凤凰木种子毒蛋白的高效凝胶过滤色谱分析

介绍用ＨＰＧＦＣ（高效凝胶过滤色谱）对凤凰木种子中提取的３种毒蛋白分别进行色谱分析。并对分离的蛋白峰进行紫外光谱扫描来确认蛋白的纯度。根椐标准相对分子质量曲线,分别得到它们的相对分子质量并与ＳＤＳ－ＰＡＧＦ（十二烷基磺酸钠－聚丙烯酰胺凝胶电泳）所得结果进行比较,用柱后衍生法测定了３个蛋白各自的氨基酸组成。     

植物白头翁毒蛋白的分离、纯化及其组分测定

植物白头翁（ａｍｅｎｏｎｅ）茎的抽提液经ＣＭ－ＳＦＦ柱和ＳｅｐｈａｃｒｙｌＳ－２００柱分离纯化,得到一种毒蛋白,用高效凝胶蛋白柱和反相高效液相色谱法结合光电二极管阵列检测器确认分离峰的纯度,在高效凝胶蛋白柱上制备了少量毒蛋白纯样,测定了蛋白分子量和氨基酸组成。     

活性碳纤维ZnO—SACF氧化还原机理的研究

本文借助于ＩＲ，ＴＧ和ＸＰＳ，研究了ＺｎＯ－ＳＡＣＦ制备过程中及其吸附Ａｇ＾＋和Ａｕ＾３＋前后的化学结构变化。实验结果表明：从ＳＡＣＦ到ＺｎＯ－ＳＡＣＦ，纤维表面上的Ｏ／Ｃ原子比和含氧基团如Ｃ＝Ｏ和ＣＯＯ都有所减少；ＺｎＯ－ＳＡＣＦ上还原性功能基团主要是－Ｃ－ＯＨ，当ＺｎＯ－ＳＡＣＦ吸附Ａｇ＾＋后，－Ｃ－ＯＨ被氧化为－Ｃ＝Ｏ，而当其吸附Ａｕ＾３＋后，－Ｃ－ＰＨ被氧化为－Ｃ＝Ｏ和－（Ｏ＝Ｃ）－ＯＨ，     

TOTAL SYNTHESIS OF CURVULARIN－TYPE MACROLIDES 12－OXOCURVULARIN AND CITREOFURAN

ＴＯＴＡＬ　ＳＹＮＴＨＥＳＩＳ　ＯＦ　ＣＵＲＶＵＬＡＲＩＮ－ＴＹＰＥ　ＭＡＣＲＯＬＩＤＥＳ　１２－ＯＸＯＣＵＲＶＵＬＡＲＩＮ　ＡＮＤ　ＣＩＴＲＥＯＦＵＲＡＮＴＯＴＡＬＳＹＮＴＨＥＳＩＳＯＦＣＵＲＶＵＬＡＲＩＮ－ＴＹＰＥＭＡＣＲＯＬＩＤＥＳ１２－ＯＸＯ...     

A STREAM-LINED PROCEDURE FOR DETERMINATION OF STARCH,NON-STARCH POLYSACCHARIDES AND FREE SUGARS IN CEREALS

Ａ　ＳＴＲＥＡＭ－ＬＩＮＥＤ　ＰＲＯＣＥＤＵＲＥ　ＦＯＲ　ＤＥＴＥＲＭＩＮＡＴＩＯＮ　ＯＦ　ＳＴＡＲＣＨ，ＮＯＮ－ＳＴＡＲＣＨ　ＰＯＬＹＳＡＣＣＨＡＲＩＤＥＳ　ＡＮＤ　ＦＲＥＥ　ＳＵＧＡＲＳ　ＩＮ　ＣＥＲＥＡＬＳＡＳＴＲＥＡＭ－ＬＩＮＥＤＰＲＯＣＥＤ...     

ZEOLITE－CATALYZED FRIEDEL－CRAFTS ACYLATION OF AROMATICS：I》．SYNTHESIS OF 4－ACYL ANISOLE WITH A HY CATALYST

ＺＥＯＬＩＴＥ－ＣＡＴＡＬＹＺＥＤＦＲＩＥＤＥＬ－ＣＲＡＦＴＳＡＣＹＬＡＴＩＯＮＯＦＡＲＯＭＡＴＩＣＳ：Ｉ．ＳＹＮＴＨＥＳＩＳＯＦ４－ＡＣＹＬＡＮＩＳＯＬＥＷＩＴＨＡＨＹＣＡＴＡＬＹＳＴ￥ＱｉＬｏｎｇＷＡＮＧ；ＹｕＤａｏＭＡ；ＸｉｎｇＤｏｎｇＪＩ；Ｈ...     

CONFORMATION ANALYSIS OF GUANOSINE-5''''-DIPHOSPHO-FUCOSE

ＣＯＮＦＯＲＭＡＴＩＯＮＡＮＡＬＹＳＩＳＯＦＧＵＡＮＯＳＩＮＥ－５＇－ＤＩＰＨＯＳＰＨＯ－ＦＵＣＯＳＥＭｉｎＢｏＣＨＥＮ；ＹｕＬＩＵ；ＺｈｏｎｇＷｕＧＵＯ；ＧｅＱｉｎｇＣＡＩ（ＳｈａｎｇｈａｉＩｎｓｔｉｔｕｔｅｏｆＣｒｇａｎｉｃｏｆＯｒｇａｎｉｃＣｈ...     

ZEOLITE－CATALYZED FRIEDEL－CRAFTS ACYLATION OF AROMATICS∶Ⅲ．SYNTHESIS OF 4－ACYL ANISOLE WITH USY CATALYST

ＺＥＯＬＩＴＥ－ＣＡＴＡＬＹＺＥＤＦＲＩＥＤＥＬ－ＣＲＡＦＴＳＡＣＹＬＡＴＩＯＮＯＦＡＲＯＭＡＴＩＣＳ：Ⅲ．ＳＹＮＴＨＥＳＩＳＯＦ４－ＡＣＹＬＡＮＩＳＯＬＥＷＩＴＨＵＳＹＣＡＴＡＬＹＳＴ￥ＹｕＤａｏＭＡ；ＱｉＬｏｎｇＷＡＮＧ；ＸｉｎｇＤｏｎｇＪＩ；Ｃ...     

FLUORESCENCE STUDIES ON SELF－ASSEMBLING BEHAVIOR OF AMPHIPHILES WITH NAPHALENE－1，5－DIOXY GROUP

ＦＬＵＯＲＥＳＣＥＮＣＥ　ＳＴＵＤＩＥＳ　ＯＮ　ＳＥＬＦ－ＡＳＳＥＭＢＬＩＮＧ　ＢＥＨＡＶＩＯＲ　ＯＦ　ＡＭＰＨＩＰＨＩＬＥＳ　ＷＩＴＨ　ＮＡＰＨＡＬＥＮＥ－１，５－ＤＩＯＸＹ　ＧＲＯＵＰＦＬＵＯＲＥＳＣＥＮＣＥＳＴＵＤＩＥＳＯＮＳＥＬＦ－ＡＳＳＥＭ...     

CATALYTIC PROPERTIES OF SILICA－SUPPORTED POLY－γ－AMINOPROPYLSILOXANE－RHODIUM－COBALT BIMETALLIC COMPLEX FOR HYDROFORMYLATION

ＣＡＴＡＬＹＴＩＣ　ＰＲＯＰＥＲＴＩＥＳ　ＯＦ　ＳＩＬＩＣＡ－ＳＵＰＰＯＲＴＥＤ　ＰＯＬＹ－γ－ＡＭＩＮＯＰＲＯＰＹＬＳＩＬＯＸＡＮＥ－ＲＨＯＤＩＵＭ－ＣＯＢＡＬＴ　ＢＩＭＥＴＡＬＬＩＣ　ＣＯＭＰＬＥＸ　ＦＯＲ　ＨＹＤＲＯＦＯＲＭＹＬＡＴＩＯＮＣＡＴ...     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

KMnO4-mediated oxidative CN bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO₄-mediated oxidative CN bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.     

Chemistry of heterocyclic compounds at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, over 50 years (Review)

The review contains a concise historical account and information on the most significant researches undertaken by the staff at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences on the Chemistry of Heterocyclic Compounds. Dedicated to Academician of the Russian Academy of Sciences B. A. Trofimov on his 70th jubilee. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1443–1502, October, 2008.     

Sulfur-directed metal-free and regiospecific methyl C(sp3)–H imidation of thioanisoles

Regiospecific and direct imidation of the methyl C(sp³)–H bond of thioanisoles is realized under mild and metal-free conditions with N-fluorobis(benzenesulfonyl)imide as an oxidant and nitrogen source. Proposed mechanism suggests that thionium ion intermediates and a Pummerer-type reaction are involved. The imidation has advantages such as high step-economy, excellent functionality tolerance, and regiospecificity, giving structurally diverse imidation products.     

Selective syntheses of 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones via temperature-dependent Rh(II)-carbenoid-mediated 2H-azirine-ring expansion

The Rh(II)-catalyzed reaction of 2-carbonyl-substituted 2H-azirines with ethyl 2-cyano-2-diazoacetate or 2-diazo-3,3,3-trifluoropropionate provides an easy access to 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones. These compounds can be selectively prepared from the same starting material using temperature as the only varied parameter. The 2-azabuta-1,3-diene intermediate, a common precursor for both heterocyclic products, isomerizes into 2H-1,3-oxazine under kinetic control, while 1H-pyrrol-3(2H)-one is the sole product of the reaction at elevated temperatures. According to DFT-calculations a one-atom oxazine ring contraction involving ring-opening to a 2-azabuta-1,3-diene intermediate, followed by a 1,5- and 1,2-prototropic shift leads to the consecutive formation of imidoylketene and azomethine ylide, which then further undergo cyclization to the pyrrole derivative.     

Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives

Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.