火焰原子吸收光谱法分析中药中锌的形态

采取正辛醇水分配体系模拟中药水煎液中锌在人体胃肠中的分配情况，用原子吸收光谱法测定了十二味中药药材及其水剪液中锌的含量，水煎液中水溶态锌、醇溶态锌的含量。实验结果表明，中药中锌的水煮溶出率较氏，中药中锌的形态与中药成分，配伍情况及作用靶位（胃肠）的酸度有关，酸度及配伍对中药中锌的溶出率及水煎液中锌的形态影响较大。     

测定肺癌患者血清铅,锌及铜锌比值的临床意义

采用原子吸收法测定了６４例肺癌及３１例健康人的血清铅、锌含量，结果表明，肺癌组血清锌低于健康对照组，而血清铜及铜锌比值则高于对照组，差异均非常显著（Ｐ〈０．０１）。按ＴＮＭ分期，Ⅱ￣Ⅲ期肺癌组与Ⅳ期肺癌组血清锌并无差异，但前者血清铜及铜锌比值明显低于后者。若以１．５７为铜锌比值的临界值，则肺癌患者阳性符合率为５１．５６％，高于ＣＥＡ３４．３７％。但不同病理类型间血清铜锌无差异。提示铜、锌及铜锌比值     

锌从土壤向食物链的迁移

锌是生物必需微量元素，但过多时对动植物都有毒害。本文对锌在人类食物链中的行为及在土壤－－植物－－人类和动物系统中的迁移，决定农业系统中锌动力学的关键过程，锌在作物可食部位的丰度，影响锌生物有效性的土壤环境，植物因子及锌在食物中的需要量等作了综述了论述。     

微量元素锌与儿童生长发育

广州市红十字会医院儿科对幼儿园儿童调查发现低锌者达70％，且膳食中锌摄入量仅2．5～5mg／d，提示锌营养不良普遍存在。为此，该科研制了“复锌散”，对缺锌儿童进行治疗及前瞻性研究。对象为幼儿园中3～5岁232名低锌及低锌膳食儿童。     

新婚蜜月宜补锌

锌是人体内必需的微量元素之一；也是生殖细胞代谢不可缺少的营养物质。锌不仅能增加血液中性激素的水平及精子的数量，还有促进性腺分泌的作用。人体内缺乏锌，除影响健康外，也不利于优生。美国研究人员指出，锌与生殖器官、性征及性功能密切相关，缺锌时可发生精子异常、不育及性欲减退甚至阳萎；女性口服避孕药也影响锌的吸收导致不孕症。他们分别对20名新婚男女进行研究，证实了这种观点的正确性。人体所需的锌，平时是由膳食中摄取。     

锌对环磷酰胺引起的小鼠胸腺和脾脏重量变化的影响

应用硫酸锌，复合蛋白锌对环磷酰胺引起的小鼠脾脏及胸腺重量变化的影响进行了观察。结果表明，胸腺微量元素锌含量高于脾脏，复合蛋白锌组胸腺重量及其指数高于环磷酰胺组，与 酸锌组无差异。     

蛋白质、脂肪、碳水化合物对微量元素吸收的影响

蛋白质及氨基酸蛋白质摄入状况不仅直接影响机体的营养状况，而且对宏量或微量元素等营养物的吸收、保持和利用也可产生影响。蛋白分解后生成的组氨酸、胱氨酸、半胱氨酸及谷氨酸，蛋氨酸等均与锌结合而促进其吸收。它们可使粒状不溶性复合物（锌、钙植酸盐）中的锌很容易释放出来。ATRNMO研究发现在包含低锌的情况下，摄入足量的蛋白质及热能，有明显的锌潴留作用。     

类风湿性关节炎血浆置换治疗前后微量元素铜铁锌的变化

采用原子吸收分光光度计，对１５例类风湿性关节炎患者血浆中铜、铁、锌的含量进行测定，并与正常对照组作比较。结果显示患者铜明显升高，锌降低，铜／锌比值升高。血浆置换后铜含量及铜／锌比值恢复正常，锌含量有所恢复。证明类风湿性关节炎患者铜、铁、锌的代谢方面存在一定缺陷。血浆置换可纠正这种微量元素代谢异常，从而起到改善免疫功能的作用。     

肾小球疾病时微量元素代谢的变化

用发射光谱法测定了55倒广州地区居民患肾小球疾病时血清和头发申锌、铜、铁、钴、铬、锰含量，观察对象包括肾病综合征组17例，肾炎组17例，尿毒症组21例．对照组为30例健康人。其年龄、性别构成比、地区与观察组无显著性差异．结果经统计学检验发现肾病综合征组病人血清锌、铜、钴及头发锌、钴含量均明显下降，头发铜无明显变化，肾炎组血清钴、头发钴明显下降，血清锌、铜及头发锌、铜无明显变化。尿毒症组病人血清锌、头发锌、钴显著下降，血清钴、铜及头发铜无明显变化．肾炎组、肾病综合征组及尿毒症组病人血清及头发申铁、铬、锰均无明显变化。     

锌与小儿神经系统及代谢性疾病

综述了锌在小儿神经系统疾病和内分泌代谢性疾病中的作用及临床意义，尤其是对癫痫的发病起重要作用，大量资料证明高锌与癫痫发作有关，其血锌值明显高于健康儿童，因此在治疗中不要轻易补锌。还综述了锌与智能发育障碍、生长发育障碍、多动症、胎儿畸形、遗传性感音神经性聋等疾病的关系及在治疗糖尿病、肝豆状核变性等内分泌和代谢性疾病时要注意维持锌的正常动态平衡。     

水系锌离子二次电池锌负极的研究进展

锌离子二次电池具有优异的充放电性能、高功率密度和能量密度、低成本、高安全性和环境友好的特点,极具发展前景。金属锌,因优异的导电性、低的平衡电势、高的理论比容量和低成本等因素,是水系二次电池中理想的负极材料,然而也存在着枝晶生长、腐蚀和钝化等问题,限制了锌离子二次电池的可逆容量和循环寿命,通过优化调节锌负极的形貌与表面修饰等方法可以提高电池性能。本文综述了水系锌离子二次电池负极材料的研究进展,涵盖了金属锌负极、复合锌负极和锌合金,且展望了锌负极的发展前景。     

锌含量对Zn/HZSM-5催化剂性能的影响

 研究了不同锌含量的Zn／HZSM－5分子筛的表面酸性及其对正己\r\n烷芳构化反应的催化活性、选择性和稳定性．结果表明,锌组元的引入\r\n减少了HZSM－5表面的B酸,增加了L酸,总酸量增大;正己烷转化率随\r\n锌含量的增加先降低后升高;芳烃产率和芳构化选择性则随锌含量的增\r\n加先增大后趋于平缓;反应过程中催化剂的积炭速度、孔体积和比表面\r\n积下降速度都随着锌含量的增加而加快;锌含量大于1％时,Zn／HZSM\r\n－5的催化稳定性不如HZSM－5,且随着锌含量的增加失活速度加快．优\r\n选的锌含量为1．0％～2．9％．此外,讨论了Zn／HZSM－5的催化性能\r\n与其表面性质的关系．     

Parameters affecting carbofuran photocatalytic degradation in water using ZnO nanoparticles

Carbofuran photodegradation in water using zinc oxide nanoparticles as a catalyst was examined as well as some parameters influencing its percentage degradation rate such as zinc oxide load, initial concentration of carbofuran, the temperature of the reaction, the initial pH of the solution, and doping of zinc oxide nanoparticles with 5% (w:w) silver. Zinc oxide and Ag-doped zinc oxide nanoparticles were produced using solvothermal and photoreduction methods, respectively, and silver doping effects on the structural, optical, and photocatalytic properties of zinc oxide nanoparticles were investigated using XRD, UV-VIS spectrophotometer, TEM, SEM, SEM/EDX, and FTIR. The average diameter of the synthesized samples was 26.6, 30.55 nm for undoped zinc oxide and Ag-doped zinc oxide, respectively. Zinc oxide doping with silver did not change the shape of the zinc oxide crystal, but decreased the reflection in the visible region, as well as the energy of the bandgap, and increased the zinc oxide photocatalytic activity.     

花椒中五种微量元素含量的测定

采用原子吸收光谱法,测定了河南太行山区花椒及椒皮、椒籽中锰、铁、铜、锌、铅的含量。结果显示,各元素在实验范围内,线性关系良好,回收率在92%~103%之间。花椒及椒皮、椒籽中均含有微量元素,花椒中锰、铁、铜、锌、铅的含量分别为78.851、90.868、11.571、18.818、0.086μg.g-1,其中锰、铁含量丰富,有害元素铅的含量极低。椒籽中铁、铜、锌的分布量大于椒皮;椒皮中锰的分布量大于椒籽。为探讨花椒的高药用价值提供了有力的证据,椒籽中铜、锌、铁含量高于椒皮,应大力开发利用。     

Light‐Controlled Release and Uptake of Zinc Ions in Solution by a Photochromic Terthiazole‐Based Ligand

We have synthesized and fully characterized a photochromic zinc complex with a terphenylthiazole‐based ligand with a salen‐like cavity. The solution stability of the complex was found to be greatly dependent on the state of the photochromic ligand and an interesting photo‐triggered release and uptake of zinc ions was found as well as monitored by its fluorescence. The contrasting stability difference of the zinc complex between its two isomeric states was rationalized by DFT calculations.     

A Semi-solid Zinc Powder-based Slurry Anode for Advanced Aqueous Zinc-ion Batteries

The booming of aqueous zinc-ion batteries (AZIBs) draws the researchers’ attention to issues of zinc metal anodes, such as uncontrollable dendrite growth, corrosion, and volume effects. Zinc powder anode is more suitable for the industrial application of AZIBs than the widely used zinc foil anode due to its low cost, tunability and processability. However, the related solutions are rarely studied because the above issues of zinc metal anode are more serious in zinc powder anode. Herein, for the first time, we design a semi-solid zinc slurry anode consisting of zinc powder and zincophilic tin additive dispersed in a conductive elastic rheological network. Zinc can be deposited homogeneously on the dispersed tin particles, which avoids agglomerative zinc deposition and alleviates volume change during repeated zinc stripping/plating. Moreover, the practical application of the full cell with slurry is very promising since its operating life can be easily extended by facile slurry renewal.     

新型卟啉化合物的合成及性质

利用微波反应和模板效应合成了带有苯乙烯撑单元的新型卟啉化合物和锌卟啉配合物. 通过 1H NMR, IR和MALDI-TOF-MS等技术对其结构进行了表征. 通过测定UV-Vis和PL对两种卟啉化合物光学性能进行了研究. 利用TGA和循环伏安法研究了锌卟啉配合物的热稳定性和电化学性质, 并以锌卟啉配合物作为掺杂剂利用蒸镀法制备了电致发光器件, EL谱发射峰位于556 nm.     

Zinc in gastrointestinal and liver disease

Zinc is an essential trace element with important biological functions, depending on the structural and/or catalytic role played by zinc ions in a large variety of enzymes. Zinc plays a critical role in cellular integrity, protein synthesis, nucleic acid metabolism, contributing to cell growth, proliferation, differentiation and death. The present review reports data on zinc homeostasis and metabolism, zinc absorption, intercellular trafficking, intracellular transport inside enterocytes and hepatocytes. Particular emphasis is given to data regarding the role of zinc carriers ZnTs and Zips, and to their expression in liver and gut in experimental and in human studies. The role of zinc in the gastrointestinal tract and in the liver as a powerful antioxidant and its relationship with apoptosis is discussed. Possible implications of zinc status in different disorders of the gastrointestinal tract are presented, focusing on its possible introduction in the therapy of inflammatory bowel diseases. Data on the role of zinc and zinc carriers in the evolution of liver fibrosis towards cirrhosis are also discussed. Finally, data on the ability of zinc therapy to obtain regression of liver cirrhosis in patients affected by Wilson's disease are reported, and the hypothesis that zinc could protect against liver fibrosis in chronic liver disease of different origin is presented.     

锌离子荧光探针研究进展

锌广泛存在于人体内,具有重要生理功能。因此,对游离锌离子的选择性识别和有效检测具有重要意义。荧光探针因其设计简单、易于操作、灵敏度高、可细胞成像等诸多优点而广泛应用于锌离子的识别研究。锌离子荧光探针常见的识别机理包括光致电子转移、分子内电荷转移、荧光共振能量转移、聚集诱导荧光增强、螯合荧光增强等。其中,基于螯合荧光增强机理的锌离子探针,其荧光团通常可同时作为识别基团,因此,相比于其它探针,具有设计较为简单、合成较为便捷的优点。本文综述了近年来文献中报道的基于以上各种识别机理的锌离子荧光探针,并着重介绍了螯合荧光增强机理在锌离子识别中的应用。     

SYNTHESIS AND PHOTOCYTOTOXICITY OF SOME NEW SUBSTITUTED PHTHALOCYANINES

Some new, ring-substituted phthalocyanines have been synthesized and underwent preliminary testing for photodynamic activity using the colony forming ability of Chinese hamster cells in culture as an endpoint. Using 4-(3-N,N-diethylaminopropyl)phthalonitrile as a precursor, the previously unknown metal-free 2,9,16,23-tetra-(3-N,N-diethylaminopropyl)phthalocyanine was prepared and converted to its zinc (II) and its cationic water-soluble 2,9,16,23-tetramethylammonium zinc (II) iodide derivatives. Other new phthalocyanine derivatives tested, include a 2,9,16,23-tetra(2-hydroxymethyl-2-methylbutoxy)phthalocyaninato zinc (II) and 2,3,9,10,16,17,23,24-octahydroxyphthalocyaninato zinc (II) derivatives. Boron tribromide cleavage of the newly prepared and fully characterized 2,3,9,10,16,17,23,24-octamethoxyphthalocyanine gave the unstable metal-free octahydroxyphthalocyanine, which could only be characterized by ultraviolet-visible, NMR and IR spectroscopy.