共查询到20条相似文献,搜索用时 0 毫秒
1.
YU Yuna LIN Li-Rongb① HUANG Rong-Binb a 《结构化学》2006,25(10):1197-1202
1 INTRODUCTION Recently, for the fluorescent properties, Schiff base has been more and more important and widely studied in density optical memories, nonlinear op- tics (NLO), organic light-emitting diodes (OLED), polymer LED and electrogenerated chemilumines- cence (ECL)[1~5]. Thiosemicarbazones are a kind of Schiff bases with thiourea and good ligands easily chelating with transition metal ions. Although they have been studied extensively for a long time due to their chemical and b… 相似文献
2.
Russian Chemical Bulletin - New 4-dimethylamino-2-(naphthalen-1-yl)-1-phenyl-1-(quinolin-3-yl)butan-2-ols with antituberculosis activity were synthesized.... 相似文献
3.
SHEN Ru-Wei YANG Yu-Zhu CAO Jian WU Lu-Ling HUANG Xian 《结构化学》2007,26(12):1505-1508
The title compound 4-bromo-5-ethoxy-3-methyl-5-(naphthalen-1-yl)-1-tosyl-1H- pyrrol-2(5H)-one 1 (C24H22BrNO4S, Mr = 500.40) has been synthesized and its crystal structure was determined by single-crystal X-ray diffraction analysis. It crystallizes in monoclinic, space group P21/n with a = 8.8562(15), b = 18.118(3), c = 14.055(2) , β = 99.855(3)o, V = 2221.9(6) 3, Z = 4, Dc = 1.496 g/cm3, μ = 1.975 mm-1, λ = 0.71073 , F(000) = 1024, R = 0.0607 and wR = 0.1371. 相似文献
4.
5.
R. R. Gataullin R. R. Ishberdina A. M. Sotnikov I. B. Abdrakhmanov 《Russian Journal of Applied Chemistry》2005,78(3):438-440
Alkenylation of 6-methyl-2-(2-cyclohexen-1-yl)- and 2-(1-cyclohexen-1-yl)anilines with piperylene in the presence of AlCl3 and transformation of the resulting cyclohexenylanilines into carbazole structures were studied.__________Translated from Zhurnal Prikladnoi Khimii, Vol. 78, No. 3, 2005, pp. 441–443.Original Russian Text Copyright © 2005 by Gataullin, Ishberdina, Sotnikov, Abdrakhmanov. 相似文献
6.
Reactions of 3-methyl-6-[4-(4-hydroxyphenyl)-1-piperazinyl]-2(3H)-benzoxazolone, 3-methyl-6-[4-(4-hydroxy-phenyl)-1-piperazinyl]-2(3H)-benzothiazolone and 1,3-dimethyl-5-[4-(4-hydroxyphenyl)-1-piperazinyl]-2(3H)-benzimidazolone with cis-{[2-(2,4-dichlorophenyl) -2-(1H-imidazol-1-ylmethyl)]-1,3-dioxolan-4-yl}methyl meth-anesulfonate in the presence of sodium hydride furnish the title compounds. 相似文献
7.
8.
9.
《Arabian Journal of Chemistry》2014,7(4):418-424
In the present study o-phenylenediamine and naphtene-1-acetic acid/2-naphthoxyacetic acid were used as a starting material through a series of steps and 2-(naphthalen-1-ylmethyl/Naphthalen-2-yloxymethyl)-1H-benzimidazol-1-yl]acetohydrazide 5a, 5b were obtained. In the first series 1,3,4-oxadiazole derivatives have been synthesized from Schiff base of the corresponding hydrazide i.e. 2-[2-(naphthalen-1-ylmethyl)-1H-benzimidazol-1-yl]acetohydrazide 5a by using Chloramin-T. In the second series 1,3,4-oxadiazole has been synthesized from 2-{2-[(naphthalen-2-yloxy)methyl]-1Hbenzimidazol-1-yl}acetohydrazide 5b by using phosphorous oxychloride and aromatic acid. These compounds were evaluated by IR, NMR, Mass spectrometry, elemental analysis and finally in vitro anticancer evaluation was carried out by NCI 60 Cell screen at a single high dose (10–5 M) on various panel/cell lines. One compound 7c was found to be the most active on breast cancer cell line and compounds 4b and 7d were moderately active. 相似文献
10.
Benson M. Kariuki Bakr F. Abdel-Wahab Hanan A. Mohamed Mohamed S. Bekheit Gamal A. El-Hiti 《Molecules (Basel, Switzerland)》2022,27(24)
Reactions of 1-(5-methyl)-1H-1,2,3-triazol-4-yl)ethan-1-ones and benzaldehydes in ethanol under basic conditions gave the corresponding chalcones. Reactions of the chalcones combined with thiosemicarbazide in dry ethanol containing sodium hydroxide afforded the corresponding pyrazolin-N-thioamides. Reactions of the synthesized pyrazolin-N-thioamides and several ketones (namely, ethyl 2-chloro-3-oxobutanoate, 2-bromoacetylbenzofuran, and hydrazonoyl chloride) gave the corresponding novel 2-(1,2,3-triazol-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazoles in high yields (77–90%). Additionally, 2-(4,5-dihydro-1H-pyrazol-1-yl)-4-(1H-1,2,3-triazol-4-yl)thiazoles were obtained in high yields (84–87%) from reactions with N-pyrazoline-thioamides and 4-bromoacetyl-1,2,3-triazoles under basic conditions. The structures of six of the newly synthesized heterocycles were confirmed by X-ray crystallography. 相似文献
11.
Russian Journal of Organic Chemistry - One-pot condensation of pyrazole-4-carbaldehydes with o-phenylenediamine in the presence of chloro(trimethyl)silane (pyridine, 90°C, ambient air)... 相似文献
12.
2-(2,4-二氟苯基)-1-(4-烃基派嗪-1-基)-3-(1,2,4-三唑-1-基)-2-丙醇类化合物的合成及抗真菌活性 总被引:1,自引:0,他引:1
近20年来,真菌感染特别是深部真菌感染日益引起人们的广泛关注[1]。三唑类抗真菌药物对真菌的选择性较高,代谢稳定,体内动态、安全性都较好,已成为目前抗真菌药物研究开发的重点[2]。三唑类抗真菌药物是细胞色素P450 14α 去甲基酶的抑制剂,可影响该酶所催化的真菌麦角甾醇的生物合成,导致真菌细胞膜破损而死亡[3,4]。1998年,SynPhar实验室及Taiho制药公司[5]研制开发的化合物Syn 2869采用了取代哌嗪作为侧链。体外实验表明,该化合物抗菌谱广,对多种念珠菌、隐球菌及曲莓菌均有效,体内实验中,与目前临床上治疗真菌感染的主要用药伊曲… 相似文献
13.
A. D. Vikrishchuk L. D. Popov N. I. Vikrishchuk P. G. Morozov I. E. Mikhailov 《Russian Journal of General Chemistry》2011,81(1):132-134
Recyclization of 4-oxo-1,3-benzoxazinium perchlorates by the action of benzothiazolylhydrazine gave previously unknown benzothiazolyl-substituted 1,2,4-triazoles that attract interest as potential biologically active substances. The structure of the isolated compounds was determined on the basis of their IR and 1H and 13C NMR spectra. 相似文献
14.
15.
Ganushchak N. I. Romanyuk A. L. Litvin B. L. Lys R. I. Polishchuk O. P. 《Russian Journal of General Chemistry》2001,71(2):286-289
2,3-Bis(benzotriazol-1-yl)-1,4-naphthoquinone reacts with aliphatic and aromatic amines to give the corresponding 2-amino-3-(benzotriazol-1yl)-1,4-naphthoquinones, and its reaction with alkali gives 2-hydroxy-3-(benzotriazol-1-yl)-1,4-naphthoquinone. 相似文献
16.
17.
I. B. Dzvinchuk 《Chemistry of Heterocyclic Compounds》2005,41(9):1186-1188
We have developed a convenient preparative method for synthesis of previously unknown 2-(1,2,3-thiadiazol-5-yl)-1H-benzimidazoles
based on reaction of benzoylhydrazones of 2-acylmethyl-1H-benzimidazoles with thionyl chloride.
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1391–1393, September, 2005. 相似文献
18.
G. I. Tsypin T. F. Sharamet T. A. Kravchenko M. S. Pevzner 《Chemistry of Heterocyclic Compounds》1980,16(2):199-201
1-(1,2,4-Triazol-3-yl)-1,2,3-triazoles were obtained by 1,3-dipolar cycloaddition of 3-azido-1,2,4-triazole to acetylene derivatives.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 262–264, February, 1980. 相似文献
19.
Krasnov V. P. Vigorov A. Yu. Nizova I. A. Grishakov A. N. Evstigneeva N. G. Kodess M. I. 《Russian Chemical Bulletin》2004,53(6):1327-1330
The reaction of dimethyl (2S,4RS)-N-phthaloyl-4-bromoglutamate with 2-methylindoline afforded diastereomeric 4-(2-methylindolin-1-yl)-(S)-glutamic acid derivatives, whose oxidation gave rise to 4-(2-methylindol-1-yl)-(S)-glutamic acid derivatives. 相似文献
20.
WAN Jun LI Chun-li LI Xue-mei ZHANG Shu-sheng~ College of Chemistry Molecular Engineering Qingdao University of Science Technology Qingdao P.R. China 《高等学校化学研究》2006,22(4)
IntroductionTriazole derivatives have become the most rapidlyexpanding group of antifungal compounds with advanta-ges of lowtoxicity, high oral bioavailability and broad-spectrum antifungal activity, which can be used againstfungi including most yeasts an… 相似文献