New epoxy acids ofGaleopsis bifida

Twelve epoxy acids have been detected in the seed lipids ofGaleopsis bifida Boenn. (family Lamiaceae). Their structures have been established by TLC, GLC, periodate-permanganate oxidation, hydrogenation, ORD, and UV, IR, and mass spectrometry. Three of them are known but this is the first time that they have been detected in this plant, and six of them are new. The absolute configurations of the two main epoxy acids have been determined.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 224–231, March–April, 1987.     

Fragmentation of some 1,2-epoxyguaianolides

The mass spectra of four guaianolides with epoxy groups of C₁–C₂ have been studied. A mechanism is proposed for the formation of the main ions. The origin of the secondary fragments has been confirmed by measurements of elementary compositions.Institute of the Chemistry of Plant Substances of the Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 796–800, November–December, 1980.     

GC-MS analysis of hydroxy and epoxy acids from seed oil of Hippopha? rhamnoides

By the GC-MS method using a packed column, in the mixture of TMS derivatives of hydroxy acid methyl esters obtained from the seed oil of the sea buckthorn, in ten chromatographic peaks (CPs) 13 monohydroxy compounds have been characterized by their mass spectra, the main ones being derivatives of dimorphecolic and coriolic acids. Structures are proposed for four dihydroxy acids of the C₁₇–C₂₀ series. The mixture of methyl esters of di- and tetra-TMS derivatives obtained from the mixture of epoxy acids from the same source has been analyzed by a similar method. In seven CPs, 11 compounds, reflecting the presence of nine epoxy acids in the initial mixture, have been characterized by their mass spectra. The main component of the mixture was 15,16-epoxyoctadeca-9,12-dienoic acid.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 626–634, September–October, 1989.     

Oxygenated fatty acids of the seeds ofElaeagnus angustifolia

Among the oxidized lipids in the seed oil of the oliveElaeagnus angustifolia we have detected six epoxy acids and five hydroxy acids, of these 12-hydroxyoctadeca-8,10-dienone being new.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 715–719, November–December, 1994.     

Neutral lipids of the seeds ofPhlomis oreophilla andPh. regelii

The lipid and fatty acid compositions of the seeds ofPhlomis oreophilla andPh. regelii (familyLabiatae) have been studied. The lipids ofPh. oreophilla are enriched with linoleic acid and those ofPh. regelii with oleic acid. Laballenic acid is present in the total acids of the triacylglycerides and the free fatty acids of both species, being concentrated in the free acids. The epoxy acids ofPh. oreophilla are represented by 9,11-epoxystearic, vernolic, coronaric, and 15,16-epoxylinoleic acids.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 561–565, September–October, 1983.     

X-ray structural investigation of gossypol and its derivatives. VIII. A new class of inclusion compounds based on dianilinegossypol

Summary The existence of a new class of ICs based on DAGP has been established. Single crystals have been obtained and the crystallographic characteristics of 15 ICs of this GP derivative have been determined.A. S. Sadykov Institute of Bioorganic Chemistry, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 666–669, September–October, 1988.     

Alkaloids ofPetilium eduardi. Petine and petine N-oxide

Two new alkaloids — petine and petine N-oxide — have been isolated from the bulbs of Petilium eduardi. Their structures have been established on the basis of spectral characteristics and chemical transformations.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, FAX (3712) 89-14-75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 524–528, July–August, 1994.     

Complex compounds based on a colchicine derivative

Complex compounds based on deacetyl-10-ethanolamino-10-demethoxycolchicine with Co, Mn, and Fe chlorides have been obtained, and their radiomodifying and antitumoral properties have been investigated.Tashkent State University, 700095, Tashkent, CIS, Vuzgorodok. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 728–730, September–October, 1996. Original article submitted November 5, 1994; revision submitted April 7, 1995.     

Epoxy acids of the seed oil ofArtemisia absinthium

Summary 1. The seed oil of the Central Asian common wormwood has yielded 1.48% of cis-12,13-epoxyoctadec-cis-9-enoic acid, 5.94% of cis-9,10-epoxyoctadec-cis-12-enoic acid, and traces of 9,10-epoxyoctadecanoic acid, and their structures have been confirmed.2. It is proposed to used the neutralization number of fatty acids to determine the amounts of epoxy acids in their combinations with -hydroxydienic acids.3. The possibility has been shown of determining the amount of ratio of the isomeric epoxy acids using oxidative degradation of the total oxy acids.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 705–710, November–December, 1976.     

X-ray structural investigation of a derivative of the alkaloid kesselringine

The molecular and crystal structures of 2,6-dimethyl-12-demethylkesselringine methosulfate have been determined by x-ray structural analysis. The relative configurations of the chiral centers in the R, S nomenclature have been established.Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent; V. I. Lenin State University, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 89–92, January–February, 1986.     

Alkaloids ofNitraria sibirica. Structure and absolute configuration of sibirinine

The chemical properties of sibirinine have been studied, its synthesis has been performed, and its¹H and¹³C NMR spectra have been analyzed. From the results obtained its structure and absolute configuration have been deduced.Institute of the Chemistry of Plant Substances of the Uzbek SSSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 685–689, September–October, 1987.     

Alkaloids ofRhinopetalum stenantherum. Structure of stenanzidine

Three new alkaloids have been isolated from the combined alkaloids of the epigeal part ofRhinopetalum stenantherum: stenanzidine, stenanzidinine, and stenanzamine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 341–344, May–June, 1984.     

Carbohydrates ofAlium. VII. Characteristics of the polysaccharides of the skin ofAlium cepa

The polysaccharides in the skin of the garden onion have been investigated. Their qualitative and quantitative compositions have been determined. The physicochemical characteristics of the pectin substances are given and the water-soluble polysaccharide is characterized.Deceased.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Samarkand Cooperative Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 14–17, January–February, 1985.     

Alkaloids ofNitraria komarovii XVII. Peganine N-oxide, N-allylschoberine, and dehydronitramidine

Three new alkaloids have been isolated from the epigeal part ofNitraria komarovii — peganine N-oxide, N-allylschoberine, and dehydronitramidine. Their structures have been determined on the basis of chemical transformations and spectral results.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 780–783, November–December, 1994.     

Polysaccharides of saponin-bearing plants. X. An investigation of the carbohydrates ofAcanthophyllum pungens

Polysaccharides have been isolated from the epigeal and hypogeal organs ofAcanthophyllum pungens and their qualitative presence and quantitative compositions have been determined. A neutral polysaccharide from the epigeal organs is of the galactan type, while a neutral polysaccharide from the roots is a glucogalactan.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 693–695, September–October, 1997.     

Hydroxy acids of the seed oils of five plants of the family Asteraceae

A comparative study has been made of the fatty hydroxy acids and epoxy acids of the seed oils ofArtemisia absinthium, Arctium tomentosum, Onopordum acanthium, Onopardum olgae, andCousinia severzovii by GLC, TLC, and IR and mass spectroscopy. It has been shown that the hydroxy acids present in largest amount are the products of the metabolism of 9-hydroperoxyoctadecadienoyl; the epoxy acids are represented mainly by 9,10-epoxy-cis-octadeca-12-enoic acid.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 30–34.     

Metabolites of the pathogenic fungusVerticillium dahliae III. The lipid composition ofVerticillium dahliae

Summary The compositions of the neutral lipids of the mycelium and of the culture liquid from the pathogenic fungusVerticillium dahliae Kleb. have been investigated for the first time. The fatty-acid compositions of the main lipid fractions and the glyceride composition of the triglyceride fraction have been determined. The main acids of all the fractions are the 16:0 and 18:1 acids and in the triglyceride fraction, additionally, the 18:2 acid. Diisobutyl phthalate has been found in the combined neutral lipids of the fungal mycelium.V. I. Lenin Tashkent State University, Institute of the Chemistry of Plant Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 431–435, July–August, 1976.     

Alkaloids of Aconitum sajanense I. Structure of acosanine

From the epigeal part of the previously unstudied plantAconitum sajanense we have isolated the new alkaloid acosanine, the structure of which has been established on the basis of spectral characteristics and has been confirmed by a direct comparison with a sample of demethyldelcorine.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 247–249, March–April, 1992.     

Arylnaphthalene lignans ofHaplophyllum dauricum. The structure of daurinol

The arylnaphthalene lignans justicidin B and daurinol I have been isolated from the epigeal part ofHaplophyllum dauricum (L.) G. Don.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 295–297, May–June, 1981.     

Primary structure of subunit B of the 11S globulin of cotton seeds of variety 108-F. III. Peptides from tryptic hydrolysis at arginine residues

To obtain peptides overlapping the lysine peptides obtained by complete tryptic hydrolysis, cleavage of maleylated subunit B with trypsin at arginine residues has been performed. Large peptides containing lysine have been obtained and characterized.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 224–227, March–April, 1984.