共查询到11条相似文献,搜索用时 62 毫秒
1.
2.
Jinzhong Xu Feng Qiu Wenjuan Duan Gexia Qu Naili Wang Xinsheng Yao 《Frontiers of Chemistry in China》2006,1(3):320-323
Three new constituents were isolated from Eleutherine americana Merr. et K. Heyne (hong-cong) by means of silica gel, octadecyl silane (ODS) column chromatography and high-performance liquid
chromatography (HPLC). They were identified as (1) 9,9′-dihydroxy-8,8′-dimethoxy-1′-dimethyl-1H, 1H′-[4,4′]bis[naphtha[2,3-c]
funanyl]-3,3′-dione; (2) 6,8-dihydroxy-3,4-dimethoxy-1-methyl-anthraquin-one-2-carboxylic acid methyl ester; and (3) 2-acetyl-3,6,8-trihydroxy-1-methyl
anthraquinone by the physico-chemical properties and spectral data, respectively. All three compounds showed weak activities
against the growth of Pyricularia oryzea. The minimum morphological deformation concentration (MMDC) was 145.8, 50.2, and 124.8 μg/mL. Additionally, (2) also inhibited
the proliferation of human erythroleukemia cancer cell line K562 with IC50 value of 49.1 μg/mL.
__________
Translated from Chemical Journal of Chinese Universities, 2005, 26(11) (in Chinese) 相似文献
3.
Markus Ganzera Ivo Nischang Christian Siegl Birgit Senzenberger Frantisek Svec Hermann Stuppner 《Electrophoresis》2009,30(21):3757-3763
Two microscale separation techniques for the analysis of bioactive naphthoquinones in Eleutherine americana were developed and validated. By MEKC four compounds (eleuthoside B, isoeleutherin, eleutherol and eleutherinoside A) could be determined in plant extracts using an aqueous electrolyte solution composed of 25 mM sodium tetraborate, 50 mM sodium cholate and 20% THF. CEC on a polymeric methacrylate‐based monolith with strong cationic properties showed promising results, as it additionally enabled the separation of two enantiomers, eleutherin and isoeleutherin. The mobile phase for CEC experiments comprised 3 mM ammonium formate in a mixture of ACN and water. At an applied voltage of ?25 kV, all five markers were baseline separated in less than 12 min. Both methods were successfully validated for linearity (MEKC: R2≥0.999; CEC: R2≥0.997), sensitivity (MEKC: LOD=4–5 μg/mL; CEC: LOD=2–8 μg/mL), accuracy (MEKC: 96.5–102.7% recovery; CEC: 97.1–103.5% recovery) and precision (MEKC: σrel≤2.43%; CEC: σrel≤2.21%). The quantitative analysis of naphthoquinone derivatives in several E. americana samples showed that both methods are suitable for practical applications, because the results were well comparable to those obtained by established techniques such as HPLC. 相似文献
4.
5.
A New Furostanol Saponin from Dioscorea futshauensis 总被引:1,自引:0,他引:1
A new furostanol saponin presenting moderate bioacitivity of inducting morphological deformation of Pyricularia oryzae mycelia was isolated from Dioscorea futshauensis R.Kunth by bioacitivity-guided fractionation. The structure was established as 26-O-β-D-glucopyranosyl-3β,26-diol-23(S)-methoxyl-(25R)-furost-5,20(22)-diene-3-O-[α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl(1→3)]-β-D-glucopyranoside on the basis of chemical evidencesand spectral analysis,especially by 2D-NMR techniques. 相似文献
6.
ChongRenYANG XiKuiLIU JianMingJIN 《中国化学快报》2002,13(12):1189-1192
A new minor pregane glycoside was isolated from the fermented leaves of Agave americana.Its structure was elucidated as (20S)-5α-pregnane-3β,20-diol 20-O-β-D-glucopyrano-side(1)by spectral methods. 相似文献
7.
Victoria Mae Tsuruzaki Shinkai Izana Marize Oliveira Sampaio Eline Gomes dos Santos Adan Jesús Galu-Parra Dionisia Pelaes Ferreira Drielly Dayanne Monteiro Santos Baliza Neidiane Farias Ramos Raphael Sanzio Pimenta Rommel Mario Rodriguez Burbano Chubert Bernardo Castro Sena Barbarella Matos Macchi Irlon Maciel Ferreira Edilene Oliveira Silva Jos Luiz Martins do Nascimento 《Molecules (Basel, Switzerland)》2022,27(24)
8.
A New Spirostanol Saponin from Dioscorea futshauensis 总被引:1,自引:0,他引:1
Hong Wei LIU Hisayoshi KOBAYASHI Ge Xia QU Xin Sheng YAO* Department of Natural Products Chemistry Shenyang Pharmaceutical University Shenyang Institute of Molecular & Cellular Biosciences The University of Tokyo Tokyo Japan 《中国化学快报》2001,(7)
A new screening bioassay detecting deformation of mycelia germinated from conidia of Pyricularia oryzae P-2b was first developed for quantitative application to screen antifungal and antineoplastic agents by H. Kobayashi1,2. We have introduced and applied this bioassay in the search of bioactive agents from Traditional Chinese Medicine3,4. The ethanol extract of Dioscorea futshauensis R. Kunth (Dioscoreaceae) showed a strong activity against the growth of Pyricularia oryzae P-2b. Its buta… 相似文献
9.
Two new spirostanol glycosides named agamenoside A and B, ere isolated from the fermented leaves of Agave americana. Their structures were elucidated as (23S,25R)-5α-spirostan-3β,6α,23-triol 3-O-α-L-rhamnopyranosyl-(1→3)-β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside(1) and (25R)-5α-spiro-stan-3β,6α-diol 3-O-β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyra-nosyl-(1→4)-β-D-galactopyranoside(2) by a combination of chemical and spectral methods. 相似文献
10.
Hai Jiang Wen-Jing Man A-Jiao Hou Lin Yang Xu-Dong Xing Mei-Ling Yan 《Natural product research》2020,34(12):1743-1749
AbstractSix compounds including three new polyketide ones named eleubosas A-C (1–3) were isolated from the active frations of Eleutherine bulbosa. Their structures were elucidated by extensive spectroscopic methods, including NMR, MS and IR spectroscopic analyses data. All the isolates were evaluated against three pathogenic bacteria, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa, and the results showed that compounds 1 and 2 displayed moderate inhibitory activities against E. coli with MIC values both 12.5?μg/mL, which are consistent with the clinical applications and need further studies. 相似文献
11.
Hong Wei LIU Xin Sheng YAO Nai Li WANG Guo Ping CAI 《中国化学快报》2006,17(2):211-214
The Aesculus genus consists of about thirty species distributed in Asia, Europe andAmerica. There are sixteen species distributed in China, and most of them are used asherbal medicines for the treatment of distention and pain in the chest and abdomen. Anu… 相似文献