Benzothiazines in synthesis. A total synthesis of pseudopteroxazole

An enantioselective total synthesis of the naturally occurring antitubercular agent pseudopteroxazole is described. The synthesis is organized around the use of a stereoselective, intramolecular addition of a sulfoximine carbanion to an alpha,beta-unsaturated ester to form an enantiomerically pure benzothiazine. Other important processes include a completely stereoselective intramolecular Friedel-Crafts alkylation and a stereoselective and regioselective hydrogenation. [structure: see text]     

Enynones in organic synthesis. III. A novel synthesis of phenols

Enynones are converted to phenols by an acid catalyzed process which can be controlled to give either of two regioisomeric series of products.     

A New polyamine synthesis.

A new flexible method for the step by step construction of polyamines based on the reaction of dichloroboranes with azides is reported.     

Thallium in organic synthesis. 63. A convenient synthesis of aromatic nitriles

Aromatic nitriles are readily formed by heating arylthallium bis(trifluoroacetates) with CuCN in acetonitrile.     

Aminohaloborane in organic synthesis. VI. A simple enantioselective aldol synthesis

A simple asymmetric aldol condensation of acetophenone and benzaldehydes was performed via chiral vinylaminodichloroborane. The enatioselectivity was compared with that by a similar method using magnesium and lithium.