共查询到20条相似文献,搜索用时 15 毫秒
1.
Maja Ludvigsen Morten Østergaard Henrik Vorum Christian Jacobsen Bent Honoré 《BMC biochemistry》2009,10(1):34-11
Background
We have previously identified endonuclein as a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas. Now, we aim to investigate its biomedical functions. 相似文献2.
3.
Abstract
An enhanced rate of intramolecular nitrile oxide cycloaddition and hence a rapid synthesis of isoxazoles and isoxazolines is described. Formation of nitrile oxides from oximes using only 1 or 2 Eq (equivalents) of aqueous sodium hypochlorite solution is also described. 相似文献4.
Kiumars Bahrami Mohammad M. Khodaei Akbar Nejati 《Monatshefte für Chemie / Chemical Monthly》2011,15(1):159-162
Abstract
ZnO is an efficient, readily available, and reusable catalyst for the one-pot synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles. This procedure is very simple and affords excellent yields. 相似文献5.
Background
Triptolide is a diterpene triepoxide from the Chinese medicinal plant Tripterygium wilfordii Hook F., with known anti-inflammatory, immunosuppressive and anti-cancer properties. 相似文献6.
Sankareswaran Srimurugan Chi-Ju Su Hun-Chi Shu Kaliyappan Murugan Chinpiao Chen 《Monatshefte für Chemie / Chemical Monthly》2012,14(2):171-174
Abstract
This work describes a convenient and improved process for the synthesis of desomorphine from codeine. The proposed method affords the highly pure opiate without the aid of chromatographic purification, and provides a simple route for the synthesis of [2H3] deuterium-labeled desomorphine. 相似文献7.
Background
Cells expose phosphatidylserine during apoptosis. The voltage across the plasma membrane also decreases or disappears during apoptosis, but the physiological significance of this is unknown. 相似文献8.
Ben-Mei Wei Zhi-Yong Zhang Zhi-Qun Dai Kai-Cheng Zhang 《Monatshefte für Chemie / Chemical Monthly》2011,57(1):1029-1033
Abstract
Dealkylation of esters to carboxylic acids was performed using chloroaluminate ionic liquids (PyHBr/AlCl3, PyHCl/AlCl3, Me3NHCl/AlCl3, Et3NHCl/AlCl3) as catalyst and medium. The catalytic activity of PyHBr/AlCl3 (X(AlCl3) = 0.67) proved to be superior to the other three ionic liquids for the dealkylation of methyl benzoate with a conversion of 97% after 3 h at 140 °C. After easy separation from the products the ionic liquid PyHBr/AlCl3 could be reused six times without loss of its activity. 相似文献9.
Abstract
Stereoselective reaction of various substituted phenols with alkyl propiolates in the presence of a catalytic amount of sodium azide in tert-butyl alcohol at reflux temperature leads to alkyl (Z)-3-phenoxy-2-propenoates in good yields. 相似文献10.
Ahmad Shaabani Afshin Sarvary Sajjad Mousavi-Faraz Seik Weng Ng 《Monatshefte für Chemie / Chemical Monthly》2012,9(5):1061-1065
Abstract
A facile stereoselective synthesis of 1,2-dihydroquinolin-2-ylphosphonate and 1,2-dihydroisoquinolin-1-ylphosphonate derivatives by the three-component reactions of quinoline or isoquinoline, dialkyl acetylenedicarboxylates, and hydrogen phosphonates is described. 相似文献11.
Mohammad M. Ghanbari 《Monatshefte für Chemie / Chemical Monthly》2011,33(5):749-752
Abstract
The adducts produced in the reaction between trialkyl phosphites and acetylenic esters were trapped by thiohydantoins to produce highly functionalized 5-oxo-2-thioxoimidazolidines and 4,5-dihydro-2-(methylthio)-5-oxoimidazoles in good yields. 相似文献12.
Raquel S. G. R. Seixas Artur M. S. Silva Ibon Alkorta José Elguero 《Monatshefte für Chemie / Chemical Monthly》2011,18(5):731-742
Abstract
We report the synthesis and structural study of eight compounds, either quinolin-4(1H)-ones or quinolines. Tautomerism as well as (E) → (Z) and rotational isomerism were studied both experimentally (1H and 13C NMR) and theoretically [B3LYP/6-311++G(d,p)]. 相似文献13.
《Rapid communications in mass spectrometry : RCM》2018,32(2):93-104
Rationale
Li and Mg isotopes are increasingly used as a combined tool within the geosciences. However, established methods require separate sample purification protocols utilising several column separation procedures. This study presents a single‐step cation‐exchange method for quantitative separation of trace levels of Li and Mg from multiple sample matrices.Methods
The column method utilises the macro‐porous AGMP‐50 resin and a high‐aspect ratio column, allowing quantitative separation of Li and Mg from natural waters, sediments, rocks and carbonate matrices following the same elution protocol. High‐precision isotope determination was conducted by multi‐collector inductively coupled plasma mass spectrometry (MC‐ICPMS) on the Thermo Scientific™ NEPTUNE Plus™ fitted with 1013 Ω amplifiers which allow accurate and precise measurements at ion beams ≤0.51 V.Results
Sub‐nanogram Li samples (0.3–0.5 ng) were regularly separated (yielding Mg masses of 1–70 μg) using the presented column method. The total sample consumption during isotopic analysis is <0.5 ng Li and <115 ng Mg with long‐term external 2σ precisions of ±0.39‰ for δ7Li and ±0.07‰ for δ26Mg. The results for geological reference standards and seawater analysed by our method are in excellent agreement with published values despite the order of magnitude lower sample consumption.Conclusions
The possibility of eluting small sample masses and the low analytical sample consumption make this method ideal for samples of limited mass or low Li concentration, such as foraminifera, mineral separates or dilute river waters.14.
Background
Bullfrog myosin-1c contains three previously recognized calmodulin-binding IQ domains (IQ1, IQ2, and IQ3) in its neck region; we identified a fourth IQ domain (IQ4), located immediately adjacent to IQ3. How calmodulin binds to these IQ domains is the subject of this report. 相似文献15.
Boryana Trusheva Ivelin Todorov Mariana Ninova Hristo Najdenski Ali Daneshmand Vassya Bankova 《Chemistry Central journal》2010,4(1):8
Background
Propolis (bee glue) has been used as a remedy since ancient times. Propolis from unexplored regions attracts the attention of scientists in the search for new bioactive molecules. 相似文献16.
Robabeh Baharfar Seyed M. Vahdat Fatemeh G. Hakimabadi 《Monatshefte für Chemie / Chemical Monthly》2009,10(1):489-493
Abstract
An efficient one-pot reaction of dialkyl acetylenedicarboxylates with 2,4-dihydroxybenzo(or aceto)phenones in the presence of triphenylphosphine produces 5-hydroxy- and 7-hydroxycoumarin derivatives. The novel procedure features short reaction time, fairly good yields, and simple workup. 相似文献17.
Nitin A. Randive Varun Kumar Vipin A. Nair 《Monatshefte für Chemie / Chemical Monthly》2010,43(7):1329-1332
Abstract
Water-promoted hydrothiolation and hydroamination of ethyl propiolate leading to highly regioselective and stereoselective formation of thioacrylates and β-enamino esters in excellent yields, by a simple, efficient, and environmentally friendly reaction procedure without employing any hazardous reagent or solvent is reported. 相似文献18.
Abstract
In the current study we relate the contents of the journal of “Structural Chemistry” for the calendar year 2006 to thermochemistry. Each paper is briefly summarized and supplemented by a comment which explicitly interrelates the content of the study to chemical energetics. 相似文献19.
Najmedin Azizi Alireza Khajeh Amiri Roya Baghi Mohammad Bolourtchian Mohammad M. Hashemi 《Monatshefte für Chemie / Chemical Monthly》2009,3(2):1471-1473
Abstract
p-Toluenesulfonic acid (10 mol%) was found to be an effective and efficient catalyst for the synthesis of 2-substituted benzothiazoles from aromatic aldehydes and 2-aminothiophenol in moderate to excellent yields in water. This method provides a simple and efficient protocol in terms of mild reaction conditions, clean reaction profiles, small quantity of catalyst, and simple workup procedure. 相似文献20.
Kurt Kalcher Ivan Svancara Marijo Buzuk Karel Vytras Alain Walcarius 《Monatshefte für Chemie / Chemical Monthly》2009,390(1):861-889