituted p-menthenones. 相似文献
17.
Oxidation of 2′-hydroxy-8-methylspiro[4H-benz-1,3-oxazin-2-one-6,1′-cyclopentane] or N-mesyl-2-(cyclopent-1-en-1-yl)-6-methylaniline provided the corresponding ketones. The rearrangement of these ketones oximes under treatment with thionyl chloride gave rise to nitriles of 5-(2-amino-3-methylphenyl)-5-oxopentanoic or 5-(2-methanesulfamido-3-methylphenyl)-5-hydroxypentanoic acids. By heating 5-(2-acetylamido-3-methylphenyl)-5-oxopentanoic acid with LiH in THF3-(2,8-dimethylquinol-4-on-3-yl)propanoic acid was obtained. 相似文献
18.
Sergey A. Yermolayev Nickolay Yu. Gorobets Oleg V. ShishkinSvetlana V. Shishkina Nicholas E. Leadbeater 《Tetrahedron》2011,67(16):2934-2941
The introduction of a hydrazine functionality into 2-(2-cyanovinyl)-3-oxo-cyclohex-1-ene enolates results in their spontaneous cyclizations with participation of the hydrazine moiety. Depending on the reaction conditions used, the hydrazine-derived enolates are transformed into derivatives of 1-arylpyridine-2-one-3-carbonitriles or pyrazoloquinolinones in a one-pot synthesis. They also react with anilines to give the corresponding N1-substituted pyridine-2-one-3-carboxamides. Product characterization was performed by means of spectroscopic and X-ray diffraction studies. In addition, for structure elucidation purposes, a counter synthesis of 1-arylaminopyridine-2-one-3-carboxamide was also carried out. 相似文献
19.
[reaction: see text] Oxidation of phthalahydrazide (1) with lead tetraacetate in the presence of furfural (3a) in methylene chloride gives [5,6]benza-3a,7a-diaza-3-carboxylindane-4,7-dione-1-ene (7a) in 64% yield. 5-Methylfurfural (3b) also reacted similarly to give the product 7b in 46% yield. Reaction of phathalazine-1,4-dione with thiophene-2-carboxaldehyde gives N-(2-formylthiophene)phthalahydrazide. 相似文献
20.
3-Substituted-2,2,5,5-tetramethylpyrrolidine nitroxides are stable free radicals used extensively in the synthesis of ‘spin labels’. The high resolution mass spectra of these nitroxides substituted with ? CH2OH, ? OH, ? NH2 and ?o have been recorded on magnetic tape and the elemental compositions of the ions calculated by computer. Ionisation by electron bombardment(70eV), gives rise to an even-electron molecular ion species. [M+1]+. ions are observed in the spectra of all compounds examined, except in the case of the 3-carbonyl compound, 2,2,5,5-tetramethylpyrrolid-3-one-1-oxyl. Loss of a methyl radical from these ions leads to the appearance of ions at [M -14]+. The predominant fragmentation for those compounds in which the substituents can supply electrons to the ring, is the sequential elimination of isobutene, nitric oxide and a hydrogen radical. In the case of the 3-hydroxy compound, these ions account for 23 percent of the total ion current. 2,2,5,5-Tetramethylpyrrolid-3-one-1-oxyl, which bears an electron-withdrawing substituent gives rise to a fragmentation pattern somewhat different from those of the other compounds. The main features are the absence of a peak at [M + 1]+˙ and the general phenomenon of fewer peaks but with higher intensities. 相似文献