共查询到20条相似文献,搜索用时 187 毫秒
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Mei-Huey Lin Chung-Kai KuoWei-Cheng Lin Yen-Chih HuangYu-Ting Tsai Kung-Yu LiangYi-Syuan Li Tsung-Hsun Chuang 《Tetrahedron》2013
A method is described for carrying out indium-mediated allylation reactions of phenacyl bromides in aqueous solution that form homoallylic bromohydrins. By employing subsequent base treatment, the homoallylic bromohydrins were converted to allylic epoxides. Finally, the process has been used as a key step in a concise sequence for the synthesis of 3-allylbenzofuran. 相似文献
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Diastereoselective allylation of imine derived from N‐glyoxyloyl camphorpyrazolidinone and amines was treated with allyltributylstannane in the presence of triflic acid. The corresponding optically enriched homoallylic amines were obtained in reasonable to high material yields and with practical levels of stereoselectivity in 10 min at ambient temperature. 相似文献
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Biswanath Das Keetha Laxminarayana B. Ravikanth B. Ramarao 《Tetrahedron letters》2006,47(51):9103-9106
The allylation of aldehydes and imines has efficiently been carried out by treatment with allyltributylstannane in the presence of a catalytic amount of 2,4,6-trichloro-1,3,5-triazine at room temperature to form the corresponding homoallylic alcohols and amines, respectively, in high yields. 相似文献
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Balin Kumar BhuyanArun Jyoti Borah Kula Kamal SenapatiProdeep Phukan 《Tetrahedron letters》2011,52(21):2649-2651
Titanium exchanged ZSM-5 catalyst has been prepared by treating an aqueous solution of titanium (IV) chloride with ZSM-5. The supported catalyst has been explored as effective and reusable catalyst for allylation reaction of aldehydes with allyltributylstannane. The new catalytic system promotes efficiently the allylation reaction in toluene condition to produce homoallylic alcohols in high yield. 相似文献
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The Barbier type allylation of carbonyl compounds is a useful organic transformation as the resultant homoallylic alcohols are important building blocks for many biologically active molecules. Tin mediated Barbier allylation of different carbonyl compounds in room temperature ionic liquid, [BMIM][BF4] afforded the corresponding homoallylic alcohols in good to excellent yields. The ionic liquid was successfully recycled and reused in allylation reactions. 相似文献
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Indium mediated allylation, crotylation and cinnamylation of benzoins and its substituted derivatives in THF-H2O (2/1) provide a range of homoallylic alcohols. In general, the benzoins undergo allylation and crotylation in a sluggish manner compared to those observed earlier in the case of α-hydroxy aldehydes and are significantly affected by the electronic features of both the benzoin and indium organometallic reagent. The reactions exhibit higher order of diastereoselectivities than those observed for α-hydroxy aldehydes. The cinnamylation though proceeds in a highly diastereoselective manner but is restricted to only benzoin and 4,4′-dichlorobenzoin. The homoallylic alcohols undergo I2 mediated intramolecular diastereoselective cyclization to provide 2,3-diphenyltetrahydrofuran derivatives. The relative stereochemistries in tetrahydrofurans and homoallylic alcohols have been assigned by coupling constants, NOE experiments and in one case by X-ray crystallography. 相似文献
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Ruo‐Qing Wang Chong Shen Xiang Cheng Zuo‐Fei Wang Hai‐Yan Tao Xiu‐Qin Dong Chun‐Jiang Wang 《中国化学》2020,38(8):807-811
Sequential Ir‐catalyzed asymmetric allylation/2‐aza‐Cope rearrangement of arylidene aminomalonates with allylic carbonates was successfully developed, and a variety of enantioenriched homoallylic amine derivatives were obtained in high yields with good chirality transfer and excellent E/Z‐geometry control (up to 99% yield, 96% ee). Compared with previous dual catalytic system established for this transformation, the current mono metal catalytic system provides a simpler and more practical protocol employing the readily available starting materials. 相似文献
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Zhong‐Lin Tao Alafate Adili Hong‐Cheng Shen Zhi‐Yong Han Liu‐Zhu Gong 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2016,128(13):4394-4398
A highly selective multicomponent carbonyl allylation reaction of 1,3‐butadienes, aryldiazonium tetrafluoroborates, and aldehydes has been established under the combined catalysis of palladium acetate and chiral anion phase transfer to render the favorable assembly of chiral Z‐configured homoallylic alcohols in high yields and with excellent levels of enantioselectivity. 相似文献
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Biswanath Das Gandham Satyalakshmi Kanaparthy Suneel Boddu Shashikanth 《Tetrahedron letters》2008,49(50):7209-7212
Three-component reactions of nitroarenes, benzaldehydes, and allyltributylstannane using indium in dilute aqueous HCl at room temperature afford the corresponding homoallylic amines in high yields within 5-10 min. The conversion in one-pot synthesis involves the following steps: (i) reduction of nitro compounds to amines, (ii) formation of imines from amines and aldehydes, and (iii) allylation of imines. 相似文献