A chemical study of the roots ofFerula kopetdagensis

Summary Ferukrin and the new natural compound acetylferukrin C₂₆H₃₄O₆ have been isolated from the roots ofFerula kopetdagensis.The absolute configuration of ferukrin has been established on the basis of the results of a study of chemical and spectral characteristics and also by means of a passage to farnesiferol A.It has been shown that it is an epimer of deacetylkellerin at C₆.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 17–21, January–February, 1979.     

General characteristics of the polysaccharides of brown algae

Summary From an acetonic extract of the roots ofFerula samarcandica Kor. have been isolated farnesiferol A, gummosin, and two new coumarin substances, samarcandin C₂₄H_30–32O₅ and samarcandone C₂₄H_28–30O₅. Samarcandin has been converted into samarcandone and their probable structures-I and II-have been established.Khimiya Prirodnykh Soedinenii, Vol. 4, No. 2, pp. 73–77, 1968     

Coumarins of Ferula kopetdaghensis and the structure of kopeolin and kopeoside

Summary The roots ofFerula kopetdaghensis Eug. Kor. have yielded five coumarins — umbelliferone and four new compounds (kopetin, kopeodin, kopeolin, and kopeoside).On the basis of NMR, mass, and IR spectroscopy, derivatives, and transformation products, the structures of two of the new coumarins kopeolin and kopeoside have been established. It has been shown that kopeolin is a derivative of farnesiferol C and kopeoside is kopeolin 3-O--D-glucoside.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 308–313, May–June, 1973.     

The structure of gummosin

Summary From the neutral fraction of an acetone extract of the roots of plants of the genusFerula,F. gummosa Boiss.,F. pseudoreoselinum Rgl. et Schmalh. (K-Pol.) andF. Samarkandica Eug. Kor., we have isolated a coumarin gummosin with the composition C₂₄H₃₀O₄, mp 176–177°C, [a]_D –54°C. The structure of gummosin corresponds to formula (III).With respect to structure, gummosin is a spatial isomer of farnesiferol A; it differs from the latter by the fact that the secondary OH group in gummosin is axial.Khimiya Prirodynkh Soedinenii, Vol. 2, No. 6, pp. 383–387, 1966     

A new terpenoid coumarin fromFerula kopetdaghensis

From the roots ofFerula kopetdaghensis Eug. Kor. have been isolated nevskin and isosamarcandin and a new terpenoid coumarin kopeolone, C₂₄H₃₀O₅, M⁺ 398, mp 125–126°C, [α]_D ¹⁸ +70° (c 0.1, ethanol). On the basis of UV, IR, PMR, and mass spectrometry, and also of transformation into farnesiferols B and C, the configurations of kopeolone, kopeolin, kopeoside, fekrol, kopetdaghin, and fekolin have been established. The configuration of farnesiferol C suggested previously has been confirmed.     

A new acid from the oil of the seeds of Sambucus nigra

Summary A new keto hydroxy acid (I) C₁₈H₃₀O₆ has been isolated from the fatty oil of the seeds ofSambucus nigra in an amount of 2% of the total fatty acids. A study of its chemical properties and spectral characteristics has shown that it is probably 11-hydroxy-9,15,16-trioxooctadeconoic acid, and that it consists of a keto-enol mixture containing about 30% of the two equiprobable tautomers (II and III); it has been given the name of caprifolonic acid.Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 3–8, January–February, 1972.     

Chemical investigation of the polysaccharides of the leaves ofPlantago major L.

Summary 1. Pectic acid contains galacturonic acid (78–83%) and, chemically linked with it, the monosaccharides D-galactose, L-arabinose, L-rhamnose, and substance (VIII) and (IX).2. By fractionating the polysaccharide complex of the leavesof Plantago major L. on a DEAE-cellulose column it has been shown that it consists of pectic acid (80–82%), and free galactoraban (5–6%) and galactan (4–5%).Khimiya Prirodnykh Soedinenii, Vol. 1, No. 6, pp. 369–372, 1965.We have used Kertesz's nomenclature of pectic compounds [4].     

Crystal and molecular structures of 1,8-diacetyl-3-methyl-DL-allantoin

DL-Allantoin (I) has been isolated from an alcoholic extract of a marine spongeAxinellidae gen. sp., and derivatives of it have been obtained: 1, 8-diacetyl-DL-allantoin (II) and 1,8-diacetyl-3-methyl-DL-allantoin (III). The crystal and molecular structures of (III) have been established by X-ray structural analysis.Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Branch, USSR Academy of Sciences, Vladivostok. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 422–426, May–June, 1988.     

Chemical investigation of the polysaccharides of the leaves ofPlantago major L.

Summary 1. A polysaccharide has been isolated from the leaves ofPlantage major L. and its monosaccharide composition has been studied.2. It has been established that the polysaccharide investigated contains D-galacturonic acid, D-galactose, D-glucose, D-xylose, L-rhamnose, L-arabinose, a partially methylated galactose, and two unidentified monosaccharides.3. The high content of galacturonic residues (68%) in the polysaccharide enables it to be classified as a pectin.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 5, pp. 297–302, 1965