共查询到20条相似文献,搜索用时 15 毫秒
1.
Kuilong Wang Hongli Yu Xinzhi Wang Yaozong Pan Yeqing Chen 《Natural product research》2015,29(15):1456-1460
A new casbane diterpenoid, referred to as pekinenin G, together with one cembrane diterpene and four known casbane diterpenoids were isolated from the roots of Euphorbia pekinensis. Their structures were elucidated on the basis of spectroscopic studies and comparison with related known compounds. The six compounds showed different cytotoxic activities against four human cancer cell lines. 相似文献
2.
Lin-Feng Dai Qian Liang Tie Liu Ming-Yu He Ping Zhao 《Natural product research》2016,30(14):1639-1645
One new tigliane-type diterpene, 4-deoxy-4(β)H-8-hydroperoxyphorbol-12-benzoate-13-isobutyrate (1), together with two known diterpenoids, 3-acetyl-5,8-dibenzoyl-14α-propanoyl-13,17-epoxy-7-myrsinaone diterpene with C9–C10 cyclised to form an additional lactone ring (2), Euphodendriane A (3) have been isolated from the whole plants of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis (NMR and HR-ESI-MS) and comparison with data reported in the literature. This is the first isolation of 8-hydroperoxy tigliane diterpene (1) from the genus of Euphorbia. All compounds were evaluated for their antifungal activities. 相似文献
3.
Muhammad Zahid SyedRaziullah Husani Muhammad Abbas Yuanjiang Pan AmirReza Jassbi Muhammad Asim Masood Parvez Wolfgang Voelter ViqarUddin Ahmad 《Helvetica chimica acta》2001,84(7):1980-1988
A reinvestigation of Euphorbia decipiens with a modified extraction procedure resulted in the isolation and structure elucidation of eight new myrsinane‐type diterpene esters (see 3 – 10 ). Moreover, revised structures are proposed for decipinone B ( 1 ) and C ( 2 ) on the basis of X‐ray‐diffraction analyses. The structures of the compounds were elucidated by means of different spectroscopic methods, including 1D‐ and 2D‐NMR studies. 相似文献
4.
Li Wang Yu-Qian Chi Wen-Bin Ouyang Zhen Zang Sheng-Xiong Huang 《Natural product research》2015,29(15):1406-1413
A new myrsinol-type diterpene polyester, 14-deoxo-3β-O-propinoyl-2α,5α,7β,15β-tetra-O-acetyl-14α-O-benzoyl-myrsinol (1), and its known analogue, 14-deoxo-3β-O-prorionyl-5α,15β-di-O-acetyl-7β-O-nicotinoyl-myrsinol-14β-acetate (2), together with a monoterpenoid, pubinernoid A (3), two indole alkaloids, neoechinulin A (4) and dihydroxyisoechinulin A (5), two benzene derivatives, siringin (6) and (3-methoxyphenyl) acetic acid (7), were isolated from the 70% acetone extract of the aerial parts of Euphorbia dracunculoides Lam. Their structures were elucidated on the basis of spectroscopic evidence and comparison with literature reports. The absolute configuration of 1 was deduced by comparing experimental and calculated ECD spectra. Among them, compounds 4 and 5 were first obtained from the plant source. In addition, the 13C NMR data of compound 2 was reported for the first time. 相似文献
5.
Ahmad VU Hussain J Hussain H Jassbi AR Ullah F Lodhi MA Yasin A Choudhary MI 《Chemical & pharmaceutical bulletin》2003,51(6):719-723
Three new diterpene esters with a myrsinol-type skeleton have been isolated from Euphorbia decipiens BOISS. & BUHSE. The structure elucidation of the isolated compounds was based primarily on two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bond correlation (HMBC) and nuclear Overhauser effect spectroscopy (NOESY) experiments. Compounds 1 and 3 are active against prolyl endopeptidase and compound 2 showed inhibitory activity against urease enzyme. 相似文献
6.
<正>A new lathyrane diterpene glycoside,named 3β,7β,15β-trihydroxy-14-oxolathyra-5E,12E-dienyl-16-O-β-D-glucopyranoside, was isolated from Euphorbia helioscopia L.Its structure was established by spectroscopic techniques including 2D NMR. 相似文献
7.
Yang Qing He Xiao Mei Wei Yi Li Han Li Ming Gao 《中国化学快报》2007,18(5):545-547
Chemical investigation on the ethanol extract from the whole plants of Delphinium chrysotrichum resulted in the isolation of two new diterpene alkaloids named delphatisine A (1) and delphatisine B (2), respectively. The structures of the new compounds were deduced on the basis of their spectral data (IR, HREIMS, EIMS, 1D, 2D-NMR). This is the first report on the isolation of diterpenoid alkaloids from the D. chrysotrichum. 相似文献
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10.
Edvárd SulyokAndrea Vasas Dóra RédeiPeter Forgo Zoltán KeleGyula Pinke Judit Hohmann 《Tetrahedron》2011,67(38):7289-7293
Four new premyrsinane-type diterpenes (1-4) were isolated from the methanol extract of the whole, undried plant of Euphorbia falcata. Their structures were determined by a combination of 1D and 2D NMR (COSY, HMBC, HSQC and NOESY) techniques and mass spectral data as di-, tetra-, penta- and hexaesters of diterpene polyols, esterified with acetic, benzoic, propanoic, isobutanoic and n-hexanoic acids. One of the compounds contains a rare hemiacetal moiety. This type of diterpenes was previously detected only in four Euphorbia species (Euphorbia aleppica, Euphorbia decipiens, Euphorbia macroclada and Euphorbia pithyusa subsp. cupani). 相似文献
11.
Two new myrinsol diterpenoids, euphordracunculins A(1) and B(2), together with three known analogues, euphorprolitherin B(3), proliferins A(4) and B(5),were isolated from the petroleum ether extract of the aerial parts of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis(NMR and ESI-MS) and comparison with data reported in the literature. 相似文献
12.
Zhan Ping Gou Nian Ci Liang Jie Hou Li Li Yan Tian Chang Yuan Wang Xun Cui Bao Jing Zhang Xiao Chi Ma 《中国化学快报》2011,22(12):1451-1453
A new diterpene and a new sesquiterpene were isolated from Pteris dispar and identified on the basis of spectral data including 2D NMR.Compounds 1 and 2 showed potent cytotoxic activity against KB cell. 相似文献
13.
A.G. González G. de la Fuente M. Reina V. Zabel W.H. Watson 《Tetrahedron letters》1980,21(12):1155-1158
Chemical, spectral and X ray data are given for cardiopetaline and cardiopetalidine, two new C-19 diterpene alkaloids from the genus Delphinium. 相似文献
14.
From the flowers of Baccharis medullosa DC (Asteraceae) two new ent-labdane-type diterpene glycosides were isolated. Structures were established by application of various spectroscopic techniques. The sugar residues were identified after acid hydrolysis of the isolated products. 相似文献
15.
Two new beta-dihydroagarofuran sesquiterpene polyesters, 1S,13-diacetyloxy-4S-hydroxy-6R-(3-)furancarbonyloxy-9S-cinnamoyloxy-beta-dihydroagarofuran (1) and 1S,6R-di(2-)methylbutanoyloxy-4S-hydroxy-8S-benzoyloxy-9R-(3-)furancarbonyloxy-13-acetyloxy-beta-dihydroagarofuran (2), together with one known compound (3) were isolated from the seeds of Euonymus nanoides LOES. Their structures were elucidated by spectroscopic data interpretation. Compound 2 showed moderate antitumor activity against BEL-7402, P-388, HL-60 and A-549. 相似文献
16.
Meng Wang Qiuhong Wang Qing Wei Jing Li Chen Guo Bingyou Yang 《Natural product research》2016,30(2):144-149
Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR experiments. X-ray analysis was applied to determine the structure of compound 2. All 13 compounds were screened for cytotoxicity in vitro against human tumour MCF-7, HepG-2 and SGC-7901 cell lines. Compounds 1 and 2 showed the inhibitory effects against MCF-7 with IC50 levels of 23.21 and 15.42 μM; simultaneously, compounds 4, 6, 8 and 11 also had definite inhibitory effect against different cell lines. 相似文献
17.
Dewen Bi Guanghui Xia Yuanping Li Xuesong Liang Lanjun Zhang 《Natural product research》2018,32(8):875-879
Two new cassane ditepenoid lactams, caesmimotam A (1) and B (2), along with eight known compounds (3–10) were isolated from the fruits of Caesalpinia mimosoides Lam. Their structures were identified by 1D and 2D NMR spectral data. Compounds 1 and 2 were evaluated for their cytotoxicity on HL-60, SMMC-7721, A-549, MCF-7 and SW-480 human cancer cell lines, but they were inactive. 相似文献
18.
Margarida Costa Rogelio Fernández Marta Pérez Margrét Thorsteinsdottir 《Natural product research》2020,34(8):1053-1060
AbstractTwo new marine natural compounds, 3β-acetoxy-15-hydroxyspongia-12-en (1) and 3-methylspongia-3,12-dien-16-one (2), were isolated from the marine sponge Acanthodendrilla sp., collected in Pulau-Pulau. Compounds 1 and 2 represent new chemical entities of the known spongian diterpene family. Compound 1 is a new 3-acetoxyspongia and compound 2 presents an unreported rearranged 3-methylspongia-3-en. Their structures, including relative configurations, were fully elucidated based on 1D and 2D NMR analyses, as well as HRESTOFMS experiments. No significant bioactivities were found for these compounds. This work reports two new chemical structures, compounds 1 and 2, together with the first isolation of spongian diterpenes from Acanthodendrilla genus. 相似文献
19.
Demirkiran O Topcu G Hussain J Ahmad VU Choudhary MI 《Magnetic resonance in chemistry : MRC》2011,49(10):673-677
Two new unusual monoterpene glycosides, (Z)-3,6-dimethyl-3-(β-D-O-glucosylmethylene)cyclohept-4-ene-1-one (1) and 3,6-dimethyl-3-(β-D-O-glucosylmethylene)cycloheptanone (2) have been isolated along with five known compounds, 3-hydroxy-4-methoxybenzoic acid, 6,7-dihydroxycoumarin, luteolin, apigenin 5-O-αl-L-rhamnoside, and pinocembrin-7-O-rutinoside from ethyl acetate extract of Euphorbia decipiens. The structures of the isolated compounds were elucidated by extensive 1D- and 2D-NMR, and mass spectroscopic analyses. 相似文献
20.
Daoubi M Benharref A Hernandez-Galán R Macías-Sánchez AJ Collado IG 《Natural product research》2004,18(2):177-181
Two novel steroids, 3beta,7alpha-dihydroxy-4alpha,14alpha-dimethyl-5alpha-cholest-8-en-11-one (2) and 3beta,7beta-dihydroxy-4alpha,14alpha-dimethyl-5alpha-cholest-8-en-11-one (3) were isolated from the latex of Euphorbia officinarum. Their structures were established on the basis of NMR and MS studies. 相似文献