X射线CT环形伪影去除方法

为去除X射线CT图像中的环形伪影,建立了一种投影数据预处理方法。该方法通过对各角度投影数据逐一进行分段多项式拟合的方式建立异常探元的备选校正因子集合,再根据备选校正因子的概率密度分布确定最可几校正因子。介绍了方法的物理依据、原理及其实现步骤,并分析了其在复杂条件下的适应性。结果表明:该方法对稀疏环形伪影、密集环形伪影以及伴随强噪声污染的CT图像环形伪影均可去除;与中值滤波等方法相比,可以更好地保持图像的空间分辨率。该方法可用于多材质检测对象CT图像的处理。     

利用荧光CT实现生物医学样品内元素分布的无损成像

荧光CT是一种可无损重建元素空间分布的发射型断层成像技术,对生物医学研究具有重要意义.同步辐射的高通量、高准直和能量可调等特性使荧光CT的生物医学应用成为可能.文章通过优化设计,在上海同步辐射光源建立了一套用于生物医学样品微量元素分析的荧光CT成像系统.通过对实验装置的优化,提高了系统的数据采集速度和空间分辨率.将极大...     

X‐ray fluorescence computed tomography with absorption correction for biomedical samples

To obtain accurate distributions of trace elements in biomedical samples nondestructively, the problems on absorption correction and radiation dose are confronted in X‐ray fluorescence computed tomography. In this paper, the absorption‐corrected ordered subsets expectation maximization (AC‐OSEM) algorithm is developed to solve these problems. Simulation results show that the AC‐OSEM‐based X‐ray fluorescence computed tomography is accurate when only the incident X‐ray attenuation map is known and relatively fewer projections are provided. In addition, for the biomedical samples, the simplified approximate expression of the fluorescence attenuation map is practicable. Experiments on the biomedical samples were also carried out to evaluate the applicability of the AC‐OSEM algorithm to soft tissues, which demonstrates that the distribution of the trace element Fe in the pathological liver could be clearly revealed. Copyright © 2014 John Wiley & Sons, Ltd.     

X-ray beam hardening correction for measuring density in linear accelerator industrial computed tomography

Due to X-ray attenuation being approximately proportional to material density,it is possible to measure the inner density through Industrial Computed Tomography（ICT） images accurately. In practice,however,a number of factors including the non-linear effects of beam hardening and diffuse scattered radiation complicate the quantitative measurement of density variations in materials. This paper is based on the linearization method of beam hardening correction,and uses polynomial fitting coecient which is obtained by the curvature of iron polychromatic beam data to fit other materials. Through theoretical deduction,the paper proves that the density measure error is less than 2% if using pre-filters to make the spectrum of linear accelerator range mainly 0.3 MeV to 3 MeV. Experiment had been set up at an ICT system with a 9 MeV electron linear accelerator. The result is satisfactory. This technique makes the beam hardening correction easy and simple,and it is valuable for measuring the ICT density and making use of the CT images to recognize materials.     

X-ray beam hardening correction for measuring density in linear accelerator industrial computed tomography

Due to X-ray attenuation being approximately proportional to material density, it is possible to measure the inner density through Industrial Computed Tomography (ICT) images accurately. In practice, however, a number of factors including the non-linear effects of beam hardening and diffuse scattered radia-tion complicate the quantitative measurement of density variations in materials. This paper is based on the linearization method of beam hardening correction, and uses polynomial fitting coefficient which is obtained by the curvature of iron polychromatic beam data to fit other materials. Through theoretical deduction, the paper proves that the density measure error is less than 2% if using pre-filters to make the spectrum of linear accelerator range mainly 0.3 MeV to 3 MeV. Experiment had been set up at an ICT system with a 9 MeV electron linear accelerator. The result is satisfactory. This technique makes the beam hardening correction easy and simple, and it is valuable for measuring the ICT density and making use of the CT images to recognize materials.     

Chemical effects on the L-shell X-ray fluorescence parameters of Ta and W compounds

The L shell X-ray production cross-sections, the intensity ratios_, and the average fluorescence yields of pure Ta, W and their compounds have been analysed. The targets were irradiated with γ-photons at 59.5 keV from a ²⁴¹Am annular source and detected using an Ultra-LEGe detector with resolution of 150 eV at 5.9 keV. The experimental results were compared with the other theoretical and experimental results. The obtained results were interpreted according to the chemical effect and influence of removing electrons from the shells above the L shell.     

Attenuation compensation for optical coherence tomography imaging

Optical coherence tomography (OCT) is a noninvasive technique that provides micrometer-scale imaging of tissue. As most biological tissues are considered turbid, it causes attenuation of the OCT signal and limits the depth penetration. Although a few algorithms had been developed to compensate the attenuation, almost all of them need to extract the scattering parameters before doing the compensation procedure. Because the real biological samples are anisotropic and multilayer-like structure, it is not time-efficient to model and solve these scattering parameters. This paper introduces a new method to compensate the OCT signal attenuation in depth. By analyzing the input signal, a compensation function is adaptively derived for each A-scan line, which can be used effectively to compensate the energy loss in the large sections and enhance the details in the deep, dark-like areas. Three bio-samples, a piece of onion, a Poecilia Wingei fish and a piece of rabbit abdominal aorta, were used to test our method. OCT images obtained by a swept-source OCT system were processed by the proposed method. Results show the visualization of structures in OCT images has been evidently improved, especially in deep region.     

CT计算机断层扫描成像实验

根据投影和断层成像原理,设计了CT计算机断层扫描成像原理性装置.使用该装置学生可以做硬件调试,软件编写、算法研究和系统测试等一系列实验,研究样品的投影成像和断层成像.本文从教学内容和教学方法上对CT计算机断层扫描成像实验进行了探讨.     

工业CT图像边缘伪影校正

为了去除工业CT图像中的边缘伪影,提高CT图像的识别能力和尺寸测量精度,提出一种降低串扰的系数修正法。首先分析得出边缘伪影主要是由散射射线在相邻探测通道之间的串扰所导致,并给出了探测通道串扰的数学模型;然后根据数学模型设计实验方案,通过对影响串扰率的主要因素进行实验分析,得到串扰率随入射X射线能量和被测物体厚度变化关系,再通过最小二乘拟合得出投影数据关于串扰率的函数;最后利用此函数对投影数据进行校正,降低了串扰的影响。实验结果表明,探测器间一级串扰率约为9.0%,二级串扰率约为1.2%,其中一级串扰是造成边缘伪影的主要因素,采用本文方法能够有效地抑制边缘伪影,同时较好地保留了图像细节和边缘。     

工业CT图像边缘伪影校正

为了去除工业CT图像中的边缘伪影,提高CT图像的识别能力和尺寸测量精度,提出一种降低串扰的系数修正法。首先分析得出边缘伪影主要是由散射射线在相邻探测通道之间的串扰所导致,并给出了探测通道串扰的数学模型;然后根据数学模型设计实验方案,通过对影响串扰率的主要因素进行实验分析,得到串扰率随入射X射线能量和被测物体厚度变化关系,再通过最小二乘拟合得出投影数据关于串扰率的函数;最后利用此函数对投影数据进行校正,降低了串扰的影响。实验结果表明,探测器间一级串扰率约为9.0%,二级串扰率约为1.2%,其中一级串扰是造成边缘伪影的主要因素,采用本文方法能够有效地抑制边缘伪影,同时较好地保留了图像细节和边缘。     

针对X射线双能CT成像的正弦图快速配准方法

双能CI成像技术在医学和安检领域应用广泛,可分为真双能成像和伪双能成像两种类型.针对真双能成像中存在的正弦图空间位置不匹配的问题,提出了一种高低能正弦图快速配准方法.该方法利用相关系数来检测高低能正弦图投影角度方向的相对位移.针对二维相关系数计算量大的问题,采用对正弦图横向左半部分或者右半部分进行横向投影的方法获取一维...     

X-ray spectra simulation of Li-like nickel L-shell Ions

The X-ray emission spectra of nickel plasma were simulated under the collisional radiative model (CRM) by using the flexible atomic code (FAC). The dynamical processes including collisional excitation (CE), radiative recombination (RR), dielectronic recombination (DR), collisional ionization (CI) and resonance excitation were considered in the model, and the rate coefficients of DR, RR as well as CI were consistent with previous results within 15%. It was found that the contributions to spectra from cascades and indirect processes could not be ignored. The intensities of spectral lines for lithium-like nickel L-shell ions are sensitive to the electron temperature. The good agreement between present spectral peaks and earlier observed results can be taken as a measure of the accuracy of the present work.     

衍射增强计算机断层技术研究

对衍射增强计算机断层技术进行了分析研究，提出了一种新方法.应用该方法只需在摇摆曲线一点处对物体进行360°范围内旋转投影成像，即可获得物体的折射率梯度分布以及吸收系数与散射系数和分布.该方法较以前的方法，大大简化了实验步骤. 关键词： 同步辐射 衍射增强 计算机断层     

Evaluation of dosimetry and image of very low-dose computed tomography attenuation correction for pediatric positron emission tomography/computed tomography: phantom study

In this study, phantom was used to evaluate attenuation correction computed tomography (CT) dose and image in case of pediatric positron emission tomography (PET)/CT scan. Three PET/CT scanners were used along with acryl phantom in the size for infant and ion-chamber dosimeter. The CT image acquisition conditions were changed from 10 to 20, 40, 80, 100 and 160 mA and from 80 to 100, 120 and 140 kVp, which aimed at evaluating penetrate dose and computed tomography dose index_volume (CTDI_vol) value. And NEMA PET Phantom? was used to obtain PET image under the same CT conditions in order to evaluate each attenuation-corrected PET image based on standard uptake value (SUV) value and signal-to-noise ratio (SNR). In general, the penetrate dose was reduced by around 92% under the minimum CT conditions (80 kVp and 10 mA) with the decrease in CTDI_vol value by around 88%, compared with the pediatric abdomen CT conditions (100 kVp and 100 mA). The PET image with its attenuation corrected according to each CT condition showed no change in SUV value and no influence on the SNR. In conclusion, if the minimum dose CT that is properly applied to body of pediatric patient is corrected for attenuation to ensure that the effective dose is reduced by around 90% or more compared with that for adult patient, this will be useful to reduce radiation exposure level.     

计算层析成像光谱技术研究进展

从技术特点和研究热点的角度,综述了近些年来计算层析成像光谱技术的国内外进展,主要包括计算层析成像光谱仪的系统结构改进及与其他技术联用的新集成设计,新器件新设备的研发和应用,仪器定标技术和目标重建算法的优化与改进等;并按照应用范围的特点进行了分类,对在探测波段扩展和应用领域拓展等方面的应用现状进行了总结.介绍了光栅型和旋转棱镜型计算层析成像光谱技术的原理,并展望了计算层析成像光谱技术的发展趋势.     

Noise reduction for low-dose X-ray computed tomography with fuzzy filter

Low-dose CT imaging has been particularly used in modern medical practice for its advantage on reducing the radiation dose to patients. However, reconstructed images will distinctly degenerate along with the decrease of the radiation dose. A resolution is to deal with the noisy projection space by an effective filter. This study was performed to address this problem and a fuzzy-median filter was proposed in this paper according to the properties of the noise of low-dose CT images. Reconstructed images by FBP were acquired from the previous noisy sinogram filtered by different filters for comparison. This fuzzy-median filter in fact is a spatially variant one that can solve the streak artifacts. And simulations also indicated that this spatially variant filter could suppress noise and obviously decrease streak artifacts in reconstructed images.     

Scatter correction for cone-beam computed tomography using self-adaptive scatter kernel superposition

The authors propose a combined scatter reduction and correction method to improve image quality in cone beam computed tomography (CBCT). The scatter kernel superposition (SKS) method has been used occasionally in previous studies. However, this method differs in that a scatter detecting blocker (SDB) was used between the X-ray source and the tested object to model the self-adaptive scatter kernel. This study first evaluates the scatter kernel parameters using the SDB, and then isolates the scatter distribution based on the SKS. The quality of image can be improved by removing the scatter distribution. The results show that the method can effectively reduce the scatter artifacts, and increase the image quality. Our approach increases the image contrast and reduces the magnitude of cupping. The accuracy of the SKS technique can be significantly improved in our method by using a self-adaptive scatter kernel. This method is computationally efficient, easy to implement, and provides scatter correction using a single scan acquisition.     

Region-of-interest tomography for grating-based X-ray differential phase-contrast imaging

We report numerical and experimental results demonstrating accurate region-of-interest computed tomography (CT) reconstruction based on differential phase-contrast projection (DPC) images. The approach removes the constraint of covering the entire sample within the field of view of the image detector. Particularly for biomedical applications, the presented DPC-CT region-of-interest approach will allow for the visualization of previously inaccessible details deep inside an entire animal or organ. We envisage that this development will also be of interest for potential future clinical applications, because grating-based DPC-CT can be implemented with standard x-ray tube sources.