Synthese D'aminodiacides

A general method for the synthesis of a new aminodiacids ($\text{4}$) by aminodiesters ($\text{3}$)hydrolysis is presented.     

Synthese funktioneller Carbonsäure-Silylester

Synthesis of Functional Carboxylic Acid Silylester Di-tert-butylsilandiol reacts with organic acid chlorides to chlorosilanoles R₂Si(OH)Cl 1 (R = t-Bu). The phosphoric acid silylester 2 is obtained from 1 and POCl₃. Lithiated halogenosilanoles react with carboxylic acid chlorides to give silylesters ( 3 – 7 ). Lithium (trimethyl-acetoxy)silanolate 8 is obtained in the reaction of the lithiated diol with the chloride of trimethylacetic acid. The analogous reaction with benzoyl chloride lead to the formation of the bis(benzoic acid) silylester 9 . The condensation product 10 is obtained in the reaktion of the lithiated aminosilanol (t-Bu)₂Si(NH₂)OLi with trimethylacetic acid chlorid and condensation of the formed ester with aminosilanol.     

Synthese d'ethyleniques monofluores

Monofluorinated ethylenic compounds have been prepared by action of potassium tertiobutylate either on2-fluorotosylates or 2-fluorochlorides. In the case of 2-fluorochlorides the action, at higher temperature, of basic salt such as KF in ethylene glycol, may be used to prepare monofluorinated ethylenics compounds.