共查询到20条相似文献,搜索用时 15 毫秒
1.
Xiongming Luo Shuhua Qi Hao Yin Zhihui Xiao Si Zhang 《Magnetic resonance in chemistry : MRC》2009,47(12):1110-1114
Four new coumarins, micromelosides A–D, together with four known coumarins were isolated from the stem bark of Micromelum falcatum. The complete assignments of the 1H and 13C NMR chemical shifts for these new compounds were achieved by means of 1D and 2D NMR techniques, including 1H‐1H COSY, HSQC, HMBC and NOE difference. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
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Yaming Zhou Abdessamad Debbab Victor Wray WenHan Lin Barbara Schulz Rozenn Trepos Claire Pile Claire Hellio Peter Proksch Amal H. Aly 《Tetrahedron letters》2014
Chromatographic separation of a crude extract obtained from the fungus Aspergillus sp., isolated from the Mediterranean sponge Tethya aurantium, yielded a new tryptophan derived alkaloid, 3-((1-hydroxy-3-(2-methylbut-3-en-2-yl)-2-oxoindolin-3-yl)methyl)-1-methyl-3,4-dihydrobenzo[e][1,4]diazepine-2,5-dione (1), and a new meroterpenoid, austalide R (2), together with three known compounds (3–5). The structures of the new compounds were unambiguously elucidated on the basis of extensive one and two-dimensional NMR (1H, 13C, COSY, HMBC, and ROESY) and mass spectral analysis. Interestingly, the compounds exhibited antibacterial activity when tested against a panel of marine bacteria, with 1 selectively inhibiting Vibrio species and 2 showing a broad spectrum of activity. In contrast, no significant activity was observed against terrestrial bacterial strains and the murine cancer cell line L5178Y. 相似文献
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Kongkiat Trisuwan Vatcharin Rukachaisirikul Kawitsara Borwornwiriyapan Souwalak Phongpaichit Jariya Sakayaroj 《Tetrahedron letters》2014
Two new benzopyranones, named coniochaetones E (1) and F (2), one new xanthone, penicillone C (3), and one new benzophenone, penicillanone (4), are isolated from the soil fungus Penicillium citrinum PSU-RSPG95, together with ten known compounds. Their structures are identified on the basis of spectroscopic data. The isolated compounds are evaluated for their cytotoxic activity. 相似文献
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Ly Dieu Ha Poul Erik Hansen Fritz Duus Hung Dinh Pham Lien‐Hoa D. Nguyen 《Magnetic resonance in chemistry : MRC》2012,50(3):242-245
Four new prenylated depsidones, oliveridepsidones A–D, were isolated from the bark of Garcinia oliveri collected in Vietnam. Their structures were elucidated using mainly NMR techniques (1H and 13C NMR, HMQC, HMBC and NOE experiments). Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
8.
I. I. Dovgii V. I. Grishkovets V. V. Kachala A. S. Shashkov 《Chemistry of Natural Compounds》2005,41(2):200-204
The 3-O-β-D-glucopyranoside of β-sitosterol (1) and the known triterpene glycosides 3-O-α-L-arabinopyranosides of oleanolic (2a) and ursolic (2b) acids and hederagenin (3), 3-O-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosideofoleanolic acid (4), 3-O-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosides of oleanolic (5a) and ursolic (5b) acids and the newglycoside 28-O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranoside of 23-hydroxyursolic acid (6) were isolated from leaves of Cussonia paniculata (Araliaceae). Their structures were established using chemical methods and NMR spectroscopy.__________Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 160–163, March–April, 2005. 相似文献
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Hong Mei Li Wei Guang Wang Xiao Nian Li Yong Zhao Rong Tao Li Han Dong Sun 《中国化学快报》2008,19(12):1450-1452
A new cinnamic acid monoterpenoid ester, intermedin C (1), was isolated from the aerial parts of Schisandra propinqua var. interthedia. The structure of 1 was elucidated by spectroscopic methods including extensive ^1D and 2D NMR techniques. 相似文献
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Dang Ngoc Quang Marc Stadler Jacques Fournier Toshihiro Hashimoto 《Tetrahedron》2006,62(26):6349-6354
Four azaphilones named cohaerins C-F, along with 4,5,4′,5′-tetrahydroxy-1,1′-binaphthyl were isolated from the methanolic extract of the stromata of Annulohypoxylon cohaerens (Ascomycetes, Xylariaceae). Cohaerins C-E constitute typical azaphilones, bearing a γ-lactone ring, while cohaerin F has an unprecedented carbon skeleton, lacking the lactone ring of the azaphilones and with an aliphatic side chain being attached directly to the azaphilone backbone by a C-C bond. Their structures were determined by 2D NMR, IR, UV, and CD spectroscopy. They showed moderate inhibitory activity of nitric oxide production in RAW cells, and strong and nonselective antimicrobial effects. 相似文献
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Li-Mei Li Guo-You Li Li-Sheng Ding Chun Lei Li-Bin Yang Yong Zhao Zhi-Ying Weng Sheng-Hong Li Sheng-Xiong Huang Wei-Lie Xiao Quan-Bin Han Han-Dong Sun 《Tetrahedron letters》2007,48(52):9100-9103
Three new 6,7-seco-ent-kauranoids (1–3) were isolated and structures were elucidated from Isodon sculponeatus. Diterpenoids 1–3 possessing multicyclic skeletons formed via oxygen atoms are all unprecedented among ent-kauranes. Compound 1 displayed significant cytotoxic activity against K562, A549, and HepG2 human tumor cell lines, with IC50 values of 1.4, 2.3, and 2.0 μM, respectively, equal to the positive control. Plausible pathways for the biosynthesis of 1 and 2 from one related diterpenoid were also postulated. 相似文献
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Bacillamide, a novel algicide from the marine bacterium, Bacillus sp. SY-1, against the harmful dinoflagellate, Cochlodinium polykrikoides 总被引:1,自引:0,他引:1
Seong-Yun JeongKeishi Ishida Yusai ItoShigeru Okada Masahiro Murakami 《Tetrahedron letters》2003,44(43):8005-8007
Bacillamide (1) was isolated as a new algicide against the harmful dinoflagellate, Cochlodinium polykrikoides, from the marine bacterium, Bacillus sp. SY-1, and its structure was elucidated by extensive two-dimensional NMR techniques including 1H-15N HMBC analysis and mass analysis. Bacillamide showed algicidal activity against C. polykrikoides with LC50 of 3.2 μg/ml. 相似文献
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Six eremophilane sesquiterpenes were obtained from a marine fungus Penicillium sp. BL27-2. Their structures were elucidated as 3-acetyl-9, 7 (11)-dien-7a-hydroxy-8-oxoeremophilane (1), 3-acetyl-13-deoxyphomenone (2), Sporogen-AO 1 (3), 7-hydro- xypetasol (4), 8a-hydroxy-13-deo -xyphomenone (5) and 6-dehydropetasol (6) based on detailed NMR analysis. 1 was a new compound and 2 was obtained as a new natural compound. These compounds were assayed for their cytotoxic activity on P388, A549, HL60, BEL7402 and K562 cell lines by the MTT method. The assay results suggested the epoxide rings in eremophilane molecules were essential for their activity, and acetylation could enhance their activity. 相似文献
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Masato IwatsukiToshiya Ishimori Tsuyoshi YamamotoKeiko Takata Mihoko Mori Kenichi NonakaRokuro Masuma Yoichi HayakawaHideaki Hanaki Kazuro Shiomi Satoshi ōmura 《Tetrahedron》2011,67(35):6644-6648
Biverlactones, new circumventors of arbekacin resistance in methicillin-resistant Staphylococcus aureus (MRSA) were isolated from a culture broth of Penicillium sp. FKI-4429. Their structures were elucidated by spectroscopic studies, including various NMR experiments. Biverlactones A-D had novel skeletons, consisting of a lactone ring conjugated with exo- or endo-olefin, a carboxylic group and a characteristic alkyl side chain in common. 相似文献
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Ernesto FattorussoPaolo Luciano Masteria Yunovilsa Putra Orazio Taglialatela-Scafati Angela IanaroElisabetta Panza Giorgio BavestrelloCarlo Cerrano 《Tetrahedron》2011,67(41):7983-7988
Chemical analysis of the Indonesian soft coral Sinularia sp. (order Alcyonacea, family Alcyoniidae) afforded two known and three new C-4 norcembranoids, named chloroscabrolides A (3) and B (4) and prescabrolide (5). Chloroscabrolide A is a pentacyclic norcembranoid including an unprecedented THF-type ring to connect C-13 and C-15; furthermore, it is only the second chlorinated cembranoid derivative to be reported in the literature. The relative configuration of chloroscabrolide A has been established on the basis of a comparison between experimental 13C NMR data and DFT-calculated 13C NMR chemical shifts. All the isolated norcembranoids have been evaluated for iNOS protein inhibition. 相似文献
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From the branch tissue of Cephalotaxus mannii, the endophytic fungal strain CMM was isolated and determined to belong to the genus Aspergillus according to its internal
transcribed spacer (ITS) sequence of rDNA (ITS1-5.8S-ITS2). From the extracts of the fermentation broth of CMM, a new compound,
namely 5-O-α-D-glucopyranosyl-5-hydroxymellein (1), was isolated, together with a known compound 4-hydroxymellein (2). Their structures were elucidated on the basis of 1D and 2D NMR data.
Published in Khimiya Prirodnykh Soedinenii, No. 5, pp. 461–462, September-October, 2008. 相似文献
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Masahiko Isaka Somporn Palasarn Patchanee Auncharoen Somjit Komwijit E.B. Gareth Jones 《Tetrahedron letters》2009,50(3):284-287
Acremoxanthones A and B, novel anthraquinone-xanthone heterodimers with a unique linkage pattern, together with two known compounds, acremonidins A and C, were isolated from the fungus Acremonium sp. BCC 31806. The structures of the acremoxanthones were determined by analysis of 2D NMR and mass spectrometric data. Acremoxanthones and acremonidins exhibited antibacterial, antifungal, antiplasmodial, and cytotoxic activities. 相似文献
19.
Four new cembranolide diterpenes, sarcophytonolides A–D ( 1 – 4 ), were isolated from a Hainan soft coral Sarcophyton sp. Their structures were elucidated on the basis of detailed spectroscopic analysis and by comparison with related model compounds. 相似文献
20.
Masahiko Isaka Rachada HaritakunSumalee Supothina Wilunda ChoowongSuchada Mongkolsamrit 《Tetrahedron》2014
Six new compounds, an N-hydroxypyridone glucoside, orbiocrellin A (1), its aglycone orbiocrellin B (2), chromone glucosides 3 and 4, a dihydrochromone 5a/5b, and a chromone 6, were isolated from the scale-insect pathogenic fungus Orbiocrella sp. BCC 33248. Orbiocrellin A (1) exhibited antimalarial activity against Plasmodium falciparum K1 (IC50 3.1 μg/mL) while it was non-cytotoxic. In contrast, orbiocrellin B (2) showed both antimalarial (IC50 2.1 μg/mL) and cytotoxic (NCI-H187 cells, IC50 0.70 μg/mL) activities. 相似文献