Reacting in the 'Ni'ck of time : The title reaction is realized by using an isolated NiII complex ( 1 ). The catalysis tolerates a wide range of important functional groups that are often incompatible with Grignard reagents in cross‐coupling reactions.
The synthesis of partly fluorinated 1,3‐ and 1,4‐dienes by palladium‐catalyzed coupling makes these compounds available on the laboratory scale. Several catalyst systems were tested to maximize the yields and minimize the by‐products. The molecular structures of 1,1,2,4,4‐pentafluorobutadiene, chloro(N,N′‐tetramethylethylenediamine)(trifluorovinyl)zinc, PCy2R, and P(O)Cy2R (Cy=cyclohexyl, R=2‐(1‐naphthyl)phenyl) were elucidated by X‐ray crystallography. 相似文献
Palladium can tailor fullerenes : Palladium catalysts enable a number of C? H bond transformations of organo(hydro)fullerene. In addition to anticipated coupling reactions (C? H bond allylation and arylation), an unexpected new C? H bond dimerization reaction and C? C bond‐cleavage reaction were also uncovered.
Transition‐metal‐catalyzed alkenylation of enolates provides a direct method to synthesize broadly useful β,γ‐unsaturated carbonyl compounds from the corresponding carbonyl compound and alkenyl halides. Despite being reported in the early seventies, this reaction class saw little development for many years. In the past decade, however, efforts to develop this reaction further have increased considerably, and many research groups have reported efficient coupling protocols, including enantioselective versions. These reactions most commonly employ palladium catalysts, but there are also some important reports using nickel. There are many examples of this powerful transformation being used in the synthesis of complex natural products. 相似文献
