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A new “branch” for polyketide synthases was discovered in the biosynthesis of the antimitotic rhizoxin complex in the endofungal bacterium Burkholderia rhizoxinica. Genetic engineering and the structural elucidation of pathway intermediates revealed that a complex polyketide chain is branched at the β position by an unprecedented conjugate addition of an acetyl building block to an acryloyl precursor (see scheme).

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Programmable organic light‐emitting diodes: UV irradiation converts an oxetane‐functionalized dithienylethene derivative from its colorless open form into a dark blue closed form, while visible light reverses the reaction. In the Communication on page 4038 ff., K. Meerholz and co‐workers describe a reversibly switchable organic light‐emitting diode based on this principle.

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