New synthetic routes to 1-methyl-1-silaindane (1b) and 1-methyl-1-germaindane (1b) were developed and the desired products were obtained in good isolated yield. Compounds 1a and 1b were fully characterized by mass spectroscopy, 1H and 13C{1H} NMR, and infrared spectroscopy. 相似文献
The Z and E teomers of the title compounds are regioselectivity and stereoselectively prepared respectively by reaction of phosphorus ylides with α-selenocyclopropyl aldehydes and by addition of α-lithio seleno-cyclopropanes on α-seleno aldehydes. 相似文献
The compound 2,4-dichloro-1-pentene-1-d1 ( 1 ) was synthesized starting from and CH?CNa. In the last stage of the synthesis on activated carbon-HgCl2 catalyst), ( 3 ) were formed together with ( 1 ). The NMR parameters of ( 1 ), its cis and trans isomers and ( 2 ) were obtained in C6D6 solution at 100 MHz. Theoretical spectra of ( 1 ) at 60 MHz were simulated with the aid of a computer, using as input the NMR parameters obtained at 100 MHz and good agreement with the experiment was obtained. 相似文献
The thermal decompositions of 1-chloro-1-fluoroethane and 1-chloro-1,1-difluorethane at atmospheric pressure have been studied in the temperature range 500–600°C in a flow system. The dehydrochlorinations are homogenous in a carbonaceous reactor and unimolecular. The rate constants are given by and The criteria for molecular or chain processes in thermal dehydrochlorinations are discussed. 相似文献
Triorganylsiloxy- and triorganylgermoxy-germatranes have been prepared by the interaction of the easily available 1-hydroxygermatrane with various hetaryl-silanes and -germanes. The compounds were of the general structure:
M = Si; X = S, CH = CH (viz. phenyl); n = 0,1,2
M = Ge; X = CH = CH (viz. phenyl); n = 0
All siloxy- and germoxy-germatranes obtained were subjected to psychotropic assays. Some of phenylsiloxygermatranes are effective for memory enhancement (inhibition of retrogradal amnesia by triphenylsiloxygermatrane was 80%). 相似文献
Combretastatins A-1 and B-1 have been synthesized by coupling MOM-protected p-iodomethoxycatechol with 3,4,5-trimethoxyphenylacetylene in a Sonogashira reaction. 相似文献
The aldol dimerization of 1-indanone and 1-tetralones using titanium tetrachloride and triethylamine as condensing agents provides α,β- and β, γ-unsaturated ketones, respectively, in 53–58% yield. 相似文献