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1.
3-Aroylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones reacted with 1,3,3-trimethyl-2-methylidene-2,3-dihydro-1H-indole (Fischer’s base) to give (2Z)-1-aryl-2-[3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene]-5-(1,3,3-trimethyl-2,3-dihydro-1H-indol-2-ylidene)pentane-1,3,4-triones. 相似文献
2.
Maksym S. Kazunin Oleksii Yu. Voskoboynik Inna S. Nosulenko Galina G. Berest Sergiy V. Kholodniak Boris O. Pryymenko Sergiy I. Kovalenko 《Journal of heterocyclic chemistry》2020,57(1):268-280
The synthesis of 6-(2-hydroxy-2-aryl (heteryl)ethyl)-1-methylpteridine-2,4,7(1H,3H,8H)-triones by the reduction of the corresponding ketones and the peculiarities of conversion of the synthesized alcohols to (E)-1-methyl-6-(2-aryl (heteryl)ethenyl)pteridine-2,4,7(1H,3H,8H)-triones was reported. The mechanism of monomolecular elimination that occurred in the presence of hydrogen halides was discussed, namely, the competitive formation of an energy-efficient conjugated system by deprotonation of a stable benzyl-type carbocation. Alternative synthesis methods of pteridine-2,4,7(1H,3H,8H)-triones were developed. Abovementioned approach involved [4+2]-cyclocondensation of 1-methyl-5,6-diaminouracil to 2-oxo-4-R-but-3-enoic acids and Knoevenagel condensation of 1,6-dimethylpteridine-2,4,7(1H,3H,8H)-trione with aromatic aldehydes. The antiradical, antimicrobial, and antifungal activities were studied for the synthesized compounds. 相似文献
3.
N. M. Tutynina N. L. Racheva V. A. Maslivets Z. G. Aliev A. N. Maslivets 《Russian Journal of Organic Chemistry》2013,49(1):95-98
3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with 5,5-dimethylcyclohexane-1,3-dione to give 3′-aroyl-4′-hydroxy-1′-(2-hydroxyphenyl)-6,6-dimethyl-6,7-dihydrospiro[1-benzofuran-3,2′-pyrrole]-2,4,5′(1′H,5H)-triones. The crystalline and molecular structures of 3′-benzoyl-4′-hydroxy-1′-(2-hydroxyphenyl)-6,6-dimethyl-6,7-dihydrospiro[1-benzofuran-3,2′-pyrrole]-2,4,5′(1′H,5H)-trione were determined by X-ray analysis. 相似文献
4.
Yu. N. Bannikova A. N. Maslivets Z. G. Aliev 《Russian Journal of Organic Chemistry》2007,43(9):1334-1337
Methyl 1-aryl-3-benzoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with 3-arylamino-5,5-dimethylcyclohex-2-en-1-ones in boiling benzene to give the corresponding 1,1′-diaryl-3′-benzoyl-4′-hydroxy-6,6-dimethyl-1,1′,2,4,5,5′,6,7-octahydrospiro[indole-3,2′-pyrrole]-2,4,5′-triones and 1′-aryl-4-arylamino-3-benzoyl-6′,6′-dimethyl-1′,2′,4′,5′,6′,7′-hexahydro-5H-spiro[furan-2,3′-indole]-2′,4′,5-triones whose structure was proved by X-ray analysis. 相似文献
5.
Tretyakov N. A. Shavrina T. V. Maslivets A. N. 《Russian Journal of Organic Chemistry》2019,55(5):719-720
Russian Journal of Organic Chemistry - 8-Aroyl-3,4-dihydropyrrolo[2,1-a][1,4]oxazine-1,6,7(1H)-triones were synthesized by the reactions of 3-(2-aryl-2-oxoethylidene)morpholin-2-ones with oxalyl... 相似文献
6.
A. N. Maslivets Z. G. Aliev O. P. Krasnykh O. V. Golovnina L. O. Atovmyan 《Chemistry of Heterocyclic Compounds》2004,40(10):1295-1299
3-Alkoxycarbonylmethylene-1-phenyl-1,2,3,4-tetrahydro-2-quinoxalones, obtained by the interaction of dialkyl esters of oxaloacetic acid and N-phenyl-o-phenylenediamine, react with oxalyl chloride with the formation of 3-alkoxycarbonyl-5-phenyl-1,2,4,5-tetrahydropyrrolo[1,2-a]quinoxaline-1,2,4-triones. Alkoxycarbonyl(2-oxo-1-phenyl-1,2-dihydro-3-quinoxalinyl)ketenes, generated on thermal decarbonylation of the latter, are stabilized by participation in a [4+2] cyclodimerization reaction with the formation of 2,4-di(alkoxycarbonyl)-2-(3-oxo-4-phenyl-3,4-dihydro-2-quinoxalinyl)-6-phenyl-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoxaline-1,3,5-triones. The crystal and molecular structure of the di(ethoxycarbonyl) derivative have been investigated by X-ray structural analysis.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1501–1506, October, 2004. 相似文献
7.
Russian Journal of Organic Chemistry - 8-Aroyl-3,4-dihydro-1H-pyrrolo[2,1-a][1,4]oxazine-1,6,7-triones reacted with 3-benzylamino-5,5-dimethylcyclohex-2-en-1-one to give... 相似文献
8.
Hitherto unknown [1] benzopyrano [3,4-c] [2] benzazepine-6,8,13(7H)-triones (4a-e) have been synthesized by the intramolecular cyclodehydration of N-(2-oxo-2H-1-benzopyran-3-yl) phthalamic acids (3a-e) obtained by the reaction of 3-amino coumarins (1a-e) with phthalic anhydride (2) 相似文献
9.
Methyl 3-aroyl-1-aryl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with 3-amino-5,5-dimethylcyclohex-2-en-1-one having no substituent on the nitrogen atom to give 3-aroyl-4-arylamino-6′,6′-dimethyl-6′,7′-dihydro-5H-spiro[furan-2,3′-indole]-2′,4′,5′(1′H,5′H)-triones or methyl 12-aroyl-11-aryl-9-hydroxy-5,5-dimethyl-3,10-dioxo-8,11-diazatricyclo[7.2.1.02,7]dodec-2(7)-ene-1-carboxylates. The latter underwent thermal recyclization to 3′-aroyl-1′-aryl-4′-hydroxy-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. 相似文献
10.
E. E. Stepanova A. V. Babenysheva A. N. Maslivets 《Russian Journal of Organic Chemistry》2011,47(6):937-940
[4 + 2]-Cycloaddition of 3-aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4(4H)-triones to alkyl vinyl ethers gave substituted stereoisomeric (1R*,16R*)- and (1S*,16R*)-16-alkoxy-14-aryl-3,15-dioxa-10-azatetracyclo[8.7.0.01, 13.04, 9]heptadeca-4,6,8,13-tetraene-2,11,12-triones. 相似文献
11.
N. L. Racheva S. N. Shurov Z. G. Aliev A. N. Maslivets 《Russian Journal of Organic Chemistry》2007,43(1):108-116
3-Aroyl-2,4-dihydro-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones react with N-unsubstituted and N-substituted 3-amino-5,5-dimethylcyclohex-2-en-1-ones to give 3′-aroyl-4′-hydroxy-1′-(o-hydroxy-phenyl)-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. The molecular and crystalline structure of the 1-cyclohexyl-substituted derivative was studied by X-ray analysis. 相似文献
12.
Maslivets A. N. Mashevskaya I. V. Kol'tsova S. V. Duvalov A. V. Feshin V. P. 《Russian Journal of Organic Chemistry》2002,38(5):738-743
The reaction of (Z)-3-phenacylidene-1,2,3,4-tetrahydroquinoxalin-2-ones with oxalyl chloride gives 3-aroyl-1,2,4,5-tetrahydropyrrolo[1,2-a]quinoxaline-1,2,4-triones which react with o-phenylenediamine to afford 8-aryl-6,7,9,14,15,16-hexahydroquinoxalino[1,2-a]pyrrolo[2,3-b][1,5]benzodiazepine-6,7,15-triones. 相似文献
13.
I. V. Mashevskaya Z. G. Aliev D. G. Mazhukin S. A. Popov A. Ya. Tikhonov A. N. Maslivets 《Russian Journal of Organic Chemistry》2008,44(8):1189-1193
3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with N,N′-dihydroxycyclohexane-1,2-diamine to give 3-aroyl-1′,4,4′-trihydroxy-1-(2-hydroxyphenyl)-4a′,5′,6′,7′,8′,8a′-hexahydro-1′H-spiro[pyrrole-2,2′-quinoxaline]-3′,5(1H,4′H)-diones which underwent rearrangement into 1′-aroyloxy-4,4′-dihydroxy-1-(2-hydroxyphenyl)-4a′,5′,6′,7′,8′,8a′-hexahydro-1′H-spiro[pyrrolidine-2,2′-quinoxaline]3′,4,5(4′H)-triones via [1,4]-migration of the aroyl group. The product structure was proved by X-ray analysis. 相似文献
14.
Erik G. Frandsen 《Tetrahedron》1978,34(14):2175-2178
A simple route to the hitherto unknown 1,3-bis-(1,2-dithiol-3-ylidene)-2-propanones is reported: 3-Methylthio-1,2-dithiolylium salts condense with 4-hydroxy-3H-pyran-2,6-dione to 3,5-bis-(1,dithol-3-ylidene)pyran-2,4,6-triones, which are converted by acidic hydrolysis into the propanones. 相似文献
15.
M. A. Mzhelskaya I. D. Ivanchikova N. E. Polyakov A. A. Moroz M. S. Shvartsberg 《Russian Chemical Bulletin》2004,53(12):2798-2804
Procedures were developed for the heterocyclization of 2-benzoylethynyl-1-hydroxy-and 1-hydroxy-2-(1-oxo-3-phenylpropynyl)anthraquinone. The regioselective preparation of 2-substituted anthra[1,2-b]pyran-4,7,12-triones was demonstrated to be possible under mild conditions.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2686–2692, December, 2004. 相似文献
16.
The reactions of 2,3,6,11-tetrahydroanthra[2,1-d]isothiazole-3,6,11-trione with dimethyl sulfate, benzyl chloride, and allyl bromide afforded the corresponding 2-alkyl-2,3,6,11-tetrahydroanthra[2,1-d]isothiazole-3,6,11-triones and 3-(alkoxy)-6,11-dihydroanthra[2,1-d]isothiazole-6,11-diones. The reactions of 2,3,6,11-tetrahydroanthra[2,1-d]isothiazole-3,6,11-trione and its S-oxide with a formaldehyde—secondary amine system yielded 2-[(alkylamino)methyl]-2,3,6,11-tetrahydroanthra[2,1-d]isothiazole-3,6,11-triones and 2-[(alkylamino)methyl]-3,6,11-trioxo-2,3,6,11-tetrahydroanthra[2,1-d]isothiazole 1-oxides, respectively. 相似文献
17.
V. V. Shchepin N. F. Kirillov M. I. Vakhrin O. B. Bayanova S. N. Shurov P. S. Silaichev 《Russian Journal of General Chemistry》2006,76(7):1146-1149
Reformatsky reagent generated from methyl 1-bromocyclohexane-1-carboxylate reacted with N-aryl-2-oxochromene-3-carboxamides and N-aryl-6-bromo-2-oxochromene-3-carboxamides to give, depending on the conditions, the corresponding N-aryl-(6-bromo)-4-(1-methoxycarbonylcyclohexyl)-2-oxochroman-3-carboxamides or 3-aryl-(9-bromo)-1,1-pentamethylene-2,3,4,4a,5,10b-hexahydro-1H-chromeno[3,4-c]pyridine-2,4,5-triones. The products were isolated as a single diastereoisomer. 相似文献
18.
3-Aroyl-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones react with 4-arylaminopent-3-en-2-ones and 3-amino-1,3-diphenylprop-2-en-1-ones to give substituted 4-aroyl-3-hydroxy-1-(o-hydroxyphenyl)-1,7-diazaspiro[4.4]nona-3,8-diene-2,6-diones. 相似文献
19.
20.
The highly reactive alkylaminofurochromenone intermediate, produced from the reaction between 3-formylchromones and alkyl isocyanides, was trapped by monocyclic unsaturated acyl compounds such as maleic anhydride or maleimide derivatives to yield new types of organic fluorophores 4-(alkylamino)-1H-furo[3,4-b]xanthene-1,3,10-triones or 4-(alkylamino)chromeno[2,3-f]isoindole-1,3,10(2H)-triones, which exhibited strong sky blue emission in solution. The reaction is very simple from an experimental point-of-view and allows the creation of a fused benzene ring with concomitant formation of three new C–C bonds in a single operation. 相似文献