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In?vitro antifungal activity and phytochemical constituents of essential oil, aqueous, methanol and chloroform extract of Eucalyptus citriodora Hook leaves were investigated. A qualitative phytochemical analysis was performed for the detection of alkaloids, cardiac glycosides, flavonoids, saponins, sterols, tannins and phenols. Methanolic extract holds all identified biochemical constituents except for the tannin. While these biochemical constituents were found to be absent in essential oil, aqueous and chloroform extracts with the exception of sterols, cardiac glycosides and phenols in essential oil and sterols and phenols in aqueous and chloroform extracts. Antimycotic activity of four fractions of E. citriodora was investigated through agar-well diffusion method against four post-harvest fungi, namely, Aspergillus flavus Link ex Gray, Aspergillus fumigatus Fres., Aspergillus nidulans Eidam ex Win and Aspergillus terreus Thom. The results revealed maximum fungal growth inhibition by methanolic extract (14.5%) followed by essential oil (12.9%), chloroform extract (10.15%) and aqueous extract (10%). 相似文献
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A New Ceramide from the Soft Coral Cladiella humesi Verseveldt 总被引:2,自引:0,他引:2
Ming Yan WANG Yi LUO Jing Yu SU Department of Chemistry Zhongshan University Guangzhou 《中国化学快报》2000,11(9)
Ceramides are increasingly becoming important compounds because of their markedbiological activity. The 2000 International Gordon Research Conference on "Glycolipidand Sphingolipid Biology" will be held in May in italy. It has been recently found thatceramides inhibit Cholesteryl Ester Transfer Protein (CETP)'. Elevation in CETP leadsto atherosclerotic cardiovascular diseases2. A literature survey showed that ceramideswere antifungal', and some of these showed antimicrobial and cytotox… 相似文献
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Two new O‐bearing 4‐methylidene sterols, 9α‐hydroxy‐15‐oxoconicasterol ( 1 ) and 8β‐hydroxy‐B‐norconicasta‐6α‐aldehyde ( 2 ), were isolated from the EtOH extract of the marine sponge Theonella swinhoei collected from the South China Sea. Their structures were elucidated by spectroscopic data and comparison with known compounds. In addition, spectroscopic data reported for the known 4‐methylidene sterol 7α‐hydroxyconicasterol ( 3 ) were revised. 相似文献
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肉芝软珊瑚Sarcophyton crassocaule中新的多羟基甾醇的分离 总被引:1,自引:0,他引:1
报道了从三亚海域的一种肉芝软珊瑚Sarcophyton crassocaule Mosre中分离得到2个多羟基甾醇1和2. 通过波谱分析等方法测定了它们的化学结构, 化合物1为新化合物, 命名为Sarcrasterol. 化合物2为已知物[24ξ-methyl-colestane-3β,5β,6α,25-tetrol], 但其C24构型未确定, 通过X射线单晶衍射分析测定了其相对构型为24S. 相似文献
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The new phytosphingosine‐type ceramide 1 , named paxillamide (=2,3‐dihydroxy‐N‐[(1S,2S,3R)‐2,3‐dihydroxy‐1‐(hydroxymethyl)heptadecyl]tetracosanamide), was isolated from the CHCl3/MeOH extract of the fruiting bodies of the Basidiomycete Paxillus panuoides, and its structure was elucidated by spectroscopic and chemical methods. 相似文献
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D. A. Korzhenevskii V. N. Kuptsov V. A. Mityanina A. A. Selishcheva S. V. Saveliev T. Yu. Kalashnikova 《Journal of Analytical Chemistry》2011,66(13):1270-1275
A preparative separation of total ceramide fraction from the crude extract of the erythrocytary lipids was done by means of normal-phase column chromatography. This was followed by comprehensive profiling of the molecular species in the obtained ceramide by means of HPLC/MS and HPLC/MS/MS. The MS/MS analysis displayed that human erythrocytes contain 19 molecular species of the ceramide of which 12 can be unambiguously identified; erythrocytary ceramides may contain not only sphingosine but also sphinganine as their building blocks; one of the species (namely Cer 24:2/S18) previously has managed to escape identification. We also obtained a quantitative profile of major ceramide species showing the prevalence of Cer 22:0/S18, 24:0/S18 and 24:1/S18. 相似文献