通塞脉片中10种元素含量测定分析

采用火焰原子吸收分光光度法测定了通塞脉片中钾,镁,铁,钙,铬,锰,镍,镉,铜,铁,锌10种元素的含量,结果表明,通塞脉片中含有丰富的微量,宏量元素。说明该药物的疗效与其元素的含量有一定的关系。     

慢性肺心病患者血清Cu,Zn及Cu/Zn比值的分析研究

分析了65例慢性肺心病患者血清Cu,Zn的含量及Cu/Zn比值，并与健康对照组比较。结果显示，慢性肺心病患者组血清Zn的含量与健康对照组比较有高度显著性差异（P＜0．01），Cu的含是有显著性差异（P＜0．05），Cu/Zn比值有显著性差异（P＜0．05）。提示慢性肺心病与微量元素Cu、Zn元素的含量变化有一定的关系，为研究元素医学与治疗慢性肺心病提供了必要的依据。     

中山市1387名青年学生头发微量元素检测与分析

为了探讨中山市青年学生头发中的微量元素含量,测定了该市来自三个学校的1387名青年学生头发中的锌、铁、铜、钙、阵、锰、铅含量。结果表明,女生与男生的头发锌含量有显著差异（P＜0．05）,女生与男生的头发中钙含量有高度显著差异（P＜0．001）;城区与乡镇的青年学生头发中钙、铜含量有高度显著性差异（P＜001）;父母文化程度高与父母文化低的青年学生头发中钙含量有高度显著性差异（P＜0．01）;在青年学生的年龄、性别、家庭、居住地区等不同的比较中,以发钙值含量差异显著性最高。提示青年学生应注意饮食营养均衡,补充必需的微量元素,加强体育锻炼,对提高体系有一定的意义。     

蛋鸡对日粮镁水平的反应

试验采用玉米-豆饼型试验日粮,高镁组（6000×10-6,MgO）鸡血液中镁含量显著高于中镁组（1200×10-6,MgO）和对照组（0．00×10-6,MgO）（P＜0．05）,中镁组与对照组间无显著差异（P＞0．05）,而血液中其他矿物元素含量三组间无显著差异（P＞0．05）。在肝脏中,高镁组的磷沉积量显著低于中镜组和对照组（P＜0.05）,而中镁组与对照组间无显著差异（P＞0．05）,其他矿物元素沉积量三组间无显著差异（P＞0.05）。在脾脏、肾脏、胰脏中镁、其他矿物元素的含量及沉积量三组间无显著差异（P＞0.05）。肝脏、脾脏、肾脏、胰脏的鲜重三组间无显著差异（P＞0．05）。     

174例男性不育症患者精浆微量元素检测与分析

检测了174例男性不育症患者精浆锌、铁、铅、钙、镁等五种微量元素,以探讨不育症患者精浆微量元素含量与精液质量的关系。结果显示：（1）粘稠性精液组精浆锌含量显著低于正常粘度精液组（P＜0．01）,精浆钙含量低于正常度精液组（P＜0．05）,铁、铅、镁含量无差异（P＜0．05）。（2）无精子及少精子症组精浆铁、钙含量高于精子密度正常组（P＜0．01）,铜含量低于精子密度正常组（P＜0．01）,锌、镁含量无差异（P＜0．05）。（3）精子活动率低下组与正常组浆微量元素含量无差异（P＜0．05）。提示精浆锌、铁、铅、钙等微量元素含量改变是影响精液质量的重要原因之一。精浆镁含量与精液质量似无明显关系。     

食管癌患者肿瘤组织中硒含量的调查测定

应用2，3-二氨基萘荧光测定法对36例食管癌患者癌组织与癌旁组织及血清中硒的含量进行了测定。结果表明，癌组织中硒含量平均为1．325±0．81μg／g干重，癌旁组织为0．893±0．68μg／g干重，两者差异显著（P＜0．05）；血清中硒含量为0.6033±0．0520μmol／L，对照组20例献血员血清为0．8034±0．0650μmol／L，亦有显著性差异（P＜0．05）。提示硒在抗肿瘤的过程中有一定作用。     

冠心病患者血清钙、镁、磷变化的临床分析

为探讨冠心病患者血清钙、镁、磷的变化及其与冠心病的关系,对62例冠心病患者进行了血清钙、镁、磷含量的测定,并与41例健康人测定结果进行了对比分析。结果表明,冠心病组与健康对照组比较,血清钙离子和镁离子的含量均有显著性差异（P〈0．01）,磷无显著性差异（P〉0．05）。提示冠心病患者有血清离子含量的异常改变,主要表现为血清钙离子和镁离子含量的降低。     

乙型肝炎患者血清中SOD与LPO含量分析

为了研究乙型肝炎患者血清中超氧化物歧化酶（SOD）活性水平、过氧化脂质（LPO）含量及其变化规律,应用黄嘌吟氧化酶法和硫代巴比妥酸法测定了53例乙肝患者血清中SOD与LPO含量,其中急性乙型肝炎（急肝）35例,慢性活动性乙型肝炎（慢活肝）18例。结果表明,乙型肝炎患者（包括急肝、慢活肝）血清中SOD的含量高于正常对照组（P＜0．05）,而LPO的含量也高于对照组（P＜0．01）,具有显著性差异,提示乙型肝炎患者体内存在着自由基紊乱。     

铬强化饲料喂养鸭的实验观察

用三氯化铬强化饲料喂养鸭,剂量从小到大。观察不同剂量所致器官性损害的效应关系及各脏器组织铬蓄积情况。对照组分别与实验组各组相比较,均有显著性差异（P＜0．05）;实验组1与实验组2也有显著性差异（P＜0．05）。鸭体各部位含铬量（10^-6)不同,其顺序是：脑（1．500）＞蛋（0．930）＞胸骨（0．880）＞大腿骨（0．440）＞肾（0．392）＞大腿肉（0．340）＞肠（0．290）＞胸肉（0．255）＞肝（0．180）。     

妊娠糖尿病与非妊娠糖尿病患者头发微量元素含量分析

采用高频等离子体发射光谱法测定了妊娠糖尿病患者、非妊娠糖尿病患者以及相应对照组的头发微量元素锌、铁、铜、锰、锶、镁和常量元素钙的含量。56例健康妊娠妇女的发锌含量为（139．9±31.5）×10－6，而11例妊娠糖尿病妇女为（114．3±29．4）×10－6，两者比较差异有显著性，（P＜0．05），其它元素铁、铜、锰、锶、镁和钙不存在显著性差异。而45例非妊娠糖尿病女性与33名健康非妊娠女性的头发微量元素含量比较表明：两者锌含量不存在显著性差异，但糖尿病组铜显著低于健康对照组（P＜0．05），分别为（6．32±2．31）×10－6和（9．05±16．50）×10－6，糖尿病组铁含量（21．5±11．7）×10－6亦显著低于健康对照组（26．9±10．7）×10－6，其余元素无显著性差异。前后两组实验结果表明妊娠糖尿病患者与非妊娠糖尿病患者的微量元素代谢状况并不相同，妊娠糖尿病患者的锌缺乏状态值得引起注意。     

皮肤病患者血清中铁锌铜锰硒钴含量的研究

１１６例皮肤病患者血清中铁,锌,铜,锰,硒,钴的含量与对照组比较。显示：（１）铁和铜的含量明显升高,硒和钴的含量明显降低,它们之间的差异有高度显著性,Ｐ〈０．０１;锌含量亦降低,两者之间的差异有显著性,Ｐ〈０．０５;锰的含量,两者差异无显著性,Ｐ〉０．０５。（２）可根据上述元素的变化特点,对皮肤病进行早期诊断和治疗。     

脑活素类生物制剂中锰、钴、镍的测定

用火焰原子吸收法直接测定了八种不品牌的脑活素类生物制剂中锰、钴、镍的含量。将七种国产品牌制剂与奥地利脑活素微量元素含量间进行比较,统计结果表明：Ｍｎ,五种差异非常显著,一种差异显著,一种无显著差异,;Ｃｏ,六种差异非常显著,一种无显著差异;     

重度糖尿病患者血清中金属元素钾,钠,钙,镁的分析

对６０例重度中老年糖尿病患者进行了血清中钾、钠、钙、镁的含量测定，并与正常对照组进行了比较。     

肾炎及肾衰患者血中金属元素含量的变化

用原子吸收法或极谱法测定了对例慢性肾炎病人（A组）和24例慢性肾衰病人(B组)及40名健康人（对照组，C组）全血中的Fe、Zn、Cu、Mn、Se、Pb和Ga含量。结果表明，A组与C组比较．血中Fe的含量A组明显低于C组（P＜0.05），Zn、Mn和Se的含量A组均非常明显低于C组（P＜0.01），Pb含量A组非常明显高于C组（P＜0．01），Cu和Ca含量两组间均无明显差异（P＞0.05）；B组与C组比较，Fe含量B组明显低于C组（P＜0.06），Se含量则B组明显高于C组（P＜0.05）；Zn、Mn、Cu、Ga含量B组均非常明显低于C组（P＜0.01），而Pb含量则B组非常明显高于C组（P＜0．01）。     

不同年龄阶段儿童头发锌、铜、铅、镉含量比较

采用电位溶出法检测了９５３例正常儿童发锌,铜,铅,镉含量,得出深圳地区不同年龄组男,女儿童的正常参考值,同时对各元素进行了年龄组间及性别间的比较。结果显示,除发锌无显著性别差异外,男童发铜,铅,镉含量显著高于女童（Ｐ〈０．０５或Ｐ〈０．０１）,随着年龄的增长,儿童发锌含量逐渐上升,而发铜,铅,镉水平逐渐下降。     

Effect of Black Cumin Cake Addition on the Chemical Composition,Glycemic Index,Antioxidant Activity,and Cooking Quality of Durum Wheat Pasta

Pasta is a good carrier for plant enrichment substances due to its popularity among consumers. The purpose of the study was to investigate the functional potential and optimize the recipe of pasta made from durum semolina with the addition of black cumin cake at the level of 5, 10, 15, 20, and 25%. The use of black cumin cake resulted in a statistically significant (p ≤ 0.05) increase in the content of protein, fat, ash, and fiber, including both the insoluble and soluble fractions. A reduction in the digestible carbohydrate content, in vitro starch hydrolysis index (HI), was observed. Pasta with a reduced glycemic index (GI) compared to the semolina control was obtained. The content of polyphenols, including flavonoids, in the cake-enriched pasta increased significantly (p ≤ 0.05), which resulted in higher antioxidant activity against DPPH. The increase in the iron content was over 2.5 times higher in the sample with the 25% addition of black cumin cake than in the control sample. The functional addition significantly (p ≤ 0.05) increased the loss of dry matter and influenced the cooking time of pasta.     

脑血管疾病与慢支肺气肿或并感染患者的头发微量元素测定与讨论

对４６例脑血管疾病、５３例慢支肺气肿或并感染患者进行了头发微量元素的测定及讨论。每组病例铜的含量均低于广州地区正常值，且有高度显著性差异（Ｐ〈０．０１），但脑疾患、肺疾患组铜含量相比较无显著性差异（Ｐ〉０．０５），未看出铜与不同病种的特异性关系。锌含量每组均数都低于广州地区正常值，但只有女性有显著性差异（脑病组Ｐ〈０．０１，肺病组０．０１〈Ｐ〈０．０５），而女性脑病组与肺病组间无显著性差异（Ｐ〉０     

Effect of radiation process on antinutrients and HCl extractability of calcium,phosphorus and iron during processing and storage

Whole and dehulled flours of millet cultivars Ashana and Dembi were stored for 30 and 60 days before and after radiation and/or cooking. Phytic acid and polyphenols contents were assayed for all treatments. The results revealed that the storage period was found to have no effect on phytate and polyphenols contents. Moreover, dehulling of the grains reduced more than 50% of phytate and polyphenols of both cultivars. Cooking of the raw whole and dehulled flour significantly (P≤0.05) reduced phytate and polyphenols contents for both cultivars. Radiation process alone had no effect on phytate and polyphenols contents but when followed by cooking significantly (P≤0.05) reduced the level of such antinutrients for the whole and dehulled flour of both cultivars. Dehulling alone significantly (P≤0.05) decreased Ca and P content but slightly decreased Fe content. Radiation alone or in combination with cooking was found to have slight effect on minerals content of the whole and dehulled raw flour for both cultivars. Cooking alone or in combination with radiation of whole or dehulled raw flour significantly (P≤0.05) improved the extractable Ca but had no significant (P≤0.05) effect on extractable P and Fe for both cultivars.     

Effect of acid and base catalyzed hydrolysis on the yield of phenolics and antioxidant activity of extracts from germinated brown rice (GBR)

The influence of both acidic and basic hydrolysis on the yield, total phenolic content and antioxidative capacity of methanolic extract of germinated brown rice (GBR) was studied. Total phenolic content (TPC), total flavonoid content (TFC), 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical cation scavenging, and ferric reducing antioxidant power (FRAP) tests were used for the measurement of antioxidant ability. There was a significant difference p < 0.05) in the TPC and DPPH radical scavenging assay results when comparing neutral with acidic and basic catalysed hydrolysis. The yield of the crude extract was slightly higher in acidic hydrolysis than in basic hydrolysis p > 0.05). The TPC and TFC were highest in acidic hydrolysis. A significant correlation was observed between ABTS radical cation scavenging and FRAP. The antioxidant activity measured using DPPH radical scavenging assay showed high activity in acidic hydrolysis, while the ABTS radical cationscavenging activity and FRAP showed the highest values in basic hydrolysis. The samples were further evaluated using HPLC to determine the individual phenolic concentrations in different hydrolytic media contributing to the antioxidant effects. This study revealed that acidic and basic hydrolysis can improve the yield, phenolic content, and antioxidant activity of germinated brown rice.