Benzene‐1,4‐diboronic acid–4,4′‐bipyridine–water (1/2/2)

In the presence of water, benzene‐1,4‐diboronic acid (1,4‐bdba) and 4,4′‐bipyridine (4,4′‐bpy) form a cocrystal of composition (1,4‐bdba)(4,4′‐bpy)₂(H₂O)₂, in which the molecular components are organized in two, so far unknown, cyclophane‐type hydrogen‐bonding patterns. The asymmetric unit of the title compound, C₆H₈B₂O₄·2C₁₀H₈N₂·2H₂O, contains two 4,4′‐bpy, two water molecules and two halves of 1,4‐bdba molecules arranged around crystallographic inversion centers. The occurrence of O—H...O and O—H...N hydrogen bonds involving the water molecules and all O atoms of boronic acid gives rise to a two‐dimensional hydrogen‐bonded layer structure that develops parallel to the (01) plane. This supramolecular organization is reinforced by π–π interactions between symmetry‐related 4,4′‐bpy molecules.     

Magnesium iodide–4,4′‐bipyridine–water (1/3/4) and strontium iodide–4,4′‐bipyridine–propan‐1‐ol (1/2.5/2)

Both of the title compounds, catena‐poly­[[[tetra­aqua­magnesium(I)]‐μ‐4,4′‐bi­pyridine‐κ²N:N′] diiodide bis(4,4′‐bi­pyridine) solvate], {[Mg(C₁₀H₈N₂)(H₂O)₄]I₂·2C₁₀H₈N₂}_n, (I), and catena‐poly­[[[μ‐4,4′‐bi­pyridine‐bis­[di­iodo­bis­(propan‐1‐ol)­strontium(I)]]‐di‐μ‐4,4′‐bi­pyridine‐κ⁴N:N′] bis(4,4′‐bi­pyri­dine) solvate], {[Sr₂I₄(C₁₀H₈N₂)₃(C₃H₈O)₄]·2C₁₀H₈N₂}_n, (II), are one‐dimensional polymers which are single‐ and double‐stranded, respectively, the metal atoms being linked by the 4,4′‐bi­pyridine moieties. The Mg complex, (I), is [cis‐{(H₂O)₄Mg(N‐4,4′‐bi­pyridine‐N′)_(2/2)}]_(∞|∞)I₂·4,4′‐bi­pyridine and Mg has a six‐coordinate quasi‐octahedral coordination environment. The Sr complex, (II), is isomorphous with its previously defined Ba counterpart [Kepert, Waters & White (1996). Aust. J. Chem. 49 , 117–135], being [(propan‐1‐ol)₂I₂Sr(N‐4,4′‐bi­pyridine‐N′)_(3/2)]_(∞|∞)·4,4′‐bi­pyridine, with the I atoms trans‐axial in a seven‐coordinate pentagonal–bipyramidal Sr environment.     

Leurosine me­thio­dide–methanol–water (1/3/2)

The crystal structure of a methanol–water solvate ofleurosine me­thio­dide, (leurosine‐CH₃)⁺I^?·3CH₃OH·2H₂O (C₄₇H₅₉IN₄O₉·3CH₃OH·2H₂O), is described. The piperidine ring of the upper part of the mol­ecule adopts a sofa conformation. An intramolecular hydrogen bond between the tertiary N and the hydroxyl group of the vindoline moiety of the mol­ecule is present.     

Felodipine–diazabicyclo[2.2.2]octane–water (1/1/1)

The title compound, C₁₈H₁₉Cl₂NO₄·C₆H₁₂N₂·H₂O, is a cocrystal hydrate containing the active pharmaceutical ingredient felodipine and diazabicyclo[2.2.2]octane (DABCO). The DABCO and water molecules are linked through O—H...N hydrogen bonds into chains around 2₁ screw axes, while the felodipine molecules form N—H...O hydrogen bonds to the water molecules. The felodipine molecules adopt centrosymmetric back‐to‐back arrangements that are similar to those present in all of its four reported polymorphs. The dichlorophenyl rings also form π‐stacking interactions. The inclusion of water molecules in the cocrystal, rather than formation of N—H...N hydrogen bonds between felodipine and DABCO, may be associated with steric hindrance that would arise between DABCO and the methyl groups of felodipine if they were directly involved in hydrogen bonding.     

Isoamyl­cobalamin–acetone–water (1/0.385/12.650)

The title compound, [Co(C₅H₁₁)(C₆₂H₈₈N₁₃O₁₄P)]·0.385C₃H₆O·12.650H₂O, contains the isoamyl (3‐methyl­butyl) anion bonded to the Co^III ion through a C atom. The compound is thus a structural analog of the two biologically important vitamin B₁₂ coenzymes adenosyl­cobalamin and methyl­cobalamin. The lower axial Co—N bond length [2.277 (2) Å] is one of the longest ever reported for a cobalamin and reflects the strong σ‐donor ability of the isoamyl group.     

Hexa­methyl­enetetra­mine–4‐nitro­catechol–water (1/2/1)

In the title adduct, 1,3,5,7‐tetra­aza­tri­cyclo[3.3.1.1^3,7]dec­ane–4‐nitro­benzene‐1,2‐diol–water (1/2/1), C₆H₁₂N₄·2C₆H₅NO₄·H₂O, the hexa­methyl­ene­tetra­mine mol­ecule acts as an acceptor of intermolecular O—H?N hydrogen‐bonding interactions from the water mol­ecule and the hydroxy groups of one of the two symmetry‐independent 4‐nitro­catechol mol­ecules. The structure is built from molecular layers which are stabilized by three intermolecular O—H?O, two intermolecular O—H?N and four intermolecular C—H?O hydrogen bonds. The layers are further interconnected by one additional intermolecular O—H?N and two intermolecular C—H?O hydrogen bonds.