Reformatsky Reaction of Methyl 1-Bromocyclohexanecarboxylate with N,N′-(1,4-Phenylene)bis(1-arylmethanimines)

Russian Journal of Organic Chemistry - Reformatsky reagent prepared from methyl 1-bromocyclohexanecarboxylate reacted with N,N′-(1,4-phenylene)bis(1-arylmethanimines) to produce...     

Interaction of 1,1′-(hexane-1,6-diyl)bis[3-(4,4-diethoxybutyl)urea] with resorcinol derivatives. Synthesis of bisarylpyrrolidines

Russian Journal of General Chemistry -     

Synthesis,Spectral Characterization,and Antimicrobial Evaluation of N,N′-(1,4-Phenylene)diurea Derivatives

Russian Journal of Organic Chemistry - A series of new 1,1′-(1,4-phenylene)diurea derivatives were synthesized by reacting 1,4-diiso­cyanato­benzene with various biologically...     

Coordination compounds of copper and nickel with N,N′-[4,4′-(perfluoro-1,4-phenylene)bis(oxy)bis(4,1-phenylene)]-bis[2-(pyridin-2-ylmethylidene)hydrazinecarbothioamide] and its derivatives

N,N′-[4,4′-(Perfluoro-1,4-phenylene)bis(oxy)bis(4,1-phenylene)]bis[2-(pyridin-2-ylmethylidene)-hydrazinecarbothioamide] as well as its methyl and phenyl derivatives react with copper and nickel chlorides in ethanol to form coordination compounds. In the products, the hydrazinecarbothioamides act as doubly deprotonated bridging ligands. The prepared complexes have been found to inhibit in vitro the growth and propagation of the myeloid human leukemia HL-60 cancer cells at the 10^?5–10^?7 mol/L concentration.     

Synthesis of N,N′-Bis(arylsulfanyl)cyclohexa-2,5-diene-1,4-diimines and N,N′-(Cyclohexa-2,5-diene-1,4-diylidene)bis(arenesulfinamides)

Russian Journal of Organic Chemistry - Reactions of (chlorosulfanyl)benzenes with benzene-1,4-diamines afforded new N,N′-bis(arylsul­fanyl)cyclohexa-2,5-diene-1,4-diimines which were...     

Synthesis and structure of N,N′-bis(dihexylphosphorylmethyl)-1,4-diaminobutane

Russian Journal of General Chemistry - N,N′-Bis(dihexylphosphorylmethyl)-1,4-diaminobutane has been obtained via the Kabachnik–Fields reaction. Crystal structure of its salt with nitric...     

Reaction of Pyrrolobenzoxazinetriones with N,N′-Disubstituted Ureas. Synthesis of Substituted Spiro[imidazole-2,2′-pyrroles]

Russian Journal of Organic Chemistry - 3-Aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with symmetrical N,N′-disubstituted ureas to give 1,3-disubstituted...     

Synthesis of Spiro[1,4-benzothiazine-2,2′-pyrroles] by Reaction of Pyrrolo[1,2-c][4,1]benzoxazepinetriones with 2-Aminobenzenethiol

Russian Journal of Organic Chemistry - 3-Aroylpyrrolo[1,2-c][4,1]benzoxazepine-1,2,4-triones reacted with 2-aminobenzenethiol to give...     

Synthesis,crystal structure and photo-induced isomerization of [ N,N ′- bis (4-fluorobenzylidene) ethylenediamine]bromo(triphenylphosphine)copper(I) complex

Abstract

The electrochemical behavior of VOQ₂OH or [VOQ₂-OVOQ₂] (Q = 8-hydroxyquinohnate anion) has been investigated by cyclic voltammetry in acetonitnie solutions. Although both species exist simultaneously at every condition analyzed, they can be clearly differentiated by this method. The effect of trace amounts of water on the electrochemical behavior is also discussed.     

Synthesis and Crystal Structure of 4,4′-(4-(1-Naphthyl)-4-phenyl- 1,3-butadienylidene)-bis[N,N-diethylbenzenamine]

The title compound (C40H42N2) has been synthesized by the reaction of 1-(1-naphthyl)-1-phenyl-3-chloropropylene and bis(4-(diethylamino) phenyl)methanone, and characterized by IR, 1H NMR, MS and X-ray diffraction analysis. The crystal belongs to the monoclinic system, space group P21/c with a = 17.047(3), b = 10.807(2), c = 1&494(4) (A), β = 105.727(4)°, V=3279.4(11) A3, Mr = 550.76, Z = 4, Dc = 1.115 g/cm3, μ(MoKα) = 0.085 mm-1, F(000) = 1184, the final R = 0.0625 and wR = 0.1384 for 2276 observed reflections (I ＞ 2σ(Ⅰ)). X-ray analysis reveals that the butadiene fragment adopts a planar cisiod conformation and makes a dihedral angel of 69.4(2)° with the naphthalene ring.     

Synthesis of 4,4′-bipentacyclo[5.4.0.02,6.03,10.05,9]undecane

A new bi-cage hydrocarbon, 4,4′-bipentacyclo[5.4.0.0^2,6.0^3,10.0^5,9]undecane (12) was designed based on a strategy to construct two cages simultaneously from one key molecule scaffold. Thus 12 was conveniently synthesized from 5,5′-bi(cyclopentadiene) (9) through a three steps synthetic route in 23% overall yield. The new bi-cage hydrocarbon has high density (1.2322 g/cm³) and high volumetric heat of combustion (51.670 MJ/L).     

Synthesis and structure of manganese(ii) coordination polymers with 1,4-diazabicyclo[2.2.2]octane N,N′-dioxide: solvent and template effects

Russian Chemical Bulletin - New metal-organic frameworks [Mn(DMF)2(odabco)2](ClO4)2 · H2O (1), [Mn(H2O)2? (HCOO)2] · odabco (2), and [Mn(Hodabco)2(odabco)3](NO3)4 (3) were...     

Synthesis and Crystal Structure of Dibromo [1,1′- bis(diphenylphosphino)ferrocene]cadmium(II)

1 INTRODUCTION The transition metal complexes containing ferrocene ligand arouse the interest of chemists because of their novel structures and special properties[1]. The ferrocene derivatives have been used in electrochemistry, in nonlinear optics, and as molecular ferromagnets. Some complexes of 1,1′-bis(diphenylphosphino)ferrocene (dppf) have been synthesized, and many of their crystal structures have been reported by far[2~5]. Here we report the synthesis and crystal structure of a …     

Synthesis,characterization and nucleolytic property of bis(N,N′-dimethylglycinato)copper(II)

Aquabis(N,N-dimethylglycinato)copper(II) dihydrate, [Cu(dmg)₂(H₂O)]·2H₂O, has been synthesized and characterized by elemental analysis, FT-IR, magnetic data, thermal analysis, solution UV-visible spectroscopy, X-ray crystal structure analysis and electrospray ionization mass spectroscopy. The square pyramidal copper(II) complex crystallizes in the orthorhombic space group P2₁2₁2₁. The complex cleaves circular plasmid DNA (pBR322) in the presence of H₂O₂. The extent of cleavage varies with the concentration range of the complex, the type of buffer used, pH of buffer and the concentration of H₂O₂. Hydroxyl radical scavenger can inhibit the nucleolytic ability of this complex.     

Synthesis of New 1,3‐bis(Heteroaryl)‐4,5‐imidazolidinediones Through Reaction of N,N′‐bis(Heteroaryl)methanediamines with Oxalyl Chloride

Reaction of N,N′‐bis(2‐pyridinyl, 3‐pyridinyl, 4‐pyridinyl, 2‐thiazolyl, 4‐nitrophenyl, and 2‐benzothiazolyl)methanediamines 1a–f with oxalyl chloride in dry dichloroethane in the presence of pyridine affords the corresponding 1,3‐bis (heteroaryl)‐4,5‐imidazolidinediones 3a–f in good to excellent yields. The essential role of pyridine in the reaction mixture is described, and reaction details as well as product characterization is discussed.     

A Large-Scale Synthesis of Spiro [Cyclopropane-1,9′- [9H] Fluorene] and Derivatives

Our studies of the conjugative properties of cyclopropanes required the synthesis of large quantities of spiro [cyclopropane-1,9′- [9H] fluorene] (1) and its derivatives.¹ The method of Corey² is suited for the preparation of modest (1–5 g) amounts of 1 in one step. This procedure has failed to produce the desired cyclopropane when applied to substituted fluorenones.³     

Synthesis, crystal structure, and thermal properties of N,N′-di(diethoxythiophosphoryl)-1,4-phenylenediamine

The title compound N,N′-di(diethoxythiophosphoryl)-1,4-phenyl-enediamine was synthesized by the reaction of diethoxythiophosphoryl chloride with p-phenylenediamine and characterized by elemental analysis, IR, and ¹H NMR spectra. Its crystal structure was determined by X-ray diffraction analysis and the thermal property was studied by TG analysis. The relative molecular weight of the title compound is 412.42. The crystal structure belongs to the orthorhombic, Pbca space group, with a = 0.86936(16) nm, b = 1.2787(2) nm, c = 1.8897(3) nm, β = 90°, V = 2.1006(7) nm³, Z = 8, Dc = 1.304 g/cm³, μ(Mo Kα) = 0.425 mm⁻¹, F(000) = 872, S = 1.052, the final R = 0.0628 and wR = 0.1860 for 1852 observed reflections with I>2σ(I). The X-ray diffraction analysis demonstrates that the crystal structure is centrosymmetric. The weak N-H⋯S intramolecular hydrogen bonds were observed to link the molecules into sheets. The TG analysis shows that the title compound has good thermal stability and char forming capability and its fire retardation for polyacrylonitrile reveals that the compound is an excellent intumescent fire retardant. __________ Translated from Acta Chimica Sinica, 2007, 65(18): 2034–2038 [译自: 化学学报]     

Synthesis and characterization of optically active poly(amide-imide)s based on [N,N′-(4,4′-carbonyldiphtaloyl)-bis-lamino diacid]s and 1,5-bis(4-aminophenyl)penta-1,4-dien-3-one

Six dicarboxylic acids 3a-3f were synthesized by the reaction of 3,3’,4,4’-benzophenonetetracarboxylic dianhydride 1 with L-aminoacids 2a-2f in a solution of glacial acetic acid/pyridine(Py) at refluxing temperature.Then six new poly(amide-imide)s PAIs were synthesized from the direct polycondensation reaction of[N,N’-(4,4’- carbonyldiphtaloyl)-bis-L-amino diacid]s with 1,5-bis(4-aminophenyl)penta-1,4-dien-3-one(APPD).The polymerization reactions produced a series of new optically active PAIs with high yield and good inherent viscosity.Also these PAIs are optically active and soluble in various organic solvents.These resulting new polymers can be used in column chromatography for the separation of enantiomeric mixtures.The resulted polymers were fully characterized by means of FTIR and ~1H-NMR spectroscopy,elemental analyses,inherent viscosity measurements,solubility tests and thermogravimetric analysis(TGA).     

Synthesis of Bisindolylindeno[1,2-b]quinoxaline and Bisindolylindeno[3,4-b]pyrazine with Poly(N,N′-dibromo-N-ethylnaphthyl-2,7-disulfonamide)

Poly(N,N′-dibromo-N-ethylnaphthyl-2,7-disulfonamide) (PBNS) as novel reagent was synthesized. Bisindolylindeno[1,2-b]quinoxaline and bisindolylindeno[3,4-b]pyrazine derivatives were synthesized in a simple and efficient method from the three-component condensation reaction of indole, indane-1,2,3-trione, and diamine aromatic compounds by PBNS under solvent-free conditions at 80 °C in good to excellent yields, short reaction times, and a simple procedure for new derivatives.

[Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications^® for the following free supplemental resource(s): Full experimental and spectral details.]