共查询到20条相似文献,搜索用时 62 毫秒
1.
M. Madesclaire V. P. Zaitsev J. V. Zaitseva S. Kh. Sharipova 《Chemistry of Heterocyclic Compounds》2007,43(10):1325-1332
A synthesis is reported for (4R,5R)-and (4S,5S)-4-hydroxymethyl-5-(4-nitrophenyl)oxazolidin-2-ones and (1′R,4R)-and (1′S,4S)-4-[hydroxy(4-nitrophenyl)methyl]oxazolidin-2-ones from (1R,2R)-and (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediols. The effect of the experimental conditions on the formation of these compounds
was studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1562–1570, October, 2007. 相似文献
2.
V. F. Mironov L. M. Burnaeva I. A. Litvinov Yu. Yu. Kotorova A. B Dobrynin R. Z. Musin I. V. Konovalova 《Russian Chemical Bulletin》2004,53(8):1704-1710
The reaction of the di-O-trimethylsilyl derivative of 2-hydroxynicotinic acid with methyl phosphodichloridite afforded 2-methoxy-1,3,2-dioxaphosphorino[4,5-b]pyridin-4(4H )-one. The NMR spectrkscopic data suggest that the reaction of the latter with hexafluoroacetone produces unstable 2-methoxy-2,5-dioxo-4,4-bis(trifluoromethyl)-4,5-dihydro-1,3,2-dioxaphosphepino[4,5-b]pyridine, which is readily transformed into 9-methyl-2,5-dioxo-4,4- bis(trifluoromethyl)-4,5-dihydro-1,3,2-dioxaphosphepino[4,5-b]pyrid-9-inium-2-oate. The structure of the hydrolysis product of the latter, viz., 1-methyl-3-(2-hydroxy-3,3,3-trifluoro-2- trifluoromethylpropanoyl)pyridin-2-one, was established by X-ray diffraction analysis.Published in Russian in Izvestiya Akademii Nauk.
Seriya Khimicheskaya, No. 8, pp. 1640–1646, August, 2004. 相似文献
3.
I. I. Ponomarev D. Yu. Razorenov D. S. Perekalin P. V. Petrovskii Z. A. Starikova 《Russian Chemical Bulletin》2007,56(1):154-159
The reaction of 2-methyl-3-(4-tolyl)-4(3H)-quinazolone with benzil produces 2-[(Z)-3-oxo-2,3-diphenylprop-1-enyl]-3-(4-tolyl)-4(3H)-quinazolone, which is readily transformed into 2-(3,3-diphenylsuccinimido)-N-(4-tolyl)benzamide on dissolution in organic water-containing solvents. The rearrangement mechanism was suggested and investigated
by the quantum chemical PM3 method.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 146–151, January, 2007. 相似文献
4.
V. Yu. Korotaev Yu. A. Skorik A. Yu. Barkov M. I. Kodess A. Ya. Zapevalov 《Russian Chemical Bulletin》2005,54(11):2545-2549
3,3,3-Trifluoro-N′-(3-trifluoromethylphenyl)-1,2-propanediamine (5) was synthesized by the reaction of 2-diazo-1,1,1-trifluoro-3-nitropropane or 3,3,3-trifluoro-1-nitropropene with 3-aminobenzotrifluoride
followed by the reduction of the nitro group. The Michael 1,4-addition of diamine 5 to acrylic acid occurs only at the N(1) atom and affords N-mono-or N,N-dicarboxyethyl derivatives 6 and 7, depending on the reactant ratio. Protolytic equilibria 5–7 in aqueous solutions were studied by pH-potentiometry and UV spectroscopy. Only the aliphatic amino group can be protonated
in an aqueous solution, while the aromatic amino group remains unprotonated even in 12 M HCl. The stability constants of transition metal (Cu2+, Ni2+, Zn2+) complexes with ligands 5–7 were determined by pH-potentiometric titration. The stability of the complexes and selectivity of the ligands toward Cu2+ ions increase with an increase in the number of N-carboxyethyl groups.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2465–2469, November, 2005. 相似文献
5.
Addition of HCl to 2-amino-3-(4-methyl-3-oxopentynyl)-1,4-naphthoquinone in CHCl3 at 20 °C is followed by its cyclization to 4-chloro-2-isopropylbenzo[g]quinoline-5,10-dione. Chlorine atom in this compound can be easily replaced by dialkylamino group upon treatment with secondary
amines. 4-Dialkylamino-2-isopropylbenzo[g]quinoline-5,10-dione is also formed by the direct reaction of the starting ketone with secondary amines. Syntheses of 2-amino-3-(4-methyl-3-oxopentynyl)-1,4-naphthoquinone
from 2-bromo-and 2-amino-3-iodo-1,4-naphthoquinones are also described.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2381–2385, December, 2007. 相似文献
6.
K. A. Frolov V. V. Dotsenko S. G. Krivokolysko A. N. Chernega V. P. Litvinov 《Russian Chemical Bulletin》2005,54(5):1340-1342
Reduction of (E)-3-aryl-2-(4-arylthiazol-2-yl)acrylonitriles with lithium aluminum hydride in dry ether afforded (Z)-1-amino-3-aryl-2-(thiazol-2-yl)prop-1-ene derivatives in 15 to 40% yields. The structure of (Z)-1-amino-3-(2-chlorophenyl)-2-[4-(4-methylphenyl)thiazol-2-yl]prop-1-ene was confirmed by X-ray diffraction analysis.
Dedicated to Academician N. K. Kochetkov on the occasion of his 90th birthday.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1301–1303, May, 2005. 相似文献
7.
V. N. Britsun A. N. Borisevich L. S. Samoylenko A. N. Chernega M. O. Lozynskii 《Russian Chemical Bulletin》2005,54(3):770-773
Oxalylation of 3-oxo-N-phenyl-3-R-propanethioamides in aprotic solvents in the temperature range from −40°C to +20°C results in 4-acyl-5-phenylamino-2,3-dihydrothiophene-2,3-diones and 2-(2-oxo-2-R-ethylidene)-3-phenyl-1,3-thiazolidine-4,5-diones, while in the presence of potassium carbonate, potassium 4-acyl-2,3-dioxo-1-phenyl-2,3-dihydro-1H-pyrrole-5-thiolates are formed.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 757-760, March, 2005. 相似文献
8.
V. Ya. Sosnovskikh M. A. Barabanov B. I. Usachev R. A. Irgashev V. S. Moshkin 《Russian Chemical Bulletin》2005,54(12):2846-2850
Condensation of 4-acetyl-5-hydroxy-3-methyl-1-phenylpyrazole with RFCO2Et (RF = CF2H, CF3) in the presence of LiH affords 4-di(tri)fluoroacetoacetyl-5-hydroxy-3-methyl-1-phenylpyrazoles from which 6-di(tri)fluoromethyl-and
5-di(tri)fluoroacetyl-3-methyl-1-phenylpyrano[2,3-c]pyrazol-4(1H)-ones were synthesized. The reactions of pyrano-pyrazoles with hydrazine hydrate, ethyl mercaptoacetate, or aromatic amines
proceed at the C(6) atom with pyrone ring opening and formation of aminoenones, pyrazoles, or thiophenes with the 5-hydroxy-3-methyl-1-phenyl-4-pyrazolyl
fragment.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2750–2754, December, 2005. 相似文献
9.
Krisztián Bogár 《Central European Journal of Chemistry》2005,3(1):63-71
(R, R)-(−)-N, N′-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) was encapsulated into MCM-22 using the zeolite synthesis method. The
encapsulated catalyst proved to be active in the oxidation of α-methylstyrene with NaOCl with higher specific activity than
the homogeneous catalyst. At the same time, this encapsulated catalyst was completely inactive in the hydrolytic kinetic resolution
of racemic styrene oxide. This observation is in a good correlation with the assumption of the cooperative bimetallic mechanism
proposed by Annis and Jacobsen. 相似文献
10.
Wanxing Wei Yuanjiang Pan Yaozu Chen Cuiwu Lin Tengyou Wei Shukai Zhao 《Chemistry of Natural Compounds》2005,41(1):17-21
Five compounds, terephthalic acid mono-[2-(4-carboxy-phenoxycarbonyl)-vinyl] ester (1), (E)-3-(5′-hydroperoxy-2,2′-dihydroxy[1,1′-biphenyl]-4-yl)-2-propenoic acid (2), 3,4,5-trihydroxybenzoic acid (3), succinic acid (or butanedioic acid) (4), and 2,3,4,5,6-pentahydroxybenzoic acid (5), were isolated from Phyllanthus urinaria. The structures of these compounds were elucidated by means of spectral techniques including IR, MS, and 1D/2D NMR. 1 and 2 are new compounds.__________Published in Khimiya Prirodnykh Soedinenii, No. 1, pp. 14–17, January–February, 2005. 相似文献
11.
V. V. Barbakadze E. P. Kemertelidze I. Targamadze K. Mulkidzhanyan J. Kemink A. J. J. van den Berg K. J. Beukelman A. I. Usov 《Chemistry of Natural Compounds》2005,41(4):374-377
Two high-molecular-weight (>1000 kDa) water-soluble preparations were isolated from stems of Symphytum asperum and S. caucasicum. Their basic component was established as poly[hydroxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene], analogous to that of high-molecular-weight
(>1000 kDa) preparations from roots of these same plants, using IR and NMR spectral data.
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Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 303–305, July–August, 2005.
An erratum to this article is available at . 相似文献
12.
D. V. Shishkin E. R. Mukhamed’yarova N. Z. Baibulatova V. A. Dokichev Yu. V. Tomilov 《Chemistry of Natural Compounds》2007,43(3):293-297
Diastereomers of N-(2-(1-adamantyl)-2-hydroxyethyl)cytisine were synthesized by reduction of N-(2-(1-adamantyl)-2-oxoethyl)cytisine with NaBH4. Their structures were established using x-ray structure analysis.
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Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 244–247, May–June, 2007. 相似文献
13.
2-Polyfluoroalkylchromene-4(4H)-thiones, synthesized from 2-polyfluoroalkylchromones and P2S5, react with aniline, phenylhydrazines, and hydroxylamine at the C(4) atom and afford corresponding anils, phenylhydrazones, and oximes of chromones. On heating in alcohol in the presence of concentrated HCl, chromone phenylhydrazones and oximes undergo ring closure to form 3-(2-hydroxyaryl)-1-phenyl-5-polyfluoroalkylpyrazoles and 5-hydroxy-3-(2-hydroxyaryl)-5-polyfluoroalkyl-Δ2-isoxazolines.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2188–2195, October, 2004. 相似文献
14.
E. B. Tsupak M. A. Shevchenko V. V. Kostrub Yu. N. Tkachenko 《Russian Chemical Bulletin》2007,56(11):2330-2336
5-Aroyl-1,3,6-trimethyluracils were converted to pyrano[4,3-d]pyrimidinium salts. Reactions of the salts obtained with ammonia, primary amines, and hydrazine were studied.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2251–2257, November, 2007. 相似文献
15.
Vera L. M. Silva Artur M. S. Silva Diana C. G. A. Pinto Nadine Jagerovic Luis F. Callado José A. S. Cavaleiro José Elguero 《Monatshefte für Chemie / Chemical Monthly》2007,138(8):797-811
Summary. The syntheses of several new 3- and 5-(4-chloro-2-hydroxyphenyl)-5- and -3-(2,4-dichlorophenyl)-1-alkylpyrazoles are reported.
These syntheses started from simple chlorophenols, 2,4-dichlorobenzaldehyde or ethyl 2,4-dichlorobenzoate in order to prepare
pyrazoles bearing three and four chloro substituents in certain positions. The affinity of these compounds towards the CB
1 type cannabinoids receptors was then evaluated in human brain tissues (frontal cortex). The results showed that some of the
compounds exhibit affinity towards this kind of receptors in the micromolar range. 相似文献
16.
A new method is proposed for the synthesis of indole derivatives containing a chiral substituent at the nitrogen atom, which
includes the direct alkylation of indole derivatives with tert-butyl (2S)-(p-tolylsulfonyloxy)propionate, obtained from commercial
ethyl (S)-lactate with subsequent conversion to the corresponding p-toluenesulfonyloxy derivative by hydrolysis, and esterification.
Dedicated to Academician B. A. Trofimov on his 70th birthday.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, 1391–1398, September, 2008. 相似文献
17.
Substituted benz[g]indole-6,9-diones were synthesized by intramolecular cyclization of 6-alkynyl-5-amino-3-diethylamino-1,-4-naphthoquinones. A method was developed for the preparation of 2-aryl(or alkyl)-4,9-bis(dialkylamino)benzo[h]quinoline-7,10-diones, which involves the addition of a secondary amine to 6-acylethynyl-5-amino-3-diethylamino-1,-4-naphthoquinone followed by cyclization of the resulting adduct.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 412–418, February, 2005. 相似文献
18.
I. M. Aladzheva O. V. Bykhovskaya P. V. Petrovskii K. A. Lyssenko M. Yu. Antipin T. A. Mastryukova 《Russian Chemical Bulletin》2005,54(11):2635-2641
A facile method was developed for the synthesis of N-(3-phosphonopropyl)-substituted α-amino acids and their phosphine oxide analogs based on hydrolysis of 2-oxo-1,2-azaphospholanes
and 1,2-azaphospholanium salts prepared from readily available reagents. A chelate CuII
N-[(3-diphenylphosphoryl)propyl]glycinate was isolated.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2551–2556, November, 2005. 相似文献
19.
I. M. Chung H. Y. Park S. C. Chun J. J. Kim A. Ahmad 《Chemistry of Natural Compounds》2007,43(4):417-421
Three new compounds, 4-hydroxymethylene-7-(9,9,13-trimethylcyclohexyl)-heptanyl-3′,7′,7′-trimethylcyclohexa-2′,4′-dien-1′-oate
(1), 1-(n-hexadec-7-enoxy)-6-(n-octadecanoxy)-β-D-glucopyranoside (2), and (Z)-12-hydroxy-9-octadecenoic acid-12-β-D-glucopyranoside (3), along with the known compound hexacosanoic acid (4), were isolated and identified from the rice hulls of Oryza sativa. Their structures were elucidated by 1D and 2D NMR spectroscopic techniques (1H-1H COSY, 1H-13C HETCOR, DEPT) aided by EIMS, FABMS, HRFABMS, and IR spectra.
Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 344–347, July–August, 2007. 相似文献
20.
D. V. Shishkin A. R. Shaimuratova A. N. Lobov N. Z. Baibulatova L. V. Spirikhin M. S. Yunusov N. S. Makara N. Zh. Baschenko V. A. Dokichev 《Chemistry of Natural Compounds》2007,43(2):190-196
Derivatives of N-(2-hydroxyethyl)cytisine, N-(2-hydroxypropyl)-, N-(2-hydroxy-2-(1-adamantyl)ethyl)-, and N-(2-hydroxy-2-phenylethyl)cytisine, were synthesized by reduction of N-(2-oxopropyl)-, N-(2-oxo-2-(1-adamantyl)ethyl)-and N-(2-oxo-2-phenylethyl)cytisine with metal hydrides. The antiarrhythmic and analgesic activities of the prepared compounds
were investigated.
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Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 157–162, March–April, 2007. 相似文献