Analytical Chemistry — today''s definition and interpretation

Conclusions Today Analytical Chemistry requires a broader definition than that concerned with its classical concept, objectives and methodology. The new concept of sample as a condensation of information of analytical interest has to be considered, as well as the increasing amount of instrumentation and metrology (physics) and data processing (applied mathematics; chemometrics) which are part of the present holistic definition of the subject. This is because the actual goals and constantly growing new objectives which today's Analytical Chemistry has to face and accomplish, are bound to a preliminary, strategic overview of the analytical problem (which often means much more than a simple sample). This problem has to be solved by the sensible, tactical application of the most suitable analytical method(s), worked out by Analytical Chemistry, the mother science of its instrument, chemical analysis.     

Analytical Chemistry — today''s definition and interpretation

Conclusion The definition of Analytical Chemistry given above reflects not only the place, importance, structure and functions of this science today but also the trends in its evolution. Its nearest perspective are the rise of analytical knowledge to the higher levels in the hierarchy of the system of chemistry, the creation of new analytical methods for study of the composition, structure and dynamics of ever more highly organized chemical objects up to living reactors.     

Analytical Chemistry — today''s definition and interpretation

Conclusion Although this multidisciplinary branch of science is growing rapidly today, yet two main points remain unchanged. On the one hand, it is analytical in essence; on the other, the information which it aims to acquire is chemical in nature, i.e. within the domain of chemistry. Accordingly it seems pertinent to reserve the term Analytical Chemistry for it. Other terms like analytical physics and chemical characterization are one-sided, with the aim or essence missing. The same is true of analytics and analytical science. Moreover, they should, literally speaking, include analytic geometry, analytical mechanics and so on.     

Analytical Chemistry — a time for change?

A report of the RSC-Analytical Division Automated Methods Group Symposium, held in Ferndown, Dorset, U.K., 28–30 October 1987.     

Ion Mobility Sensor In Environmental Analytical Chemistry—Concept And First Results

Abstract

Ion mobility spectrometry is a technique for generating ions at atmospheric pressure via ion-molecule reactions, and for analysing them in an ion drift tube.

The time required for the ions to traverse the length of the drift tube is mainly a function of the mass and the charge of the ions. Besides, ion shape and polarizability also affect the drift time.

Ion mobility spectrometry does not allow structural identification and quantification of unknown substances in mixtures. However, under certain boundary conditions it provides selective fingerprints of the substances to be observed, and operates at the ppbv concentration level and the millisecond time scale.

Through further miniaturization of a recently developed instrument of this type an ion mobility sensor is to be constructed. This sensor includes drift channel, operating shutter, collecting electrode, electronic data acquisition and translation board. The sensor makes possible to obtain real-time ion mobility spectra.

We present and discuss the concept of a small ion mobility spectrometer, its operation principle and first results on the way towards its further miniaturization.     

NEWS——基于等离子共振的分析信号放大

构建具有灵敏度高、选择性好、范围宽等优异特性的生物传感器是分析化领域的永恒目标.同济大学化学系田阳研究小组报道了基于金/针状二氧化钛纳米(Au/TiO2)复合膜的细胞色素c(Cyt.c)直接电子传递,同时通过Au NPs的等离子共振诱导其氧化还原电流的增大,从面提高了检测H2O2的分析特性,构建了新型H2O2光电化学传感器(Anal.chem.,Article SASP.DOI:10/1021/ac900894p).     

一个形象、生动的化学实验模拟软件——Crocodile Chemistry简介

Crocodile Chemistry是一个化学类实验模拟软件,它提供了100多种化学药品和实验仪器,可以生动地模拟无机、分析、物化等实验,其界面简洁友好,操作简单方便,图形及动画直观生动。使用Crocodile Chemistry不仅可以定性显示化学反应现象,还可以利用其提供的图表工具从定量的角度描述化学反应。本文主要介绍了Crocodile Chemistry的操作界面、主要内容和功能特点,并附案例说明具体的操作方法。     

NEWS——磁场固定毛细管电色谱柱的制备及评价、半胱氨酸在有序介孔碳修饰电极上的电化学行为及检测

毛细管电色谱(CEC)集毛细管电泳的高柱效和高效液相色谱的高选择性为一体,在药物和生物分析领域有着巨大的应用潜力.最近,天津大学药物科学与技术学院的万谦宏研究组在Anal.Chem.,2007,79(13)：5082～5086发表的论文中,报道了制备毛细管电色谱柱的新方法.     

NEWS——基于CdS纳米晶的电致化学发光生物传感器

南京大学化学化工学院朱俊杰研究组最近研制了一种基于CdS纳米晶的电致化学发光(ECL)生物传感器(Analytical Chemistry,2007,79,5574—5581)。通过自组装与金纳米颗粒放大技术研制成一种新型的纳米晶体非标记型电化学发光生物传感器,并将其运用于LDL的检测。该传感器具有重     

简介一本优秀的普通化学教材——Chemistry

RaymondChang编写的Chemistry（2010年已出版了第10版,基本3年左右更新一版）是一本侧重化学原理、理论与应用相结合的普通化学教科书。Chang在编写中刻意利用日常生活中的例子说明编写基本原则,培养学生解决问题的能力和思维方式。     

NEWS——高灵敏检测腺苷的可再生电化学传感系统、绿色高效的三联吡啶钌电化学发光体系

湖南大学化学化工学院沈国励研究组研制出一种高灵敏检测腺苷的可再生电化学传感系统(Analytieal Chemistry,2007,79(7):2933-2939)。该传感系统具有如下优势:酪胺电聚合膜提供良好的再生性和稳定性;纳米金层提供相对大的比表面积;电活性物质二茂铁的实用性;目标物的识别反应引起检测探针脱落而有效削弱了残余峰电流。     

NEWS——基于CdS纳米晶的电致化学发光生物传感器（Ⅰ）

南京大学化学化工学院朱俊杰研究组最近研制了一种基于CdS纳米晶的电致化学发光（ECL）生物传感器（Analytical Chemistry,2007,79,5574-5581）。通过自组装与金纳米颗粒放大技术研制成一种新型的纳米晶体非标记型电化学发光生物传感器,并将其运用于LDL的检测。该传感器具有重现性好,响应速度快,稳定性好等优点。半导体纳米晶通过电化学反应产生氧化态或还原态,     

NEWS——新型大气压直流辉光放电电离源及其在离子迁移谱中的应用（Ⅰ）

近年来,离子迁移谱（ion mobility spectrometry,IMS）被广泛地应用于爆炸物、毒品、化学战剂以及环境与大气污染物的实时在线监测。它具有分析速度快、灵敏度高、能量损耗低、易实现便携等突出优点。离子源是离子迁移谱仪的关键部件之一。     

NEWS——基于色谱-质谱的潜在标志物分子结构鉴定系统方案（I）

在疾病研究中发现新的特异性生物标志物是当前研究的热点和难点。疾病标志物研究的方向正在由单一标志物向多标志物模式转变。代谢组学通过考察生物体系受刺激或基因改变后其代谢产物的变化来发现一系列潜在生物标志物,从而研究生物体系的代谢途径。潜在生物标志物主要通过多变量统计分析方法对样本的LC-MS指纹图谱进行分析得到。     

虚拟现实技术在化学分子结构教学上的应用简介

利用开源免费的软件VESTA,Jmol以及Blender制作金刚石晶体结构和氨气分子空间结构的VR3D动画,通过简单的、交互式的网页设计和VR眼镜来体验虚拟现实技术所提供的沉浸式的体验感来激发学生的学习兴趣,为化学分子结构教学提供参考。     

NEWS—高质量宽频检测的实用改进型电化学衰减全反射表面增强红外光谱

表面增强红外光谱（surface—enhanced IR absorption spectroscopy,SEIRAS）是一种研究电极界面分子结构信息的重要分析工具。配以衰减全反射（attenuated total reflection,ATR）模式的表面增强红外吸收光谱（ATR—SEIRAS）具有表面信号强、表面选律简单,可避免传统外反射红外吸收光谱（IRAbsorption Spectroscopy,IRAS）面临的问题,