共查询到20条相似文献,搜索用时 31 毫秒
1.
V. A. Mamedov A. A. Kalinin I. Kh. Rizvanov N. M. Azancheev Yu. Ya. Efremov Ya. A. Levin 《Chemistry of Heterocyclic Compounds》2002,38(9):1121-1129
When 3-(a-thiocyanobenzyl-2(1H)-one is heated, competing processes of [a]-annelation of the imidazole or thiazole rings occurs with formation of imidazo[1,5-a]- and thiazolo[3,4-a]quinoxalin-4(5H)-ones. 相似文献
2.
E. Suloeva M. Yure E. Gudriniece S. Belyakov M. Petrova I. Kalnite 《Chemistry of Heterocyclic Compounds》2001,37(3):329-337
Syntheses are reported for a series of 2-alkylamino-6-phenyl-4-trifluoromethylpyridines. The reaction of 3-cyano-2-(hydroxyalkylamino)-6-phenyl-4-trifluoromethylpyridines with thionyl chloride gave the corresponding 2-(chloroalkylamino)pyridines, 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydro-imidazo[1,2-a]pyridines, and 9-cyano-6-phenyl-8-trifluoromethyl-2,3,4-trihydropyrido[1,2-a]-pyrimidines. X-ray diffraction structural analysis was used to study 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine. 相似文献
3.
V. Amankaviciene S. Krikstolaityte A. Sackus 《Chemistry of Heterocyclic Compounds》2002,38(6):686-691
Treatment of 1,2,3,9a-tetrahydro-9H-imidazo- and 1,2,3,4,10,10a-hexahydropyrimido[1,2-a]indol-2-one derivatives with formic acid gave 1-carbamoylalkyl-2,3,3-trimethyl-2,3-dihydro-1H-indoles. 9-Carbamoylmethyl- and 9-(2-carbamoylethyl)-4a-methyl-2,3,4,4a,9,9a-hexahydro-1H-carbazoles were prepared from 5,6,7,7a-tetrahydro-1H,4H-imidazo- and 1,2,6,7,8,8a-hexahydro-5H-pyrimido[2,1-k]carbazolones in a similar manner. Synthesis of 2-(2-carbamoylpropyl)-2,3,3-trimethyl-2,3-dihydro-1H-indole was carried out by reduction of 1,3-dihydrospiro[2H-indolo-2,2'-piperidine] derivative with Zn in acetic acid solution. 相似文献
4.
Condensation of 1-alkyl-, 1-allyl-, and 1-benzyl-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-ones with benzaldehydes in acetic acid and subsequent treatment of the reaction mixture with potassium hydroxide afforded 1-substituted 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one derivatives. 1-Methyl- and 1-ethyl-9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-ones were synthesized by alkylation of 9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one with methyl- and ethyl iodides in DMF in the presence of a strong base. 相似文献
5.
N. E. Golantsov A. V. Karchava V. M. Nosova M. A. Yurovskaya 《Russian Chemical Bulletin》2005,54(1):226-230
4-Substituted 1,2,3,4-tetrahydropyrazino[1,2-a]indoles were synthesized from 2-cyanoindole. (R)-4-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]indole was obtained by the Mitsunobu reaction. Stereoselective reduction of 4-substituted 1,2,3,4-tetrahydropyrazino[1,2-a]indoles gave 4-substituted 1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles. (4R, 10aR)-4-Methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole was synthesized.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 221–225, January, 2005. 相似文献
6.
N. O. Saldabol J. Popelis V. A. Slavinskaya 《Chemistry of Heterocyclic Compounds》2001,37(8):1021-1024
Vilsmeier formylation of 2-(2-furyl)-substituted imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine, and also 6-(2-furyl)imidazo[2,1-b]thiazole with 1 mole of reagent occurs at the free position of the imidazole ring, while with an excess of the reagent it also occurs at the position 5 of the furyl group. 相似文献
7.
S. G. Il'in M. V. Reshetnyak A. I. Yanovskii Yu. T. Struchkov O. Yu. Slabko G. A. Verbitskii V. A. Kaminskii 《Chemistry of Heterocyclic Compounds》2001,37(1):109-119
The spatial configurations of 7,9-diphenyl-5a,6-tetramethylene-5,5a,6,7-tetrahydropyrido[1,2-a]benzimidazole and 7,9-diphenyl-5a,6-tetramethylene-2,5a,6,7-tetrahydropyrido[1,2-a]benzimidazol-2-one have been established by X-ray crystallography. Analogous configurations are proposed for a series of other derivatives of 5,5a,6,7-tetrahydropyrido[1,2-a]benzimidazoles and some derivatives of 6,7-dihydro-5aH-pyrido[1,2-b]benzoxazoles on the basis of 1H NMR spectroscopic data and the results of quantum chemical calculations using the MNDO, AM1, and PM3 methods. 相似文献
8.
V. A. Mamedov E. A. Khafizova E. A. Berdnikov Ya. A. Levin I. Kh. Rizvanov I. Bauer W. D. Habicher 《Russian Chemical Bulletin》2006,55(9):1670-1676
Reactions of methyl chloro(phenyl)pyruvate with 1,3-bis(phenylthioureido)benzene easily afforded 1,3-bis(4-hydroxy-4-methoxycarbonyl-3,5-diphenylthiazolidin-2-ylideneamino)benzene.
Reactions of the latter with 1,2-phenylenediamines gave various derivatives of thiazolo[3,4-a]quinoxalines, including their bisanalogs.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1611–1617, September, 2006. 相似文献
9.
A. A. Bogolyubov N. B. Chernysheva V. V. Semenov 《Chemistry of Heterocyclic Compounds》2004,40(9):1124-1130
4-(Bromomethylene)-5,5-dimethyl-1,3-dioxolan-2-one was obtained on the basis of the readily obtainable 4-methylene-5,5-dimethyl-1,3-dioxolan-2-one. It forms 2-imidazo[1,2-a]pyridin-2-yl-2-propanol with 2-aminopyridine, 11a-hydroxy-1,1-dimethyl-3-oxo-1,5,11,11a-tetrahydro[1,3]oxazolo[3,4-a]pyrido[1,2-d]-10-pyrazinium bromide with 2-(aminomethyl)pyridine, and the corresponding derivative of 4-hydroxyoxazolidin-2-one with 2-(3,4-dimethoxyphenyl)ethylamine. The last product was converted by intramolecular amidoalkylation without isolation into 10b-(bromomethyl)-8,9-dimethoxy-1,1-dimethyl-1,5,6,10b-tetrahydro[1,3]oxazolo[3,4-a]isoquinolin-3-one. 相似文献
10.
V. A. Mamedov D. F. Saifina E. A. Berdnikov I. Kh. Rizvanov 《Russian Chemical Bulletin》2007,56(10):2127-2130
Upon treatment with acetic acid, 3-(2-phenyl-1-selenocyanatoethyl)-, 3-(3-phenyl-1-selenocyanatopropyl)quinoxalin-2(1H)-ones and their thio analogs undergo intramolecular condensation to form selenazolo-and thiazolo[3,4-a]quinoxalines.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2055–2058, October, 2007. 相似文献
11.
12.
M. A. Mzhelskaya I. D. Ivanchikova N. E. Polyakov A. A. Moroz M. S. Shvartsberg 《Russian Chemical Bulletin》2004,53(12):2798-2804
Procedures were developed for the heterocyclization of 2-benzoylethynyl-1-hydroxy-and 1-hydroxy-2-(1-oxo-3-phenylpropynyl)anthraquinone. The regioselective preparation of 2-substituted anthra[1,2-b]pyran-4,7,12-triones was demonstrated to be possible under mild conditions.__________Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2686–2692, December, 2004. 相似文献
13.
L. Yu. Ukhin L. V. Belousova Zh. I. Orlova O. Ya. Borbulevych O. V. Shishkin 《Russian Chemical Bulletin》2000,49(4):732-735
The reactions of 4-morpholino-1,2-naphthoquinone with enamines, cyclohexanone derivatives, afford 7a-amino-5-morpholinohexahydrobenzo[b]naphtho[1,2][1,4]dioxines, while the reaction witho-phenylenediamine yields 5-morpholinobenzo[a]phenazine.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 729–732, April, 2000. 相似文献
14.
V. I. Terenin N. A. Tselishcheva E. V. Kabanova A. P. Pleshkova N. V. Zyk 《Chemistry of Heterocyclic Compounds》2000,36(10):1206-1212
Formylation of 3,4-dihydropyrrolo[1,2-a]pyrazines containing alkyl or aryl substituents at position 1 has been studied under the conditions of the Vilsmeier reaction. The direction of the reaction depends on the structure of 3,4-dihydropyrrolo[1,2-a]pyrazine starting materials. Formylation of 1-methyl-substituted 3,4-dihydropyrrolo[1,2-a]pyrazines occurs at the methyl group. 相似文献
15.
V. I. Terenin E. V. Kabanova N. A. Tselishcheva M. A. Kovalkina A. P. Pleshkova N. V. Zyk 《Chemistry of Heterocyclic Compounds》2004,40(3):351-360
The direction of trifluoroacetylation with trifluoroacetic anhydride of 3,4-dihydropyrrolo[1,2-a]pyrazines containing an alkyl or aralkyl substituent in position 1 depends on both the structure of the 3,4-dihydropyrrolo[1,2-a]pyrazine starting materials and on the ratio of reagent:substrate. It may lead to both mono- and disubstituted products. Trifluoroacetylation of 1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazines occurs at the methyl group. Acetylation of 3,4-dihydropyrrolo[1,2-a]pyrazines leads only to N-acetyl-substituted reaction products. 相似文献
16.
V. P. Kruglenko 《Chemistry of Heterocyclic Compounds》2001,37(4):500-503
The reactions of substituted 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones and -thiones with bromine and N-bromosuccinimide have been studied. Derivatives of 3- and 8-bromo-, 3,8-dibromoimidazo[1,2-b]-1,2,4-triazepine and 5H-2-bromomethyl-3-methyl-7,8-diphenylimidazo[1,2-b]-1,2,4-triazepin-4-one are formed, depending on the degree of substitution, the nature of the brominating agent, and the reaction conditions. 相似文献
17.
Alexander I. Zbruyev 《Tetrahedron》2007,63(20):4297-4303
A convenient and effective synthetic approach to potentially radiochromic polyarene derivatives of bi- and tricyclic aziridines utilizing modified Suzuki-Miyaura cross-coupling with catalysis in micellar media has been developed. A series of polyarene substituents were introduced into 1,5-diaryl-3,5a-dihydro-1H-azireno[1,2-c]imidazoles, 1,6-diaryl-1,3,4,6a-tetrahydroazireno[1,2-a]pyrazines, and 1,2-diaryl-1,1a-dihydroazireno[1,2-a]quinoxalines without degradation of the highly reactive aziridine ring system. 相似文献
18.
I. Ravina D. Zicane M. Petrova E. Gudriniece U. Kalejs 《Chemistry of Heterocyclic Compounds》2002,38(7):836-839
2-Pyridylaminomethyleneisopropylidenemalonates, prepared from ethoxymethyleneisopropylidenemalonate and 2-aminopyridines, form 4-oxo-4H-pyrido[1,2-a]pyrimidines at their melting points and are separated from the reaction mixture by sublimation. 相似文献
19.
J. Suloeva M. Jure E. Gudriniece M. Petrova A. Kemme 《Chemistry of Heterocyclic Compounds》2002,38(6):714-729
The alkylation, acylation, halogenation, nitration, oxidation, and hydrolysis reactions of 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine have been studied. It was found that the 6-halo derivatives add alcohol to give covalent solvates. X-ray analysis has been carried out on one of the solvates (6-chloro-8-cyano-7-ethoxy-5-phenyl-7-trifluoromethyl-1,2,3,7-tetrahydroimidazo[1,2-a]pyridine) as well as on 8-cyano-5-phenyl-7-trifluoromethyl-2,3-dihydroimidazo[1,2-a]pyridine trifluoroacetate. 相似文献
20.
Ahmad Shaabani Ebrahim Soleimani Ali Maleki 《Monatshefte für Chemie / Chemical Monthly》2007,138(1):73-76
Summary. The synthesis of 3-aminoimidazo[1,2-a]pyridines and 3-aminoimidazo[1,2-a]pyrazines through a condensation reaction of 2-aminopyridine or 2-aminopyrazine, aldehyde, and alkyl or aryl isocyanide in
high yields at room temperature in the presence of silica sulfuric acid is described. 相似文献