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1.
B. Szargan G. Leonhardt F.U. Flöther A. Meisel 《Spectrochimica Acta Part B: Atomic Spectroscopy》1973,28(9):359-361
The As Lα1,2 and Lβ1 X-ray emission spectra from metallic arsenic and from the compounds As2O3, Na2HAsO4·7H2O, and GaAs were measured with high resolution and fluorescence excitation. The shape of the spectra and correlation between the chemical shifts of the Lα lines (0·1, ? 0·22 and ? 0·05 eV in As2O3, Na2HAsO4·7H2O, and GaAs resp.) and atomic charges are discussed. 相似文献
2.
Very large doses of sodium arsenate (Na2HAsO4), 14 mg As kg?1 of body weight, were administered to Sprague-Dawley male rats (body weight 300 g) fed a 5% Hijiki diet by stomach tube twice within two days. After 24 h, the rats were sacrificed and various organs were dried for subsequent neutron activation analysis. The distribution of arsenic (As) in selected organs was determined by neutron activation analysis. The highest concentration of As was found in blood cells with a rather high concentration in the liver and heart. As the control, rats which were fed on a 5% cellulose diet were used. Control rats which were administered arsenate showed that the arsenic distribution and the concentration in their organs were similar to those on the 5% Hijiki diet. Even the blood cells of the controls without any arsenic administration were found to contain a small amount of arsenic. 相似文献
3.
Experimental results in this paper lead to the following conclusions. (1) Cell homogenates of Chlorella vulgaris adsorbed the inorganic arsenic compound Na2HAsO4 but no methylation of the arsenic occurred in vitro. (2) A small part of the arsenic bioaccumulated by C. vulgaris was methylated in vivo. The quantity of arsenic methylated in the cell increased with an increase of arsenic concentration in the medium. (3) When the arsenic-accumulating cells were transferred into arsenic-free media, the arsenic was excreted and the relative quantity of the methylated arsenic in the excrement was larger than that in the cell. (4) In the growth phase of C. vulgaris, a small fraction of the arsenic accumulated in the cell was first transformed to monomethyl and dimethyl-arsenic compounds during the early exponential phase, and after a short time a fraction was transformed to trimethylarsenic species. 相似文献
4.
Chronic toxicity, including tumorigenicity, of gallium arsenide (GaAs) and arsenic trioxide (As2O3) were studied using Syrian golden hamsters given intermittent intratracheal instillations. GaAs particles (0.25 mg × 15 times/animal) were likely to produce relatively severe lung damage and the survival of the animals was shortened significantly compared with a control group. The tumor incidence of each group examined was GaAs (3.3%), As2O3 (3.3%) respectively, at a dose of 3.75 mg total metal given during 15 weeks. In this experiment, both arsenic trioxide and gallium arsenide had no apparent carcinogenicity or tumorigenicity. 相似文献
5.
Mutsuo Ishizaki Seiichi Ueno Tadashi Okazaki Tomoko Suzuki Noritaka Oyamada 《应用有机金属化学》1988,2(4):323-331
The interaction of arsenic and selenium compounds on the metabolism of these elements in golden hamsters was studied. Golden hamsters were divided into three groups and administered sodium selenite (Na2SeO3), sodium arsenite (NaAsO2) and Na2SeO3 with NaAsO2, respectively, by a single Subcutaneous injection of 25 m?mol kg?1 body weight as As or Se (arsenic and selenium were calculated as weight of elemental arsenic and selenium). Selenium and arsenic metabolites were determined by high-performance liquid chromatography–graphite furnace atomic absorption spectrometry (HPLC–GFA AA) and gas chromatography (GC). The results show (1): About 10% by weight of the given dose of selenium was excreted in expiration air as dimethylselenide (Me2Se) during 12 h after administration of Na2SeO3. Excretion of dimethylselenide with the respiratory air was inhibited by administration of Na2SeO3 simultaneously with NaAsO2. (2) Giving Na2SeO3 plus NaAsO2 had no appreciable effect on the excretion of the trimethylselenonium ion (Me3Se+) into the urine and the feces. (3) Giving Na2SeO3 plus NaAsO2 increaed the excretion into the feces of an insoluble unknown-structure selenium compound, the proportion of which was 10.9% by weight of the given dose of selenium. (4) Giving NaAsO2 plus Na2SeO3 decreased the excretion of dimethylarsinic acid (Me2AsOOH) and inorganic arsenic into the urine during 120 h after the administration of the reagents, the decreased amount being 5.3% (dimethylarsinic acid) and 7.7% (inorganic arsenic) of the given dose of arsenic, respectively. (5) Giving NaAsO2 plus Na2SeO3 increased the excretion into feces of insoluble unknown-structure arsenic compound and inorganic arsenic, the increased amounts being 10.6% and 7.0% of the given dose of arsenic, respectively. (6) Giving NaAsO2 plus Na2SeO3 decreased the excretion into feces of extractable unknown-structure arsenic compound, and the decreased amount was 4.9% of the given dose of arsenic. (7) It made little difference to the excretion of monomethylarsonic acid [MeAsO(OH)2] into urine and feces and of dimethylarsinic acid (Me2AsOOH) into feces whether NaAsO2 was administered alone or with Na2SeO3. 相似文献
6.
The unicellular marine alga, Dunaliella salina 19/30 was grown in seawater containing an inorganic arsenic concentration (Na2HAsO4) up to 2000 mg dm?3. The cells survived even at 5000 mg dm?3. The arsenic concentration of the cells increased with an increase of the surrounding arsenic concentration. Arsenic in D. salina was also greatly affected by addition of phosphorus. The arsenic-tolerance behavior of D. salina seemed to suggest that the algae have a function to prevent accumulation of inorganic arsenic by increasing the β-carotene, fatty-acid (C18:1, C18:3) and water-extractable carbohydrate content in the cells. Arsenic accumulation also rose steadily with an increase in the nitrogen concentration in the medium. 相似文献
7.
Concerning Sodium Arsenites in the Three Component System Na2O? As2O3? H2O at 6°C Four phases Na2(H2As4O8) 1c , NaAsO2 · 4 H2O 2c , Na2(HAsO3) · 5 H2O 3c , and Na5(HAsO3)(AsO3) · 12 H2O 4c have been identified in the system Na2O? As2O3? H2O at 6°C and characterized by X-ray structural analysis. Polymetaarsenite anions, adopt in 1c and 2c , respectively, octet or doublet single chains. 相似文献
8.
To investigate the effect of cadmium on the accumulation of arsenic by Dunaliella sp., the arsenic accumulated in the alga was determined as a function of time for coexistence of the algae with arsenic and cadmium, with batch methodology. Growth of Dunaliella sp. was affected by addition of arsenic (Na2HAsO4.7H2O) and cadmium (CdCl.2.5H2O). Growth inhibition of Dunaliella sp. was accelerated by coexistence of arsenic and cadmium. The content of arsenic in Dunaliella sp. became a maximum at 15 h after exposure. The arsenic content in the cells was influenced by addition of cadmium to the solution; the arsenic content in the alga derived from growth in a 10 mg As dm ?3 solution decreased from 2.7 mg g?1 in the absence of cadmium to 0.35 mg g?1 for the addition of 100 mg Cd dm?3. Dunaliella sp. accumulated cadmium in large quantities but, in conditions of coexistence with arsenic and cadmium, the cadmium content in cells decreased with an increase in the concentration of arsenic in the growth medium Cadmium accumulation by Dunaliella sp. was observed in dead cells although arsenic accumulation was not observed. About 85% of arsenic in the cells was in the water-soluble fraction. On the other hand, about 42% of cadmium in the cells was in the water-soluble fraction, and about 55% was in a fraction soluble in cold trichloroacetic acid. 相似文献
9.
《Acta Crystallographica. Section C, Structural Chemistry》2018,74(6):721-727
The crystal structures of hydrothermally synthesized (T = 493 K, 7–9 d) rubidium aluminium bis[hydrogen arsenate(V)], RbAl(HAsO4)2, caesium iron bis[hydrogen arsenate(V)], CsFe(HAsO4)2, rubidium dialuminium arsenic(V) hexakis[hydrogen arsenate(V)], RbAl2As(HAsO4)6, and caesium diiron arsenic(V) hexakis[hydrogen arsenate(V)], CsFe2As(HAsO4)6, were solved by single‐crystal X‐ray diffraction. The four compounds with the general formula M+M3+(HAsO4)2 adopt the RbFe(HPO4)2 structure type (Rc) and a closely related new structure type, which is characterized by a different stacking order of the building units, leading to noncentrosymmetric space‐group symmetry R32. The second new structure type, with the general formula M+M3+2As(HAsO4)6 (Rc), is also a modification of the RbFe(HPO4)2 structure type, in which one third of the M3+O6 octahedra are replaced by AsO6 octahedra, and two thirds of the voids in the structure, which are usually filled by M+ cations, remain empty to achieve charge balance. 相似文献
10.
L. A. Sheludyakova V. A. Afanasieva N. V. Podberezskaya Yu. I. Mironov 《Journal of Structural Chemistry》1999,40(6):869-872
Anhydrous sodium hydrophosphates and arsenates and heptahxdrates were svnthesized and characterized by IR spectroscopy and
X-ray diffractometry. Anhydrous sodium hxdrophosphate and hydroarsenate were found to be isostmctural. Unit cell parameters
of Na2HAsO4 are calculated. Assignment of IR bands is given and comparative analysis of spectral and structural characteristics of the
compounds is performed. 相似文献
11.
Vigdorovich V. I. Tsygankova L. E. Kopylova E. Yu. 《Russian Journal of Electrochemistry》2003,39(7):753-759
Effect of arsenic compounds H3AsO4, H2AsO4
–, and HAsO4
2– on the hydrogen overvoltage, the slow stage of discharge of hydronium ions on the Armco iron, and the hydrogen diffusion through a steel membrane from aqueous and ethylene glycol solutions of hydrochloric acid with a constant ionic strength of unity is considered. 相似文献
12.
Determination and pharmacokinetic properties of arsenic speciation in Xiao‐Er‐Zhi‐Bao‐Wan by high‐performance liquid chromatography with inductively coupled plasma mass spectrometry
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Xu Han Jiaoyang Luo Wenju Zhou Shihai Yang Meihua Yang 《Journal of separation science》2016,39(20):3852-3859
A method of high performance liquid chromatography with a Hamilton PRP‐X100 ion‐exchange column (250 × 4.1 mm id, 10 μm) coupled to inductively coupled plasma mass spectrometry was employed to generate a full concentration–time profile of arsenic speciation after oral administration. The results exhibited good linearity and revealed that, in the pills, the average arsenic concentration was 10105.4 ± 380.7 mg/kg, and in the water extraction solution, the inorganic As(III) and As(V) concentrations were 220.1 ± 12.6 and 45.5 ± 2.3 mg/kg, respectively. No trace of monomethyl arsenic acid was detected in any of the plasma samples. We then successfully applied the established methodology to examine the pharmacokinetics of arsenic speciation. The resulting data revealed that, after oral administration in rats, the plasma concentration of each arsenic species reached Cmax shortly after initial dosing, and that the distribution and elimination of As(V) was faster than that of As(III) and dimethyl arsenic acid. Additionally, the t1/2 values of As(V), As(III), and dimethyl arsenic acid were 3.4 ± 1.6, 14.3 ± 4.0, and 19.9 ± 1.6 h, respectively. This study provides references for the determination of arsenic speciation in mineral‐containing medicines and could serve as a useful tool in measuring the true toxicity in traditional medicines that contain them. 相似文献
13.
《Journal of Inorganic and Nuclear Chemistry》1981,43(9):2043-2047
Two new forms of microcrystalline thorium arsenate have been synthesised. They have been characterised as Th(HAsO4)2·4H2O and Th(HAsO4)·2.5H2O by chemical analysis and thermal, X-ray, IR and ion exchange studies. The interlayer distances are: Th(HAsO4)2·4H2O: 8.23 Å and Th(HAsO4)2·2.5H2O: 8.59 Å. However, thermally and chemically, both these exchangers are less stable than Th(HAsO4)2·H2O; Th(HAsO4)2·2.5H2O being more stable than Th(HAsO4)·4H2O. The maximum lithium ion uptake and the corresponding arsenate released, respectively are: 1.75 and 1.20 mmol/g for Th(HAsO4)2·4H2O at pH 9.0 and 3.42 and 0.28 mmol/g for Th(HAsO4)2·2.5H2O at pH 11.8. For both exchangers, the loss of zeolitic water as well as that released on formation of thorium pyroarsenate takes place in one step between 383 and 773 K. 相似文献
14.
Lead(IV) acetate reacts with aqueous arsenic acid to yield lead(IV) arsenates, the state of which depends on the conditions of precipitation. At room temperature amorphous precipitates or gelatinous masses are obtained. Also clear solutions are obtained, which need sometime to become gelatinous. At 90°C colourless crystalline lead(IV) hydrogenarsenate-monohydrate, Pb(HAsO4)2 · H3O, is obtained, isotypic with lead(IV) hyrdrogen-phosphate-monohydrate. 相似文献
15.
The purpose of this study was to evaluate percutaneous penetration and arrhythmogenic effects of aconitine after transdermal administration, compared with the oral route. Skin penetration of aconitine was tested by a microdialysis technique in rats and in vivo recovery was determined by retrodialysis. After oral and transdermal administration of aconitine, dialysate was sampled at 20 min intervals until the end of the experiment for the determination of concentration of aconitine in skin. Blood samples were collected and analyzed using a validated HPLC‐MS/MS method. In addition, we concurrently recorded the electrocardiogram (ECG). The in vivo recovery of aconitine in the skin was calculated to be 39.59%. The Cmax values for aconitine absorbed into the skin after oral and transdermal administration were 1.51 ± 0.53 and 2723.8 ± 848.8 ng/mL, respectively, and within the plasma, 215.86 ± 79.29 and 20.92 ± 3.15 ng/mL. The Cmax value for the plasma concentration of aconitine after oral administration was approximately 10 times higher than with the transdermal route. For oral administration, the ECG revealed various types of arrhythmias at a period of Tmax, which is normal in transdermal gel administration. These results indicate that transdermal aconitine gel is a safe formulation that can deliver the drug in sufficient amounts and safe concentrations to produce therapeutic action in rats. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
16.
Issa M. El Nahhal Nasser Abu Ghalwa 《Journal of Dispersion Science and Technology》2013,34(6):876-882
A solid‐state glass/TiO2 electrode was fabricated using a transparent conductive titanium oxide film on a glass substrate. The coating of the glass substrate was achieved by a novel simple chemical vapor deposition (CVD) procedure. This electrode can be used as an indicator electrode in potentiometric acid‐base titration. This electrode behaves reversibly and responds to the oxide ion concentration in molten NaNO3 · Na2HAsO4, NaPO3, Na4P2O7, and their binary mixtures were potentiometrically titrated with Na2O2 as titrants in molten NaNO3 at 350°C, using the above mentioned indicator electrode. 相似文献
17.
《Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy》1992,48(10):1453-1458
IR and Raman spectra of Te(OH)6.2NH4H2AsO4.(NH4)2HAsO4 (compound I) and Te(OH)6.2(NH4)2HAsO4 (compound II) are recorded and analysed. The symmetry of different groups and the vibrational interaction between them are discussed. The observed spectra suggest the existence of HAsO2−4 in II and coexistence of HAsO2−4 and H2AsO−4 in I. The ammonium ion is found to execute hindered rotation in the lattice in both the compounds. 相似文献
18.
Matthias Weil 《无机化学与普通化学杂志》2014,640(1):128-135
Two modifications of (TeO)(HAsO4) were obtained by reacting tellurium dioxide with arsenic acid under boiling conditions (modification I, acid concentration 80 wt‐%) or under hydrothermal conditions (modification II, acid concentration 50 wt‐%). The crystal structures of the two modifications were determined from single‐crystal X‐ray data [modification I: P21/c, Z = 4, a = 7.4076(10), b = 5.9596(7), c = 9.5523(11) Å, β = 102.589(8)°, 2893 structure factors, 68 parameters, R[F2 > 2σ(F2)] = 0.0247, wR2(F2 all) = 0.0530; modification II: P21/c, Z = 4, a = 6.2962(4), b = 4.7041(3), c = 13.9446(8) Å, β = 94.528(3)°, 2549 structure factors, 69 parameters, R[F2 > 2σ(F2)] = 0.0207, wR2(F2 all) = 0.0462)]. Dehydration of (TeO)(HAsO4)‐II at temperatures above 260 °C results in the formation of polycrystalline (Te3O3)(AsO4)2. Single crystals of the anhydrous product were grown either by heating stoichiometric amounts of the binary oxides TeO2 and As2O5 in closed silica glass ampoules or with higher concentrated arsenic acid (80 wt‐%) under hydrothermal conditions at 220 °C. The common features in the crystal structures of (Te3O3)(AsO4)2 [P$\bar{1}$ , Z = 4, a = 6.5548(4), b = 7.6281(6), c = 15.0464(15) Å, α = 140.212(6), β = 102.418(9)°, γ = 77.346(5)°, 5718 structure factors, 146 parameters, R[F2 > 2σ(F2)] = 0.0351, wR2(F2 all) = 0. 1093] and in that of the two modifications of acidic (TeO)(HAsO4) are [TeO5] square‐pyramids and [AsO4] tetrahedra. In anhydrous (Te3O3)(AsO4)2 and in (TeO)(HAsO4)‐II, a layered arrangement of the building units is found, whereas in the (TeO)(HAsO4)‐I structure strands are formed. Different hydrogen bonding interactions are present in the two modifications of (TeO)(HAsO4). 相似文献
19.
M. Take M. Ohnishi S. Yamamoto M. Matsumoto K. Nagano S. Fukushima 《International journal of environmental analytical chemistry》2013,93(15):1715-1728
1,4-Dioxane is used in large amounts by industry. Human exposure to 1,4-dioxane is via both air and water. Recently we reported that the toxicity of chloroform is enhanced when exposure is by multiple exposure routes rather than a single exposure route. In this study, rats were exposed simultaneously to 1,4-dioxane by two routes, inhalation and oral, and the distribution of 1,4-dioxane in the blood, lung, liver, brain, kidney and abdominal fat of rats were determined. To assess the contribution of each route, unmodified 1,4-dioxane (DX) was administered by inhalation and deuterated 1,4-dioxane (DX-d8) was administered orally, and DX and DX-d8 were analyzed by mass spectrometer (MS). Exposure by both inhalation and oral administration resulted in DX and DX-d8 concentrations in the blood and tissues which were higher than when exposure was by either inhalation or oral administration alone. The distribution of 1,4-dioxane in the combined inhalation plus oral administration conformed with its physicochemical properties and the tissue partition coefficients. Our results support the well accepted tenet that when investigating the toxicity of a chemical, the route of exposure is an important consideration, and in addition, our results suggest that when exposure is by multiple routes, exposure by one route may, to some extent, have an affect on exposure by the second route. 相似文献
20.
Shivani Sharma Dr. Aamod V. Desai Dr. Biplab Joarder Dr. Sujit K. Ghosh 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2020,132(20):7862-7866
Selectively capturing toxic oxoanions of selenium and arsenic is highly desired for the remediation of hazardous waste. Ionic metal–organic frameworks (iMOFs) especially cationic MOFs (iMOF-C) as ion-exchange materials, featuring aqueous phase stability, present a robust pathway for sequestration of the oxoanions owing to their ability to prevent leaching because of their ionic nature. On account of scarcity of water-stable cationic MOFs, the capture of oxoanions of selenium and arsenic has been a major challenge and has not been investigated using iMOFs. Herein, we demonstrate large scale synthesis of cationic MOF, viz. iMOF-1C that exhibits selective capture of oxoanions of SeVI (SeO42−) and AsV (HAsO42−) in water with a maximum sorption capacity of 100 and 85 mg g−1, respectively. This represents among the highest uptake capacities observed for selenate oxoanion in MOFs. Further, the ion-exchange mechanism was directly unveiled by single crystal analysis, which revealed variable modes of host–guest binding. 相似文献