高能质子照相中基于角度准直器设计的理论研究

角度准直器在高能质子照相中有着重要作用,既可以利用准直器提高图像对比度,又能通过二次成像实现材料诊断及密度重建,因此减小通过准直器后通量值的误差具有重要意义.本文通过理论分析,提出了一种高能质子照相中准直器设计的方法,通过Geant4程序建立了1.6 GeV的质子成像系统,该系统分别使用理想准直器、拉伸型准直器和利用该方法设计的准直器,并对比通过客体后的通量分布.结果表明,在使用理想准直器和该方法设计的角度准直器时,二者得到的客体的通量分布符合较好,而使用拉伸型准直器时,与使用理想准直器得到的结果相差较大.因此利用理想准直器方法设计的准直器可以很好地减小通量误差.     

闪光照相中校正准直器的研究

用闪光照相技术诊断内爆动力学实验时，存在着一些难以克服的困难：动态量程约为10^4，散射过强而将信号光束淹没。FTO客体边缘部分是形成客体散射的主要部分，也是动态量程大的主要原因。使用校正准直器具有一举两得的效果：既降低动态量程，又减小客体的散射。后保护器件和客体边缘部分是散射的主要来源。校正准直器的使用，使得入射到后保护器件的直接X射线和散射X射线都减少，有效地降低后保护器件的散射。     

毛细管准直微束过程模拟与微束品质分析

利用GEANT4程序对复旦大学单粒子微束的毛细管准直过程进行了蒙特卡罗模拟。计算结果表明:当前采用的1 m孔径、1 mm长度的毛细玻璃管准直器能够引出峰值能量2.2 MeV、能量分辨130 keV、束径2.4 m的质子微束,可达到装置对微束能量与束径分辨的设计指标,从理论上明确了毛细管准直微束引出的可行性。针对影响入射目标细胞微束品质的主要因素,分析了微束品质与准直系统和入射束流各状态参数的依赖关系,为毛细管准直微束的引出与优化提供了必要的理论依据。     

高能质子照相的成像方程

与X射线闪光照相相比,GeV级质子照相因质子的穿透能力更强而更能满足流体动力学最佳光程、更小不确定度的要求。质子照相用于提取阴影客体信息的过程比X射线闪光照相复杂。为了便于分析质子照相过程及其特性,以质子照相的输运过程为基础,逐步考虑了质子与物质相互作用的各种过程——核反应、多次库仑散射、准弹性散射和弹性散射,并获得含各种过程的质子照相理论计算表达式。在含准直的系统中,理论计算公式中包含了多次弹性散射和准弹性散射项。通过与QMCPrad计算结果的对比得知弹性散射高斯近似下的理论计算结果与蒙特卡罗方法(MC)计算结果一致,与更准确的"黑体"模型的相对误差为3%~5%。这意味着在某种程序上,当研究质子照相规律或设计系统时,高能质子照相的理论计算公式能够替代MC模拟。     

闪光照相系统的散射分布与降散射的数值模拟

 对法国试验客体（FTO）的3 m照相系统建模,利用Monte-Carlo方法模拟X光子输运过程,得到了系统的散射分布和系统器件对散射的贡献。结果表明：后保护锥是系统散射的主要来源,对于任意一点,后保护锥的散射占总散射的75%以上。FTO的散射主要是FTO外层材料和边缘的散射,这部分散射占客体总散射的90%以上。利用坡度准直器对系统散射严重的区域进行的降散射,表明坡度准直器是一个很好的降散射器件,能有效提高图像质量。     

发散型准直器限束孔应用于被动散射质子放疗可行性研究

被动散射质子放疗（Passive Scattering Proton Therapy,PSPT）是质子治疗的主要技术之一,束流通过准直器限束孔（Aperture）时因边缘散射效应导致患者体内剂量分布偏离理想状态。使用蒙特卡洛软件TOPAS（TOol for PArticle Simulation）对质子束流经过发散型与传统型准直器限束孔后进入水模体中的过程建模,分析两种准直器的边缘散射效应对剂量及中子能谱分布的影响,分别测试70,110,160,200,230,250 MeV能量下的质子束流,发现传统Aperture在70 MeV的质子束下边缘散射效应最明显,在距水箱表面0.5 cm深度处横向剂量曲线平坦度、均匀度分别达到4.63%,108.05%,随着深度增加边缘散射效应逐渐减弱,在布拉格峰位置处接近消失。使用发散型准直器限束孔后,在70 MeV下平坦度、均匀度分别降至1.28%,101.31%,对于100,160,200 MeV质子束均有不同程度改善。对于能量接近250 MeV的质子束,发散型准直器限束孔设置下横向剂量曲线并无优势。边缘散射效应导致的剂量不均随水深增加而减弱,对于各个能量质子,使用发散型准直器限束孔后次级中子减少。研究结果表明,发散型准直器限束孔应用于PSPT效果显著,为进一步应用于临床提供数据支撑。Passive Scattering Proton Therapy (PSPT) is one of the main technologies for proton radiation therapy. The dose distribution in the patient deviates from the ideal state due to the edge scattering effect when the beam passes through the aperture. In this paper, TOPAS, a Monte Carlo software, was used to simulate the passive scattering treatment head. The influence of the edge scattering effect of the two aperture sets on the dose distribution was compared. The proton beam at 70, 110, 160, 200, 230 and 250 MeV was tested respectively. We found that the scattering effect of the conventional aperture is most obvious at 70 MeV, and the flatness and hetergeneity of the lateral dose curve at the inlet of 0.5 cm of the tank reach 4.63%, 108.05%, respectively. The dose shift caused by the edge scattering effect decreases with increasing water depth and disappears at the Bragg peak. After using the divergent aperture, the flatness and uniformity at 70 MeV are reduced to 1.28% and 101.31%, respectively, and the 100, 160, and 200 MeV proton beams are improved in different extents. For a proton beam with an energy close to 250 MeV, there is no advantage in the lateral dose curve of the divergent aperture. For all energy protons, the secondary neutrons are reduced with divergent aperture. The results show that the divergent aperture is effective for PSPT and this study provides data support for further application in clinical practice.     

FTO质子照相中扩束器的设计

 为了达到最佳的扩束效果和充分利用束流,从多次库仑散射角、能量损失和透射率这三个方面确定扩束器的材料类型。对均方根多次库仑散射(MCS)、质子能量损失和质子的透过率的研究都表明单位面质量下材料原子序数越大,扩束效果越好。再结合成本和适用性确定扩束器的材料为钨。同时,从探测器接收到的质子通量均匀而噪声影响小的角度,确定了扩束器的厚度。研究结果为：没有准直器的情形下,扩束器的厚度为3.1 cm;准直器角度为3.0 mrad时,扩束器厚度为2.4 cm。     

适用于适形治疗与调强治疗的质子束流配送系统

描述一个适用于适形治疗和调强治疗的散射式质子束流配送系统.它利用双散射系统扩展质子束,利用程序控制的二进制射程调节器和搓板式调制器调节和调制质子射程,利用程序控制的多叶光阑和为每个患者特制的准直器进行束流准直.     

高能电子照相成像模糊模拟研究

高能电子照相是一种新兴的无损探测技术,可以在不拆解客体的情况下对客体材料及其内部结构进行定量测量。与高能质子照相相比,其分辨能力更高,可达到亚m量级,有望成为介观现象诊断的有力工具。为研究相互作用和成像束线对成像模糊度的影响,采用Geant4模拟软件,建立12 GeV电子束从客体到像平面全过程照相模型,主要分析了成像束线引起的色差模糊、客体纵向长度引起的模糊以及次级粒子造成的模糊。研究结果表明,高能电子照相成像模糊为亚m量级,其中成像束线引起的色差模糊为主要贡献项,次级粒子和客体纵向长度引起的模糊可以忽略。     

复合三子镜稀疏孔径光瞳结构的研究

由于在截止频率区域内稀疏孔径系统的调制传递函数(MTF)比全孔径系统的调制传递函数下降,甚至调制传递函数可能出现零点而影响成像质量,通过稀疏孔径系统的结构优化可以获得调制传递函数分布比较理想的孔径结构。给出了基于实际空间截止频率ρR和子孔径直径的稀疏孔径结构优化准则,对复合三子镜稀疏孔径结构进行优化,分析了优化前后的调制传递函数变化,并对优化结构的复合三子镜稀疏孔径系统模拟成像和维纳滤波,比较优化前和优化后稀疏孔径结构的成像情况。结果表明结构优化是稀疏孔径光学系统设计的一个关键部分,应用的优化准则对稀疏孔径结构优化是合理的,通过结构优化可以使复合三子镜稀疏孔径系统的成像质量得到改善。     

Large-aperture double-focus laser collimator for PAT performance testing of inter-satellite laser communication terminal

A laser collimator is necessary for testing and verification of the pointing, acquisition and tracking (PAT) performance of inter-satellite laser communication terminals on the ground. The laser collimator must have a large clear aperture to fit the PAT performance testing system. The PAT subsystem has a large field of view for the acquisition and a high angular accuracy for the fine tracking. To resolve the conflict between large field of view and fine angular resolution, a large-aperture double-focus laser collimator is proposed and its optical design and mechanical structure are described. The collimator mainly consists of a primary lens, a reflector, a beam-splitting plate, a secondary lens, two compensating lenses, two imaging sensors and a laser. The primary lens directly forms the long focal length arm of the collimator. The combination of the primary lens and the secondary lens form the short focal length arm of the collimator. The collimator has an angular resolution <0.75 μrad and a 10 mrad field of view. For the collimator, the incident beam is focused on the two imaging sensors by its two arms, and the beam emitted from the laser is collimated and transmitted. The collimator is combined with an optical scanner and a fine beam deflector to test and verify the PAT performance of the inter-satellite laser communication terminal in a full physical manner.     

Precision magnetic quadrupole lens for a nuclear scanning microprobe based on an ÉGP-10 electrostatic tandem accelerator

Basic ideas underlying the design of a precision magnetic quadrupole lens for a nuclear scanning microprobe with a maximal accelerating voltage of 14 MV are set forth. Four magnetic quadrupoles are combined into doublets. The doublets are placed on adjusting gears, which bring the local coordinate system of each lens into coincidence with the laboratory system related to the axis of the beam. Each lens provides a maximal gradient of the field of 0.68 T/cm, which makes it possible to perform stigmatic focusing of the beam with a working distance of 22 cm. All lenses are nonseparable and made of one piece of high-quality electrical steel. A special lens-feeding unit is designed that provides manual and remote control of pole tip excitation.     

质子照相磁透镜的优化设计

 对质子照相系统中Zumbro磁透镜的参数进行了优化,使成像系统造成的图像模糊最小化,结果表明:构成Zumbro磁透镜的四极透镜对内外漂移段长度相等时,成像系统获得最小的图像模糊。对成像系统的视场进行了分析,表明视场对Zumbro透镜的参数不敏感。给出了质子能量为20 GeV时Zumbro透镜的参数,Geant4蒙特卡罗计算表明:所给的Zumbro透镜参数能正确成像。     

Optimization of the lens-array structure for performance improvement of integral imaging

The seemingly inherent deficiencies of integral imaging systems-in particular, the depth of field limitation-are, in this Letter, partly resolved by using an irregular lens array, where each lens is either rotated or displaced from its original position in the conventional flat lens array. It is shown that having an array of lenses in the integral imaging system has some sort of redundancy that could be exploited to improve the quality of the image formation. The needed rotation or displacement of constituent lenses in the array is found by using a meticulous optimization algorithm, which tries to evenly distribute the optical rays emanating from each of the lenses to form the final image.     

Velocity spectrometer for a neutral atomic beam

A velocity spectrometer for a neutral atomic beam has been developed to prepare a monovelocity atomic beam. In order to disperse a relatively fast atomic beam according to its longitudinal velocity, a magnetic quadrupole lens with a large magnetic gradient has been used. The device was made using NdFeB permanent magnets. The magnetic gradient in the quadrupole was measured to be sufficiently large (1 T/cm) and uniform along the radial direction. The resonance fluorescence spectra of the Li atomic beam after passing through the magnetic quadrupole lens have been measured by using a single-mode tunable laser. From the peak shift of the fluorescence spectrum, the exerted force on Li atoms by the magnetic lens was 8160 times as large as the acceleration of gravity. Using the present spectrometer, we have measured the longitudinal velocity distribution of the thermal Li beam at 800 °C, which was in good agreement with the result from the fluorescence spectra. It is expected that a monovelocity Li atomic beam of 1000 m/s with a velocity spread narrower than 1% can be easily formed with a compact experimental arrangement using the developed velocity spectrometer. In this case, the available flux given as a fraction of the incident Li flux is estimated to be about 1%. A high-velocity resolution of 0.03% is expected at the available fractional flux of about 0.01%. Received: 5 June 2000 / Revised version: 14 August 2000 / Published online: 8 November 2000     

Electron extraction through an objective lens

The laws of electron motion in the field of a combined lens (composed of an electrostatic and magnetic lenses, as in a low-voltage scanning electron microscope) are considered. The character of the secondary- and backscattered-electron trajectories in the collimator field is analyzed taking into account the generalized electron momentum.     

利用准直管法测凹透镜的焦距

介绍了利用准直管精确测量凹透镜焦距的方法，该方法借助一个焦距较长的凸透镜与被测凹透镜组成无焦系统，可以使准直管出射光束的张角发生改变；用一辅助凸透镜与一测微目镜进行平行光束的会聚，测出准直管玻罗板线对在辅助凸透镜焦平面上所成像的大小；经过相应计算可得到被测凹透镜的焦距。     

像方扫描技术研究

基于显微摄影的成像原理,研究了像方扫描以扩大视场的途径,并建立了一个二次成像的设计模型,包括一个大视场的固定前置物镜组和一个运动轨迹为球面的中继透镜组。物镜组所成的一次像面优化了场曲,中继透镜组则根据该场曲进行运动,对一次像面不同区域成像,并采用光学被动消热差以保证不同温度的像质。该模型的相对孔径1∶3,波长3.7 m~4.8 m,焦距90 mm,瞬时凝视视场为4,扫描视场达24,采用7片透镜3个非球面,在全视场范围内具有接近衍射限的像质。     

混合仿生鱼眼-复眼的广角高清成像系统

基于多尺度成像理论,采用混合仿生鱼眼-复眼结构,实现了大视场兼具高分辨率的光学成像系统设计。前级物镜系统为大直径球透镜,收集广角目标光线并成像到与球透镜同心的球面中继像面上;次级目镜系统是关于球透镜中心球对称的小口径透镜组阵列,对中继像进行像差校正并成像到探测器阵列上。对比了物镜采用双层同心球和单个球透镜的成像性能,后者可获得更优的成像性能且避免了双胶合球透镜带来的公差控制及力学与热稳定性问题。整个成像系统的视场大于100°,全视场内角分辨率优于10″,而畸变小于5%;系统具有大景深特点,不需调焦即可同时对300 m到无穷远目标清晰成像,可广泛应用于侦查监控等领域。