Reactions of aldehydes of the furan series. 3. Oxidative-reductive conversions on the surface of alkali granules

Furan aldehydes undergo an oxidative-reductive disproportionation over solid alkali in a solvent inert to alkali. Molecular oxygen increases the yield of the furan carboxylic acid. A reaction scheme is proposed that takes into account the important role of alcoholates of gem-polyols.For Communication 2, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 741–744, June, 1990.     

Molecular orbital studies on the structure of nucleoside analogs. IV. Conformation of 3-deazapurine nucleosides

Conformational properties of 3-deazapurine nucleosides (namely, 3-deazaadenosine and 3-deazaguanosine) have been investigated by the PCILO method. Both C(2′)-endo and C(3′)-endo sugar puckers have been considered and the results indicate that the conformational preferences of these nucleoside analogs are quite different from those of their parent nucleosides adenosine and guanosine, respectively. This result has been correlated in terms of the biological inactivity of these nucleoside analogs.     

Synthesis and conversions of sulfides in thiophene series

Conclusions In the action of 4 equiv of sodium in liquid ammonia on methyl 2-ethylmereapto-5-ethyl-3-thiophene-carboxylate the principal reaction product is the amide of 2-mercapto-5-ethyl-3-thiophenecarboxylic acid (III).Translated from Izvetiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 10, pp. 2260–2265, October, 1969.